Tue.Feb 11, 2025

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Can you take meloxicam for tooth pain?

The Checkup by Singlecare

Meloxicam , sold under the brand name Mobic, is a prescription nonsteroidal anti-inflammatory drug ( NSAID ) used to treat inflammatory conditions like rheumatoid arthritis and osteoarthritis. It is also used off-label (for a use not approved by the Food and Drug Administration) to treat ankylosing spondylitis. Meloxicam is a stronger painkiller than other NSAIDs like ibuprofen and naproxen.

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FDA Appears to Be Granting Zombie Rare Pediatric Disease Designations Waiting for the Rare Pediatric Disease Priority Review Voucher Program to be Revived

The FDA Law Blog

By Mark A. Tobolowsky & Frank J. Sasinowski The rare pediatric disease priority review voucher program remains in its sunsetting state the current authority only allows for granting of such vouchers if the drug was designated as a drug for a rare pediatric disease not later than December 20, 2024, and for which a rare pediatric disease product application is approved not later than September 30, 2026.

FDA
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Novartis nets potential first-in-class medicine in new cardiovascular acquisition

European Pharmaceutical Review

Novartis has agreed to acquire Anthos Therapeutics, Inc., and will gain rights to a potential first-in-class biologic. Anthos has been developing the monoclonal antibody abelacimab as a treatment to prevent stroke and systemic embolism in individuals with atrial fibrillation, under a license from Novartis. The therapy is designed to induce effective haemostasis-sparing anticoagulation through Factor XI inhibition, preventing the activated form (Factor XIa) being generated.

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HPM’s Larry Houck Presenting at WCF Opioid and Fentanyl Abuse Management Congress

The FDA Law Blog

By Larry K. Houck One of the most significant issues facing hospitals and other facilities is the diversion of controlled substances meant for patients by physicians, pharmacists, nurses and other trusted healthcare employees. Recent employee diversion of significant controlled substance quantities from hospitals has resulted in large civil monetary settlements, some in the millions of dollars, and costly compliance remediation programs to resolve allegations.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Weight Loss, Lipid Changes Could Point Towards Dementia Risk

Drug Topics

Poor cardiometabolic health is associated with cognitive impairment in later life, but there is no clear association between cardiometabolic trajectories and early markers.

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Guest Perspective: Prioritize Innovative Care

PhRMA

Conversations and healthy debate about issues facing our industry and the health care system are critical to addressing some of today’s challenges and opportunities. The PhRMA blog welcomes guest contributors, including patients, stakeholders, innovators and others, to share their perspectives and point of view.

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In the crowded cardio space, it’s David vs. Goliath for small biotechs

PharmaVoice

What will it take for a clinical-stage biotech to break into the cardio space? One CEO thinks he has the answer.

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New Drug Review: FDA Approves Tryvio for the Treatment of Hypertension in Combination With Other Antihypertensive Drugs to Lower Blood Pressure

Drug Topics

Tryvio was given FDA approval on March 19, 2024.

FDA
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Study: Vitamin D Status in Early Pregnancy and Infant Outcomes

Pharmacy Times

Pharmacists can recommend vitamin D supplements and vitamin D-rich foods to support healthy pregnancy outcomes.

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Non-Oral Therapies Have Made Significant Progress in Treating Shingles Pain

Drug Topics

Researchers conducted a review of clinical studies to better understand non-oral drugs for the treatment of pain related to herpes zoster.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Novartis signs agreement to acquire Anthos for $925m upfront

Pharmaceutical Technology

Novartis has agreed to acquire Anthos Therapeutics, a Boston-based clinical-stage biopharmaceutical company, for an upfront payment of $925m.

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OTC Roundup: Digestive Health Products

Drug Topics

Help your patients overcome tummy troubles with trusted OTC products that relieve bloating, heartburn, and more, promoting smooth and happy digestion.

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Obesity market to reach $173.5 billion by 2031

Pharmaceutical Technology

Given the number of comorbidities associated with obesity, the market's growth will impact the entire cardiometabolic disease space.

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Social Media Could Be Utilized for Self-Care Messaging, Diabetes Education

Drug Topics

Social media can help close the gap on health care information access, but pharmacists still play a large role in diabetes management, especially in therapeutics.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Repatha side effects and how to avoid them

The Checkup by Singlecare

Repatha is the brand name for evolocumab, an FDA-approved monoclonal antibody used to lower cholesterol. In addition to lowering LDL (low-density lipoprotein) cholesterol levels, Repatha helps restore blood flow to the heart, decreasing the risks of heart attack and strokes in people with heart disease. Repatha is often used when medications like statin drugs dont lower cholesterol enough and can be combined with statin medications.

FDA
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SARS-CoV-2 Infection Associated With Increased Plaque in Coronary Arteries, Higher Risk of Cardiac Events

Pharmacy Times

Emerging data indicate that COVID-19 is also characterized by inflammation present in the heart and other organs

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Can you take gabapentin and melatonin together?

