Wed.May 24, 2023

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Fourth Dose of COVID Vaccine Produced Milder Symptoms In Patients With IBD

Drug Topics

Data presented at Digestive Disease Week show that patients with IBD had less intense post-vaccination symptoms after a fourth dose.

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STAT+: Addiction treatment center founder indicted in sprawling fraud scheme

STAT

Over the last few years, Daniel Cleggett Jr. appeared to be living a charmed life. The founder of a small Boston-area   addiction treatment empire knew he was under scrutiny; the Globe and STAT News  published investigations  in 2017 and 2019 into his questionable business dealings, and the Massachusetts attorney general’s office announced   shortly after that   it was examining alleged scams involving addiction treatment.

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Sulbactam-Durlobactam for Bacterial Pneumonia Gets FDA Approval

Drug Topics

The antibiotic, marketed as Xacduro, is indicated for hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) caused by susceptible strains of bacteria called Acinetobacter baumannii.

Hospitals 468
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Pharmacists are Overworked, Frustrated, and Unintentionally Absent from Patient Care: It’s Time to Rightsize the Role

Pharmacy Times

Specialty pharmacists—those caring for patients with serious, sometimes life-threatening conditions such as cancer or rheumatologic disease—are not immune from the ongoing labor crisis.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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What Is The Link Between Antidepressants and Hospital-Acquired Clostridium Difficile Infection?

Drug Topics

Researchers found an increased occurrence of CDI in individuals who were prescribed antidepressants.

Hospitals 464
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Startup Florence acquires Zipnosis from Bright Health to build out telehealth services

Fierce Healthcare

Startup Florence acquires Zipnosis from Bright Health to build out telehealth services hlandi Wed, 05/24/2023 - 06:15

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Physicians, Staff Express Negative Attitudes Toward Emergency Department-Initiated Buprenorphine Use

Pharmacy Times

The attitudes of community-based opioid use disorder treatment center staff toward the emergency department as a site of initiation were varied, with some feeling that emergency department-initiated buprenorphine may attract patients who were not experiencing life-threatening emergencies.

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FDA Approves Buprenorphine Extended-Release Subcutaneous Injection for OUD

Drug Topics

This treatment is the first and only long-acting buprenorphine injectable with weekly and monthly doses.

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Epic is going all in on generative AI in healthcare. Here's why a handful of health systems are eager to test-drive it

Fierce Healthcare

Epic is going all in on generative AI in healthcare.

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Bringing the Buzz: Public Relations Strategies to Increase Your Pharmacy’s Reach

Drug Topics

Writing op-eds, speaking at community centers, and participating in local 5K events are just a few ways to generate buzz about your pharmacy–for free.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Woman of the Week: Cognition Therapeutics’ Lisa Ricciardi

PharmaVoice

As CEO of the neurogenerative company, Ricciardi is applying her decades of “human capital” to advance Alzheimer’s and dementia treatments.

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FDA Approves Braeburn’s Brixadi Injection to Treat Moderate-to-Severe Opioid Use Disorder

Pharmacy Times

The drug is available in 2 formulations, including a weekly injection with a lower dose than previously available as well as a monthly injection.

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The cell ‘atlasing’ approach pushing the limits of drug discovery

PharmaVoice

Vizgen’s CEO discusses the potential of spatial genomics in the life sciences and the company’s role in the movement.

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Comprehensive Review Suggests Cranberry Juice, Supplements Can Prevent Repeat UTIs

Pharmacy Times

The preventive effect is believed to be a result of compounds unique to cranberries called proanthocyanidins.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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LGBTQ+ dating app Grindr helps fight a COVID-related decrease in STI testing

Fierce Healthcare

LGBTQ+ dating app Grindr helps fight a COVID-related decrease in STI testing aburky Wed, 05/24/2023 - 20:08

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Interventions for Heart Failure Should Span Care Continuum

Pharmacy Times

Comprehensive in-hospital planning, postdischarge follow-up, ongoing support are key.

Hospitals 123
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Opinion: What if we’re talking about teens’ mental health too much?

STAT

Every day, it seems, is mental health awareness day. In the U.S., there’s Eating Disorders Awareness Week in February. May is National Mental Health Awareness Month, which includes National Children’s Mental Health Awareness Day. September is Suicide Prevention Awareness Month and in October we go global, with  World Mental Health Day.

