Sat.Jan 02, 2021 - Fri.Jan 08, 2021

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FDA and doctors warn against extending COVID-19 vaccine dose gap

pharmaphorum

Tinkering with the dosing schedule of COVID-19 vaccines runs a “significant risk” to public health, the FDA has warned in a statement after the UK announced plans to prioritise the first doses of two approved shots. The regulator made its comments after the UK announced a policy of stretching the gap between doses of the vaccine to up to 12 weeks to ensure maximum coverage of vulnerable groups.

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Flucloxacillin vs Amoxicillin: 2 most POPULAR antibiotics

Druggist

Amoxicillin is the most commonly prescribed antibiotic in the UK, with over 6 mln prescriptions issued in the last 12 months. Flucloxacillin is less popular with around 3.6 mln prescriptions issued during the same time (OpenPrescribing.net, 2021). Both antibiotics’ distinct popularity comes mainly from different recommended use in the treatment of bacterial infections, even though both drugs belong to the same class of antibiotics: penicillins.

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People on the Move: January 2021

Outsourcing Pharma

Industry organizations with hires, promotions, acquisitions and other news to share this month include Parexel, Novartis, WCG, Idifarma and more top firms.

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CRUK scientists develop drug that targets KRAS pathways

Pharma Times

KRAS mutations are found in several hard-to-treat cancers

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Pfizer/BioNTech vaccine may work against new virus mutation, scientists say

pharmaphorum

The Pfizer/BioNTech vaccine appears to work against an important mutation in the new coronavirus variants causing havoc in the UK and South Africa, according to research from the drugs giant. Findings of the lab study posted online have not yet been peer reviewed but provide some reassurance for countries like the UK, which are relying on vaccines to bring the pandemic under control.

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Choosing a Baby Formula

Pharma Mirror

Infant nutrition, outside of breastfeeding, has become a hot topic recently. Families are taking a hard look at how baby formulas’ ingredients impact their children’s health and development. Concerns and Contamination Every day American parents and caregivers reach for over-the-counter baby formulas and are surprised to find chemicals, additives, and other ingredients that are known to cause health concerns.

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More Trending

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Janssen files EGFR-targeting antibody amivantamab with EMA

Pharma Times

Submission based on results from phase I CHRYSALIS study

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Why cell therapy manufacture is a team sport

pharmaphorum

Louis van de Wiel, Vice President, Site Head EU Manufacturing, Kite, a Gilead Company, reveals the complexity that sits behind the process of individualised cell therapy – and why team culture makes it work. This thought leadership series has been paid and developed by Kite, a Gilead Company. In 2018, we were preparing to build a European facility to produce individualised cell therapies for the treatment of cancer.

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Why We Would and Wouldn’t Use Ziprasidone

Med Ed 101

Looking at the adverse effect profile of second-generation antipsychotics is critical to medication selection in clinical practice. You should definitely know the general list of adverse effects of antipsychotics (i.e. EPS, metabolic syndrome, QTc prolongation, etc.). What you should also be aware of is the subtleties for each individual agent. For ziprasidone, I remember two […].

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Opportunities abound with ‘rescue’ studies: Bioclinica

Outsourcing Pharma

An executive with the clinical research tech firm explains that while such studies can be rife with problems, the right approach can yield results.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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EMA launches review of BMS’ Opdivo for oesophageal cancer

Pharma Times

Company is aiming for approval in the adjuvant setting

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How Big Data will accelerate the future of digital medicine in 2021

pharmaphorum

The pandemic has shed light on inefficiencies in healthcare systems, and provided an opportunity to adjust how we manage care in the future. Jennifer Haas, executive vice president of Noteworth, shares her 2021 predictions surrounding the future of telehealth and big data. . Healthcare providers are grappling with the task of scaling digital care delivery operations for ambulatory patients in response to the cost dynamics of effectively treating large populations with limited resources, especial

Hospitals 111
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GLP-1 Agonists And The Prescribing Cascade

Med Ed 101

The GLP-1 Agonists have grown significantly in their popularity and there are good reasons for that increase in use. They promote weight loss which is a big problem in the majority of our type 2 diabetes patients. In addition to this benefit, they have also been shown to positively affect cardiovascular outcomes. With any medication, […]. The post GLP-1 Agonists And The Prescribing Cascade appeared first on Med Ed 101.

