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Free access to Zolgensma curbed, says Novartis

pharmaphorum

Novartis’ programme providing free access to its spinal muscular atrophy (SMA) gene therapy Zolgensma is being scaled back to a dozen countries worldwide, according to the company. ” Zolgensma is one of the most expensive therapies available, with a price tag of around $2.1 Pause in UK access.

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Risk-sharing agreements are growing at a rate of 24%

Pharmaceutical Technology

This is not the first treatment to come with a high price tag. Countries with a high willingness for performance-based models, such as the UK, saw this RSA type peak in 2019 before continually declining. Undoubtedly, this has played a factor in the success of market-leading PD-1 inhibitors, Merck & Co.’s

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Orphan drugs and where to launch them: The keys to Europe’s forgotten territories

Pharmaceutical Technology

The commercial investment required to research and develop an innovative drug, prove its safety and efficacy, and bring it to market is staggering. Go-to-market strategies. The challenge of providing adequate access to the peripheral EU markets is quite evident. Efforts have been made to change this.

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NICE says yes to Novartis’ multiple sclerosis therapy Kesimpta

pharmaphorum

Novartis has secured backing from NICE for its relapsing multiple sclerosis (RMS) therapy Kesimpta in the UK, just two weeks after the drug was approved by the national drugs regulator. . There are around 130,000 people with MS in the UK, with 7,000 new diagnoses a year. billion by 2028. billion by 2028. billion in sales in 2028.

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Cannabinoids receptors: popular preclinical target but banned in 137 countries

Pharmaceutical Technology

Collectively, cannabinoid receptors (CB1 and CB2) are currently the most popular targets in preclinical stage of development, with 391 drugs tagged in total. In the US, the world’s largest pharmaceutical market, most states have legalized cannabinoids for medical use. This is closely followed by CB2 receptors in second place.

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3 ways pharma marketers can draw inspiration from digitally-native brands

pharmaphorum

As pharmaceutical marketers prepare their brands for the future, there are a number of important ways they can learn from digitally-native brands. This is reinforced by web-focused marketing strategies that give them a highly-targeted approach when it comes to marketing execution.”. Be more agile .

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A broad range of unmet needs remains in the immuno-oncology space

Pharmaceutical Technology

There are more than 20 marketed ICIs with approvals across a very wide spectrum of solid tumour indications. Marketed bispecific antibodies are largely bispecific T-cell engagers (BiTEs), which work by directing T-cells to antigen-expressing tumour cells. Cost-related unmet needs also scored highly.