Sat.Jan 27, 2024 - Fri.Feb 02, 2024

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Pharmacists' Patient Counseling Role

Pharmacy Times

Kristen Peterson, PharmD, BCOP, explores how pharmacists deliver comprehensive education, empower patients, manage side effects, and prioritize outcomes for multiple myeloma care, ensuring quality treatment understanding and adherence.

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COVID-19 Perceived as Less Serious Than Other Respiratory Illness Despite Global Spotlight

Drug Topics

Study findings that identified non-COVID respiratory illness as the most serious health issue among members of low- and middle-income countries provide policymakers with a valuable lens through which to understand and address public health concerns.

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Pharmacists’ Responses in Medical Emergencies Highlight Need for Provider Status

Pharmacy Times

On a flight home from ASHP Midyear in December, one pharmacist stepped up to the plate in a medical emergency.

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Healthcare sector cybersecurity retrospective and the year ahead

pharmaphorum

As cyberattacks continue to target the healthcare sector, it is crucial to look back at cybersecurity incidents from the past year and prepare for the challenges that lie ahead. This retrospective discusses the impact on patients, health systems, insurers, and vendors, and highlights the importance of cybersecurity measures in protecting sensitive healthcare information.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Texas Medical Board under pressure to define emergency exception to abortion ban

STAT

Amid ongoing uncertainty about when abortions are permissible in Texas, the state’s medical board is under growing pressure to issue guidance on what type of emergency qualifies for an exemption from the state’s abortion ban. Two high-profile abortion supporters filed a petition in January requesting the board define what would be grounds for a legal abortion, and their efforts are backed by activists from across the political divide.

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Dexcom Submits New CGM For Non-Insulin Type 2 Diabetes for FDA Clearance

Drug Topics

Although continous glucose monitors (CGMs) have often been tailored to patients with type 1 diabetes, data elicited by these technologies add value to the management of type 2 diabetes by offering insights into patients’ unique responses to food, activity, medications, and more.

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Pfizer's layoff campaign ramps back up with dozens of SF-area cuts expected next month

Fierce Pharma

The start of the new year doesn’t seem to have dulled the zeal of Pfizer’s global cost-cutting campaign, which has already left hundreds of jobs in its wake. | Come mid-February, Pfizer will lay off some 52 employees at a facility in South San Francisco, according to a recent Worker Adjustment and Retraining Notification Act alert. The site is the former headquarters of Global Blood Therapeutics.

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Updated Covid vaccine has 54% effectiveness, new data suggest

STAT

New data released Thursday by the Centers for Disease Control and Prevention suggest that the most recent Covid-19 booster offers about 54% percent protection against infection with the virus. A study published in the CDC’s online journal Morbidity and Mortality Weekly Report showed that the updated vaccine was essentially equally effective at protecting against the strain targeted by the vaccine — called XBB.1.5 — and the JN.1 subvariant, which emerged after the vaccin

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Slideshow: The Role of CGM in Diabetes Management During Pregnancy

Drug Topics

Three posters being presented at the Society for Maternal-Fetal Medicine 44th Annual Pregnancy Meeting examined the impact of continuous glucose monitoring on pregnancy outcomes.

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Recurrent C difficile Infection Prevention: Efficacy and Administration of Fecal Microbiota Therapy

Pharmacy Times

Sharon Rimon, NP, shares insights on the rectal administration of fecal microbiota therapy, highlighting its efficacy, ease of adoption in clinical practice, and benefits for patients.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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FDA sets date for high-profile CAR-T adcomm for Bristol’s Abecma, J&J’s Carvykti

Fierce Pharma

Mark your calendars, oncology drug and CAR-T therapy developers. | Mark your calendars, oncology drug and CAR-T therapy developers. The FDA has decided on a date for a highly anticipated advisory committee meeting for Bristol Myers' Abecma and J&J's Carvykti.