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Phesi, Sensyne Health partner on synthetic arm tech for trials

Outsourcing Pharma

The two organizations will collaborate on development of synthetic arms for clinical studies, drawing from millions of patient records and trial subject.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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NICE collaboration creates new route for medicines approval

Pharma Times

New Innovative Licensing and Access Pathway launched

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Oxford BioTherapeutics to research cell therapies for Gilead’s Kite

pharmaphorum

Gilead Sciences’ Kite unit has teamed up with the UK’s Oxford BioTherapeutics (OBT) to develop a new clutch of cell therapy products for solid tumours and blood cancers. The partnership covers up to five oncology targets identified by OBT using its discovery platform, and the UK firm will try to develop antibodies against them. Kite and Gilead will then develop and commercialise therapies based on these targets or antibodies.

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5 Trends That Will Shape Pharma Marketing in 2021

Pharma Marketing Network

Throughout the year 2020, pharma marketers were forced to explore new strategies in order to keep up with the many evolving trends. Pharma marketers have quickly learned how to adapt to these trends and are prepared to take on new opportunities in 2021. Five trends that will shape the pharma marketing industry in 2021 include media and tech, location independence, relationships despite digital congestion, questioning systems and doubt in institutions, and feelings around trust and wellness.

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Syneos Health acquires Illingworth Research Group

Outsourcing Pharma

The pharma services and solutions firm has purchased the clinical research home health company to support increasing demand for in-home trials.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pfizer’s Lorbrena scores US priority review

Pharma Times

Drug is being reviewed for ALK-positive lung cancer

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True patient-focused research through decentralised and hybrid trials

pharmaphorum

How can pharma improve the patient-centricity of its trials during COVID-19 and beyond? Experts from across the sector give their thoughts on the key approaches and technologies that are driving patient engagement forward. With COVID-19 presenting new barriers to running and recruiting for clinical trials, making studies patient-centric is more important now than ever before.

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How to Find Cheap Vets Near Me

That Frugal Pharmacist

The last thing you ever want to be worrying about is, “where do I find cheap vets near me.” Whether it’s for routine preventative care like wellness checks, vaccinations, spay-neuter, or emergencies and surgeries, everyone wants access to the best low-cost veterinary care they can get for their companion-animal.

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Ampio trials explore potential COVID-19 treatment

Outsourcing Pharma

The immunology-focused company has launched clinical research exploring the potential of its Ampion drug to treat the virus behind the pandemic.

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University of Birmingham researchers develop rapid COVID-19 RNA test

Pharma Times

Test can give accurate results in under five minutes, according to researchers

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EMA will use Panalgo software for real-world data analytics

pharmaphorum

Six months after rebranding from BHE, Panalgo has won a contract to supply the European Medicines Agency (EMA) with its IHD data analytics platform, pledging to streamline its public health efforts. IHD – or Instant Health Data – will be used by the EMA to carry out data analyses and examine medicinal product utilisation, answer questions about safety and efficacy, and understand how treatments perform in real-world settings, said the Boston, US-based company.

