Remove tag translational-research
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Rare Disease Spotlight – tracing the rise of orphan drug designations over almost 40 years

Pharmaceutical Technology

Research and drug development for rare diseases has shifted from “niche” to conventional, aided by multiple drivers of growth in the field and favorable legislation. An orphan drug designation does not automatically translate into approval. What happens after a drug gets an orphan drug designation?

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Orphan drugs’ financial success raises questions

pharmaphorum

And of course, in many cases, these drugs have higher than average price tags compared to the wider market which is due to the limited – or in most cases – non-existent competition within a treatment area.”. Raising questions. Reaching a compromise. The post Orphan drugs’ financial success raises questions appeared first on.

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Top Commercial Benefits of Modular Approach

Viseven

Metadata tagging allows searching for a needed piece of delivery faster and easier than usual research on the content subject. Modular content works perfectly for both cases, as it helps to collect the whole library of templates filled with unique meta tags for quick search.

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Spatial Genomics, Transcriptomics and Proteomics Solutions – An Amelioration of Tissue Analytics

Roots Analysis

Recent advances in multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, cytometry and imaging, in combination with bioinformatics and biostatistics, have been translated into several popular bioanalytical platforms, such as next-generation sequencing (NGS), single-cell analysis, flow cytometry and mass spectrometry.

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Putting complex medicines under the microscope

European Pharmaceutical Review

The biological characterisation of complex medicines is fundamental to translate these novel therapeutics and associated drug delivery technologies into the clinic; to understand the interplay with biological systems and to evaluate new formulations?. Modifying or developing targeting moieties is necessary to improve extrahepatic delivery.

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CEPI provides $30m to advance novel coronavirus vaccine

European Pharmaceutical Review

These coronavirus RBDs are attached to a nanoparticle by protein tags, enabling the structure to display fragments from multiple viruses on a single nanoparticle. . The pre-clinical research published in Science demonstrates that the mosaic?8 The innovative protein ?“glue” Initial development and validation of the prototype mosaic?8

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Conjugation and Labeling of Molecules: A Burgeoning Approach in Therapeutics Development and Molecular Imaging

Roots Analysis

These molecules can be conjugated with various modalities, such as haptens, enzymes, isotopes, fluorescent tags, carrier proteins, polymers, particle conjugates and photoreactive molecules. Bioconjugation is a subset of conjugation where one of the entity is a biomolecule, such as protein or an antibody.