The Checkup by Singlecare

Individual medications are sometimes taken together to increase their positive effects: Tylenol (acetaminophen), aspirin, and caffeine, for example, is a well-known combination that can treat migraine pain better and faster than taking a single pain reliever. But you may not be as familiar with the combination of gabapentin and melatonin. At first glance, these two drugs dont seem to have much in common.

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Expert: Pharmacists, Care Team Play Crucial Role in Optimizing IVIG Therapy for CIDP

Pharmacy Times

Richard Lewis discusses the critical role pharmacists and health care providers play in ensuring safe administration of IVIG for patients with CIDP.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Novartis builds in cardiovascular with $3.1bn Anthos buy

pharmaphorum

Novartis has agreed to buy Anthos from private equity firm Blackstone for $3.1 billion, taking Factor XI inhibitor abelacimab back in-house.

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Two biotech companies claim they use AI to design drugs from scratch. Do they?

STAT

Absci and Generate say they use AI to make drugs. Do they?

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FDA Approves Mirdametinib for Treatment of Adults, Children With NF1-PN

Pharmacy Times

The approval is based on positive clinical trial results that indicated deep and durable reductions in plexiform neurofibroma.

FDA
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WHO and St Jude start distributing paediatric cancer medicines amid US aid cuts

Pharmaceutical Technology

The World Health Organization and St Jude Children's Research Hospital have kicked off a programme to distribute cancer medicines to LMICs.

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Fierce Healthcare - Untitled Article

Fierce Healthcare

Humana posted a $693 million loss in the fourth quarter of 2024, a notable increase from its $541 million loss in the prior-year quarter, according to its earnings report released Tuesday morning.

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Lactate is a Key Regulator of Immune Escape, Bone Marrow Fibrosis in Myelofibrosis

Pharmacy Times

Circulating lactate is increased in patients with myelofibrosis and corresponds with the remodeling of lactate export channel monocarboxylate transporter 4, suggesting a link with fibrosis establishment.

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Ozempic side effects in females

The Checkup by Singlecare

Ozempic (semaglutide) is an injectable medication approved by the U.S. Food and Drug Administration (FDA) to treat Type 2 diabetes mellitus and lower the risk of heart attack or stroke in people with Type 2 diabetes and cardiovascular disease. Healthcare providers may also use Ozempic injectables off-label for weight loss management. It falls under the drug classes of antidiabetics and GLP-1 agonists.

FDA
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UK health insurer Vitality to offer members discounted anti-obesity drugs

The Guardian - Pharmaceutical Industry

Third-largest healthcare insurer will be first to give 20% off treatments such as Wegovy and Mounjaro through health cover Vitality has become the first health insurer in the UK to offer customers discounted weight loss treatments for up to a year through its health cover. The UKs third-largest health insurer behind Bupa and Axa, with 1.9 million members, said it would offer discounts of up to 20% for medications such as Wegovy and Mounjaro which are popular but pricey to members, based on the

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Vertex pain pill dominates earnings call discussion

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning. Let’s get straight into another busy news day.

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Ten years on, Roche jettisons InterMune and Esbriet

pharmaphorum

It's been 10 years since Roche bought InterMune for $8.3bn on the promise of its pulmonary fibrosis drug Esbriet.

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For Pharmacists Treating Thalassemia, Monitoring Anemia and Proper Counseling on Therapies is Crucial

Pharmacy Times

Thalassemia, a chronic blood condition that reduces hemoglobin levels, requires a hands-on approach from pharmacists in patient monitoring and diagnosis.

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Looking beyond the scale: Why measures of physical activity should be incorporated into obesity trials to support long-term sustainable weight loss

pharmaphorum

Looking beyond the scale: Why measures of physical activity should be incorporated into obesity trials to support long-term sustainable weight loss Mike.

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Fierce Healthcare - Untitled Article

Fierce Healthcare

Walgreens must pay more than $987 million as part of an arbitration award won by a virtual care company, a federal judge ruled Monday. | Walgreens said it is closely evaluating its legal rights and options to challenge both the award and the amount of damages on appeal.

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Get Up To Speed on Medicare Inflation Rebates: HPM Issues Memorandum Summarizing CMS Final Rule; HPM and Riparian to Co-Host Webinar

The FDA Law Blog

By Alan M. Kirschenbaum & Sophia R. Gaulkin Drug manufacturers wont be receiving their first invoices for Medicare Part B and Part D inflation rebates until later this year, but rebates have been accruing since first quarter 2023 for Part B rebates and October 2022 for Part D rebates. To help our readers learn more about these rebates before they confront the first invoices, weve prepared a memo summarizing CMS final rule on the two Medicare inflation rebate programs, which was issued on De

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Fierce Healthcare - Untitled Article

Fierce Healthcare

A new collaboration between three health plans is aiming to improve primary care in California and reduce physician burnout. | Blue Shield of California, Aetna California and Medi-Cal insurer Health Net are all participating in the California Advanced Primary Care Initiative.