Wed.Nov 06, 2024

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Switching from Ozempic to Mounjaro

The Checkup by Singlecare

Ozempic (semaglutide) and Mounjaro (tirzepatide) are two brand-name medications approved by the Food and Drug Administration (FDA) to help treat Type 2 diabetes. Because they suppress appetite, these drugs are sometimes prescribed off-label for weight loss. Specifically, the brand names Ozempic and Mounjaro are not FDA approved for this use, but medications with the same active ingredients have been FDA approved as weight loss injections under the brand names Wegovy and Zepbound.

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STAT+: Novo’s earnings report sends shares up, as obesity drug sales show continued growth

STAT

LONDON — Sales of Novo Nordisk’s obesity drug Wegovy jumped in the third quarter, the company said Wednesday as it reported quarterly profits that were in line with analyst expectations. Novo’s third quarter performance will be seen as a win for the company, particularly after Eli Lilly — its rival in the booming obesity drug market — reported earnings last week that fell below forecasts.

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Unlock the Benefits of Centralized Fulfillment for Pharmacists: A Comprehensive Guide

Drug Topics

Streamline your pharmacy operations with centralized fulfillment. Discover how automation and advanced software can improve patient care, reduce operational errors, and create a better work environment for pharmacists. Download our whitepaper to learn how centralized fulfillment can address rising prescription volumes and staffing shortages. Request a consultation today to explore the best solution for your pharmacy.

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Opinion: Pharma’s ethically questionable sites essentially sell drugs directly to consumers

STAT

Want to self-prescribe a prescription drug? No problem! Some of the largest pharmaceutical companies in the U.S. are piloting websites that essentially sell their drugs directly to consumers. This unprecedented move launches a new dystopic era: pharmaceutical companies as health care provider, no pesky physician middlemen needed. It’s what the pharmaceutical industry has always wanted: They have long viewed physicians as inconvenient barriers between the company and their customers.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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First-of-a-kind EU approval granted for eosinophilic esophagitis medicine

European Pharmaceutical Review

Dupixent (dupilumab) has been approved by the European Medicines Agency (EMA) as the first treatment for young children with eosinophilic esophagitis in the EU. This authorisation is based on Phase III data which found that 68 percent of children aged one to 11 years given Dupixent (dupilumab) achieved histological disease remission at 16 weeks. This result was maintained for up to one year.

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SolasCure partners with US Army for better wound care technology

Pharmafile

SolasCure, a biotechnology company which is dedicated to working towards filling the current market gap in debridement – the removal of neurotic tissue to encourage healing – and healing solutions for chronic wounds has announced a partnership with the US Army’s Institute of Surgical Research (USAISR). The partnership has aims to improve the current solutions […] The post SolasCure partners with US Army for better wound care technology appeared first on Pharmafile.

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Teva's generics and biosimilars fuel another booming quarter

Fierce Pharma

As other biopharma giants have divested their generics units to focus on the development and commercialization of innovative drugs, Teva has relied on its copycat business to help trigger its rebou | Teva revealed booming third-quarter sales for its generics and biosimilars. In the U.S., revenue from the knockoffs came in at $1.1 billion, which was a 30% increase year over year.

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Who You Gonna Email? Digital Health Question Busters!

The FDA Law Blog

By Jennifer D. Newberger — Though digital health is not new, it can still often be difficult to determine with precision the regulatory requirements applicable to a particular software product. Sometimes this is because FDA has not opined on a specific set of facts, but more often it is because FDA seems to take different approaches to the same technology offered by different companies.

FDA
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STAT+: Biotech and pharma executives on what Trump and RFK Jr. could mean for the industry

STAT

With Donald Trump now poised to become U.S. president for the second time in January, biotech and pharmaceutical leaders are preparing for the shift to an administration with a complicated history. Trump has positioned himself as business-friendly, but has criticized “Big Pharma” over high drug costs. During the course of the Covid-19 pandemic, he was supportive of the pharmaceutical industry’s efforts to develop vaccines, but his campaign has more recently embraced vaccine

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Drug Shortages More Likely in US Than in Canada

Drug Topics

Researchers compared the issue of drug shortages and supply chain challenges between the US and Canada.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: AstraZeneca says China has detained a senior executive

STAT

The executive in charge of AstraZeneca operations in China is under detention by Chinese authorities who are investigating employees there, the company said. The disclosure comes after AstraZeneca last week acknowledged that Leon Wang, an executive vice president who also oversees international operations for the drugmaker, was being investigated along with a “small number” of employees.

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Trusting COVID-19 Vaccine Science Crucial in Vaccine Acceptance Among US Adults

Drug Topics

A recent study found that losing a family member or a friend to COVID-19 within the past year led to higher levels of vaccine acceptance.

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A diabetes drug, twice rejected, stumbles again — but its developer persists

PharmaVoice

After multiple rejections, Lexicon Pharmaceuticals is inching toward an FDA decision date next month for its adjunct type 1 diabetes therapy.

FDA
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NCPA 2024 Meeting Recap

Drug Topics

Checkout some of the most important sessions and video interviews from the 2024 National Community Pharmacists Association (NCPA) Annual Convention and Expo.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Novavax coughs up $123.8M to settle COVID vaccine supply dispute with UK

Fierce Pharma

Novavax has inked another settlement for a past COVID-19 vaccine supply deal. | Novavax has inked another settlement for a past COVID-19 vaccine supply deal. The Maryland biotech has agreed to pay $123.8 million to end a COVID vaccine supply pact with the U.K.

