Tue.May 23, 2023

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Nalmefene Nasal Spray for Emergency Opioid Overdose Treatment Gets FDA Approval

Drug Topics

The newly FDA-approved prescription product delivers nalmefene to the nasal cavity to reverse the effects of opioid overdose.

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The power of genetics — how research into gene sequencing could revolutionize biopharma

PharmaVoice

Ancient DNA from a deer tooth. A new way to connect genes with disease. Biological super-computing. These genetic advances could play a part in our biopharma future.

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Why Purchasing In The Pharmacy Industry Is So Unique

Drug Topics

Drug Topics is joined by Wayne Boese, the VP of Sales at American Associated Pharmacies, for a conversation about purchasing in the pharmacy world, "shopping" for the best prices, and more.

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Biotechs blast experiments into space

PharmaVoice

Conducting life sciences research in space’s microgravity could have far-ranging implications for drug development on Earth.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Examining the Patient Journey in TRD

Drug Topics

The panel of experts highlight the patient journey commonly experienced in search of a treatment-resistant depression diagnosis.

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Probiotic Use Has Increased in Neonatal ICUs, But Further Data Are Still Needed

Pharmacy Times

In neonatal intensive care units, probiotic usage was associated with a decline in necrotizing enterocolitis, but not with sepsis or mortality rates.

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More Trending

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European biotechs choosing Switzerland as base, research shows

European Pharmaceutical Review

New research by IQVIA and recently published in the 2023 Swiss Biotech Report shows that 20 percent of European biotech companies are now headquartered in Switzerland. Sixty three out of a total of 265 companies settling in Switzerland were biotechs. This makes it the second most important sector after ICT, the research found. 2022 statistics by the Swiss federal government confirm that the trend to base here is continuing.

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SLFN12 Expression is Found in Cells Positive for HIV Transcripts But Negative for HIV Protein

Pharmacy Times

A barrier in effectively treating HIV has been the latency of infected CD4+ T cells, which are often treatment-resistant and contribute to the persistence nature of the virus.

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CMS proposed rule aims to shed light on prescription drug costs for Medicaid

Fierce Healthcare

CMS proposed rule aims to shed light on prescription drug costs for Medicaid hlandi Tue, 05/23/2023 - 23:18

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Independent Rx Forum - Congressional Trends on PBM Reform

Pharmacy Times

Anne Cassity, JD, senior vice president of Public Affairs at the National Community Pharmacists Association discusses congressional and lawmaker trends on pharmacy benefits manager reform with guests, Adam Harbison and Kaite Krell.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Walgreens asks federal court to toss 'staggering' $642M arbitration award to Humana

Fierce Healthcare

Walgreens asks federal court to toss 'staggering' $642M arbitration award to Humana hlandi Tue, 05/23/2023 - 16:17

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Research Suggests Risk of Long COVID is Higher for Individuals in Underserved Areas

Pharmacy Times

The risk of long COVID-19 in females in the least deprived areas was comparable to the risk of males in the most deprived areas.

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Cleveland Clinic notches 0.9% operating margin, $336M gain in Q1 2023

Fierce Healthcare

Cleveland Clinic notches 0.

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What does generative AI mean for health care? We asked the experts

STAT

Health care companies are racing to incorporate generative AI tools into their product pipelines and IT systems after the technology displayed an ability to perform many tasks faster, cheaper — and sometimes better — than humans. But the rush to harness the power of so-called large language models, which are trained on vast troves of data, is outpacing efforts to assess their value.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Minnesota lawmakers cut nurse staffing ratios from union-backed bill due to Mayo Clinic, industry pushback

Fierce Healthcare

Minnesota lawmakers cut nurse staffing ratios from union-backed bill due to Mayo Clinic, industry pushback dmuoio Tue, 05/23/2023 - 15:14

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HIV rates decline in U.S., data show, but disparities persist

STAT

The latest accounting of HIV incidence in the United States is a mixed bag. Overall estimated new infections dropped 12% in 2021 compared to 2017, according to data released Tuesday by the Centers for Disease Control and Prevention. But the American South — which has had a longtime HIV problem compared with other areas across the U.S. — was the only region to show a “statistically significant decline.

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The continued questions over new Alzheimer’s treatments

pharmaphorum

The continued questions over new Alzheimer’s treatments Mike.

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STAT+: Biotech launches with $300 million, joint venture to expedite RNA drug development

STAT

Biotech venture capital may be pacing at a six-year low, but one startup just managed to raise a $300 million Series A mega-round. The round was raised by ReNAgade Therapeutics, a new biotech developing what it hopes will be a one-stop shop for medicines targeting RNA, the genetic blueprints that cells use to make proteins instrumental in numerous diseases.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Avrobio to sell cystinosis gene therapy to Novartis for $87.5m

Pharmaceutical Technology

Avrobio has announced a deal to sell its investigational haematopoietic stem cell (HSC) gene therapy programme , designed to treat cystinosis, to Novartis in an all-cash deal valued at $87.5m. Novartis will receive an exclusive licence for intellectual property related to the gene therapy platform of Avrobio for use in cystinosis and for other assets.

