Thu.May 01, 2025

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IRA Drug Price Negotiations to Have Far-Reaching Consequences on Health Care System | Asembia 2025

Drug Topics

The Inflation Reduction Act's drug price negotiations could lead to reimbursement complexities, potential pharmacy closures, and reduced patient access to medications, particularly specialty drugs.

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Sedative ‘dex’ is replacing ‘tranq’ in illegal drug supply and causing excruciating withdrawal

STAT

The era of “tranq” may be ending. But tranq, as the powerful veterinary tranquilizer xylazine is known in the illicit drug supply, is being replaced at least in part by a dangerous new sedative: medetomidine. In the past year, the anesthetic has become an increasingly common element in the drug supply, with cities and states including Philadelphia, Pittsburgh, Chicago, and San Francisco reporting cases of medetomidine-involved overdoses.

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STIs Pose Significant Threat to Fertility, Global Women’s Health

Drug Topics

In the researchers review of data since 1990, they explored the global burden of infertility and the extent in which it is caused by either STIs or maternal sepsis.

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STAT+: CVS Health’s Aetna to abandon Affordable Care Act insurance marketplaces, again

STAT

CVS Health will not sell its Aetna health plans in the Affordable Care Act’s individual marketplaces in 2026, marking the second time in the past decade that Aetna has given up on ACA coverage. CVS expects to lose up to $400 million this year in its ACA plans. The conglomerate set aside $448 million in the first quarter to cover medical claims from ACA members that won’t be covered by insurance premiums.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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AI, Automation Can Help Reshape Pharmacy Patient Care | Asembia 2025

Drug Topics

A conversation with Sarah Thomas and David Skomo of HealthDyne at Asembias AXS25 Summit.

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STAT+: Eli Lilly shares fall as competitor Novo notches coverage win for obesity drug

STAT

Shares of Eli Lilly dropped in pre-market trading Thursday, as competitor Novo Nordisk secured a major win on insurance coverage of its obesity drug and as Lilly reported first-quarter earnings that fell short of what investors wanted to see. CVS Caremark, the largest pharmacy benefit manager in the U.S., announced Thursday that starting in July, Novo’s weight loss treatment Wegovy will be the preferred GLP-1 medicine on its largest commercial formularies, likely making Wegovy more access

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Opinion: RFK Jr.’s synthetic dye bans miss a much bigger problem

STAT

As a professor of physiology, I study how scientific evidence gets translated, sometimes clumsily, from the lab to real life. Whether it’s scaling dietary supplements to humans or using biomimicry to mitigate sports concussion , my work often centers on the fine line between meaningful evidence and misleading extrapolation. That’s why I was immediately skeptical when the Food and Drug Administration announced its decision to ban synthetic food dyes like the controversial red dye No

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Projection Estimates GLP-1 Market to Nearly Double by End of Decade | Asembia 2025

Drug Topics

Although the market is expected to continue to become more popular, compounding pharmacies will no longer be allowed to manufacture these medications, as shortages have been listed as resolved.

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STAT+: Pharmalittle: We’re reading about a WHO plan to back obesity drugs, a big win for Novo Nordisk, and more

STAT

Top of the morning to you, and a fine one it is. Clear blue skies and pleasant breezes are wafting across the Pharmalot campus, where the official mascots are foraging for their breakfast and rousing the neighbors. This means we are free to focus on the matters at hand — rummaging through our to-do list and making cups of stimulation. Our choice today is lavender vanilla.

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The Normalization of Lifestyle Drugs on Social Media

Drug Topics

Amid record levels of advertisements for lifestyle medications on social media, Luke Turnock, PhD, discusses the global impact these trends may have on patients.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Opinion: Why NIH’s policy on grants to universities with DEI programs is not cause for widespread alarm

STAT

The recent news that the NIH will require universities to certify their diversity programs comply with federal civil rights law created understandable anxiety in the academic community. The confusion is partly due to coverage that suggested NIH is terminating support for any universities that operate diversity, equity, and inclusion (DEI) programs. But reading the actual NIH notice carefully provides clarity — and perhaps some reassurance.

