December, 2024

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It’s Time to Staunch Our Self-Inflicted Wounds

Drug Topics

Outside forces are at play, but pharmacists must turn inward to address some challenges in their profession.

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Opinion: The DEA’s 2025 quotas for opioids will leave seriously ill patients in pain

STAT

A woman sat in our emergency department in agonizing pain, feeling shaky, nauseous, and weak — drug withdrawal was setting in. But she wasn’t a “junkie” or even a recreational drug user. She was in her mid-60s with advanced cancer in her ovaries that had spread to her abdomen, causing unbearable pain. She was my patient — let’s call her Teresa.

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If Zyrtec doesn’t work what should I try?

The Checkup by Singlecare

Zyrtec ( cetirizine ) is an over-the-counter ( OTC ) medication and antihistamine used to treat allergy symptoms. Signs of allergic rhinitis, hay fever , and seasonal allergies include sneezing , runny nose , stuffy nose , swollen nasal passages , itchy eyes , and watery eyes. These conditions are similar to nonallergic rhinitis in that they cause the same symptoms, but they are different in that the latter isnt caused by contact with an allergen.

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A biotech’s race to tackle the most severe hepatitis

PharmaVoice

Bluejay Therapeutics is one of just a handful of companies developing treatments for hepatitis D.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Nanoparticle drug delivery innovation could enhance drug development

European Pharmaceutical Review

Researchers in Australia have created an innovative drug delivery system that utilises a metalbiomolecule network (MBN) comprising of non-toxic metal ions together with phosphonate biomolecules, eg, DNA. As the MBN nanoparticles do not require complicated drug carriers and the materials are bio-compatible, the system has potential to boost successful drug development, according to first author Dr Wanjun Xu.

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Don’t Ignore Erectile Dysfunction

Compounding Pharmacy of America

Erectile dysfunction (ED) is often misunderstood as simply a sexual health concern, but it can signify much more. While many men experience occasional difficulties with sexual performance, persistent ED can be an early warning sign of serious underlying health issues such as cardiovascular disease, diabetes, or hormonal imbalances. Addressing ED is not just about improving […] The post Dont Ignore Erectile Dysfunction appeared first on Compounding Pharmacy of America.

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‘I want help’: Behind bars, pleas for addiction medications often go nowhere

STAT

James Mannion knew what he needed. For nine months, while incarcerated in a county jail in Portland, Maine, he pleaded for a medication called buprenorphine. Mannion, a barber, recreational fisherman, and father of two, was once a regular heroin user, but had used the medication to eliminate the cravings and withdrawal he experienced whenever he tried to quit opioids cold turkey.

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Does Mounjaro need to be refrigerated?

The Checkup by Singlecare

Like semaglutide, Mounjaro (tirzepatide) is a once-a-week injectable medication that is FDA approved for helping manage blood sugar levels in those with Type 2 diabetes. It mimics two gastrointestinal hormones: glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). So, the active ingredient can also be prescribed for weight loss or obesity, combined with diet and exercise, under its licensed brand name Zepbound.

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With Makary set to face FDA commissioner hearings, how deep do his industry ties run?

PharmaVoice

Dr. Marty Makary’s conflicts of interest could come into question before he is confirmed as the next FDA commissioner.

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FDA reaffirms decision to erase Eli Lilly's tirzepatide from shortage list, halting future flow of knockoffs

Fierce Pharma

The FDA has doubled down on its decision to remove Eli Lillys tirzepatide from its list of products that are in shortage. | The FDA has doubled down on its decision to remove Eli Lillys tirzepatide from its list of products that are in shortage. The agencys move means that compounding pharmacies will have to halt production of their knockoff versions of diabetes drug Mounjaro and obesity treatment Zepbound.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Five Lessons Learned About Antimicrobial Stewardship Metrics

IDStewardship

In this article an experienced antimicrobial stewardship pharmacist discusses lessons learned from navigating antimicrobial stewardship metrics. Authored by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article posted 13 December 2024 If you cannot measure it, you cannot determine if you have changedit. Antimicrobial stewardship metrics are essential for identifying, acting on, and re-evaluating opportunities to enhance the safe and appropriateuse of antibiotics.