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Some dementia patients might have reversible symptoms caused by cirrhosis, study says

STAT

The descent into dementia can feel like traversing a minefield, coming across new symptoms without the hope of a cure. But some dementia patients, even up to 10% of people diagnosed with the condition, might actually have undiagnosed liver disease and accompanying neurological problems, a new study in JAMA Open Network suggests. Most importantly, it’s possible their liver-related brain symptoms could be resolved with treatment.

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Short Animated Videos on Social Media May Help Increase Knowledge of Vaccines

Drug Topics

Findings from a recent study showed that participants who watched a video discussing COVID-19 vaccination had significantly higher knowledge scores compared to those who did not watch it.

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Researchers Highlight Need for Greater Research Into RSV Among Older Adults, Vaccine Management

Pharmacy Times

The burden of RSV in the older population is becoming highly recognized as studies have assessed higher-risk individuals in industrialized and developing countries.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Biogen abandons Aduhelm efforts, focuses on Eisai-partnered Leqembi and pipeline drugs

Fierce Pharma

More than two years after Aduhelm's controversial and ill-fated FDA accelerated approval, Bi | Biogen is discontinuing its first Alzheimer's disease therapy, Aduhelm, after walking a rocky path. The company is taking a $60 million charge, halting sales and terminating a confirmatory trial.

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FDA urged to move faster to fix pulse oximeters for darker-skinned patients

STAT

The Food and Drug Administration should move more quickly to ensure pulse oximeters — the ubiquitous devices used to measure blood oxygen — work well in all patients, should better inform clinicians about the devices’ shortcomings in patients with darker skin, and should recall versions that are particularly problematic, patients, researchers, and consumer advocates testified during a public meeting on Friday.

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Exploring Non-Pharmacological Interventions in Adolescents With Type 1 Diabetes

Drug Topics

Investigators found that the non-pharmacological interventions were significantly effective at improving HbA1c, quality of life, anxiety, and blood glucose.

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Study: Hydroxyurea Reduces Severe, Invasive Infections by 60% in Children with Sickle Cell Disease

Pharmacy Times

The findings suggest that further research on additional intervention methods and expanding access to hydroxyurea in Africa could benefit young patients with sickle cell disease.

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Insurer survey: No Surprises Act shielded patients from 10M surprise bills

Fierce Healthcare

Patients were protected from more than 10 million surprise medical bills thanks to reforms in the No Surprises Act, according to a new survey. | Patients were protected from more than 10 million surprise medical bills thanks to reforms in the No Surprises Act, according to a new survey.

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Scientists document first-ever transmitted Alzheimer’s cases, tied to no-longer-used medical procedure

STAT

LONDON — There was something odd about these Alzheimer’s cases. Part of it was the patients’ presentations: Some didn’t have the classic symptoms of the condition. But it was also that the patients were in their 40s and 50s, even their 30s, far younger than people who normally develop the disease. They didn’t even have the known genetic mutations that can set people on the course for such early-onset Alzheimer’s.

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Single Dose Typhoid Vaccine Effective in Children

Drug Topics

The vaccine showed an overall efficacy of 80% in the per-protocol analysis, with a risk reduction of 6.1 typhoid infections per 1000 vaccinated children.

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Behavioral Psychotherapy, Antidepressants Yield Minimal Differences in Depression Treatment Coinciding With Heart Failure

Pharmacy Times

Investigators determined the effectiveness of behavioral activation psychotherapy versus antidepressant medication management for inpatients with heart failure and depression.

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WuXi Biologics plays defense after US bill brands certain Chinese biopharmas as security threats

Fierce Pharma

New legislation aimed at blocking a group of Chinese biopharma firms from tapping into U.S. federal funding has sent shares tumbling in recent days. | New legislation aimed at blocking a group of Chinese biopharma firms from tapping into U.S. federal funding has sent shares tumbling in recent days. WuXi Bio, for its part, says it's not affiliated with the military in China.

