Sat.Dec 30, 2023 - Fri.Jan 05, 2024

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The race for obesity drug assets heats up

pharmaphorum

The race for obesity drug assets is becoming more intense as pharmaceutical companies strive to develop effective treatments for weight loss. This article explores the efficacy, potential sales, and market trends in the field of obesity drugs.

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Prescribing Success: Dr. Linda Gutierrez-Miller’s Journey to Impactful Clinical Pharmacy and Inspiring Resilience!

Pharmacy Is Right For Me

“How can I make the biggest difference in the lives of others? How can I help the most people?” These questions often cross the minds of students as they navigate the labyrinth of career choices. Dr. Linda Gutierrez-Miller, one such student, embarked on a journey to answer these questions, ultimately choosing a career path that aligns with her goals of making a substantial impact and aiding a diverse range of individuals—clinical pharmacy.

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Paxlovid Found Not to Reduce Long COVID Risk

Drug Topics

A new study found that 16.1% of patients treated with nirmatrelvir-ritonavir (Paxlovid) reported long COVID symptoms, compared to 14% of untreated patients.

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Statins Could Potentially Slow Deterioration of Cognitive Function for Those With Alzheimer Disease

Pharmacy Times

Due to the observational nature of the study, the study authors said they cannot determine causal relationships between statins and cognitive decline for patients with Alzheimer disease.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Opinion: Insurance companies are forcing psychiatrists like me to stop accepting their coverage

STAT

“I’m sorry, but I’m unable to take on new patients at this time.” I’ve said that line hundreds of times in the 15 years since I started my solo private practice in psychiatry. I feel terrible each time I say it. Someone on the other end of the phone is suffering and has taken the difficult step to call for help — probably multiple calls, given the longstanding shortage of psychiatrists — and yet I added to their hopelessness.

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Millions of doses of Pfizer's Paxlovid will go to waste in UK, EU as COVID demand plummets

Fierce Pharma

On the heels of a major Paxlovid inventory write-off in the United States, many more doses of Pfizer's COVID-fighting antiviral are going to waste overseas. | At the end of November, more than 1.5 million courses of Pfizer’s Paxlovid had expired unused in European countries, analysts at Airfinity said in a new report. The total tally of expired doses in Europe is expected to hit 3.1 million by the end of next month, representing a value of $2.2 billion.

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Poor Sleep Quality in Early Adulthood Linked With Worse Cognitive Performance in Middle Age

Pharmacy Times

The risk of poor cognitive performance was nearly double in participants who had the greatest number of sleep disturbances compared to the least.

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STAT+: Texas taxpayers wanted to help the poor get health care. Instead, they’re funding a medical school at a wealthy university

STAT

AUSTIN, Texas — Eleven years ago, local officials promised voters in the most liberal county in Texas that if they supported tens of millions of dollars in new taxes, they’d deliver a win-win scenario: Austin would get a new medical school, and poor people navigating the health care system in a state with the country’s worst uninsured rate would get more health care services.

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Amid Biden admin's drug-pricing push, Big Pharma kicks off 2024 with hundreds of price hikes: report

Fierce Pharma

While public and political scrutiny around drug pricing has reached a fever pitch in the wake of 2022’s Inflation Reduction Act (IRA), that hasn’t stopped pharma majors from ringing in 2024 with th | While public and political scrutiny around drug pricing has reached a fever pitch in the wake of 2022’s Inflation Reduction Act (IRA), that hasn’t stopped pharma majors from ringing in 2024 with their favorite New Year tradition: a hefty round of price hikes.

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Hospitals Reinstate Mask Guidelines Against Triple Threat of Respiratory Illnesses

Drug Topics

In response to a surge in cases of COVID-19, flu, and RSV, hospitals are reinstating mask guidelines to avoid adverse capacity outcomes and staffing shortages seen in prior years.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Pharmacists Play Crucial Role in Antimicrobial Stewardship

Pharmacy Times

Available data indicate that as much as 50% of all antibiotics prescribed for individuals may be either unnecessary or not administered in the most effective manner as recommended.

