Wed.May 17, 2023

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FDA Approves Scoliosis Treatment For Young Patients

Drug Topics

The REFLECT Scoliosis Correction System from Globus Medical is intended to correct progressive scoliosis in pediatric patients while simultaneously maintaining stability and motion as well as allowing for future modulated growth.

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Study: Giving an antibiotic to household contacts of people with leprosy slashes chances of spread

STAT

When someone has leprosy, people who live in the same household face the highest odds of contracting the infection. But in a new trial, providing those contacts with a single dose of an antibiotic typically used to treat tuberculosis drastically reduced that risk, researchers reported Wednesday. The trial, which took place in China, corroborates the idea of giving close contacts an antibiotic as a way to reduce the likelihood that the disease spreads, experts said.

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FDA Gives Fast Track Designations To CAR-T Lymphoma Med and Atrial Fibrillation Treatment

Drug Topics

The atrial fibrillation drug, asundexian, may provide protection from thrombotic events without a corresponding increase in bleeding risk.

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FTC expands probe into pharmacy benefit managers to GPOs

Fierce Healthcare

FTC expands probe into pharmacy benefit managers to GPOs pminemyer Wed, 05/17/2023 - 16:36

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Investigators Publish Metric for Recommending Low-dose Aspirin Prophylaxis

Drug Topics

The atrial fibrillation drug, asundexian, may provide protection from thrombotic events without a corresponding increase in bleeding risk.

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Pegfilgrastim Biosimilar for Treatment of Neutropenia Launches

Pharmacy Times

Pegfilgrastim-pbbk is a leukocyte growth factor developed to reduce the onset of infection in patients with non-myeloid malignancies administered myelosuppressive anticancer medications associated with a clinically significant rate of febrile neutropenia.

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A day in the life of a pharma exec: Lyndra’s Patricia Hurter

PharmaVoice

How the CEO starts each day with a ride on one of her horses, reduces daily meetings and uses her network to get through crises like the SVB Bank collapse.

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503B: What Should Pharmacists Know for 2023?

Pharmacy Times

When considering outsourcing, pharmacies should use multistakeholder team to weigh pros and cons.

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Woman of the Week: Genentech’s Veronica Sandoval

PharmaVoice

How the Genentech diversity exec is using a ‘3 Ms’ approach to reduce health disparities and improve access for under-supported communities.

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There Are Food, Drug Interactions Older Adults Should Be Aware Of As They Age

Pharmacy Times

Good practice for older adults is that calories should go down while nutrient intake goes up as they age.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Insurers set to pay $1.1B in premium rebates this year: KFF

Fierce Healthcare

Insurers set to pay $1.

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Novel Study Evaluates Implementation of Long-Acting Injectable PReP In Sexual, Gender Minorities

Pharmacy Times

Preexposure prophylaxis use for HIV continues to be lower than desired in some populations.

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STAT+: Biotech and pharma execs wrestle with the ‘nightmare’ of developing digital biomarkers

STAT

TARRYTOWN, N.Y. — As post-lunch drowsiness settled on an auditorium full of leaders from the drug development industry, Peter Fernandes, CEO of Bellerophon Therapeutics, seized the presentation clicker and jolted them awake. “I don’t believe in dreams, I believe in nightmares,” he told the audience, drawing a laugh.  “And I love nightmares.

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Antidepressant Shows Promising Efficacy in Certain People for Chronic Pain Management

Pharmacy Times

Common chronic pain conditions included in the analysis were fibromyalgia, neuropathic pain, and musculoskeletal pain.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Senators probing largest Medicare Advantage plans over how algorithms factor in care denials

STAT

Senators warned the country’s largest Medicare Advantage insurers at a hearing on Wednesday that they must abide by Medicare’s coverage rules and cannot rely on algorithms to deny care that patients need. Congress is ramping up its oversight, too. Lawmakers in both parties have asked UnitedHealth Group, Humana, and CVS Health’s Aetna for internal documents that “will show how decisions are made to grant or deny access to care, including how they are using [artificial

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Study: Gene Signature Panel Can Accurately Identify Most Treatment-Resistant Melanoma Cases

Pharmacy Times

The panel corresponds to proteins that are abundant in treatment-resistant melanoma cells and may predict resistance to targeted treatment.

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STAT+: A new startup looks to turn the workhorse of gene therapy against cancer

STAT

In 1980, Life and Time magazines introduced America to a new cancer wonder drug: interferon, a protein ripped from the body’s own immune system that showed exciting early results, before ultimately proving both too impotent and too toxic to be useful beyond a couple of malignancies.  Researchers have spent the decades since searching for ways to bottle and repeat the early success seen in those first studies for interferon and another immune-signaling molecule called interleukin-2, w

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GNC focuses on mental wellness support with supplement launches

Drug Store News

The latest launches include Preventive Nutrition Sleep Support, Stress Relief and Focus & Memory.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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The Digital Health Continuum – Connecting Clinical Trials to Care Delivery

Fierce Healthcare

The Digital Health Continuum – Connecting Clinical Trials to Care Delivery mteefey Wed, 05/17/2023 - 16:26

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Target reports Q1 earnings

Drug Store News

Target reported an increase in guest traffic in Q1, with total sales increasing.

