Sat.May 18, 2024 - Fri.May 24, 2024

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Optimizing Pharmaceutical Innovation Through AI: A Pathway to Expedited Drug Discovery and Development

Pharmacy Times

Clinical trials are using AI to handle large and complex volumes of data to develop oncology, cardiovascular, and neurologic compounds and to integrate molecular and imaging data.

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Slideshow: Mental Health Burden of Food Allergy, Nutritional Intervention May Help Children

Drug Topics

Recent research on food allergy highlights the mental health concerns of people living with a food allergy, how nutritional intervention can help children with food allergy, and that peanut introduction can reduce rates of new allergy in high-risk infants.

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New evidence supports fear that drinking raw milk containing bird flu viruses may be dangerous

STAT

A new study published Friday provides more evidence of the potential danger of drinking unpasteurized, or raw, milk containing H5N1 avian flu viruses. The work , published in the New England Journal of Medicine, showed that mice that were fed milk from H5N1-infected cows became very ill.

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Epic releases open-source AI validation tool for health systems

Fierce Healthcare

Epic launched an open-source tool on Wednesday to enable healthcare organizations to test and monitor artificial intelligence models. | Six weeks after announcing it was developing an AI validation software tool for healthcare, Epic has launched the open-source tool on Github to help health systems test and validate AI models.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Counsel Patients on Nutrition and Following a Balanced Diet Complementary to GLP-1s

Pharmacy Times

The GLP-1 market is expected to exceed $100 billion by 2023, according to J.P. Morgan Research, with total users in the United States projected to reach 30 million.

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Study Reveals Robust Benefits of Semaglutide in Protecting Against Kidney, CV Events in Patients With T2D

Drug Topics

Semaglutide reduced the risk of major kidney disease and cardiovascular (CV) events, and death from any cause, while simultaneously decelerating the loss of kidney function, among patients with type 2 diabetes (T2D) and CKD compared to placebo.

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More Trending

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UPMC's layoffs were the start of a McKinsey-guided 'transformation,' documents show

Fierce Healthcare

A wave of employee layoffs that UPMC announced last month was just one part of a broader restructure and operations “transformation” initiative, for which the nonprofit system has tapped management | An internal presentation obtained by Fierce Healthcare outlined April's “tough, but necessary" layoffs as one part of a broader look at the nonprofit system's operations, for which it has partnered with the consulting firm McKinsey & Company.

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Health Care Shortage Calls for Diversifying the Role of Community Pharmacists in Treatment of Minor Ailments

Pharmacy Times

New research study reveals the potential of community pharmacists for minor ailment treatment, allowing for diversified patient care during growing health care shortage.

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Obesity is Common in Individuals with Celiac Disease

Drug Topics

In an abstract presented at Digestive Disease Week 2024, researchers analyzed the prevalence of obesity in patients with and without celiac disease.

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Michigan reports a human case of bird flu, the nation’s second linked to H5N1 outbreak in dairy cows

STAT

A second human case of bird flu infection linked to the current H5N1 outbreak in dairy cows has been detected, in a farm worker who had exposure to infected cows, Michigan state health authorities announced on Wednesday. In a statement , health officials said the individual had mild symptoms and has recovered. Evidence to date suggests this is a sporadic infection, with no signs of ongoing spread, the statement said.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Cadence finds reduced cost and better outcomes for heart failure patients through remote monitoring program 

Fierce Healthcare

A new paper published in the Journal of Cardiac Failure shows that patients on Cadence’s remote physiologic monitoring program had better outcomes than patients eligible for the program wh | Deaths from heart failure are rising. National remote monitoring company Cadence published new evidence that RM for heart failure with reduced ejection fraction (HFrEF) could be the missing link in heart failure treatment.

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Program Highlights Opportunities for Community Pharmacies to Deliver Screening, Education, and Referral Interventions

Pharmacy Times

Aligning community pharmacy interventions with top-down findings, payers’ population health priorities, and identified unmet needs can help develop a sustainable pathway.