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Bayer joins the COVID-19 vaccine push, backing CureVac shot

pharmaphorum

Shortly after launching large-scale trials of its COVID-19 vaccine candidate, CureVac has the partner it will need to roll the shot out at scale if it works as hoped. Bayer has joined forces with the German biotech to support the development and supply of CVnCoV, an mRNA candidate using a similar technology to the Pfizer/BioNTech and Moderna jabs, with the drugmaker saying it will help CureVac produce “several hundred million doses” CureVac has been working steadily on CVnCoV over the last

Vaccines 105
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COVID-19 and the digital pharma marketing revolution

pharmaphorum

The global pandemic has caused pharma companies to invest in digital marketing, as healthcare systems across the world adapt to strict lockdown rules. Once the global emergency ends, this trend will continue, argues pharmaphorum’s Richard Staines. The global outbreak of COVID-19 has forced businesses to radically change their way of working. Healthcare companies have been in the vanguard of this change, with an enormous rise in the use of telehealth and all forms of digital communications.

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AbbVie scores crucial phase 3 wins with Humira follow-up Skyrizi

pharmaphorum

AbbVie is in a race against time as US patent expiry of its Humira inflammatory diseases blockbuster looms in 2023 – but it just scored two crucial phase 3 trial victories that could help rebuild sales when cheaper biosimilars flood the market in two years’ time. The company’s follow-up drug Skyrizi is a key plank in AbbVie’s strategy to negotiate the $20 billion patent cliff from Humira, which has already seen sales decline outside of the US where it has already lost protection from cheaper com

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Using Define-XML for Dataset Design

pharmaphorum

In the past, sponsors submitting to FDA were required to submit a PDF describing their submission datasets. As we all know PDF is great for viewing on-screen or printing, but the information inside can’t be interpreted by a computer. Enter CDISC’s Define-XML model. Define-XML standardizes how to describe datasets in a machine-readable manner.

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Roche set to file ophthalmology drug faricimab in DME

pharmaphorum

Roche looks set to mount a challenge to Bayer’s ophthalmology drug Eylea in 2021 after its faricimab antibody showed comparable results in diabetic macular oedema (DME) but with half the injections, in twin phase 3 studies. While Eylea (aflibercept) is taken in doses eight weeks apart, results from the YOSEMITE and RHINE studies showed faricimab produces a similar effect but with a 16-week dosing regimen.

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Ex-Resolute co-founder Blackburn starts hybrid agency Certain Health

pharmaphorum

Former joint founder and owner of Resolute Communications and Real Science Paul Blackburn has launched a new hybrid agency, Certain Health. Blackburn made the move after Resolute and Real Science were absorbed into Publicis Langland. The company said its hybrid model has the benefits of both the traditional and virtual agency models, with expertise in health PR, medical education and the creative space.

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2021 Outlook: The future for life sciences customer experience

pharmaphorum

Research from a large-scale survey of 1000+ senior pharma professionals has highlighted the divide between digitally adept companies and those that have been slow to adopt technologies. We look at how the customer experience is changing due to COVID-19. Historically, pharma has lagged behind other industries in adopting digital solutions, but with COVID-19 catapulting the sector, and healthcare in general, into a new digital era, the landscape is changing significantly and rapidly.

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Clene goes public with gold-based neurology nanotechnology

pharmaphorum

Biotech Clene Nanomedicine has gone public with a mission to use nanotherapeutics that will use gold to treat devastating neurological diseases including Parkinson’s disease. Over the Christmas period Clene closed a reverse merger with Tottenham Acquisition I Limited, allowing shares to be publicly traded on the Nasdaq stock exchange. The US-based company says it aims to revolutionise treatment of diseases including multiple sclerosis and amyotrophic lateral sclerosis with a new class of drugs t

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Amazon’s health venture Haven to cease trading

pharmaphorum

Haven, the healthcare venture launched by Amazon, Berkshire Hathaway and JP Morgan Chase is to cease trading next month after failing to achieve its goal of pushing down health insurance costs for US workers. The joint venture had been billed by many as Amazon’s big move into healthcare when it was launched three years ago with great fanfare. But since then there has been little news from the secretive venture sparked by an idea from JPMorgan CEO Jamie Dillion, with support from Amazon’s Jeff Be