How a speech analysis tool could transform diagnosis and research for Alzheimer’s and beyond
PharmaVoice
AUGUST 1, 2022
WinterLight’s machine learning platform assesses speech to more accurately identify neurodegenerative diseases.
Mon.Aug 01, 2022
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Is There Such Thing as Work-Life Balance in Pharmacy?
Pharmacy Times
AUGUST 1, 2022
Many companies overlook the power that workplace culture can have on employee wellness and instead, focus relentlessly on financial metrics.
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A glimpse inside Bristol Myers Squibb’s integration with Celgene
PharmaVoice
AUGUST 1, 2022
Catherine Owen, senior vice president of major markets, discusses the hurdles — and successes — of bringing the two ‘powerhouses’ together.
FDA Approves Rebinyn for Routine Prophylaxis to Prevent Bleeding in Patients with Hemophilia B
Pharmacy Times
AUGUST 1, 2022
Expanded indication for Rebinyn could allow patients with hemophilia B to participate in physical and social activities.
From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Bristol Myers Squibb aims to improve disability diversity in clinical trials
European Pharmaceutical Review
AUGUST 1, 2022
Dubbed Disability Diversity in Clinical Trials (DDiCT), the initiative aims to provide recommendations on how to improve access, engagement, speed of enrolment and participation of people with disabilities in clinical trials. The goal is to “ensure all patient groups are reflective of the real-world population and aligned with the epidemiology of the disease studies,” a statement said.
The Role of Behavioral Economics in Smoking Cessation
Pharmacy Times
AUGUST 1, 2022
Behavioral economics is a tool that can influence patient behaviors using concepts such as choice architecture, nudges, and loss aversion.
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Heavy Alcoholism, ALDH2 rs671 Polymorphism Associated with Higher Risk of Hepatocellular Carcinoma, Mortality
Pharmacy Times
AUGUST 1, 2022
Heavy alcohol intake and ALDH2 rs671 polymorphism are among many risk factors associated with increased risk of hepatocellular carcinoma and mortality in patients with hepatitis B virus-related cirrhosis.
Sarepta says early filing for DMD gene therapy is back on
pharmaphorum
AUGUST 1, 2022
Sarepta is pressing forward with a bold plan to file with the FDA for accelerated approval of its gene therapy SRP-9001 for Duchenne muscular dystrophy (DMD) in the next few months, with a view to making it available in sometime around the middle of 2023. The US biotech – which already has three antisense drugs for DMD on the market – had said earlier it was planning to delay the application into 2023, so the new announcement marks an acceleration of its plans.
COVID-19 Pandemic Dramatically Increased Childcare Stress Among Health Care Workers
Pharmacy Times
AUGUST 1, 2022
Researchers found high levels of childcare stress among female and racial minority health care workers, supporting new programs and wellbeing initiatives.
Microparticles could form self-boosting vaccines
European Pharmaceutical Review
AUGUST 1, 2022
Researchers have developed microparticles that can be tuned to deliver their payload at different time points. According to the authors, the technology could enable the creation of “self-boosting” vaccines that only need to be administered once, which could be particularly beneficial for childhood vaccinations in regions with limited access to medical care.
Position Your Pharmacy for Expansion
Speaker: Chris Antypas and Josh Halladay
Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.
Treatment of Precancerous Growths Decrease Progression to Anal Cancer in Patients With HIV
Pharmacy Times
AUGUST 1, 2022
Investigators found that treatment of high-grade squamous intraepithelial lesions in patients with HIV reduced anal cancer incidence by approximately 57%.
Big Data Steering Group to enhance data quality and discoverability under new workplan
European Pharmaceutical Review
AUGUST 1, 2022
The joint Big Data Steering Group of the European Medicines Agency (EMA) and the Heads of Medicines Agencies (HMA) has published a third workplan, setting actions to be delivered by 2025. According to EMA, the new plan will further enhance the efficient integration of data analysis into the regulatory evaluation of medicinal products. “Using novel technologies and the evidence generated from big data will benefit public health by accelerating medicine development, improving treatment outcomes an
BMS’ plan to move Opdivo into adjuvant RCC gets knocked back
pharmaphorum
AUGUST 1, 2022
Bristol-Myers Squibb has revealed that its checkpoint inhibitor combination of Opdivo and Yervoy failed a phase 3 trial as adjuvant (post-surgery) therapy for renal cell carcinoma (RCC), the most common form of kidney cancer. The disappointing outcome from the CheckMate -914 trial undermines BMS’ hopes of moving PD-1 inhibitor Opdivo (nivolumab) and CTLA4 inhibitor Yervoy (ipilimumab) treatment into earlier-stage cancers.
AbbVie reports 4.5% rise in Q2 2022 net revenues
Pharmaceutical Technology
AUGUST 1, 2022
AbbVie has reported net revenues of $14.6bn for the second quarter (Q2) of 2022 as against $14bn in the year-ago quarter, indicating a 4.5% rise on a GAAP basis. Net revenue surged by 6.1% on an operational basis during the quarter. The GAAP diluted earnings per share (EPS) for the quarter ended 30 June grew by 21.4% to 0.51 from $0.42 in Q2 2021. An 11.2% surge in adjusted diluted EPS of $3.37 was reported in Q2 this year against $3.03 in the prior-year quarter.
What the FDA's New Dosage Guidance Means for the Future of Clinical Research
Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist
What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.
Modular Content: a Q&A with Mubasher Hassan, Global Head of Content Management, Grünenthal
PharmExec
AUGUST 1, 2022
A modular content strategy enables better processes, better governance, and better digital asset management.
