Thu.Dec 01, 2022

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Co-Administering Influenza and Shingles Vaccines May Reduce Vaccine Uptake for the Next Flu Season

Drug Topics

Although it’s safe and recommended to co-administer these shots, research finds a reduction in flu vaccine uptake the following year.

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Five Things Pharmacists Should Know About Ventilator Associated Pneumonia (VAP)

IDStewardship

In this article a pharmacist with advanced training and experience in infectious diseases discusses five things pharmacists should know about ventilator associated pneumonia (VAP). Authored By: Lucia Rose, PharmD, BCIDP. Article Posted 1 December 2022. It was the fall of 2009; I was a proud PGY-1 resident at UMass Medical Center rounding with a large team in the ICU.

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Safety Questions Remain for Alzheimer's Treatment Lecanemab

Drug Topics

Lecanemab is an investigational anti-amyloid beta antibody to treat mild cognitive impairment due to Alzheimer’s disease. It is currently under review by the FDA and a decision is expected by January 6, 2023.

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Stories from the lab: Researchers discuss innovative treatments for cancers of the blood

PhRMA

The biopharmaceutical industry is one of the most research-intensive of all sectors in the U.S. economy and supports a broad range of STEM jobs through R&D and manufacturing. At the backbone of the biopharmaceutical ecosystem are its researchers. Each day, in labs across the country, these individuals work tirelessly on the front lines of research and development to help bring novel medicines to patients.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Non-toxic and addiction free: The promise of a new pain med

PharmaVoice

Why South Rampart Pharma’s novel new molecule could be a key to solving the global pain epidemic.

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Fecal Microbiota Product Rebyota Receives FDA Approval

Drug Topics

The treatment is approved for preventing recurrent Clostridioides difficile infections.

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December 2022: In This Issue

Drug Topics

A look at what’s to come in the December issue of Drug Topics®.

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Machine Learning Helps Predict Which Patients Respond to Immunotherapy

Pharmacy Times

DeepTCR system showed efficacy as a predictive clinical tool and provided information on the biological mechanisms that underlie how patients respond to immunotherapy.

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Rough investments, rising costs push Cleveland Clinic's 9-month losses past $1.5B

Fierce Healthcare

Rough investments, rising costs push Cleveland Clinic's 9-month losses past $1.5B. dmuoio. Thu, 12/01/2022 - 15:00.

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FDA Approves First-in-Class Microbiota-Based Live Biotherapeutic for C. Difficile Infection

Pharmacy Times

Live-jslm (Rebyota; Ferring Pharmaceuticals) is indicated for the prevention of recurring Clostridioides difficile infection among patients 18 years of age and older after an antibiotic treatment.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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UnitedHealth, American Nurses Foundation team on pilot to tackle nurse burnout

Fierce Healthcare

UnitedHealth, American Nurses Foundation team on pilot to tackle nurse burnout. pminemyer. Thu, 12/01/2022 - 16:56.

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COVID-19 Found to Elevate Risk of Seizures More Than Influenza

Pharmacy Times

Individuals who had COVID-19 were 55% more likely to develop epilepsy or seizures over the following 6 months than those who had influenza.

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As major hospitals now bill for some patient-provider messaging, the move could usher wider adoption

Fierce Healthcare

As major hospitals now bill for some patient-provider messaging, the move could usher wider adoption. dmuoio. Thu, 12/01/2022 - 17:48.

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Study: More Than Half of US Adults Not Aware of Link Between Alcohol, Cancer

Pharmacy Times

Data suggest that few US adults are aware that wine can increase the risk of cancer.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Florida panel hands TeamHealth a win in its ongoing battle with UnitedHealthcare

Fierce Healthcare

Florida panel hands TeamHealth a win in its ongoing battle with UnitedHealthcare. pminemyer. Thu, 12/01/2022 - 15:34.

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Understanding the Origins and How to Heal From Codependency

Pharmacy Times

Commonly known as “relationship addiction,” co-dependency involves emotional, spiritual, physical, or mental enmeshment with a loved one.

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Senators to Medicare Advantage plans: Get your provider directories in order

Fierce Healthcare

Senators to Medicare Advantage plans: Get your provider directories in order. rking. Thu, 12/01/2022 - 16:41.

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FDA Grants Orphan Drug Designation to ZielBio’s ZB131 for Cholangiocarcinoma

Pharmacy Times

The investigational drug is a monoclonal antibody with a high affinity and specificity for cancer-specific plectin, a cell surface protein that correlates with aggressive tumors and poor prognosis.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Is Digital Health Closing Gaps in Health Equity?

Fierce Healthcare

Is Digital Health Closing Gaps in Health Equity? ncapone. Thu, 12/01/2022 - 12:54.

