What Impacts Adult Vaccination?
Drug Topics
OCTOBER 21, 2022
Adult vaccine uptake lags and understanding the reasons could be important.
Fri.Oct 21, 2022
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What’s keeping pharma leaders up at night
PharmaVoice
OCTOBER 21, 2022
C-suite execs in the life sciences share their late-night thoughts including innovation, patient access and market factors.
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Vaccine Hesitancy Trends from 2019 to 2022 Evaluated
Drug Topics
OCTOBER 21, 2022
As vaccine hesitancy grows, fewer children are receiving routine childhood vaccines.
12 Things Pharmacy Students Can Do to Become Leaders
Pharmacy Times
OCTOBER 21, 2022
Small choices during pharmacy school can help students on the path to becoming leaders in the field.
From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Impact of the SARS-CoV-2 Omicron Variant on COVID-19 Reinfection Rates
Drug Topics
OCTOBER 21, 2022
The Omicron variant radically changed reinfection rates.
Study: PrEP Does Not Cause Shift in Vaginal Microbial Communities
Pharmacy Times
OCTOBER 21, 2022
Investigators examined the impact of daily oral tenofovir disoproxil fumarate in combination with emtricitabine to see the effect on the microbiota in South African women.
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Psychedelic Medicine May Offer a Better Solution to Overcoming Alcoholism
Pharmacy Times
OCTOBER 21, 2022
The benefits of psychedelic medicine could expand into long-lasting and transformative therapeutics to treat depression better than selective serotonin reuptake inhibitors (SSRIs).
Antibiotics Overprescribed to Hospitalized Children with COVID-19
Drug Topics
OCTOBER 21, 2022
Although few cultures showed bacterial coinfections, many children were given antibiotics.
Experts Discuss the Growing Role of Pharmacy Technicians During COVID-19
Pharmacy Times
OCTOBER 21, 2022
In a panel, pharmacy technicians across the world discuss how the role for pharmacy technicians will continue to grow post-pandemic in United States, Portugal, and the United Kingdom.
Bivalent mRNA COVID-19 Booster Associated With Significantly Higher Antibody Response
Drug Topics
OCTOBER 21, 2022
Moderna’s bivalent mRNA COVID-19 booster reached prespecified superiority and noninferiority criteria against multiple strains of SARS-CoV-2.
Position Your Pharmacy for Expansion
Speaker: Chris Antypas and Josh Halladay
Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.
Could SIBO Be Preventing Your Remission from Hashimoto’s?
The Thyroid Pharmacist
OCTOBER 21, 2022
Many people with Hashimoto’s feel significantly better when they remove reactive foods, replenish nutrient depletions with restorative foods and supplements, and support the gut with probiotics. But what if those steps alone don’t work? You’ll have to dig a bit deeper. It took more than the implementation of the strategies above for me to resolve all my symptoms related to Hashimoto’s.
Patient Advocacy: The Cycle of Paying it Forward
Drug Topics
OCTOBER 21, 2022
A look at how a pharmacist's local CPESN network, the Pennsylvania Pharmacists Care Network, and Flip the Pharmacy, helped one pharmacy better serve patients.
Reexamining the Use of Tacrine for Neurological Diseases
Pharmacy Times
OCTOBER 21, 2022
Tacrine was originally brought to the market in 1993 as an acetylcholinesterase inhibitor to fight the symptoms of Alzheimer disease.
News Roundup: October 17 to October 21
Drug Topics
OCTOBER 21, 2022
Your weekly roundup of the latest news from Drug Topics®.
What the FDA's New Dosage Guidance Means for the Future of Clinical Research
Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist
What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.
Text message therapy for depression works in young adults
pharmaphorum
OCTOBER 21, 2022
Young adults with depression have been treated effectively with a cognitive behavioural therapy (CBT) course – delivered via text message – in a pilot study conducted by researchers in the US. The trial looked at a four-week CBT course adapted from a face-to-face programme to work via text messages, followed by a four-week follow-up period, in around 100 young adults in the US with at least one symptom of moderate depression and no recent history of antidepressant therapy.
Routine Vaccination Makes Chickenpox Rare in United States
Drug Topics
OCTOBER 21, 2022
The US was the first country to begin universal vaccination of children against varicella.
Hookipa partners with Roche for cancer immunotherapy development
Pharmaceutical Technology
OCTOBER 21, 2022
Hookipa Pharma and Roche have signed a strategic partnership and licence agreement for developing HB-700 and another undisclosed arenaviral immunotherapy. Under the deal, Hookipa will carry out research and initial clinical development through Phase Ib for HB-700 to treat KRAS-mutated cancers. On concluding this trial, Roche will gain the right to develop and market the licenced products across various indications, contingent on approval.
FDA’s vaccines chief sees possibility of more Covid boosters — sooner than he’d like
STAT
OCTOBER 21, 2022
Peter Marks, who leads the Food and Drug Administration’s vaccines operation, is still losing sleep over Covid. Yes, vaccines for all age groups have been authorized or approved. Yes, an updated vaccine is now available. And, yes, multiple products are in use and hundreds of millions of doses have been given in this country.
5 Reasons to Upgrade Your Pharmacy Management Software
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Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.
Make confident operational decisions by understanding your microflora
European Pharmaceutical Review
OCTOBER 21, 2022
The newest revision to regulatory guidance Annex 1 illustrates more stringent contamination control requirements; it is now a regulatory expectation for manufacturers to implement comprehensive and reliable contamination control strategies. Environmental monitoring (EM) programmes can help keep you compliant, measuring the state of control of production and ensuring product safety.
