Thu.Dec 01, 2022

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Five Things Pharmacists Should Know About Ventilator Associated Pneumonia (VAP)

IDStewardship

In this article a pharmacist with advanced training and experience in infectious diseases discusses five things pharmacists should know about ventilator associated pneumonia (VAP). Authored By: Lucia Rose, PharmD, BCIDP. Article Posted 1 December 2022. It was the fall of 2009; I was a proud PGY-1 resident at UMass Medical Center rounding with a large team in the ICU.

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Stories from the lab: Researchers discuss innovative treatments for cancers of the blood

PhRMA

The biopharmaceutical industry is one of the most research-intensive of all sectors in the U.S. economy and supports a broad range of STEM jobs through R&D and manufacturing. At the backbone of the biopharmaceutical ecosystem are its researchers. Each day, in labs across the country, these individuals work tirelessly on the front lines of research and development to help bring novel medicines to patients.

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Safety Questions Remain for Alzheimer's Treatment Lecanemab

Drug Topics

Lecanemab is an investigational anti-amyloid beta antibody to treat mild cognitive impairment due to Alzheimer’s disease. It is currently under review by the FDA and a decision is expected by January 6, 2023.

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Machine Learning Helps Predict Which Patients Respond to Immunotherapy

Pharmacy Times

DeepTCR system showed efficacy as a predictive clinical tool and provided information on the biological mechanisms that underlie how patients respond to immunotherapy.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Co-Administering Influenza and Shingles Vaccines May Reduce Vaccine Uptake for the Next Flu Season

Drug Topics

Although it’s safe and recommended to co-administer these shots, research finds a reduction in flu vaccine uptake the following year.

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FDA Approves First-in-Class Microbiota-Based Live Biotherapeutic for C. Difficile Infection

Pharmacy Times

Live-jslm (Rebyota; Ferring Pharmaceuticals) is indicated for the prevention of recurring Clostridioides difficile infection among patients 18 years of age and older after an antibiotic treatment.

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More Trending

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FDA Grants Orphan Drug Designation to ZielBio’s ZB131 for Cholangiocarcinoma

Pharmacy Times

The investigational drug is a monoclonal antibody with a high affinity and specificity for cancer-specific plectin, a cell surface protein that correlates with aggressive tumors and poor prognosis.

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Steps to building a more patient-centric industry

pharmaphorum

Lack of access, strict regulations, and demanding schedules have made it extremely difficult for patients to participate in clinical trials. A 2018 NIH survey found that patients felt clinical trial participation to be inconvenient and burdensome, and nearly half (49.0%) said it disrupted their daily routine. In 2021, a CISCRIP Perceptions and Insights Study reported more disruption to daily routines compared to previous years, citing length of visits, travel, and diagnostic tests as top burdens

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Domvanalimab Combination Shows Clinically Meaningful Progression-Free Survival in Lung Cancer

Pharmacy Times

Data from the fourth interim analysis of the ARC-7 trial shows that a combination of Fc-silent anti-TIGIT and anti-PD-1 molecules are effective for objective response rates in certain lung cancers.

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STAT+: With early data and a possible advantage, Amgen enters the obesity drug race 

STAT

Amgen released detailed data on Thursday suggesting an early-stage drug can induce significant weight loss in patients with obesity, with less frequent dosing than current treatments but a safety profile that remains unclear. The results for the molecule, codenamed AMG133, throw Amgen in a long-gestating race with other major drugmakers that burst into the popular press this year.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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COVID-19 Found to Elevate Risk of Seizures More Than Influenza

Pharmacy Times

Individuals who had COVID-19 were 55% more likely to develop epilepsy or seizures over the following 6 months than those who had influenza.

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As major hospitals now bill for some patient-provider messaging, the move could usher wider adoption

Fierce Healthcare

As major hospitals now bill for some patient-provider messaging, the move could usher wider adoption. dmuoio. Thu, 12/01/2022 - 17:48.

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Understanding the Origins and How to Heal From Codependency

Pharmacy Times

Commonly known as “relationship addiction,” co-dependency involves emotional, spiritual, physical, or mental enmeshment with a loved one.

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‘A constant information lag’: The troubled recall of Philips CPAP machines underscores flaws in device oversight

STAT

The ongoing recall of millions of breathing devices made by Philips has been botched and belabored at nearly every turn: It took more than a decade after users first reported the soundproofing foam in their CPAP and BPAP machines breaking down for Philips to issue a recall. Even after the recall notice was issued, it failed to reach many patients, and many are still waiting on their promised replacement devices or refunds, some of which had to be recalled themselves.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharmacists Participating in Advanced Pain Management Modalities for Refractory Pain

Pharmacy Times

Patient selection is a key factor in the safe and effective administration of advanced pain management modalities.

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Opinion: The U.S. doesn’t need a new ‘essential hospital’ designation

STAT

A recent essay in Health Affairs, a prominent health care journal, proposed a useful-sounding idea: The government should create a new federal designation for “essential hospitals” — hospitals that, according to their own metrics, serve a safety-net role but aren’t currently recognized as such. But it isn’t useful at all.

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24th Annual NACDS Foundation Dinner raises more than $1.5M

Drug Store News

The event raised more than $1.5 million, which will help support evidence-based research, pharmacy education and philanthropic initiatives to improve patient outcomes and advance population health.