ViiV agrees to expand access to long-acting HIV PrEP
European Pharmaceutical Review
AUGUST 1, 2022
ViiV Healthcare and the Medicines Patent Pool (MPP) have signed a new voluntary licensing agreement to increase access to cabotegravir long-acting (LA) for HIV pre-exposure prophylaxis (PrEP) in least developed, low-income, lower middle-income and Sub-Saharan African countries. Through this agreement, selected generic manufacturers will have the opportunity to develop, manufacture and supply generic versions of cabotegravir LA for PrEP in 90 countries, subject to required regulatory approvals be
GreenLight and US NIH partner to develop Covid-19 vaccine for variants
Pharmaceutical Technology
AUGUST 1, 2022
GreenLight Biosciences has entered a partnership with the US National Institutes of Health (NIH) for the development of Covid-19 vaccines, which offer broader protection against new variants and with durable effects. The company will jointly design and analyse messenger ribonucleic acid (mRNA) Covid-19 vaccines in partnership with the NIH unit National Institute of Allergy and Infectious Diseases’ Vaccine Research Center (VRC).
GCP update: advice on what to expect and how to prepare
Outsourcing Pharma
AUGUST 1, 2022
With updates to the Guideline for Good Clinical Practice Advancements on the horizon, an industry expert offers some perspective on what might be ahead.
5 Reasons to Upgrade Your Pharmacy Management Software
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Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.
Rosuvastatin Linked to Signs of Kidney Damage
Pharmacy Times
AUGUST 1, 2022
Compared to atorvastatin, rosuvastatin was associated with higher risks of blood in the urine and kidney failure that requires replacement therapy.
Curavit, Swing team up on fibromyalgia therapeutic trial
Outsourcing Pharma
AUGUST 1, 2022
The CRO and DTx specialist are joining forces to conduct a hybrid clinical trial of a potential digital therapeutic that is aimed at treating fibromyalgia.
Q&A With David Jimenez, President of Janssen Immunology
PharmExec
AUGUST 1, 2022
Jimenez discusses bringing care to diverse and underserved communities.
The Future of Treating AML
Pharmacy Times
AUGUST 1, 2022
The panel concludes with their thoughts on the future of the AML treatment landscape.
US Government Purchases 66 Million Doses of Moderna’s COVID-19 Booster Candidate
Pharmaceutical Commerce
AUGUST 1, 2022
Price tag for bivalent dose was $1.74 billion.
Ustekinumab Approved to Treat Pediatric Patients With Active Psoriatic Arthritis
Pharmacy Times
AUGUST 1, 2022
Ustekinumab is the first and only biologic that targets both cytokines interleukin (IL)-12 and IL-23.
A Message From Alex August 2022
Oswald's
AUGUST 1, 2022
Once again, it’s what we all seem to say at the beginning of every month—it’s August already!? July flew by here at the pharmacy. Early in the month, I traveled to Washington D.C. for an annual independent pharmacy trade show. The first time it’s been held in person since 2019. No surprise there! The focus… The post A Message From Alex August 2022 appeared first on Oswald's Pharmacy.
Oncology Overview: Investigational Autologous TIL Immunotherapy LN-145 for Cervical Cancer
Pharmacy Times
AUGUST 1, 2022
Studies suggest novel immunotherapy may have efficacy as monotherapy and in combination with an anti-PD-1 immune checkpoint inhibitor.
August 2022 Promotions
Oswald's
AUGUST 1, 2022
The post August 2022 Promotions appeared first on Oswald's Pharmacy.
Daily OTC Pearl: Men’s Bladder Control
Pharmacy Times
AUGUST 1, 2022
Men’s Bladder Control supplements promote bladder and prostate health.
Data analytics hiring levels in the pharmaceutical industry dropped in July 2022
Pharmaceutical Technology
AUGUST 1, 2022
The proportion of pharmaceutical companies hiring for data analytics related positions dropped in July 2022 compared with the equivalent month last year, with 64.8% of the companies included in our analysis recruiting for at least one such position. This latest figure was lower than the 68.8% of companies who were hiring for data analytics related jobs a year ago and a decrease compared to the figure of 69.7% in June 2022.
Daily Medication Pearl: Phentermine and Topiramate ER (Qsymia)
Pharmacy Times
AUGUST 1, 2022
Phentermine and Topiramate ER (Qsymia) is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management.
Novasep-PharmaZell commits nearly$7.5m to boosting API capacity
Outsourcing Pharma
AUGUST 1, 2022
The contract development and manufacturing organization plans to invest â7.3m to expand and upgrade API production capacity at its Mourenx, France facility.
Study: Metronidazole Desensitization Effectively Treats Patients with Hypersensitivity Reactions
Pharmacy Times
AUGUST 1, 2022
Patients with past medical histories of immunoglobulin E-mediated hypersensitivity reactions to metronidazole and other antimicrobial agents may receive safe and effective treatment using desensitization protocols.
Ipsen makes TCR play, grabbing two I-O therapies from Marengo
pharmaphorum
AUGUST 1, 2022
Ipsen has joined the ranks of companies working on T cell receptor (TCR) therapies for cancer, paying $45 million upfront for rights to early-stage candidates developed by US biotech Marengo Therapeutics. The French pharma group has also promised around $1.6 billion in back-end payments under the terms of the deal, which focuses on a pair of preclinical TCR therapies arising out of Marengo’s elective T Cell Activation Repertoire (STAR) platform.
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