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Social media risks for youth mental health highlighted in new surgeon general report

STAT

Amid what he called the worst youth mental health crisis in recent memory, U.S. Surgeon General Vivek Murthy issued an advisory Tuesday warning about social media’s impact on developing young brains. “Through the last two and a half years I’ve been in office, I’ve been hearing concerns from kids and parents,” Murthy told STAT.

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Ferrero to launch Kinder Chocolate at the 2023 Sweets & Snacks Expo

Drug Store News

The new chocolate bar contains a milky filling and hits shelves this August, the company said.

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Opinion: Three ways to test medical AI for safety

STAT

This article is adapted from “ The AI Revolution in Medicine: GPT-4 and Beyond ,” by Peter Lee, Carey Goldberg, and Isaac Kohane, published by Pearson. “Thrashing.” That’s what old-school computer scientists called it when an operating system is running so many tasks at once that just switching among them basically crashes it.

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US FDA approves Blueprint Medicines’ indolent systemic mastocytosis therapy

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted approval for Blueprint Medicines’ Ayvakit (avapritinib) as the first and only treatment for indolent systemic mastocytosis (ISM) in adult patients. The precision therapy has been designed for potently and selectively inhibiting KIT D816V, which is the main underlying driver of the disease. It received FDA approval to treat ISM, advanced SM, including SM with an associated haematological neoplasm (SM-AHN) and mast cell leukemia (MCL), and aggr

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STAT+: Learning to treat long COVID could help those struggling with chronic fatigue syndrome, too

STAT

CONCORD, N.H. — Veronica Dane had always been active, from playing soccer as a kid to working a demanding job as a critical care nurse. Until, one day, she just couldn’t do it anymore. She started eliminating activities and duties, whittling away the things that had once brought joy and a steady income but were now, instead, bringing unbearable physical pain.

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Industry Voices—Want young people to trust healthcare? Invest in primary care now

Fierce Healthcare

Industry Voices—Want young people to trust healthcare?

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STAT+: Achieve Life Sciences drug helps smokers quit in trial but would face stiff competition if approved

STAT

Seattle biotech Achieve Life Sciences on Tuesday announced an experimental drug meant to help people quit smoking did exactly that in a clinical trial, paving the way for the company to seek approval for a product that would face stiff competition. In the study, dubbed ORCA-3, participants took either the smoking cessation drug cytisinicline or a placebo pill three times a day for six or 12 weeks.

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Machine learning can predict outcomes for inkjet printed pharmaceuticals

European Pharmaceutical Review

Using inkjet printing, optimised machine learning (ML) models predicted the printability of drug formulations with an accuracy of 97.22 percent, a paper published in International Journal of Pharmaceutics: X has shown. Inkjet printing makes formulation and printing parameter optimisation time-consuming. This is especially true for additive manufacturing and the production of unique dosage forms and personalised medicines.

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ChatGPT in medicine: STAT answers readers’ burning questions about AI

STAT

Artificial intelligence is often described as a black box: an unknowable, mysterious force that operates inside the critical world of health care. If it’s hard for experts to wrap their heads around at times, it’s almost impossible for patients or the general public to grasp. While AI-powered tools like ChatGPT are swiftly gaining steam in medicine, patients rarely have any say — or even any insight — into how these powerful technologies are being used in th

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Survey: 58% of Americans likely to first seek non-emergency health care at pharmacies

Drug Store News

Some 81% say they trust a pharmacist, nurse or nurse practitioner to diagnose minor illnesses and prescribe medications to treat them.

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STAT+: Congress highlighted a chemo drug’s price to blast PBMs — but it’s not a PBM issue

STAT

WASHINGTON — Congress blasted drug middlemen at a hearing Tuesday, with multiple lawmakers pointing to a huge discrepancy between how much a chemo drug costs at CVS and its price from Mark Cuban’s Cost Plus Drugs. There’s just one problem: PBMs don’t have anything to do with that discrepancy. The chemo drug in question, Imatinib, costs $17,000 at CVS and just $72 at Cost Plus Drugs.

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'Podnosis': The food is medicine movement and the top-paid healthcare and payer execs

Fierce Healthcare

'Podnosis': The food is medicine movement and the top-paid healthcare and payer execs tcarey Tue, 05/23/2023 - 13:26

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FDA budget battles, prisons’ sobering Covid response & BIO’s CEO search is on

STAT

You’re reading the web edition of D.C. Diagnosis. Sign up here to receive this newsletter in your inbox on Tuesdays and Thursdays. House committee sets up for budget fight UPDATE: Late on Monday night, House Appropriations Chair Kay Granger indefinitely postponed markup of this FDA budget bill, citing the ongoing debt ceiling talks.

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Is it safe to mix Wellbutrin and caffeine?

The Checkup by Singlecare

Wellbutrin ( bupropion ) is a prescription antidepressant medication. Though most commonly prescribed to treat depression, it is sometimes prescribed off-label for attention-deficit/hyperactivity disorder (ADHD) or (the 12-hour extended-release form) smoking cessation. If you or someone you know is taking Wellbutrin, the underlying condition—depression or ADHD —might already cause sleep problems.