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Type 2 Diabetes Impacts Mental Health, but Continuous Glucose Monitors Can Help

Drug Topics

A report from Dexcom found that depression and anxiety are commonly reported in patients living with type 2 diabetes, but continuous glucose monitors can make disease management easier.

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UnitedHealth argues algorithm lawsuit should be dismissed because patients didn’t spend years appealing denials

STAT

UnitedHealth Group should be released from a lawsuit that alleges its algorithm-based technology prematurely cut off care to its Medicare Advantage members, the company said in court filings this week, because patients and their families did not finish Medicare’s appeals process. “Plaintiffs have failed to exhaust the exclusive administrative appeal process set by the Medicare Act,” UnitedHealth’s lawyers argued.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Atropos Health lands $33M to scale AI-powered real-world evidence, build out pharma partnerships

Fierce Healthcare

Atropos Health, maker of a real-world data platform, sits at the intersection of two rapidly growing fields, real-world evidence research and artificial intelligence. | Atropos Health is getting closer to its mission of addressing the evidence gap in healthcare and secured $33 million in series B funding to help fuel its growth.

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Sotorasib Plus Panitumumab Significantly Improves Outcomes in Colorectal Cancer

Pharmacy Times

Combination treatment of sotorasib plus panitumumab prolongs progression-free survival in those with metastatic colorectal cancer and the KRAS G12C mutation.

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Q&A: What Pharmacists Need to Know About Tianeptine

Drug Topics

Savannah Roberts Clary, PharmD, BCPS, CPGx, a clinical pharmacist with Aegis Sciences Corporation, discusses what tianeptine is and how pharmacists can help warn the public about its potential hazards.

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Wastewater testing specifically for bird flu virus will scale up nationally in coming weeks

STAT

Less than a month ago, researchers reported for the first time the ability to scan wastewater for signs of the H5 influenza virus currently sickening dairy cows in at least nine states across the U.S. That technology is now at the threshold of real-world use. WastewaterSCAN, an infectious disease-tracking sewage surveillance network led by Stanford University and Emory University in partnership with Verily Life Sciences, has begun scaling up H5-specific testing of samples from all of its 190 sit

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Express Scripts, CPESN team up to support independent pharmacies in providing key services

Fierce Healthcare

Express Scripts will partner with CPESN in the latest evolution of its IndependentRx Initiative, which aims to boost independent and community pharmacies. | Express Scripts will partner with CPESN in the latest evolution of its IndependentRx Initiative, which aims to boost independent and community pharmacies.

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Public Health Matters: Getting Involved With State Pharmacy Associations, Advocating for Pharmacists, Promoting Professional Development

Pharmacy Times

Tune into this episode of “Public Health Matters” to hear Dr. Kate Gainer’s journey in state pharmacy association and how advocacy and legislative initiatives can benefit pharmacists.

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Post COVID-19 Condition: The Frustrating Fight for Recognition and Treatment

Drug Topics

Health care providers must listen to patients who voice their experiences with post–COVID-19 condition symptoms. Only then can a clearer picture of the condition emerge for the millions of patients who have the near-invisible disease.

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When should we start making H5N1 vaccine, and who will make that decision? In short, it’s complicated

STAT

If the H5N1 bird flu virus ever acquires the ability to transmit easily to and among people — keep your fingers crossed that it doesn’t — the world is going to need serious amounts of vaccine. Like, lakes of the stuff. Some manufacturers have been working with H5N1 viruses for years, producing small batches of doses that have undergone preliminary human testing.

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Hospitals grapple with generic drug supply shortages

Fierce Healthcare

In this week’s episode of “Podnosis,” we’re diving into the issue of generic drug shortages. | In this week's "Podnosis" episode, Fierce Healthcare’s Dave Muoio talks with Allan Coukell from Civica Rx about generic drug shortages. Coukell discusses the impact on healthcare providers, recent strategies to strengthen the drug supply chain and advice for organizations facing these shortages.

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FDA Grants Tina-qant Lp(a) Assay Breakthrough Device Designation

Pharmacy Times

A lipoprotein (a) (Lp[a]) assay has been granted breakthrough device designation to expand identification of patients with elevated Lp(a) and genetic predispositions to cardiovascular disease.

