Sat.Jan 13, 2024 - Fri.Jan 19, 2024

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To Crush or Not to Crush: That is the Medication Administration Question

Pharmacy Times

Pharmacists are well suited to identify patients with dysphagia and educate patients and caregivers on when and how to safely crush and administer medication.

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Community Pharmacists Have Distinct Role in Fall Prevention for Patients

Pharmacy Times

Pharmacists play a significant role in early identification, continuous monitoring, and interventions to help minimize the risk of falls in older adults.

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Navigating A Unique Journey: Dr. Lindsey Moseley’s Inspiring Path in Pharmacy Education

Pharmacy Is Right For Me

A pharmacy education provides diverse opportunities, ranging from patient care and research to education. Truly, no one path looks the same and there is no better example than Dr. Lindsey Moseley who found her passion for teaching and education whilst pursuing her Pharm.D. degree. Facing An Identity Crisis Dr. Lindsey Moseley is the Curricular Coordinator and a faculty member at Auburn University Harrison College of Pharmacy.

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Pharmacy Practice in Focus: Health Systems Launches the Peer-Review Process in 2024

Pharmacy Times

In 2024, Pharmacy Practice in Focus: Health Systems welcomes the launch of the peer-review process, with this issue containing our first peer-reviewed paper.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Vaccine Innovation Continued in 2023 with Several Important Approvals

Drug Topics

In 2023, the FDA approved six vaccines, including 2 for respiratory syncytial virus (RSV), and the first vaccine to prevent the mosquito-borne virus chikungunya.

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STAT+: Dana-Farber cancer researchers moving to retract one paper, correct others in broad investigation of manipulated data

STAT

Scientists at Dana-Farber Cancer Institute, one of the nation’s leading cancer research and treatment centers, are “moving to” retract one paper and correct others amid an expanding investigation of data manipulation, officials told STAT. The investigation includes scores of papers authored by four top scientists and institute leaders, including CEO Laurie Glimcher and COO William Hahn.

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All it Takes is a Conversation: Deprescribing Benzodiazepines in Older Adults

Pharmacy Times

Benzodiazepines have proven effective in managing anxiety and insomnia, but they heighten risk of falls, cognitive impairment, functional decline, and mortality among older adults.

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Florida Drug Importation Program Faces Nationwide Opposition From Pharmacy Organizations

Drug Topics

Just weeks after it gained FDA approval, pharmacy organizations have come forward to voice concerns about the safety and security of Florida’s drug importation program.

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Could long Covid’s signs of immune dysregulation in the blood lead to a diagnostic test?

STAT

Long Covid has long eluded scientists looking for its cause. Not knowing what triggers its persistent and distressing symptoms makes the condition challenging to treat; it’s hard to even say definitively who has it. New research published Thursday in Science has identified proteins present in the blood of people with long Covid that could point the way to a much-needed diagnostic test and possibly to future therapeutic targets.

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General Catalyst's new health system company to acquire Summa Health

Fierce Healthcare

Venture capital firm General Catalyst is making good on its October promise to purchase a health system with about eight months left to spare. | The venture capital firm's deal would make the Ohio nonprofit a wholly owned subsidiary of the recently launched Health Assurance Transformation Corp. The deal still requires regulatory approval.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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PQA Releases Third Edition of Social Determinants of Health Resource Guide

Pharmacy Times

The third edition of the Pharmacy Quality Alliance resource guide includes 40 total SDOH services and 8 new services, as well as 10 initiative updates from the previous 2 editions.

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Pharmacist Interventions May Improve Clinical Outcomes of Patients With T2D

Drug Topics

By getting involved in patient care, pharmacists can help alleviate the burdens associated with the self-management of type 2 diabetes (T2D).

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STAT+: CRISPR-edited pig liver from eGenesis passes first test in brain-dead human, researchers say

STAT

For three days in December, an ICU room at the Hospital of the University of Pennsylvania bore witness to the first-ever merging of two powerful new technologies poised to change the future of transplant medicine. On a gurney, a brain-dead patient lay connected to a whirring Rube Goldberg-esque machine: a tangle of tubes and siphons on wheels. From a cannula on one end, blood from the patient entered, was pumped full of oxygen and other nutrients, then pushed into a cozy, temperature-controlled

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Morgan Health: 3 things employers should focus on to manage GLP-1s

Fierce Healthcare

Demand remains high for GLP-1 drugs, and the experts at Morgan Health are aiming to support employers in managing that interest with a new report. | Demand remains high for GLP-1 drugs, and the experts at Morgan Health are aiming to support employers in managing that interest with a new report.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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FDA Approves IgG-Hyaluronidase Recombinant for the Treatment of Adult Patients With CIDP

Pharmacy Times

Previously, IgG-hyaluronidase recombinant was approved by the FDA in 2014 for the treatment of primary immunodeficiency in adult patients and has expanded to include some pediatric patients.

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COVID-19 Vaccination Not Associated with Increased Postmenopausal Bleeding

Drug Topics

Data has indicated a potential association between COVID-19 vaccination and menstruation, but there is little evidence about this association based on chart-reviewed medical record data.

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Pumping breastmilk in bathrooms is a common, albeit unspoken, practice at health care conferences

STAT

Even though Erin Booth was not thrilled about having to travel to Philadelphia for a conference at six weeks postpartum, this one at least advertised having a private lactation space. This was back in 2013, when such accommodations were a rarity. The first bad sign was having to walk clear across the convention center to get there, cutting into her already brief pumping window.

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13 health systems collaborate with high schools in $250M initiative to boost healthcare workforce

Fierce Healthcare

As the U.S. | The new program from Bloomberg Philanthropies and major systems like Mass General Brigham, HCA Healthcare and Northwell Health will build new or refurbish existing high schools in 10 urban and rural communities.