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STAT+: Afraid of pharma pushback, a health data broker puts up a barrier to drug pricing information

STAT

At a time when many Americans are clamoring for more transparency into prescription drug pricing, one key provider of that data is making it harder to access the information. A new venture called Merative — which was formed recently from the ashes of IBM’s Watson Health division — has decided it will no longer provide the media with pricing changes for specific medicines.

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The “Graziella Molinari Women in Pharma Award” Announced for 2022 Edition at the ISPE Italy Affiliate

ISPE

The “Graziella Molinari Women in Pharma Award” Announced for 2022 Edition at the ISPE Italy Affiliate. Trudy Patterson. Thu, 12/01/2022 - 14:46. iSpeak Blog. iSpeak. The “Graziella Molinari Women in Pharma Award” Announced for 2022 Edition at the ISPE Italy Affiliate. 1 December 2022. Excellence is everywhere, and it must be illuminated. For the fourth consecutive year, the annual ISPE Italy Affiliate Award for women in the pharmaceutical sector will be organized by the local group of ISPE Women

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Rough investments, rising costs push Cleveland Clinic's 9-month losses past $1.5B

Fierce Healthcare

Rough investments, rising costs push Cleveland Clinic's 9-month losses past $1.5B. dmuoio. Thu, 12/01/2022 - 15:00.

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Can VR technology make physical therapy fun? – the pharmaphorum podcast

pharmaphorum

In the newest episode of the pharmaphorum podcast, editor in chief Jonah Comstock chats with Gita Barry, EVP and GM of Immersive Healthcare at Penumbra, a therapeutic VR company. Penumbra uses VR to improve the physical therapy experience – both making it more fun for patients and delivering certain types of therapy, like mirror therapy, more effectively than traditional PT methods.

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Florida panel hands TeamHealth a win in its ongoing battle with UnitedHealthcare

Fierce Healthcare

Florida panel hands TeamHealth a win in its ongoing battle with UnitedHealthcare. pminemyer. Thu, 12/01/2022 - 15:34.

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Study: More Than Half of US Adults Not Aware of Link Between Alcohol, Cancer

Pharmacy Times

Data suggest that few US adults are aware that wine can increase the risk of cancer.

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UnitedHealth, American Nurses Foundation team on pilot to tackle nurse burnout

Fierce Healthcare

UnitedHealth, American Nurses Foundation team on pilot to tackle nurse burnout. pminemyer. Thu, 12/01/2022 - 16:56.

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Non-toxic and addiction free: The promise of a new pain med

PharmaVoice

Why South Rampart Pharma’s novel new molecule could be a key to solving the global pain epidemic.

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BJ’s Wholesale Club launches retail media program

Drug Store News

BJ’s Media Edge, which utilizes Microsoft PromoteIQ, looks to offer brands a comprehensive advertising solution to connect with shoppers.

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Senators to Medicare Advantage plans: Get your provider directories in order

Fierce Healthcare

Senators to Medicare Advantage plans: Get your provider directories in order. rking. Thu, 12/01/2022 - 16:41.

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STAT+: Pharmalittle: Roche Alzheimer’s drug didn’t clear enough amyloid; startup to seek approval of nasal swab version of naloxone

STAT

Good morning, Jason Mast here filling in for Ed. There are many types of coffee in this world and I must admit to you that I, preternaturally lazy and languorous, have become partial to instant. Don’t tell Ed, as I’m sure he will find it heresy. But I would point out that much of the world is on my side. Anyway, here’s some news.

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mRNA non-vaccine therapeutics to generate $2 billion by 2028

European Pharmaceutical Review

According to GlobalData’s recent report , a total of five marketed messenger RNA (mRNA) non-vaccine products by 2028 will generate over $2 billion, generated by the approval of pipeline agents. The analytics company asserted that despite no mRNA non-vaccine therapeutics currently being in the market, this statistic is derived from the combined revenue expected from Moderna, Ultragenyx, Omega Therapeutics, and BioNTech’s investigational therapies for cancer and rare genetic diseases, all in

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FaceTory’s Urban Calm collection supports skin through fermentation

Drug Store News

The Urban Calm collection features products that contain a blend of fermented-focused ingredients, as well as antioxidant-rich vitamins and minerals.

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Eli Lilly dumps Innovent's PD-1 after FDA rebuff, nixing high-profile Chinese cancer drug

Fierce Pharma

Eli Lilly dumps Innovent's PD-1 after FDA rebuff, nixing high-profile Chinese cancer drug. aliu. Thu, 12/01/2022 - 15:03.

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Fecal Microbiota Product Rebyota Receives FDA Approval

Drug Topics

The treatment is approved for preventing recurrent Clostridioides difficile infections.

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Texas docs file latest legal challenge to surprise billing rule, arguing arbitration process unfair

Fierce Healthcare

Texas docs file latest legal challenge to surprise billing rule, arguing arbitration process unfair. rking. Thu, 12/01/2022 - 14:43.

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5 final FDA action dates to watch this year

PharmaVoice

A potential flurry of regulatory activity could be on the horizon yet this year — and several key drug approvals are at stake.

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