Remove topic excipients
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Krystal Biotech receives FDA approval for DEB topical gene therapy

Pharmaceutical Technology

Krystal Biotech has received approval from the US Food and Drug Administration for topical gene therapy VYJUVEK to treat dystrophic epidermolysis bullosa (DEB) in adults and in children aged six months and above. Topic sponsors are not involved in the creation of editorial content.

FDA 105
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Enhancing bioavailability in ocular drug delivery

European Pharmaceutical Review

Currently, effective topical administration is challenging as the industry aims to prolong drug residence time and guarantee appropriate ocular permeation. How to enhance ocular drug bioavailability One approach to enhance drug bioavailability after topical administration is increasing corneal permeability.

Dosage 75
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Novaliq’s dry eye disease therapy receives US FDA approval

Pharmaceutical Technology

VEVYE, the development name of which is CyclASol, is a cyclosporine, solubilised solution in a new, water-free excipient. CyclASol is topical anti-inflammatory and immunomodulating ophthalmic drug solution containing 0.1%

FDA 98
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Roquette opens pharmaceutical innovation facility in Pennsylvania, US

Pharmaceutical Technology

In the first phase of its training workshops, the Pharmaceutical Innovation Center plans to develop a range of excipients [inactive substances that serve as the vehicle or medium for a drug or other active substance] for controlled release dosage forms, improving their bioavailability, along with formulating orally dispersible and chewable tablets.

Dosage 52
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RT-002 by Revance Therapeutics for Upper Limb Muscle Spasticity: Likelihood of Approval

Pharmaceutical Technology

It is investigating its lead candidate, daxibotulinumtoxinA, a topical gel formulation as a needle-free approach for a wide range of therapeutic and aesthetic indications, such as chronic migraine, facial wrinkles and muscle disorders. Revance Therapeutics is headquartered in Nashville, Tennessee, the US.

52
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RT-002 by Revance Therapeutics for Upper Limb Muscle Spasticity: Likelihood of Approval

Pharmaceutical Technology

It is investigating its lead candidate, daxibotulinumtoxinA, a topical gel formulation as a needle-free approach for a wide range of therapeutic and aesthetic indications, such as chronic migraine, facial wrinkles and muscle disorders. Revance Therapeutics is headquartered in Nashville, Tennessee, the US.

52
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Pharmaceutical industry: 2023 in retrospect

European Pharmaceutical Review

Conclusions Of the five major topics covered during 2023, it is likely that all will feature to a greater or lesser extent during 2024. Reactive impurities in excipients: profiling, identification and mitigation of drug-excipient incompatibility. Lessons learnt from presence of N-nitrosamine impurities in sartan medicines.

FDA 96