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No Significant Differences in Efficacy Shown Between Reference Drug, Biosimilars in Patients With IBD

Pharmacy Times

Despite the insignificant differences in efficacy, biomarkers, therapeutic drug level, and ADAs, patients reported a significant number of nocebo effects.

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Real-Time CGM Superior to Intermittently Scanned CGM in T1D, Analysis Finds

Drug Topics

Real-time continuous glucose monitoring (CGM) demonstrated benefits associated with time in range, hypoglycemia, and hyperglycemia in patients with type 1 diabetes (T1D).

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STAT+: The FDA’s diagnostics chief, who led through Covid, has retired

STAT

Timothy Stenzel, the federal regulator who led the Food and Drug Administration’s diagnostics division during the chaotic time of Covid-19 pandemic, has left the agency. The FDA confirmed Thursday that Stenzel, who led the FDA’s office of in vitro diagnostics, retired at the end of 2023.  During the early days of the pandemic, Stenzel was in the middle of a turf battle between the Centers for Disease Control and Prevention and the FDA over the regulation of Covid tests.

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‘Medicine is going personalised’: Moderna’s UK boss on the coming vaccine revolution

The Guardian - Pharmaceutical Industry

Darius Hughes was a key figure in Pfizer’s pioneering Covid vaccine drive. Now he has changed companies – and sees a big future for mRNA technology The man who launched Pfizer’s Covid-19 vaccine in the UK three years ago – when 90-year-old Margaret Keenan in Coventry became the first person in the world to receive one – is now overseeing the construction of a manufacturing and research centre in Oxfordshire for rival US jab maker Moderna.

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Psychedelic Pharmacists Association Is Working to Promote, Establish the Role of the Pharmacist in Psychedelic-Assisted Therapy

Pharmacy Times

The co-founders of PPA discuss the importance of advocacy work at this point in the development of the psychedelic medicine industry to help cement pharmacist’s role in the continuum of care.

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Work Pressure During COVID-19 Pandemic Increased Problematic Substance Use Among First Responders

Drug Topics

Problematic substance use was highest among firefighters, followed by emergency medical technicians, and police officers.

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The WHO and drug regulators want to reformulate the flu vaccine. It’s easier said than done

STAT

Last fall, the World Health Organization and some national drug regulators urged influenza vaccine manufacturers to drop the component known as B/Yamagata from flu vaccines as quickly as possible, citing the fact that this lineage of flu B viruses appears to have been snuffed out during the Covid-19 pandemic. It might seem like that request would be as simple as deciding to leave blueberries out of a mixed-fruit smoothie.

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After row with Hungary and Poland, Pfizer sues Romania over missed COVID vaccine payments

Fierce Pharma

Following public spats with Hungary and Poland, Pfizer and its German mRNA partner BioNTech have kicked off legal proceedings against Romania. | Following public spats with Hungary and Poland, Pfizer and its German mRNA partner BioNTech have kicked off legal proceedings against Romania. The lawsuit marks the latest move in Pfizer’s campaign to press countries to honor COVID-19 vaccine contracts inked by the European Commission in May 2021.

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5 Key Potential Approvals for 2024

Pharmacy Times

Multiple sclerosis and pulmonary arterial hypertension are disease states expected to have new medications in the upcoming year

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COVID-19 Vaccination Effective at Preventing Long COVID in Children, Adolescents

Drug Topics

Within a 12-month time frame, adjusted vaccine effectiveness against diagnosed long and probable long COVID was 41.7% and 35.4%, respectively.

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Feds bar Theranos founder Elizabeth Holmes from government health programs

STAT

WASHINGTON — Theranos founder and ex-CEO Elizabeth Holmes is banned from federal health programs for nine decades, the health department announced Friday. Holmes was sentenced in November 2022 to 11 years in prison following a trial that determined she knew her blood-testing startup, which was founded in 2003 and which claimed to be able to test for a range of diseases and risks with one finger prick, produced inaccurate and faulty results.

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Bristol Myers shows power of Opdivo-Yervoy combo in first-line colorectal cancer subset

Fierce Pharma

More than five years after an FDA accelerated approval in a subtype of progressive colorectal cancer, Bristol Myers Squibb now has data supporting its checkpoint inhibitor doublet in newly diagnose | More than five years after an FDA accelerated approval in a subtype of progressive colorectal cancer, Bristol Myers Squibb now has data supporting its checkpoint inhibitor doublet in newly diagnosed patients.

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Analysis Indicates Daily Multivitamin Benefits Global Cognition, Episodic Memory in Adults

Pharmacy Times

Compared to placebo, a daily multivitamin showed consistent benefits in global cognition and episodic memory across a clinical trial and meta-analysis of 3 trials.

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RSV: Clinicians Discuss Strategies to Deal with Vaccine Resistance

Drug Topics

A panel of clinicians gathered to address concerns and report preliminary findings around rates of RSV incidence, hospitalization, and vaccination.

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STAT+: FDA expands approval of CRISPR-based medicine to treat beta thalassemia

STAT

The Food and Drug Administration on Tuesday approved a CRISPR-based medicine to treat beta thalassemia, an inherited blood disorder. It’s the same potentially curative therapy cleared by the FDA in December to treat sickle cell disease. The expanded approval of the therapy, called Casgevy, was widely expected but came two months ahead of the FDA’s decision deadline, known as a PDUFA date.

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Innovaccer acquires customer engagement platform Cured to enhance patient experience

Fierce Healthcare

Innovaccer, maker of digital tools for providers, has acquired Cured, a digital marketing and customer relationship management [CRM] platform. | The strategic purchase adds more than 20 health systems and first-time digital health clients to Innovaccer’s current portfolio of customers.

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