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How opioid overdoses in public restrooms led an electrician to invent ‘safe bathrooms’

STAT

First, a light starts to flash. Then a high-pitched siren starts to blare. Then come the sounds of nearby doors being flung open, and the frantic footsteps of doctors and nurses rushing toward a restroom at the end of a hallway. They’re in a hurry for good reason. These distress signals have a specific meaning: Somebody in the bathroom is overdosing.

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Novo Nordisk, Eli Lilly's weight-loss drugs under FDA scrutiny for suicidal thoughts, hair loss

Fierce Pharma

Use of Novo Nordisk and Eli Lilly’s popular diabetes and weight loss drugs come with warnings about a rare intestinal blockage condition called ileus, which can be life threatening. | Use of Novo Nordisk and Eli Lilly’s popular diabetes and weight loss drugs come with warnings about a rare intestinal blockage condition called ileus. Could cautions about more common side effects soon be added to the labels of popular treatments such as Novo’s Ozempic and Lilly’s Mounjaro?

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RSV Vaccine Coverage Similar to Flu Could Reduce Illness, Cost Burden

Drug Topics

A model showed that if a vaccine coverage of 66% were achieved—similar to flu vaccination coverage—it could have a budget impact of $6.48 to $6.78 billion over the first RSV season.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Study: Low RSV Vaccination Coverage Among Nursing Home Residents

Pharmacy Times

The study highlights the ongoing need for health care providers to recommend respiratory illness vaccinations to increase protection among nursing home residents during the peak season of infection.

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STAT+: Goldman Sachs launches $650 million fund for life science investments

STAT

Investment bank Goldman Sachs is jumping into the biotech world after raising $650 million to invest in privately held startups. The bank announced Wednesday that it has closed its first-ever life sciences fund, called West Street Life Sciences I. The plan is to invest the money in genetic medicine, cell therapies, immunotherapies, synthetic biology and artificial intelligence startups, as well as diagnostics and life science tools companies.

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JPM24, Day 2: BioNTech warns of COVID vaccine sales decline; Alnylam looks to become 'top-tier' biopharma player

Fierce Pharma

As the J.P. | As the J.P. Morgan Healthcare Conference rolled on in San Francisco, BioNTech, Alnylam and many other companies updated investors on their strategies heading into 2024.

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Moderate Carbohydrate Diet May Improve Glucose Control in Patients With T1D

Drug Topics

Patients on a moderate carbohydrate diet increased their time in range by 4.7% and decreased their time above range by 5.9%.

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Proposed Biosimilar Liraglutide Shows Non-Inferiority to Reference Drug for Type 2 Diabetes

Pharmacy Times

Liraglutide, a glucagon-like peptide 1 receptor agonist, has shown a clinically and significant reduction in glycated hemoglobin for those with type 2 diabetes.

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STAT+: Here’s who’s profiting the most in health care

STAT

For all the flack they get, the country’s four biggest pharmacy benefit managers reported a surprisingly tame average profit margin in the first three quarters of 2023: 4.5%, less than a third of their drugmaker peers. But don’t take their numbers as gospel, experts warned. “It’s really easy to move money around inside the books of a vertically integrated organization,” said Karen Van Nuys, a senior fellow at the USC Schaeffer Center for Health Policy and Econo

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Why amplifying the patient voice is crucial to clinical trial success

pharmaphorum

Amplifying the patient voice is essential for the success of clinical trials. Learn why it is crucial for patient engagement, recruitment, and overall trial success, and how it can address challenges such as transportation and financial barriers.

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Positive Results Announced From Phase 3 Trial of Oral Weekly Risperidone for Schizophrenia

Drug Topics

The Starlyng-1 study showed that the treatment met its primary endpoint of a one-sided Cmin of >0.80; a one-sided Cmax of <1.25; and a two-sided Cavg of 0.80-1.40, with 90% confidence limits.

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Immune Cells Shape Lung Development and Growth, Allow Developments for Treatment of Asthma, COPD

Pharmacy Times

The new understanding of immune cells could not only contribute to the development of lung disease treatments, but treatments for other organ systems as well.