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WellSpan Health partners with Emerus to build three 'neighborhood hospitals' in southern Pennsylvania

Fierce Healthcare

WellSpan Health partners with Emerus to build three 'neighborhood hospitals' in southern Pennsylvania dmuoio Wed, 05/17/2023 - 13:52

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STAT+: House panel takes first steps toward reining in hospitals with ‘site-neutral’ changes

STAT

WASHINGTON — A key House panel on Wednesday advanced several health care bills on Wednesday, including its first step toward a controversial effort to equalize Medicare payments between hospitals and physician offices. The Energy and Commerce health subcommittee passed a provision that would ensure Medicare pays the same amount to doctors who administer drugs whether they’re given in a hospital or a physician’s practice.

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Regulatory tracker: Another China-made PD-1 starts FDA journey as Elevar, Hengrui target big cancer type

Fierce Pharma

Regulatory tracker: Another China-made PD-1 starts FDA journey as Elevar, Hengrui target big cancer type aliu Wed, 05/17/2023 - 09:41

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STAT+: Could an upcoming Supreme Court case make the FDA slower?

STAT

WASHINGTON — The Food and Drug Administration could take longer to write regulations and make decisions if the U.S. Supreme Court rules against a long-standing legal doctrine giving agencies extra discretion, food and drug lawyers said Wednesday. The decades-old so-called Chevron doctrine directs judges to defer to reasonable federal agency interpretations of ambiguous or technically challenging aspects of the law.

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VA renegotiates $10B Oracle Cerner EHR contract with stronger performance metrics, bigger penalties

Fierce Healthcare

VA renegotiates $10B Oracle Cerner EHR contract with stronger performance metrics, bigger penalties hlandi Wed, 05/17/2023 - 13:22

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STAT+: FTC widens probe into pharmacy benefit managers to include group purchasing organizations

STAT

The Federal Trade Commission is widening its probe into pharmacy benefit managers and their impact on drug pricing by looking into a pair of group purchasing organizations that are owned by these industry middlemen, but are not well understood outside the industry. By seeking documents from Zinc Health Services and Ascent Health Services, the agency is attempting to unravel what critics complain is an opaque set of business practices and relationships.

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6 health benefits of pickles

The Checkup by Singlecare

People have been preserving foods by the pickling process for centuries. The New York Food Museum reports that people in Mesopotamia may have been pickling foods as early as 2400 BC. And the method is just as popular today as it ever was. How many jars of pickles do you have in your fridge or pantry at this very minute? And do you have different kinds of pickled foods, too?

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Opinion: How ‘Lessons From the Covid War’ falls short

STAT

The stream of books about the government response to the pandemic that began with Michael Lewis’ “The Premonition” has just yielded its most important product to date. “ Lessons From the Covid War ” is public policy analysis at its near-best: lucid, sober, probing, at once analytical and engaging. But the book ultimately comes up a bit short, in ways that interestingly mirror the national response it chronicles and critiques.

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MIF invests in Nectin to investigate multiple myeloma drug candidate

Pharmaceutical Technology

Multiple Myeloma Research Foundation’s (MMRF) venture philanthropy subsidiary Myeloma Investment Fund (MIF) has made an undisclosed investment in Nectin Therapeutics to assess the potential of NTX1088 to treat multiple myeloma. Along with the MIF’s investment, Nectin has so far secured more than $33m from aMoon, Peregrine Ventures, Israel Biotech Fund, Cancer Focus Fund and Integra.

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Opinion: Starting breast cancer screening at 40 saved my life

STAT

In 2015, the year I turned 40, the American Cancer Society updated its guidelines for breast cancer screenings. Instead of urging women to get mammograms beginning at 40, it would now recommend yearly mammograms beginning at age 45, and then every two years from age 55 on. I was greatly relieved by this news. I was a little more than a year into a wildly busy job at a news media startup.

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'Podnosis': How tech can help diagnose neurodevelopmental disabilities and how insurtechs can be profitable

Fierce Healthcare

'Podnosis': How tech can help diagnose neurodevelopmental disabilities and how insurtechs can be profitable tcarey Wed, 05/17/2023 - 09:26

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Opinion: Do chatbots have more time to be empathetic than physicians?

STAT

As an oncologist, Jennifer Lycette gets to know her patients particularly well. She’s doubtful that artificial intelligence could replace that personal connection, but new research based on, of all things, Reddit Q&As, says otherwise. The study, which Lycette wrote about in her essay, “ Why a chatbot might seem more empathetic than a human physician, ” found that chatbot-generated notes were, in some ways, better than notes from actual humans.

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Chinook and Ionis partner to develop ASO therapy for kidney disease

Pharmaceutical Technology

Chinook Therapeutics and Ionis Pharmaceuticals have entered a partnership to develop an antisense oligonucleotide (ASO) therapy to treat a rare, severe chronic kidney disease. The collaboration aims to discover, develop and commercialise an ASO therapy. It will use the precision medicine approach, as well as the deep expertise of Chinook Therapeutics in nephrology and knowledge of Ionis Pharmaceuticals in RNA-targeted therapeutics.

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