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Pharmacists Play Key Role in Warning Public About Dangers of Tianeptine Misuse

Drug Topics

Savannah Roberts Clary, PharmD, BCPS, CPGx, a clinical pharmacist with Aegis Sciences Corporation, talks about the dangers of tianeptine and how pharmacists can help warn the public about the potential hazards of tianeptine.

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How doctors are pressuring sickle cell patients into unwanted sterilizations

STAT

BATON ROUGE, La. — The surgery was supposed to alleviate worry, but now, years later, Whitney Carter’s mind kept flicking back to it, wondering if it could be undone. She sometimes descended into these moods, taciturn, withdrawn, as if all hope had gone extinct. She sat on the couch in the half-light, blinds shut against the heat. The whole thing made her feel less than, like some essential part of her had been removed.

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Hims & Hers expands weight loss program to include access to GLP-1 medications

Fierce Healthcare

Six months after launching its weight loss program, online health and wellness company Hims & Hers added compounded GLP-1 medications to its offerings. | Six months after launching its weight loss program, online health and wellness company Hims & Hers added compounded GLP-1 medications to its offerings.

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Advancement in CAR T Cell Therapy for Patients with Multiple Myeloma Helps Predict Treatment Response and Resistance

Pharmacy Times

Researchers from the University of Leipzig Medical Center identify multiple biomarkers associated with the success of CAR T cell therapy in relapsed multiple myeloma.

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Latest Ozempic results 'move the needle' for treating patients with diabetes, chronic kidney disease: Novo exec

Fierce Pharma

While it’s hard to overstate the success Novo Nordisk’s GLP-1 franchise has already achieved, the company’s latest deep dive into semaglutide data in chronic kidney disease (CKD) could help set a n | Early Friday, Novo shared full, positive results from the FLOW trial assessing the ability of once-weekly semaglutide 1.0 mg to help combat major kidney outcomes such as kidney failure, loss of kidney function and death from kidney or cardiovascular causes in people with Type 2 diabetes and chronic

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Move over, wastewater. Store-bought milk could be another way to track the bird flu outbreak in cows

STAT

Scientists from the University of Washington and the Fred Hutchinson Cancer Center have managed to generate a full genetic sequence of H5N1 virus from milk, a development they suggest means commercially purchased milk products could be used to monitor the progress of the bird flu outbreak in dairy cattle and to check for important changes in the virus over time.

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HHS' ARPA-H offering more than $50M for hospital cybersecurity platform pitches

Fierce Healthcare

The Department of Health and Human Services’ (HHS’) research funding agency is floating more than $50 million to developers who can build a scalable cybersecurity platform able to keep hospitals' c | The UPGRADE program will be handing out millions to those with the best pitches on how to detect hospital cybersecurity weaknesses and deploy fixes with minimal interruptions to care delivery.

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Study Finds Semaglutide Improves Chronic Kidney Disease in Patients With Type 2 Diabetes

Pharmacy Times

The role of semaglutide as a glucagon-like peptide-1 (GLP-1) receptor antagonist could offer further treatment options to improve patient outcomes.

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At long last, AstraZeneca, Pfizer, J&J, Roche and others have an ally in Biden

Fierce Pharma

Over the last four years, with President Joe Biden milking a popular cause as an opponent of Big Pharma drug pricing, the industry has rarely seen good news coming from the White House. | Over the last four years, with President Joe Biden milking a popular cause as an opponent of Big Pharma's pricing, the industry has rarely seen good news coming from the White House.

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CDC asks states and cities to keep flu surveillance at peak levels because of bird flu threat

STAT

The Centers for Disease Control and Prevention asked local and state health officials Tuesday to maintain flu surveillance operations at peak-season levels over the summer in a bid to remain watchful for any signs of human-to-human spread of the H5N1 bird flu virus. Flu surveillance activity is generally conducted at low levels during the late spring and summer months, in recognition of the fact that as temperatures rise, transmission of seasonal flu viruses drops to minimal levels in the Northe

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