European Pharmaceutical Review

JUNE 27, 2022

Downstream purification approaches. Due to their structural similarities, many current bsAb downstream purification methodologies are based on established mAb purification processes, using platform affinity, charge, hydrophobicity and mixed mode-based purification. Figure 1: Example of bi-specific formats.

Compounding 91

Compounding 91

European Pharmaceutical Review

JUNE 8, 2023

A study has reported for the first time, an innovative downstream method for mannosylerythritol lipids (MELs), were separated from the crude MEL mixture in a first stage with the other lipid derivatives (free fatty acids, mono- and diacylglycerols) removed by organic solvent nanofiltration (OSN).

69

69

European Pharmaceutical Review

FEBRUARY 24, 2023

#atccnews [link] pic.twitter.com/LF38xxYvWM — ATCC (@officialatcc) February 23, 2023 The solutions the organisations will launch together include: Genomic DNA from top cell lines used in bioproduction Measurement of cellular DNA left over following purification is required by regulatory authorities to ensure product safety.

77

77

European Pharmaceutical Review

DECEMBER 22, 2022

A delicate balance between the high-resource obligations of extensive testing and the importance of the choice means manufacturers are motivated to employ improved strategies for clone screening and characterisation at the earliest stages. Fortunately, high-throughput automated liquid handling purification platforms can be utilised.

Immunization 86

Immunization 86

ISPE

SEPTEMBER 11, 2023

12 , 28 , 29 , 30 , 31 Advantages SUT creates closed systems, which separates operators and rooms, enables aseptic transfer between containers, and mitigates the risk of cross-contamination. It also reduces environmental impact because it requires fewer chemicals and less high-purity water and heat.

Health and Personal Care Stores 52

Health and Personal Care Stores Vaccines Packaging Documentation 52

ISPE

MARCH 6, 2023

Using fewer resources to deliver the same or more output is inherent in pharmaceutical business practices. With rising global demand for energy, doing more with fewer resources is good for the planet, business, and consumers. 5 a b World Resources Institute and World Business Council for Sustainable Development.

Packaging 52

Packaging Pharmaceutical Companies Pharmaceutical Companies Compounding 52

ISPE

FEBRUARY 15, 2023

ICH has the mission “to achieve greater harmonization worldwide to ensure that safe, effective, and high-quality medicines are developed and registered in the most resource-efficient manner.” Harmonization of global regulatory requirements has been progressing for more than thirty years under the International Council for Harmonisation (ICH).

Dosage 95

Dosage FDA 95