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PBM Reform Pulled Back in Late Change to Spending Package

Drug Topics

With pressure from the House GOP, expected PBM reform was not included in Congress end-of-year spending package.

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Opinion: Extending Medicare coverage to obesity medications is imperative

STAT

Although bipartisan legislation to provide Medicare coverage for obesity treatments has circulated in Congress for more than a decade, the Congressional Budget Office (CBO) ventured to  estimate  the budgetary effects of such a policy for older Americans starting in 2026 for the very first time in a report published in October.  The CBO should be commended for conducting this comprehensive analysis.

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FDA issues warnings to GLP-1 compounders

The Checkup by Singlecare

Originally approved to help people with Type 2 diabetes, the class of medications known as GLP-1 agonists and dual GIP/GLP-1s quickly acquired a reputation for helping people shed stubborn pounds. As a result, the use of medications like Ozempic , Wegovy , Zepbound , Rybelsus , and Mounjaro has skyrocketed, as people turned to these medications to help them lose weightcausing drug shortages and creating a market for compounded versions of these brand-name drugs.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Will the ‘anti-woke’ movement derail DEI efforts in pharma?

PharmaVoice

Amid the DEI backlash in corporate America, pharma leaders are quietly adjusting tactics.

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2025 BCMTMS Exam – How To Prepare?

Med Ed 101

I’ve put together an approximately 20-minute video on the BCMTMS exam and what you can expect for 2025. General information on the 2025 BCMTMS Exam Who writes the exam? – National Board of Medication Therapy Management Eligibility ASK EMPLOYER IF THEY WILL HELP PURCHASE STUDY MATERIALS AND TEST COSTS!!!! About The BCMTMS Exam Content Domains […] The post 2025 BCMTMS Exam – How To Prepare?

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‘Wild west’: experts concerned by illegal promotion of weight-loss jabs in UK

The Guardian - Pharmaceutical Industry

Guardian review finds many online pharmacies flouting strict advertising rules that govern prescription-only drugs Weight-loss injections are being aggressively marketed to British consumers through often illegal promotions, in a practice experts have described as a wild west industry of drug selling. The booming market for jabs such as Wegovy and Mounjaro has triggered a price battle among online pharmacies, with even high-street chains cashing in on the soaring demand.

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Younger, Middle-Aged Adults Face Higher Burden of Neurologic Long COVID Symptoms

Drug Topics

The higher burden of neurological symptoms among younger and middle-aged adults translated to worse subjective quality of life, according to a recent study.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Next-gen obesity treatment from Novo Nordisk misses mark in pivotal trial

STAT

Novo Nordisk’s next-generation obesity candidate led patients to lose a substantial amount of weight in a pivotal study but fell short of expectations, results that cast into doubt the future competitiveness of the company in the booming weight loss market. The treatment, called CagriSema, led patients to lose 20% of their weight at 68 weeks in a late-stage study when looking at all participants, including those who dropped out, Novo said Friday.

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What to know about Linzess and coffee

The Checkup by Singlecare

Tens of millions of people start their day with coffee without a second thoughtmany even find it difficult to have any thoughts at all before their first cup. But if youre taking prescription drugs on a regular basis, such as Linzess (the brand name for linaclotide), you may be wondering if you need to rethink your morning joe. Linzess is an oral medication that is approved by the Food and Drug Administration for the treatment of irritable bowel syndrome with constipation (IBS-C) as well as chro

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Merck’s RSV antibody could soon paddle into the rough waters of a crowded market

PharmaVoice

A new antibody from Merck would join a market teeming with new entries, but plenty of regulatory and financial uncertainty.

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Sanofi charts biggest China investment to date with plans for €1B insulin 'manufacturing base' in Beijing

Fierce Pharma

Shortly after a similarly sized venture from Pfizer, French pharma juggernaut Sanofi has unveiled a major manufacturing outlay in China, marking its biggest investment in the country to date. | Sanofi is laying out roughly 1 billion euros ($1.04 billion) to establish a new production base in the Beijing Economic and Technological Development Zone. The new manufacturing site, which will become Sanofi’s fourth in China, is being designed to beef up local end-to-end insulin production.

