European Pharmaceutical Review

NOVEMBER 10, 2022

Complex medicines offer diverse therapeutic modalities, including RNA therapeutics and antibody-drug conjugates (ADCs). Advanced light microscopy techniques are one tool that can be used to understand these medicines. Improved analysis pre-clinically via advanced light microscopy could help. What constitutes a complex medicine?

Labelling 105

Labelling Compounding 105

Roots Analysis

SEPTEMBER 13, 2023

These molecules can be conjugated with various modalities, such as haptens, enzymes, isotopes, fluorescent tags, carrier proteins, polymers, particle conjugates and photoreactive molecules. Bioconjugation is a subset of conjugation where one of the entity is a biomolecule, such as protein or an antibody.

Labelling 40

Labelling 40

Roots Analysis

MAY 21, 2024

The promise of induced protein degradation as a novel therapeutic modality has attracted considerable attention in the pharmaceutical industry. This modality responsible for degradation of proteins is known as protein degraders. The following figure presents some of the advantages offered by targeted protein degraders.

Immunization 40

Immunization 40

European Pharmaceutical Review

AUGUST 24, 2022

While this led to successful ADC product approvals, it became clear that the resulting narrow therapeutic windows hampered the use of the modality for broader targets and indications. tag ® , inspired by the unique features of microtubule biology and perfectly suited for DAR 2 and DAR 4 ADCs.

Pharmaceutical Companies 104

Pharmaceutical Companies Pharmaceutical Companies Compounding 104