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Opinion: I’m an anesthesiologist. Kenneth Smith’s execution by nitrogen gas was far from ‘textbook’

STAT

On Thursday evening, the state of Alabama executed Kenneth Eugene Smith by nitrogen gas. Now, there are dueling narratives about what happened. Alabama claims it went perfectly, proving that nitrogen is a humane, effective alternative to lethal injection (which it previously tried, unsuccessfully, to use on Smith). It says that based on this experience, other states should follow its example.

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Diabetes Mortality Trends Remained Steady in the Americas Over 20-Year Period

Drug Topics

Although diabetes mortality rates were stable in the Americas over the past 2 decades, the actual number of diabetes-related deaths is rising.

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Pembrolizumab Improves Disease-Free Survival for Muscle-Invasive Urothelial Carcinoma

Pharmacy Times

The late-breaking data at the 2024 American Society of Clinical Oncology Genitourinary Cancers Symposium included the results of KEYNOTE-123 for locally advanced resectable urothelial carcinoma.

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Merck is on the lookout for more opportunities within immunology

Pharmaceutical Technology

At the JP Morgan Healthcare conference, Merck (MSD) indicated its eagerness to continue to establish its place in the immunological space.

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STAT+: Judge skeptical of arguments against Medicare drug price negotiation

STAT

WILMINGTON, Del. — Wednesday was the first time that a federal judge asked questions in-person of drug industry lawyers who are trying to stop Medicare from negotiating drug prices. It didn’t go well for them. AstraZeneca’s lawyers argued that Medicare’s new powers amount to a taking of their property rights without due process.

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GSK confirms Arexvy is a blockbuster but says the RSV battle has just begun

Fierce Pharma

Beaten to the punch by Pfizer in developing a vaccine for COVID, GSK has regained some of its lost luster as a vaccine powerhouse with its advancement of respiratory syncytial virus (RSV) shot Arex | GSK's RSV vaccine Arexvy generated $1.5 billion in sales in 2023 compared to $890 million for Pfizer's Abrysvo. But the British pharma major says that the successful launch represents just one round of a boxing match, and much is still to be decided, especially with Moderna expected to joi

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Considerations for RSV Prevention in Special Patient Populations

Pharmacy Times

Older adults, patients with weakened immune systems, individuals living in long-term facilities, and those with underlying cardiopulmonary disease are at a higher risk of developing severe RSV infection outcomes.

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Hospital-backed proposal would make insurers reveal prior auth denial rates

Fierce Healthcare

A recommendation on the 2024 Measures Under Consideration list, brought forward by the Federation of American Hospitals (FAH), would add a quality measure in the Medicare Advantage (MA) star rating | The Federation of American Hospitals is pushing CMS for the inclusion of a star ratings quality measure that shows how often insurers overturn or uphold prior authorization denials.

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STAT+: Ultima Genomics launching high-end DNA sequencers that can read genome for $100

STAT

Ultima Genomics, an upstart some observers have called a “ dark horse ” in the world of DNA sequencing, will soon launch a line of high-power instruments that can read a human genome for as little as $100, the company’s leadership told STAT. The sequencer, dubbed the UG 100, is a $1.5 million machine that can read up to 20,000 human genomes a year.

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Who's No. 1? With $25B in sales, Merck's Keytruda looks to be the top-selling drug of 2023

Fierce Pharma

With Merck reporting a whopping $25 billion sales haul for | With Merck reporting a whopping $25 billion sales haul for Keytruda on Thursday, the PD-1 cancer superstar appears to be the world’s top-selling drug in 2023. Keytruda looks set to take over the top spot from Pfizer and BioNTech’s Comirnaty, which ruled the previous two years, scoring sales of $55.9 billion in 2022 and $55.1 billion in 2021.

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Understand the Differences in Carbidopa/Levodopa Formulations for Parkinson Disease

Pharmacy Times

Understanding differences in the various levodopa formulations and assisting with medication therapy management is a crucial role for pharmacists.

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