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Why Vaccination Uptake is Crucial During the Winter Season

Drug Topics

Ruth Carrico, PhD, DNP, APRN, sat down with Drug Topics to discuss the importance of COVID-19 and influenza vaccination.

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Opioid Stewardship Pharmacist: Innovative Approaches to Pain Management

Pharmacy Times

Jeff Boyer, PharmD, BCPS, discusses his role in opioid stewardship at the Southern Arizona VA Healthcare System, highlighting his work in pain management coordination, interdisciplinary collaboration, patient and provider education, and data-driven strategies to support safe opioid use and address the opioid crisis.

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Insulin Icodec Represents A Promising Option for Managing Diabetes, Improving Quality of Life

Drug Topics

Jennifer Goldman, PharmD, CDCES, BC-ADM, FCCP, discusses how insulin icodec differs from existing daily basal insulins and key things pharmacists need to know about the medication.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Cognitive Remediation, Transcranial Direct Current Stimulation Slow Cognitive Decline in At-Risk Older Adults

Pharmacy Times

For up to 6 years, cognitive remediation and transcranial direct current stimulation slowed cognitive decline associated with major depressive disorder in remission and mild cognitive impairment.

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D.C. Diagnosis: MAHA movement unleashed

STAT

You’re reading the web edition of D.C. Diagnosis, STAT’s twice-weekly newsletter about the politics and policy of health and medicine.  Sign up here  to receive it in your inbox on Tuesdays and Thursdays. Hello, and happy Wednesday. We’re here with a special edition today featuring our election coverage of Republicans’ big night.

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Ensure Your Team Is Prepared for PBM Audits

Pharmacy Times

Trent Thiede, PharmD, president of Pharmacy Audit Assistance Service (PAAS) International, discussed how pharmacy teams can remain prepared for audits from pharmacy benefit managers (PBMs).

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Drugs for unmet needs and those from experienced companies had the best chance for successful launches in 2023: report

Fierce Pharma

Drugs for unmet needs and those from experienced companies had the best chance for successful launches in 2023: report kdunleavy Wed, 11/06/2024 - 09:23

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Women Within Health Care Face Financial Disparities and Are More Likely to Experience Burnout

Pharmacy Times

The authors believe that improvements can be made to overlook the motherhood penalty and its associated pay gaps as well as changes to address workforce burnout.

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XRHealth buys NeuroReality in health XR marriage

pharmaphorum

Two players in medical extended reality (XR) – XRHealth and NeuroReality – have come together in a quest to build the biggest company in the sector.Boston, US-based XRHealth is leading the deal, acquiring NeuroReality of the Netherlands for an undisclosed sum, combining their products and expertise in the use of XR and virtual reality software for healthcare applications.

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'Treat These Patients With Compassion': Expert Discusses Pharmacists' Role in Counseling Benzodiazepine Use

Pharmacy Times

Brian Anderson, PharmD, RPh provides important considerations for pharmacists regarding patient use of benzodiazepines.

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After Lilly's GLP-1 sales fumble, Novo reports mixed results on Ozempic, Wegovy

Fierce Pharma

Following a disappointing earnings showing from Eli Lilly last week, Novo Nordisk’s latest report on the performance of its GLP-1 stalwarts Ozempic and Wegovy is more of a mixed bag. | Among Novo’s semaglutide-based drugs, diabetes blockbuster Ozempic fell short of analysts' expectations during the third quarter while weight-loss med Wegovy came above a consensus estimate.

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Bone Marrow Adipocytes May Offer Early Detection of MGUS Progression to Multiple Myeloma

Pharmacy Times

Increased bone marrow adiposity is associated with progression of monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma.

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US Supreme Court reviews case impacting billions in Medicare DSH payments for hospitals

Fierce Healthcare

The U.S. Supreme Court heard oral arguments Monday in a case centered on Congress’ formula for calculating disproportionate share hospital payments. | The U.S. Supreme Court heard oral arguments Monday in a case centered on Congress’ formula for calculating disproportionate share hospital payments.

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ENVISION Trial Results Show UGN-102 Has Long-Term Durability in Patients With Bladder Cancer

Pharmacy Times

Patients with low-grade intermediate-risk non-muscle-invasive bladder cancer who achieved a complete response rate after 3 months of UGN-102 treatment had an 82.3% duration of response at 12 months.

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Wegovy romps ahead after key rival sees slowdown

pharmaphorum

Novo Nordisk's sales of blockbuster obesity drug Wegovy grew by a massive 79% in the third quarter, in a relief to investors after disappointing results three months ago.

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Recap: 2024 American Association of Colleges of Pharmacy Annual Meeting

Pharmacy Times

The 2024 American Association of Colleges of Pharmacy Annual Meeting took place from July 20 to July 23, 2024, in Boston, Massachusetts.

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Alligator pancreatic cancer drug 'nearly doubles' survival

pharmaphorum

New results with Alligator's CD40 agonist mitazalimab show it nearly doubled survival in pancreatic cancer, ahead of phase 3 trial next year.

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RSV Preventative Monoclonal Antibody Could Reduce Disease Incidence in Preterm, Full-term Infants

Pharmacy Times

Clesrovimab reduced RSV-associated hospitalizations and RSV-associated lower respiratory infection hospitalizations by more than 84% and 90% in preterm and full-term infants, respectively.