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STAT+: Feng Zhang, Grail founder join forces on new gene editing startup, Moonwalk

STAT

A new startup co-founded by CRISPR innovator Feng Zhang, a former executive at Grail and Illumina, and others has raised $57 million to develop a defanged form of gene editing that doesn’t cut the DNA strand. Moonwalk Therapeutics launched Thursday with funding from Alpha Wave Ventures, ARCH Venture Partners, Future Ventures, Khosla Ventures, GV, and YK Bioventures.

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Study finds no link between Novo Nordisk’s GLP-1 drugs and suicidal ideation

Fierce Pharma

Three days after the FDA included Novo Nordisk’s semaglutide treatments Ozempic and Wegovy on a list of medicines that it would monitor for side effects—one of them suicide ideation—a study of medi | Three days after the FDA included Novo Nordisk’s semaglutide treatments Ozempic and Wegovy on a list of medicines that it would monitor for side effects—one of them suicide ideation—a study of medical records of patients shows no link between use of the GLP-1 drugs and an increase in suicidal though

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FDA Approval Makes Florida First State to Import Drugs From Canada

Drug Topics

By importing drugs in bulk from Canada, Florida aims to relieve the financial strain faced by patients who struggle to afford necessary medications.

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Study: Bundled Payments for Care Improvement Not Associated With Improved Quality Performance, Outcomes

Pharmacy Times

In-hospital mortality and the Medicare Bundled Payments for Care Improvement (BPCI) model are not associated with changes in odds for Black individuals or female individuals.

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Allen Institute CEO Rui Costa on mapping the brain and paying early-career scientists decent salaries

STAT

Mapping the billions of cells that make up the brain is a task mammoth enough to keep hundreds of researchers across continents busy for years. But it’s just one of several ambitious projects the Allen Institute is helping tackle. The nonprofit research institute, based in Seattle, was founded in 2003 by Microsoft co-founder and philanthropist Paul Allen to go after big and basic scientific questions.

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Hospital, payer price transparency compliance improves, but new requirements are kicking in this year

Fierce Healthcare

A “pivotal year for price transparency” closed out with most—but not all—of the healthcare industry publishing their data publicly and at a higher quality, price transparency data startup Turquoise | A state-of-the-industry report released Thursday found steady improvements in the number of organizations releasing price data, as well as the comprehensiveness and usability of those data.

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MHRA’s post-Brexit mutual recognition framework goes live

pharmaphorum

The UK medicines regulator has launched its mutual recognition framework for authorising medicines in a move that it says will help to bring new drugs to patients in the UK more quickly.

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Study: Machine Learning Can Predict Early Alzheimer Disease, But Has Racial, Ethnic Unfairness

Pharmacy Times

Although machine learning models demonstrate potential to improve early detection of Alzheimer disease, sample sizes that underrepresent ethnic and racial groups result in unfairness.

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Cardiac psychologists are pushing to protect heart patients’ often-overlooked mental health

STAT

Margery Quackenbush was attending a board meeting of the nonprofit where she served as executive director when she felt a sharp, stabbing pain in her chest. As the organization’s president yelled at a board member, Quackenbush — then age 69 — noticed her heart tightening and felt terrified. After that day more than 15 years ago, her cardiologist began a series of tests.

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Novo Nordisk, Eli Lilly's obesity drugs will lead in new drug sales in 2024: Evaluate

Fierce Pharma

Booming demand for blood sugar-modulating diabetes and obesity drugs became the top trend in the biopharma industry in 2023, with two companies—Novo Nordisk and Eli Lilly—overwhelming the market wi | Booming demand for blood sugar-modulating diabetes and obesity drugs became the top trend in the biopharma industry in 2023, with two companies—Novo Nordisk and Eli Lilly—overwhelming the market with their dominance.

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A look back at 2023: A Benchling biotech breakfast

pharmaphorum

Explore the highlights of the 2023 Benchling biotech press roundtable before Benchtalk London, showcasing cutting-edge software and innovations in the field of biotechnology.

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