Fri.May 24, 2024

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Diagnostic Accuracy, Antibiotic Use Must Be Improved in C. Diff Infections

Drug Topics

In an abstract presented at Digestive Disease Week 2024, researchers analyzed Clostridioides difficile episodes and identified the risk factors and potential medications that caused them.

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Study Finds Semaglutide Improves Chronic Kidney Disease in Patients With Type 2 Diabetes

Pharmacy Times

The role of semaglutide as a glucagon-like peptide-1 (GLP-1) receptor antagonist could offer further treatment options to improve patient outcomes.

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Podcast: Litigation Lawyer on PBMs and Defending Independent Pharmacies

Drug Topics

Experienced litigation lawyer Mark Cuker sat down with Drug Topics to discuss pharmacy benefit managers and their often corrupt practices.

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New evidence supports fear that drinking raw milk containing bird flu viruses may be dangerous

STAT

A new study published Friday provides more evidence of the potential danger of drinking unpasteurized, or raw, milk containing H5N1 avian flu viruses. The work , published in the New England Journal of Medicine, showed that mice that were fed milk from H5N1-infected cows became very ill.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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FDA Roundup: Eyela Biosimilars, Belimumab Autoinjector

Drug Topics

Check out important updates from the FDA for the week of May 20.

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Pharmacy Closures Spark Need for PBM Reform

Pharmacy Times

Multiple states have enacted legislation to rein in PBM practices

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More Trending

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Pharmacists in Medical Cannabis Care Models: A Review

Pharmacy Times

As medical cannabis use grows, pharmacist involvement is essential.

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Therapeutic areas where competition is heating up in pharma

PharmaVoice

The stage is set for potential blockbuster-level showdowns targeting these high-growth indications.

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Thinking Outside The Pill Bottle: Forging Your Own Path

Pharmacy Times

By venturing beyond the traditional, you can not only shape your own fulfilling career, but also contribute to the future of pharmacy practice and improve patient care for generations to come.

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STAT+: Nursing homes sue over Biden administration’s minimum staffing rule

STAT

A new federal lawsuit challenging the Biden administration’s new minimum nursing home staffing rule lays out the worst-case scenario: Hundreds of long-term care facilities forced to downsize or close, tens of thousands of vulnerable seniors displaced, and countless others waiting longer for care. Not only that, the complaint argues that the Centers for Medicare and Medicaid Services lacked the authority to implement the final rule.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Palliative Care and Harm Reduction: Improving Outcomes for Patients With Cancer, SUD

Pharmacy Times

Speakers at the 2024 Society of Pain and Palliative Care Virtual Conference discussed advanced treatment opportunities for patients with substance use disorder (SUD) and cancer-related pain.

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This week in clinical trials: 20th to 24th May

pharmaphorum

Exciting advancements in the world of clinical trials - Arecor Therapeutics, Faron, AstraZeneca, Volta Medical, J&J, Pneumagen, and Nimbus Therapeutics make headlines. Dive into this week's top stories impacting the future of medicine.

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STAT+: After MDMA therapy, she considered suicide. The trial data tell a different story

STAT

The MDMA study was her last hope. She had read headlines celebrating a 83% response rate in one small, early study of the psychedelic for treating PTSD, and was counting on the new clinical trial to alleviate her own post-traumatic stress disorder. Instead, after her first MDMA session, she felt intense despair when her symptoms didn’t dissipate.

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ASCO: AffyImmune claims a first with CAR-T for solid tumours

pharmaphorum

AffyImmune Therapeutics has recorded what it says is the first documented complete response in a patient with a solid tumour treated with CAR-T therapy. The case comes from a phase 1 study of its ICAM-1 targeting CAR-T autologous candidate AIC100 in patients with relapsed/refractory poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC), which will be reported at the ASCO congress next week.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Opinion: Pandemic lessons must spur federal action to protect nursing home residents

STAT

About one-third of Americans who reach age 65 will need nursing home care in their lifetimes — which can be a daunting thought if you recall the suffering of residents as the Covid-19 pandemic exposed long-standing problems in nursing homes. These problems did not fade away with the end of the public health emergency, and nursing home residents continue to be disproportionately affected by Covid-19.

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NICE, NHS England unveil new pathway for medtech

pharmaphorum

NICE and NHS England are seeking feedback on proposed new rules and commissioning principles for medtech products.

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Weight-loss jabs shouldn’t be quick-fix solution for governments, says expert

The Guardian - Pharmaceutical Industry

Obesity prevention is cheaper long-term option, says Cambridge professor, with focus on dietary advice and exercise plans Skinny jabs risk being used as a cop-out by governments to avoid making hard policy choices to prevent obesity, a leading expert has warned. Prof Giles Yeo, a geneticist at the University of Cambridge and expert on obesity and the brain control of food intake, said drugs such as semaglutide – the active ingredient in the weight-loss jab Wegovy – were remarkable and worked for

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ASCO: Merus bispecific garners attention after abstract drop

pharmaphorum

Shares in Merus spike on ASCO abstract on phase 2 trial of EGFRxLGR5 bispecific petosemtamab in head and neck cancer.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Opinion: STAT+: Unmasking the ‘centricity’ illusion in clinical trials

STAT

During my 25 years working in clinical trial operations, I’ve seen the biopharmaceutical world talk a big game about making the process easier for the sites running the trials and the patients participating in them. Everyone from trial sponsors to the Food and Drug Administration has been quick to promise simpler processes, less hassle, and better experiences for everyone involved.