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‘It’s absolutely open to abuse’: web awash with weight-loss drug offers

The Guardian - Pharmaceutical Industry

Readers describe aggressive online promotions, Black Friday deals and special offers for prescription-only drugs After Andy King was told he was not eligible to receive weight-loss jabs on the NHS, he turned to the internet to order them privately. But before long, he was inundated with promotions. Every other advert on my social media feed is an offer to have a Black Friday deal on the drugs, he said.

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Cannabis Could Help Reduce Opioid Use in Patients with Chronic Pain

Drug Topics

Most patients with reduced opioid prescriptions during cannabis use had chronic musculoskeletal pain.

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STAT+: Health plan formularies lowered barriers to fair access to some drugs, analysis finds

STAT

Most of the formularies run by some of the largest health plans in the U.S. generally provide “fair access” to 11 treatments for several serious diseases, although transparent coverage information is often lacking for some medicines, a new analysis has found. Almost uniformly, the 11 formularies made the drugs available fairly when judged on three criteria: eligibility based on clinical data, restrictions placed on prescribers, and step therapy, which requires patients to try other

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Can you eat oranges if you have diabetes?

The Checkup by Singlecare

Theres nothing like biting into a sun-kissed orange, its juice filling your mouth with the refreshing taste of citrus. But if youre a person living with diabetes , you may wonder what effect the sweet treat will have on your blood sugar. You probably know that managing your blood sugar levels means being mindful of your carbohydrate intake and the glycemic index of your foods.

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Milk-based therapies could be coming. This biotech CEO is aiming to lead the way.

PharmaVoice

Intrinsic Medicines is entering phase 2 trials in Parkinson’s disease and IBS for its human milk oligosaccharide drug candidates next year.

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Merry Christmas!

OctariusRx

Merry Christmas! Thank you to our clients, family, and friends for all your support this year. Our entire team is grateful for our blessings and the wonderful people we work with. Whether you joined us this December, or have been with us for many years, thank you for allowing us to take care of you. We appreciate your trust and support. A successful year would be impossible without our hardworking team.

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Shrinking waistlines and growing profits: the weight-loss drug boom

The Guardian - Pharmaceutical Industry

Drugs such as Wegovy amd Mounjaro are an attractive prospect for online businesses and traditional pharmacies as well as the firms that make them It is a trend rooted in profit-making. Adverts featuring prescription-only weight-loss medications are splashed across the internet and it is causing concern among experts. But the question remains: who is driving the boom?

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Phase 3 Trial to Evaluate Molnupiravir for Treatment of COVID-19 in High-Risk Adults

Drug Topics

The MOVe-NOW study will assess the investigational oral antiviral using a different formulation than what is currently approved under an emergency use authorization.

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STAT+: Eli Lilly to test obesity medications as treatments for alcohol and drug addiction, CEO says

STAT

Eli Lilly, the company that makes the blockbuster weight loss treatment Zepbound, will start studying its obesity products as treatments for alcohol and drug abuse, making it the first major drugmaker to do so, CEO David Ricks said Tuesday. Emerging research suggests that GLP-1 drugs — Zepbound is one such treatment — not only reduce food cravings but may also suppress desires for other substances.

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Does amlodipine lower heart rate?

The Checkup by Singlecare

Sold under brand names such as Amvaz, Katerzia, Norliqva, and Norvasc , amlodipine is a medication that is FDA approved for the treatment of hypertension (high blood pressure), chronic stable angina (chest pain and pressure), vasospastic angina (coronary artery spasm), and coronary artery disease. It belongs to a class of medications called calcium channel blockers, which is further broken down into two classes: dihydropyridine calcium channel blockers and nondihydropyridine calcium channel bloc

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Big Pharma’s new DTC play: partnering with digital health providers

PharmaVoice

The pharma giant is looking for another edge in the competitive weight loss market through DTC expansion.

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