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UK medicines manufacturing to get innovation boost

European Pharmaceutical Review

According to UK Research and Innovation ( UKRI ), £13 million is set to fund medicine manufacturing in the UK, through a focus on innovation in intracellular drug delivery, digitalisation and automation and nucleic acid medicines. This will overall increase the ease of manufacture and reduce costs.

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New UK intracellular drug delivery centre to support RNA development

Pharmaceutical Technology

A new intracellular drug delivery centre will be established in the UK to support potential ribonucleic acid (RNA) vaccines and therapeutics , as well as the development of innovative drug delivery technologies. The funding is being provided under the agency’s Transforming Medicines Manufacturing programme.

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Merck and Orna partner for RNA technology-based vaccines and therapies

Pharmaceutical Technology

By self-circularisation, Orna’s oRNA technology makes circular ribonucleic acids (oRNAs) from linear RNAs. Topic sponsors are not involved in the creation of editorial content. These programmes will include therapies and vaccines in infectious disease and oncology areas.

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mRNA therapeutics: a limitless revolution in medicine

European Pharmaceutical Review

Advances in mRNA technologies and cellular delivery systems coupled with their cost effectiveness, manufacturing simplicity and ability to target previously-undruggable pathways has limitless potential that could revolutionise medicine. Manufacturing time for mRNA therapeutics is also fast compared to antibodies or protein-based drugs.

Vaccines 103
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Porton raises funds for gene and cell therapy CDMO platforms expansion

Pharmaceutical Technology

Porton Advanced Solutions has raised $80m in a Series B funding round to expand its end-to-end gene and cell therapy (GCT) contract development and manufacturing organisation (CDMO) platforms. By the end of this year or earlier next year, Porton will have a PD, AD and GMP manufacturing facility spread over more than 200,000ft² for GCT. .

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National Resilience secures funding for domestic biomanufacturing capacity

Pharmaceutical Technology

National Resilience will use the funding to establish a significant domestic biomanufacturing capacity and capabilities for vaccines, nucleic acids including mRNA, and biologics including antibodies, proteins and multi-specifics. Topic sponsors are not involved in the creation of editorial content.

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Transforming Biomanufacturing: Potential of Cell Free Systems

Roots Analysis

These expression systems utilize bio machinery harvested from the lysate of disrupted cells for the manufacturing of a wide array of macromolecular and small molecule products. Overview of Cell Free Systems Cell-free systems are ­in-vitro platforms which allow occurrence of biochemical reactions in the absence of living cells.