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Pharmacists Participating in Advanced Pain Management Modalities for Refractory Pain

Pharmacy Times

Patient selection is a key factor in the safe and effective administration of advanced pain management modalities.

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How retail pharmacies can use technology to conquer compliance

Drug Store News

IoT sensing tools offer a simplified solution to regulatory compliance complexities.

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Domvanalimab Combination Shows Clinically Meaningful Progression-Free Survival in Lung Cancer

Pharmacy Times

Data from the fourth interim analysis of the ARC-7 trial shows that a combination of Fc-silent anti-TIGIT and anti-PD-1 molecules are effective for objective response rates in certain lung cancers.

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STAT+: Gilead wins a key battle with the CDC over patents for its Truvada HIV pill

STAT

Gilead Sciences won a key round in its battle with the U.S. government over allegations that the Centers for Disease Control and Prevention breached several contracts and “secretly” obtained patents stemming from research that led to the groundbreaking Truvada pill for preventing HIV. As part of a broader fight with the agency over research and resulting patent rights to the medication, the company had filed a lawsuit in 2020 alleging the CDC violated the terms of a 15-year-old col

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BJ’s Wholesale Club launches retail media program

Drug Store News

BJ’s Media Edge, which utilizes Microsoft PromoteIQ, looks to offer brands a comprehensive advertising solution to connect with shoppers.

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US FDA approves Ferring’s Rebyota for Clostridioides difficile infection

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted approval for Ferring Pharmaceuticals’ faecal microbiota product, Rebyota, to prevent Clostridioides difficile infection (CDI) recurrence in people aged 18 years and above. A live biotherapeutic, Rebyota is intended for usage following the completion of antibiotic treatment. Rebyota’s safety and efficacy were analysed in the largest trial programme in the microbiome-based therapeutics field, including five trials enrolling over 1,000 subjects.

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STAT+: With early data and a possible advantage, Amgen enters the obesity drug race 

STAT

Amgen released detailed data on Thursday suggesting an early-stage drug can induce significant weight loss in patients with obesity, with less frequent dosing than current treatments but a safety profile that remains unclear. The results for the molecule, codenamed AMG133, throw Amgen in a long-gestating race with other major drugmakers that burst into the popular press this year.

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Texas docs file latest legal challenge to surprise billing rule, arguing arbitration process unfair

Fierce Healthcare

Texas docs file latest legal challenge to surprise billing rule, arguing arbitration process unfair. rking. Thu, 12/01/2022 - 14:43.

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Opinion: The U.S. doesn’t need a new ‘essential hospital’ designation

STAT

A recent essay in Health Affairs, a prominent health care journal, proposed a useful-sounding idea: The government should create a new federal designation for “essential hospitals” — hospitals that, according to their own metrics, serve a safety-net role but aren’t currently recognized as such. But it isn’t useful at all.

Hospitals 101
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Could acoziborole eliminate sleeping sickness in Africa?

European Pharmaceutical Review

Results from a Phase II/III study , published in The Lancet , showed a single, oral dose of acoziborole was up to 95 percent successful in treating sleeping sickness (human African trypanosomiasis). About the Phase II/III study. Between 2016 and 2019, DNDi and its partners led an open-label, Phase II/III study to assess the safety and efficacy of acoziborole in patients with early- and late-stage g-HAT. 208 patients were recruited at 10 hospitals in the Democratic Republic of the Congo (DRC) and

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STAT+: Afraid of pharma pushback, a health data broker puts up a barrier to drug pricing information

STAT

At a time when many Americans are clamoring for more transparency into prescription drug pricing, one key provider of that data is making it harder to access the information. A new venture called Merative — which was formed recently from the ashes of IBM’s Watson Health division — has decided it will no longer provide the media with pricing changes for specific medicines.

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mRNA non-vaccine therapeutics to generate $2 billion by 2028

European Pharmaceutical Review

According to GlobalData’s recent report , a total of five marketed messenger RNA (mRNA) non-vaccine products by 2028 will generate over $2 billion, generated by the approval of pipeline agents. The analytics company asserted that despite no mRNA non-vaccine therapeutics currently being in the market, this statistic is derived from the combined revenue expected from Moderna, Ultragenyx, Omega Therapeutics, and BioNTech’s investigational therapies for cancer and rare genetic diseases, all in

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Kellogg’s satisfies cravings with Krave, Froot Loops Jumbo Snax

Drug Store News

New product launches include Krave Double Chocolate Brownie Batter Cereal and Froot Loops with Marshmallows Jumbo Snax.

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How to become a regulatory affairs pharmacist

The Checkup by Singlecare

The pharmaceutical industry is highly regulated, and for a good reason. Laws and regulations are set to ensure that consumers and patients can access safe and effective medications, medical devices, and other products. In order to test, market, and release drugs onto the market, pharmaceutical companies must abide by government regulations and oversight processes. .