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New analysis: Fewer treatments and cures under the IRA’s pill penalty

PhRMA

Patients in the U.S. will soon be left with fewer new, affordable and convenient treatments, if Congress fails to fix a harmful provision in the Inflation Reduction Act (IRA) referred to as the “pill penalty.

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STAT+: M&A is back, but nothing in biotech is neat or simple

STAT

This story first appeared in Adam’s Biotech Scorecard, a subscriber-only newsletter. STAT+ subscribers can sign up  here  to get it delivered to their inbox. Biotech mood check: Happy Two acquisitions. Strong drug launches. FDA drug approvals. A rebounding XBI now 18% higher from its recent low.  All in, a very pleasant week so far.

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When hospitals have free rein to mark up drug prices, who pays the price?

PhRMA

The 340B hospital markup program continues to skyrocket every year. Yet there is little to no evidence that this immense growth is benefiting the uninsured and low-income patients that the program was designed to serve. If the money isn’t going to help patients, where is it going?

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Clinical pharmacy leadership: a view from Scotland

Hospital Pharmacy Europe

As the NHS advances, effective clinical leadership in pharmacy is vital to improve the pharmaceutical care of patients. In Scotland, the Scottish Pharmacy Clinical Leadership Fellowship scheme aims to support just that, as Gerry Hughes finds out. The goal of the Scottish Pharmacy Clinical Leadership Fellowship , launched in 2018, is to nurture future pharmacy leaders and advance strategic healthcare goals in Scotland.

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Can real-world evidence bear some of the burden left by NIH cuts? This CEO sees an opportunity.

PharmaVoice

Turmoil at the NIH has led to handwringing among researchers and drugmakers who rely on public funding.

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Real-world impact of medication adherence in pulmonary hypertension identified

Hospital Pharmacy Europe

Consistent adherence to pulmonary hypertension-specific oral therapy significantly improves clinical outcomes, according to a new prospective study evaluating patients with pulmonary arterial hypertension (PAH) and distal chronic thromboembolic pulmonary hypertension (CTEPH). These two conditions are progressive, life-limiting diseases where timely, consistent medication use is critical to stabilise symptoms and prolong survival.

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FDA Approves Atzumi, Nasal Powder Formulation of DHE, for Acute Treatment of Migraine

Pharmacy Times

In clinical trials, the dihydroergotamine (DHE) nasal powder had favorable safety profiles and rapid pain relief in patients with migraine with or without aura.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Prednisone for poison ivy: Effectiveness, dosing, and how it works

The Checkup by Singlecare

Prednisone is a type of medication called an oral corticosteroid. Its used to treat inflammation in the body, from conditions like allergies, asthma, arthritis, blood disorders, cancer, autoimmune diseases, and various skin conditions. Prednisone can also be used to calm an overactive immune system. If you are dealing with an itchy, uncomfortable case of poison ivy , you might be wondering if you can use prednisone for poison ivy.

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Neogap chosen for Innovate Nordics 2025 Acceleration Programme

Pharmafile

Swedish biotech company Neogap Therapeutics has been chosen to join Innovate Nordics 2025 acceleration programme, a prestigious initiative designed to help Nordic growth companies expand into the US market. Organised by the Swedish-American Chamber of Commerce in New York (SACCNY) in partnership with EY, the programme provides selected companies with access to US investor networks, […] The post Neogap chosen for Innovate Nordics 2025 Acceleration Programme appeared first on Pharmafile.

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Updates in the Management of Transplant-Ineligible Patients With Multiple Myeloma

Pharmacy Times

Explore the latest advancements in treating transplant-ineligible multiple myeloma, highlighting new therapies and clinical trial outcomes for improved patient care.