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ADC developer Pheon raises $120m, and other bio financings

pharmaphorum

This week’s round-up of biotech financings is led by a $120 million round for UK-based antibody-drug conjugate (ADC) developer Pheon, with SixPeaks also pulling in nine figures and smaller rounds for Progentos, LabGenius, and Grey Wolf, and Imvax.

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Can you take benzonatate with NyQuil?

The Checkup by Singlecare

You’ve heard that mixing medications can be dangerous. But when you have a nagging cough that’s keeping you up all night, it can be tempting to try a second treatment if the first doesn’t work. NyQuil , which contains acetaminophen , dextromethorphan, and doxylamine , is a popular over-the-counter (OTC) cough medicine and cold remedy that you probably already have in your medicine cabinet.

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Even after sharp sales drop, Pfizer sees bright side with priority review voucher from Paxlovid approval

Fierce Pharma

In a change of pace from the recent COVID-related business struggles for Pfizer, the drugmaker has picked up a valuable reward from the FDA in the form of a priority review voucher (PRV). | The FDA awarded the voucher based on Paxlovid's status as a countermeasure to a material medical threat, according to a notice in the Federal Register.

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FDA advisory committee reviews Novo Nordisk insulin icodec for T1D

Pharmaceutical Technology

The US FDA's EMDAC is set to hold a meeting to assess the benefit-risk profile of Novo Nordisk's insulin icodec, to treat type 1 diabetes.

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How does hydroxychloroquine work for Lupus?

The Checkup by Singlecare

Hydroxychloroquine is a generic prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat malaria, rheumatoid arthritis, and erythematosus lupus. It’s also sold under the brand name Plaquenil. Hydroxychloroquine is considered a first-line treatment for autoimmune inflammatory conditions such as lupus. It’s been shown to reduce lupus flare-ups and help prevent long-term damage from flares.

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New Phase III data for hidradenitis suppurativa biologic released

European Pharmaceutical Review

UCB has announced positive results from the first Phase III trials evaluating the efficacy and safety of an IL-17A and IL–17F inhibitor to treat adults with moderate-to-severe hidradenitis suppurativa. Humanised IgG1 monoclonal antibody (mAb) BIMZELX ® (bimekizumab-bkzx) selectively binds to IL-17A, IL-17F, and IL-17AF cytokines. This inhibits their interaction with the IL-17RA/IL-17RC receptor complex, UCB explained.

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How long does it take for meloxicam to start working?

The Checkup by Singlecare

Meloxicam is a prescription drug originally branded under the name Mobic. As a nonsteroidal anti-inflammatory drug (NSAID), it is prescribed for moderate to severe pain experienced from disorders such as osteoarthritis, rheumatoid arthritis, or juvenile rheumatoid arthritis. It may also be used in ankylosing spondylitis. Meloxicam is unique from other over-the-counter NSAID options in that it follows a different metabolic pathway that is less harmful to the gastrointestinal system.

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Elevance Health Foundation launches $10M effort to back small businesses to address equity

Fierce Healthcare

Elevance Health's philanthropic arm is launching a new initiative that aims to provide loans to small businesses and other organizations in a bid to address health equity. | Elevance Health's philanthropic arm is launching a new initiative that aims to provide loans to small businesses and other organizations in a bid to address health equity.

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Diazepam for dogs

The Checkup by Singlecare

Diazepam is a generic drug widely known by its brand-name version, Valium. Veterinarians use it in dogs to treat seizures, anxiety, and difficulty peeing due to tightening or obstruction of the urethra. They may also use it as a sedative before veterinary procedures that require anesthesia. Diazepam is a fast-acting sedative that belongs to the benzodiazepine family.

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Can Pharmacy Automation Help Solve the Industry’s Labor Shortage?

Pharmacy Times

As staffing pressures continue straining pharmacy operations, the right automation solutions offer a path to driving growth and maintaining safety standards, all while better utilizing current personnel.

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ASCO 2024: Merus touts positive Phase II data for head and neck cancer antibody

Pharmaceutical Technology

Shares in Merus rose by 15% in premarket trading, following the announcement of positive Phase II data to be presented at ASCO.

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Can you buy metformin over the counter?

The Checkup by Singlecare

Metformin hydrochloride is a generic drug approved by the Food and Drug Administration (FDA) to help manage blood sugar levels in people with type 2 diabetes mellitus. It can also be used off-label for weight loss. Healthcare providers typically prescribe metformin along with a healthy diet and regular exercise routine. Often referred to by its brand names Glucophage, Fortamet, and Glumetza, metformin is available as an oral tablet and oral solution.

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Closing the Gap: Addressing Underrepresentation of Women in Cardiovascular Clinical Trials

Pharmacy Times

Continued disparities of gender representation in cardiovascular research reveal oversights that impact adequate diagnosis and treatment of cardiovascular disease in women.

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King’s Doctoral Training Centre to investigate MS symptom management

Pharma Times

The lifelong autoimmune disease affects more than 150,000 people living in the UK

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