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Dupilumab Is the First Investigational Biologic to Significantly Improve Lung Function in Patients With COPD

Pharmacy Times

The treatment improved lung function at 12 weeks and quality of life at 4 weeks.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Biopharma staffers exhausted and susceptible to burnout, report says

Fierce Pharma

Biopharma staffers exhausted and susceptible to burnout, report says kdunleavy Wed, 05/24/2023 - 16:52

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Linked Immunization Information System, Claims Data Captured COVID-19 Vaccination Status Better Than Claims Data Alone

Pharmacy Times

Reporting vaccination data to Immunization Information Systems databases can support public health surveillance activities.

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PCMA slams lawmakers for lack of PBM voices at hearing on industry

Fierce Healthcare

PCMA slams lawmakers for lack of PBM voices at hearing on industry pminemyer Wed, 05/24/2023 - 16:35

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Ketamine is comparable to ECT for patients with treatment-resistant depression, study shows

STAT

When seriously depressed patients don’t respond to antidepressants, the alternatives are limited. Now a new study has found that ketamine performs at least as well as the current gold standard for such patients, electroconvulsive therapy (ECT), suggesting it deserves consideration as a frontline response for people with treatment-resistant depression.

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First redosable gene therapy approved

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved the first-ever redosable gene therapy for the rare skin disease dystrophic epidermolysis bullosa (DEB). VYJUVEK (beremagene geperpavec-svdt) is authorised for DEB patients six months of age or older. The gene therapy is a topical gel that restores functional copies of the COL7A1 gene to provide wound healing and sustained functional COL7 protein expression with redosing.

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With Medicaid redeterminations underway, many are unaware of the process: KFF

Fierce Healthcare

With Medicaid redeterminations underway, many are unaware of the process: KFF pminemyer Wed, 05/24/2023 - 16:07

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We’ll soon have tools to protect infants against RSV. Can we put them to good use?

STAT

When scientists, physicians, and public health officials discuss RSV, the talk almost always turns to babies. This ubiquitous infection can leave small children, especially infants, struggling to breathe. It petrifies parents. When RSV season hits, children’s hospitals are slammed by a surge in sick baby admissions.

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AI-based infectious disease detector gets UK funding

pharmaphorum

AI-based infectious disease detector gets UK funding Phil.

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FDA Grants Approval to Vyjuvek, the First Ever Redosable Gene Therapy

PharmExec

Treatment to support patients with dystrophic epidermolysis bullosa.

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STAT+: FDA delays decision on Sarepta’s gene therapy for Duchenne muscular dystrophy

STAT

The Food and Drug Administration is delaying by one month a decision on the approval of a gene therapy for Duchenne muscular dystrophy, the treatment’s maker, Sarepta Therapeutics, said Wednesday. Sarepta said the FDA expects to complete the review of its gene therapy called SRP-9001 by June 22. A decision had been expected on or before May 29.

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Untangling the Complexities of Cell and Gene Therapy Clinical Trials: A Supply Chain Perspective 

Pharmaceutical Technology

By Luisa Sterkel & Joana Loureiro , Tenthpin Consultants The promise and potential of cell and gene therapies (CGT) has emerged in the recent past and currently over 1.500 CGT are registered for clinical trials holding great hope for the treatment of challenging and uncurable diseases. The ability to modify or introduce genetic material in human cells in such a precise and patient-centered manner clearly constitutes a breakthrough in personalized medicine.

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STAT+: Congress took on high drug prices in Medicare. Now Biden wants to take it to Medicaid

STAT

WASHINGTON — The Biden administration wants to help states control Medicaid prescription drug costs by making prices more transparent and curbing the practice of so-called spread pricing. The goal is to give states more leverage in price negotiations by forcing drugmakers to share and publish details about their pricing data. The government would collect specific drug pricing information from makers of up to 10 particularly high-cost drugs.

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NACDS commends House committee for inclusion of PBM reform bill in PATIENT Act

Drug Store News

NACDS said this action is an essential component of PBM reform in the Medicaid program and vital for patients and the pharmacies serving them.

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Opinion: How ‘screen and refer’ systems fail to help patients

STAT

We’ve all had the experience of a doctor or other health care worker staring at screen while asking us sensitive questions to fill out our electronic health records. But that frustrating experience is made even worse by a new trend in health care. As Sanjay Basu wrote in a recent First Opinion, hospitals are using so-called “screen and refer” systems to identify people with social needs, like those who are experiencing domestic violence or hunger.

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Five proposed biosimilars planned for development in Europe

European Pharmaceutical Review

Alvotech and Advanz Pharmaceutical have extended their partnership, regarding the supply and commercialisation of five proposed biosimilars in Europe. “We are very excited to extend our existing partnership with Advanz Pharma into additional therapeutic areas… to provide better patient access to more affordable biologics,” stated Robert Wessman, Chairman and CEO of Alvotech.