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Tozaro appoints Jason Slingsby as CEO to lead commercial strategy in cell and gene therapy sector

Pharmafile

Tozaro, a technology provider specialising in cell and gene therapy (CGT) manufacturing, has appointed Jason Slingsby (pictured left) as its new chief executive officer (CEO). This supports Tozaros intent to accelerate the commercialisation of its Smart Polymer technology, which aims to enhance downstream viral vector manufacturing in CGT. Slingsby succeeds interim CEO Guy Leaver, who […] The post Tozaro appoints Jason Slingsby as CEO to lead commercial strategy in cell and gene therapy se

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New $1.7b Novartis acquisition to advance novel microRNA inhibitor

European Pharmaceutical Review

Novartis AG has agreed to acquire the biopharmaceutical company Regulus Therapeutics Inc. This deal has potential total equity value of up to approximately $1.7 billion. It involves supporting advancement of Regulus’ lead product candidate, farabursen (RGLS 8429), a microRNA-17 (miR-17) inhibitor being developed to treat autosomal dominant polycystic kidney disease (ADPKD).

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Fierce Healthcare - Untitled Article

Fierce Healthcare

The filing also names brokers eHealth, GoHealth and SelectQuote as defendants, and claims the insurers paid kickbacks to boost Medicare Advantage enrollment.

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US is planning $500m project on 'universal vaccines;' WSJ

pharmaphorum

The US will spend $500m to develop universal vaccines to protect against multiple virus variants, while changes to testing rules are raising concerns

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Remembering W.W. Wickel: The Start of a 150-Year Legacy

Oswald's

When I returned to Oswalds Pharmacy in 2016, one of the first things I did was sit down with my grandparents, Bob and Jean Andersonthe fourth-generation owners of the business. Theyve lived in the same Naperville home that my great-great-great-grandfather, William Wallace Wickel, built back in 1892. Its a house filled with stories even if some are a little fuzzy.

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Fierce Healthcare - Untitled Article

Fierce Healthcare

Federal contractor Peraton is attempting to help CMS and DOGE crack down on waste, fraud and abuse with a new commercial offering that is supposed to deliver a 100x return on investment.

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J&J scores FDA OK for immune drug touted as future blockbuster

PharmaVoice

The company has predicted that Imaavy — now approved for myasthenia gravis — could eventually earn more than $5 billion in annual sales at its peak.

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How long do you take Wegovy for weight loss?

The Checkup by Singlecare

Wegovy (active ingredient semaglutide) is a weight-loss medication that belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. Manufactured by Novo Nordisk, Wegovy is approved by the U.S. Food & Drug Administration (FDA) for weight management in individuals with a body mass index (BMI) of 30 or greater and individuals with or a BMI of 27 who have at least one weight-related health condition, such as high blood pressure , high cholesterol , or Type 2 diabetes.

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Clinigen announces executive appointments to drive growth and investor value

Pharmafile

Clinigen, the global pharmaceutical services group, has announced key leadership changes to accelerate its growth and strengthen its position in the expanding biopharma services market. Nihad Hasagic (pictured left) has been appointed senior vice president (SVP) of Clinigen Lifecycle Services (CLS), reporting directly to CEO Jerome Charton. CLS supports pharmaceutical and biotech clients across the […] The post Clinigen announces executive appointments to drive growth and investor value ap

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Fierce Healthcare - Untitled Article

Fierce Healthcare

Aetna will exit the individual markets in 2026, less than five years after making a return to this space.

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CDC’s annual HIV report is missing crucial data

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning. It’s Liz here again, subbing for Theresa on this first day of May. Happy International Workers Day , Beltane , or Mayday to all who celebrate.

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Fierce Healthcare - Untitled Article

Fierce Healthcare

The analysis of published research on various treatments for gender dysphoria was denounced as politically motivated, selectively narrow and dangerous to LGBTQ+ patients and care delivery.

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