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Nine for 2022: International issues that are compelling, new or changed in 2022

pharmaphorum

billion doses administered globally by 4th January, with 25 different vaccines either approved for use or under emergency use authorisation , 2022 starts on a more sombre note due to the rise of the Omicron variant. The next phase of the Covid-19 – from vaccines to treatments. Despite an estimated 9.25

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Oral COVID Agents

Pharmacy Friday Pearls

18 years Administration Oral Oral Oral PK/PD MOA: Nirmatrelvir – inhibitor of the SARS-CoV-2 main protease Prevents viral replicationRitonavir is a CYP3A inhibitor included to increase nirmatrelvir plasma levelsRitonavir alone has NO activity against SARS-CoV-2 Time to peak: Nirmatrelvir: 3 hrs & Ritonavir: 3.98 Introduction.

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Top 20 RNAi Therapeutic Companies Based on 2022 R&D Expenditure

PharmaShots

In 2022, the global market size of RNAi drug delivery was valued at $69.2B. Even though the company manages to generate a considerable revenue of $21.18M in 2022 through its collaborative agreements, Silence Therapeutics still waiting for the approval of its products. R&D Expenditure: $85.1M R&D Expenditure: $437.9M

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Pharma’s post-pandemic launch performance problem: what’s the prognosis?

pharmaphorum

COVID vaccines and treatments have created a substantial market over and above the existing Rx market- IQVIA estimates that the cumulative value of COVID vaccines could be between $185 and 295bn to 2026. The initial pandemic lockdowns prevented many patients from seeing doctors face-to-face.

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Agile, Data-Driven Life Cycle Management for Continuous Manufacturing

ISPE

billion US in 2022 for the global market share for prescription drugs produced using CM. 1 , 4 A Retrospective Journey In 2015, Vertex’s Orkambi was the first approved drug produced under a CM process for the treatment of cystic fibrosis. This is demonstrated by the rise from $1.05 billion US in 2021 to $1.9

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How Balancing Iron Levels Can Help Your Thyroid

The Thyroid Pharmacist

And as we’ve seen, even with supplementation, you need to address your root causes to prevent iron supply and demand challenges. 42] In a smaller 2022 study, 13 non-professional female athletes were evaluated for iron deficiency. Patients on hemodialysis may be prescribed IV or subcutaneous ESAs during dialysis treatments.

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How Do Adaptogenic Herbs Benefit Hashimoto’s?

The Thyroid Pharmacist

Nikolai Lazarev defined adaptogens as “an agent that raises the body’s ability to resist stress by countering undesired stressors, whether physical, chemical, emotional, or biological.” Would you like to know if adaptogenic herbs might be of benefit to you? This can also mean fewer nutrients are absorbed.