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Bird Flu Samples Found in Dairy Products Across the US

Drug Topics

As the H5N1 bird flu virus continues to spread across dairy cattle in the US, researchers and government health officials are ramping up testing to stop the spread.

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Pharmacy Focus - Pharmacist-Led Initiatives on C diff Rates

Pharmacy Times

On this month's episode Laura Gillespie, PharmD, discusses her paper “Impact of Pharmacist-Led Initiatives on Health Care–Associated Clostridioides difficile Rates.

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Study Finds Relationship Between Uncontrolled Severe Asthma, Exacerbations and Health Care Resource Use

Pharmacy Times

The findings emphasize a need for guideline-based care delivery for patients with severe asthma, particularly for patients who are facing social disparities within health care.

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Early tests of H5N1 prevalence in milk suggest U.S. bird flu outbreak in cows is widespread

STAT

Andrew Bowman, a veterinary epidemiologist at Ohio State University, had a hunch. He had been struck by the huge amounts of H5N1 virus he’d seen in milk from cows infected with the bird flu and thought that at least some virus was getting off of farms and going downstream — onto store shelves. He knew the Food and Drug Administration was working on its own national survey of the milk supply.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Pfizer and BioNTech commence legal action against Moderna in UK court

Pharmaceutical Technology

Pfizer and its Germany partner BioNTech have urged London’s High Court to invalidate competitor Moderna's patents over technology instrumental in the Covid-19 vaccines development as the latest phase of a global legal fight that started yesterday (23 April), reported Reuters.

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Amae Health picks up $15M to scale in-person clinics providing care for severe mental illness

Fierce Healthcare

Amae Health launched in January 2022 to improve care for individuals with severe mental illness through a community-based, integrated approach. | Amae Health, which opened its first outpatient clinic in Los Angeles 18 months ago, closed a $15 million series A round to fuel its growth as it plans to open new clinics in four markets.

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Cattle testing for H5N1 bird flu will be more limited than USDA initially announced

STAT

New federal rules aimed at limiting the spread of the H5N1 bird flu virus among dairy cattle go into effect Monday, but detailed guidance documents released Friday by the U.S. Department of Agriculture reveal its mandatory testing order is less stringent than initially described. While that is easing concerns from farmers and veterinarians about the economic and logistical burden of testing, it leaves questions about how effective the testing program will be at containing additional outbreaks.

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Novartis nominates former Bristol Myers CEO Giovanni Caforio as its new chair. Will M&A deals follow?

Fierce Pharma

Giovanni Caforio, M.D., is lining up a new gig soon after handing all his Bristol Myers Squibb leadership roles in March. | Giovanni Caforio, M.D., is lining up a new gig soon after handing all his Bristol Myers Squibb leadership roles in March. The recent Big Pharma CEO, known for steering the $74 billion acquisition of Celgene, has been proposed as the new chair at Novartis for 2025.

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Cost of developing new drugs may be far lower than industry claims, trial reveals

The Guardian - Pharmaceutical Industry

Exclusive: MSF calls for transparency after its bill for a trial of TB treatment came to a fraction of the billions claimed by pharmaceutical companies Doctors have for the first time released details of their spending on a major clinical trial, demonstrating that the true cost of developing a medicine may be far less than the billions of dollars claimed by the pharmaceutical industry.

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FDA Issues CRL for Epidermolysis Bullosa Gene Therapy

Drug Topics

Abeona Therapeutics’ pz-cel is an investigational autologous, COL7A1 gene-corrected epidermal sheet therapy for the treatment of recessive dystrophic epidermolysis bullosa.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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FDA Approves Pivmecillinam for Treatment of Female Adults With Urinary Tract Infections

Pharmacy Times

Pivmecillinam (Pivya) tablets were approved for female adults with uncomplicated urinary tract infection caused by Escherichia coli, Proteus mirabilis, and Staphylococcus saprophyticus.

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USDA orders H5N1 testing of some dairy cows to limit spread of bird flu

STAT

The U.S. Department of Agriculture moved to try to limit spread of the H5N1 bird flu virus among dairy cattle on Wednesday, issuing a federal order that will require an animal to test negative for the virus before it can be moved across state lines. It also requires laboratories and state veterinarians to report to the USDA any animals that have tested positive for H5N1 or any other influenza A virus.

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FTC votes 3-2 on final rule to ban noncompete agreements, but legal challenges expected

Fierce Healthcare

The Federal Trade Commission (FTC) voted 3-2 Tuesday to issue a final rule striking new noncompete agreements for all workers and phasing out existing noncompetes for all but senior executives acro | The final rule, which does not apply to nonprofits, forbids noncompete contracts for all new hires and winds down existing noncompetes for all employees who are not senior executives.

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Owlstone secures $6.5M for breath-based diagnostics for infectious disease

pharmaphorum

Owlstone Medical has secured a $5 million equity investment and initial $1.5 million grant funding, committed by the Bill and Melinda Gates Foundation, for development of breath-based diagnostic solutions to improve outcomes in the developing world.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Influenza Vaccines: Is the Quality of Evidence the Same?

Drug Topics

In response to historically low flu vaccine coverage rates, Kristen Thorson, PharmD, urges pharmacists to think back to their pandemic immunization efforts and “know the power of their recommendation,” to boost public protection from influenza.

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Optical Sensor Shows Promise in Non-Invasive Continuous Glucose Monitoring

Pharmacy Times

Optical glucose sensing techniques have been reported, but they require complex optical instrumentations found in laboratories, so feasibility for patient use has been challenging.

