Tue.Oct 31, 2023

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Pfizer, BioNTech Release Positive Topline Data for Combination COVID-19/Flu Vaccine

Drug Topics

The combination vaccine produced robust immune responses from vaccine candidates in a phase 1/2 clinical trial.

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Roche’s $7B Roivant deal was a ‘moment of opportunity,’ CEO says

PharmaVoice

Roivant CEO Matt Gline and Telavant CEO Frank Torti know Roivant’s position as buyers and sellers in the pharma industry, and they’re embracing those opportunities.

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Addressing Challenges in Pediatric Tuberculosis Treatment

Drug Topics

Pediatric TB is an intricate challenge that demands continued attention and funding.

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Physical Activity Positively Impacts Symptoms of Depression, Anxiety

Pharmacy Times

Modern society has put individuals at an increased risk of dopamine overload, causing an increase in mental health disorders.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Health Care Workers Can be Part of the Climate Change Solution

Drug Topics

Anesthetic gases and meter dose inhalers, how we use our antibiotics, how we use our resources for infection prevention and control, and how we use plastic and food in our hospitals all add up.

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STAT+: Tracking the FDA advisory panel on the first CRISPR-based treatment for sickle cell disease

STAT

The Food and Drug Administration is convening a meeting of outside experts on Tuesday to review exa-cel, a CRISPR-based treatment for sickle cell disease made by Vertex Pharmaceuticals and CRISPR Therapeutics. Tuesday’s meeting is set up a bit differently than most FDA advisory panels. The agency has not raised any concerns about exa-cel’s efficacy or safety, and there will not be a typical vote at the end of the day on whether the data from exa-cel’s pivotal clinical trial

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Opinion: I lost my son to OxyContin. ‘The Fall of the House of Usher’ is my Sackler revenge fantasy

STAT

Editor’s note: This essay contains spoilers for the Netflix show “The Fall of the House of Usher.” “W atch “ The Fall of the House of Usher” on Netflix when you can. F**cking Great! Totally based on the Sacklers—Fictional obviously but so damn good!

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Assessing Impact of CGM on Progression of Coronary Atherosclerosis in Patients With T2D

Drug Topics

The OPTIMAL trial assessed the effects of continuous glucose monitoring compared with HbA1c-guided glycemic control on the progression of coronary atherosclerosis in patients with type 2 diabetes mellitus.

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STAT+: Eli Lilly to pay $200 million for Beam’s share of drugs from gene-editing firm Verve

STAT

Eli Lilly said Tuesday that it will pay $200 million to gene-editing firm Beam Therapeutics for Beam’s stake in Verve Therapeutics, another gene-editing company focused on treatments for heart disease. The deal, which also includes future milestone payments, is evidence that despite the pressure on biotechnology stocks there is still interest in very early cutting-edge technologies among big pharmaceutical players.

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FDA Approves sBLA for Abatacept in the Treatment of Juvenile Psoriatic Arthritis

Pharmacy Times

The approval is supported by safety data from clinical trials assessing abatacept in the treatment of patients aged 2 to 17 with psoriatic arthritis.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: DeepMind touts AlphaFold’s new skills as protein-folding AI models face off

STAT

On Tuesday, Google DeepMind and Isomorphic Labs announced a significant progress update on the next iteration of AlphaFold, the deep learning model that in 2020 cracked the problem of predicting a protein’s structure from its amino acid sequence, leapfrogging other approaches in computational biology. Now, the companies say they have developed the model to predict not just standalone protein structures, but what proteins look like in combination with several classes of molecules, includin

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Once a high-flying 'unicorn,' Olive AI sells two key businesses, winds down operations

Fierce Healthcare

Healthcare startup Olive saw a meteoric rise in 2020 and 2021, spurred by the digital health funding boom and the need for automation during the COVID-19 pandemic. | It marks the end of the line for healthcare automation startup Olive AI. The company sold its clearinghouse and patient access business units to Waystar and its prior authorization business unit to Humata Health.

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La ‘paradoja hispana’ intriga a una nueva generación de investigadores decididos a resolverla

STAT

Read in English | Leer en inglés. D urante 40 años, los investigadores han intentado sin éxito explicar –o desacreditar– la “paradoja hispana”, es decir, la constatación de que los hispanoamericanos viven varios años más que los estadounidenses blancos por término medio, a pesar de disponer de ingresos y atención sanitaria mucho menores, y mayores tasas de diabetes y obesidad.

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Review Treatment Options for Insomnia

Pharmacy Times

According to 2020 data from the CDC, about 14.5% of adults reported having trouble falling asleep most or every day during the 30 days prior to the survey.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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How skeptical should you be of an after-the-fact subgroup analysis in a failed clinical trial?