Opinion: Support family caregivers to improve and diversify clinical trials
STAT
OCTOBER 21, 2022
During the Covid-19 pandemic, America’s 53 million family caregivers gained some long overdue recognition for their vital role as unpaid extenders of an under-resourced health care workforce. The clinical trial enterprise, however, has yet to appreciate caregivers — and fully engage them — as critical partners in recruiting and supporting people who are older, disabled, or have Alzheimer’s disease, cancer, or other chronic medical conditions for research studies.
Study: Relaxation of Public Health Interventions for COVID-19 Has Strongest Impact on Children Aged 1 to 4 Years
Pharmacy Times
OCTOBER 21, 2022
Researchers suggest that winter 2020 to 2021 public health interventions lowered natural immunity in children and put them at greater risk of respiratory infection after restrictions were lifted.
STAT+: Inside Michelle McMurry-Heath’s departure from BIO: Firings, internal clashes, and a pivotal job review
STAT
OCTOBER 21, 2022
WASHINGTON — Only two years ago, Michelle McMurry-Heath was named chief executive of BIO, the world’s largest biotech trade organization. She was hailed by her predecessor as a “great leader.” So her swift and abrupt exit from the role earlier this month shocked the industry. But it was set in motion in late summer, when the Biotechnology Innovation Organization’s board of directors dispatched an outside firm to produce an “assessment” of her perf
GSK continues campaign for greater adult immunisation coverage
pharmaphorum
OCTOBER 21, 2022
The UK company reveals the results from a partner-led survey to discover the rates of vaccination for adults, why levels are lower than expected, and what can be done to improve this. Ben Hargreaves examines the reasons supplied by the survey and why GSK is invested in the answers. The emergence of COVID-19 meant that public awareness around vaccination and its importance in fighting the spread of infectious disease has increased rapidly.
STAT+: Up and down the ladder: The latest comings and goings
STAT
OCTOBER 21, 2022
Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others. That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.
Gilead and MacroGenics to develop bispecific cancer antibodies
European Pharmaceutical Review
OCTOBER 21, 2022
According to a new exclusive option and collaboration agreement between Gilead Sciences, Inc. and MacroGenics, Gilead will use MacroGenics’ DART® platform to develop MGD024, a potential therapy for blood cancers. MGD024 is a bispecific antibody that binds CD123 and CD3, a component designed to reduce CRS, a potentially fatal condition, while enhancing the intensity of antitumour activity with a longer half-life to allow dosing to be intermittent.
STAT+: Pharmalittle: Pfizer plans to quadruple price of its Covid-19 vaccine; pharma pushed to tie exec compensation to access to meds
STAT
OCTOBER 21, 2022
And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is rather modest so far. We plan to tidy up around the castle, visit with the Pharmalot ancestors, and promenade with the official mascot. And what about you? As we have noted previously, this is a fine time to rummage about pumpkin patches and apple orchards, or hop in your motor car to whiz through the countryside and enjo
Your endotoxin experts
European Pharmaceutical Review
OCTOBER 21, 2022
The future of sustainable Limulus amebocyte lysate (LAL) is here. The launch of Associates of Cape Cod, Inc.’s (ACC) PyroSmart NextGen ® recombinant Cascade Reagent (rCR) marks the introduction of a new sustainable recombinant LAL reagent technology for bacterial endotoxin testing (BET). There are other recombinant reagents on the market, but ACC’s is the only one that uses the same LAL cascade as traditional LAL reagents, while eliminating the potential for 1,3-?
STAT+: This summer’s Covid surge was bad for hospital profits
STAT
OCTOBER 21, 2022
This summer’s Covid-19 surge put a sizable dent in hospital finances, with two large investor-owned chains reporting lower revenue and profits in the recently-ended third quarter compared to the same period a year ago. Stocks in HCA Healthcare and Tenet Healthcare shed north of 10% and 30% of their value at times, respectively, on Friday following their underwhelming reports for the quarter, which ended September 30.
Methods for strain comparison and differentiation of environmental isolates
European Pharmaceutical Review
OCTOBER 21, 2022
NCIMB Ltd provides microbial identification services and curates The National Collection of Industrial, Food and Marine Bacteria – one of the culture collections that makes up the UK Biological Resource Centre Network. This culture collection dates back to 1950 1 and, given this history, it is no surprise that we occasionally find that a strain within it has been reclassified.
FDA Accepts New Drug Application for Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy
Pharmacy Times
OCTOBER 21, 2022
The treatment modulates the number of myosin heads that can enter “on actin” states and lowers the probability of force-producing (systolic) and residual (diastolic) cross-bridge formation.
AbbVie announces acquisition of DJS Antibodies for $255m
Pharmaceutical Technology
OCTOBER 21, 2022
AbbVie has announced the acquisition of UK-based biotechnology firm DJS Antibodies for nearly $255m in cash at closing. DJS focuses on the discovery and development of antibody therapies that act on difficult-to-drug disease-causing proteins, such as G protein-coupled receptors (GPCRs). The company leverages its HEPTAD platform to facilitate the antibody discovery of GPCRs and other difficult targets. .
Study: Adherence to PrEP Increases Prevention of HIV
Pharmacy Times
OCTOBER 21, 2022
However, lack of access and awareness about pre-exposure prophylaxis, medication cost, and underestimating disease risk are all barriers to PrEP.
Elements leading to a rational design of cyclodextrin-based formulations
European Pharmaceutical Review
OCTOBER 21, 2022
Cyclodextrins (CDs) principally belong to the field of supramolecular chemistry. 1 In their pharmaceutical application they are used as molecular containers (hosts) that can form inclusion complexes with drug compounds, according to the equilibrium for a 1:1 system: CD + compound ? CD-compound (1). which can be expressed quantitatively by the stability constant, K complex : K complex =.
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