Pharmaceutical Technology

MAY 2, 2023

IO therapies come with a hefty price tag, with ICI therapies in the US typically exceeding $100,000, while cell therapies can exceed $400,000. There were also personalised care-related unmet needs identified, and this included the need for better predictive biomarkers. Cost-related unmet needs also scored highly.

Immunization 52

Immunization Vaccines 52

pharmaphorum

DECEMBER 23, 2022

price tag of $475,000 when it was first launched in 2017 – and it becomes apparent that these may not be desirable treatment options for every patient and in every setting. Among the patients treated at the RP2D, six out of seven had reduction or stabilisation of serum-free light chains – a biomarker that indicates the presence of myeloma.

Immunization 52

Immunization Hospitals Vaccines 52

pharmaphorum

JUNE 8, 2021

ICER argues that Aduhelm was effectively approved on the strength of a biomarker – removing amyloid from the brain – rather than clinical outcomes, which is “puzzling” as other drugs have been shown to remove amyloid from the brain yet failed to help patients. .” billion in 2027.

FDA 98

FDA Labelling 98

European Pharmaceutical Review

NOVEMBER 10, 2022

For example, many small molecules can pass through the plasma membrane by diffusion to reach their target, whereas the tissue penetration, cellular uptake and intracellular trafficking of complex medicines can be difficult to predict. Physical characterisation.

Labelling 96

Labelling Compounding 96