STAT

This article was adapted from STAT’s latest report , “Subgroup analysis: how to evaluate post hoc tests for significance in failed clinical trials.” C linical trials of newly developed drugs often don’t work out.

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Nearly a quarter of hospital stent procedures are unnecessary, fueling billions in low-value spending, Lown Institute finds

Fierce Healthcare

Nearly a quarter of hospital stent procedures are unnecessary, fueling billions in low-value spending, Lown Institute finds dmuoio Tue, 10/31/2023 - 14:33

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New CDC campaign asks health care leaders to take responsibility for reducing burnout

STAT

Often, workplace conversations about burnout put the onus on the individual to take care of their mental health while ignoring management’s role in solving the problem. A new anti-burnout campaign from the Centers for Disease Control and National Institute for Occupational Safety and Health avoids this typical — and often frustrating — tactic, instead imploring leaders to better support health care workers.

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Wisp’s ‘bold and unapologetic approach’ to women’s sexual and reproductive health

PharmaVoice

In the role of interim CEO of Wisp, Monica Cepak aims to break down barriers and expand access via telehealth.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Medicare is urged to consider Amgen patent maneuvers when negotiating the price for a drug

STAT

As Medicare prepares to negotiate prices for its first batch of medicines, an advocacy group argues the agency should factor in controversial patent maneuvers for one drug that will have cost the program nearly $2 billion in additional spending by 2026. At issue is the Enbrel medication sold by Amgen for treating rheumatoid arthritis and other ailments.

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Cleveland Clinic to launch prescription delivery via drone in 2025, starting with specialty and rush medications

Fierce Healthcare

Cleveland Clinic plans to launch a drone delivery service to bring certain medications directly to patients’ homes, starting in 2025. | Cleveland Clinic plans to launch a drone delivery service to bring certain medications directly to patients’ homes, starting in 2025.

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Rite Aid offers After Work Wednesday walk-in clinic

Drug Store News

Customers and their families can conveniently get routine immunizations at select Rite Aid locations.

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CDC releases free tools for hospitals to address their workers' mental health

Fierce Healthcare

The Centers for Disease Control and Prevention (CDC) has launched the first-ever federal campaign encouraging hospitals to track and address burnout across their workforces. | Included among the Impact Wellbeing campaign’s free offerings are a wellbeing questionnaire, a leadership storytelling guide and a toolkit for removing mental health questions from a hospital's credentialing applications.

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MHRA imposes restrictions on acne drug in children

pharmaphorum

MHRA imposes restrictions on acne drug in children Phil.

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Walmart celebrates re-grand opening of 117 remodeled stores

Drug Store News

Walmart's largest single-day rollout of re-grand openings is part of more than 700 store modernizations expected in 2023.

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Teamwork for Better Healthcare Solutions: Merging Clinical and Marketing Efforts

PharmExec

In the ever-evolving landscape of healthcare, it's vital for organizations to take steps toward bridging the gap between their clinical and marketing teams.

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Sarepta’s disappointing data put the FDA in a difficult spot

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, all. Damian here with disappointing news on a closely watched gene therapy, an interesting deal in genome editing, and the long shadow of biotech’s slump.

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Lilly buys Beam’s option on Verve drug programmes

pharmaphorum

Lilly buys Beam’s option on Verve drug programmes Phil.

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BJ’s Wholesale Club thanks members with free Thanksgiving turkeys

Drug Store News

From Nov. 1–9, members will be eligible to receive a digital coupon for a free fresh or frozen Butterball whole turkey when they spend $150 in the same transaction, in-club or online.

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Despite trial miss, Sarepta plans new filing for DMD therapy

pharmaphorum

Despite trial miss, Sarepta plans new filing for DMD therapy Phil.

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ArriVent’s lung cancer therapy gains FDA breakthrough therapy status 

Pharmaceutical Technology

ArriVent Biopharma has received the US FDA's breakthrough therapy designation for furmonertinib to treat non-small cell lung cancer.

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After period of decline, dementia may be on the rise again

pharmaphorum

After period of decline, dementia may be on the rise again Phil.

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Open enrollment on the ACA exchanges is set to begin. Here are 5 trends to watch

Fierce Healthcare

Open enrollment on the Affordable Care Act's (ACA's) exchanges is set to begin, but signing up for coverage remains confusing for many, a

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La Roche-Posay’s 'Healing Power of Touch' campaign supports cancer patients, caregivers

Drug Store News

In partnership with the Union for International Cancer Control, La Roche-Posay is launching a digital learning platform for cancer patients and caregivers.

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