Remove tag assays
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Putting complex medicines under the microscope

European Pharmaceutical Review

BT-474 cell line was gene-edited to incorporate a green fluorescent protein (GFP) tag into late endosomes/lysosomes (green). In vitro characterisation of complex medicines has traditionally been done using end-point assays to measure efficacy, which is similar to the method used for small molecules. Physical characterisation.

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Spatial Genomics, Transcriptomics and Proteomics Solutions – An Amelioration of Tissue Analytics

Roots Analysis

Furthermore, several live cell imaging and non-destructive fluorescence histological methods measure limited number of biomarkers at a time and the tags introduced may interfere with the natural function of genes and proteins. In fact, platform integration agreements account for 18% of the total deals inked in this domain, since 2016.

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