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Mental health crisis centers and EmPATH units: offering care that busy ERs can’t

STAT

On a spring afternoon in Tucson, Ariz., about a half dozen children and teens hung out in the sunny common room of Pima County’s Crisis Response Center. Beyond the pastel-painted room stretched a long, wide hall where partitions separated individual beds, many left unmade with rumpled sheets. Wearing scrubs, the kids sat in rocking chairs, watched TV, talked and laughed.

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Walgreens expands specialty pharmacy business to gene and cell therapy services

Fierce Healthcare

Walgreens is expanding its specialty pharmacy services to offer gene and cell therapy services, supported by a dedicated 18,000-square-foot center in Pittsburgh, the company announced Thursday. | Walgreens is expanding its specialty pharmacy services to offer gene and cell therapy services, supported by a dedicated 18,000-square-foot center in Pittsburgh, the company announced Thursday.

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Moderna banks on OpenAI to accelerate mRNA research 

pharmaphorum

In an ambitious move, Moderna has teamed up with OpenAI, the artificial intelligence company behind ChatGPT, to further integrate generative AI (GenAI) across its mRNA drug development and manufacturing operations.

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Scott Soefje, PharmD: Take a Site-Specific Approach to Optimize Care Delivery, Finances

Drug Topics

According to Scott Soefje, PharmD, understanding nuances across sites of care can help health care providers optimize patient care delivery while ensuring financial viability across all settings.

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FDA Grants Accelerated Approval to Tovorafenib for Pediatric Patients With BRAF-Mutated LGG

Pharmacy Times

Tovorafenib is the first systemic therapy to be approved for the treatment of pediatric patients who have low-grade glioma with BRAF rearrangements or fusions.

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H5N1 bird flu virus particles found in pasteurized milk but FDA says commercial milk supply appears safe

STAT

WASHINGTON — Testing conducted by the Food and Drug Administration on pasteurized commercially purchased milk has found genetic evidence of the H5N1 bird flu virus, the agency confirmed Tuesday. But the testing, done by polymerase chain reaction, or PCR, cannot distinguish between live virus or fragments of viruses that could have been killed by the pasteurization process.

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FDA Approves Pfizer’s Gene Therapy for Adults with Hemophilia B

BioPharm

Beqvez (fidanacogene elaparvovec-dzkt), a one-time gene therapy, helps adults with hemophilia B produce factor IX themselves instead of receiving regular intravenous infusions.

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Simple HealthKit partners with Amazon to increase access to at-home diagnostics and chronic care

Fierce Healthcare

Simple HealthKit is bringing chronic condition diagnostics to front porches across the country via a new partnership with Amazon. | Consumers can now buy Simple HealthKit’s at-home tests for diabetes (HbA1c), respiratory wellness and sexual wellness and have it shipped to their door through Amazon.

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Recreational Marijuana Laws Did Not Increase Substance Use Among Adolescents

Drug Topics

With more states allowing the use of recreational marijuana than ever before, researchers examined its effects among youth populations.

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FDA Approves Ankiva Plus Bacillus Calmette-Guérin For Non-Muscle Invasive Bladder Cancer

Pharmacy Times

The approval was based on the QUILT-3.032 study, which included 77 adults with carcinoma in situ with or without papillary tumors after a transurethral resection.

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Massive amounts of H5N1 vaccine would be needed if there’s a bird flu pandemic. Can we make enough?

STAT

The unsettling reality of H5N1 bird flu circulating in dairy cow herds in multiple parts of the United States is raising anxiety levels about whether this dangerous virus, which has haunted the sleep of people who worry about influenza pandemics for more than 20 years, could be on a path to acquiring the ability to easily infect people. To be clear, there is no evidence that this is currently the case — the sole confirmed human case reported in Texas three weeks ago was in a farm worker w

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FDA initiative puts AR/VR at heart of home health drive

pharmaphorum

A new FDA initiative is seeing how augmented reality and virtual reality (AR/VR) can make patients’ own homes an integral part of the healthcare system

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CMS sets Medicaid payments to home care workers at 80%

Fierce Healthcare

The Centers for Medicare & Medicaid Services is hoping to improve Medicaid enrollees’ access to care through a final rule that better compensates caregiving roles. | CMS released a series of final rules Monday, including Medicaid access regulations that some groups worry will cause providers to close.

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The Stages of Shingles

Drug Topics

The clinical manifestations of shingles can be divided into 3 phases.

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Considerations When Treating Migraines in Gender Diverse Patients Receiving Gender-Affirming Hormone Therapy

Pharmacy Times

The AAN speaker highlights what health care providers need to know when treating migraines in populations on hormone therapy, as well as how hormones can influence migraines.

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Decline in heart failure deaths has been undone, led by people under 45

STAT

Heart failure mortality rates are moving in the wrong direction, a new analysis reports, reversing a decline in deaths that means more people in the United States are dying of the condition today than 25 years ago. The concerning conclusion comes as newer medications are raising hopes for better outcomes in the years to come. A research letter published Wednesday in JAMA Cardiology tracked U.S. death certificate data from 1999 through 2021, revealing a steady drop in deaths until 2012, when rate

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Can a sinus infection cause a fever?

The Checkup by Singlecare

Sinus infections , also known as sinusitis, occur when a virus or bacteria causes inflammation and mucus buildup in your nasal passages. The swelling of the tissue lining your sinuses causes stuffy nose, facial pain, sneezing, runny nose, nasal congestion, sore throat, postnasal drip, and other symptoms that can feel similar to a common cold. They vary in length of illness and severity.

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Evernorth's Accredo to offer Humira biosimilar at $0 out-of-pocket

Fierce Healthcare

Evernorth's Accredo arm will make a Humira biosimilar available to patients with no out-of-pocket costs, the company announced Thursday. | Evernorth's Accredo arm will make a Humira biosimilar available to patients with no out-of-pocket costs, the company announced on Thursday.

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