Sat.Jan 09, 2021 - Fri.Jan 15, 2021

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J&J single-shot COVID-19 vaccine shows early promise

pharmaphorum

J&J has announced early trial results that suggest its single-shot coronavirus vaccine provides a sustained response against the virus ahead of a phase 3 trial readout due later this month. The UK has caused controversy in recent weeks by tinkering with the dosing regimens for coronavirus vaccines from AstraZeneca and Pfizer/BioNTech, which are being rolled as part of the country’s mass vaccination programme.

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Neurology’s Growing Need for Disposable Technologies

Pharma Mirror

By Boris Goldstein, Co-Founder & Executive Chairman at Brain Scientific COVID-19 is known for its impacts on a patient’s respiratory system, but it has also been found to affect individuals in unique ways and with varying severity levels depending on their age, risk factors, and comorbidities. Several studies have recently shown that the development of neurological conditions and symptoms are prevalent in COVID patients.

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What is the best over the counter migraine medication?

Druggist

Migraine is a common condition affecting an estimated 6 million people in the UK. With approximate 190,000 migraine attacks experienced by people in the UK (NICE, 2012), pharmacies are among the first points of call to find over the counter migraine medication. What is the best painkiller for migraine? Today I will review common over the counter migraine medication.

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Fight against pharma counterfeiting must go deeper: TruTag

Outsourcing Pharma

A leader from the anti-counterfeit solutions firm says that while packaging-level efforts may have an effect, on-dose technology is worth a closer look.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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GSK’s Neale Belson on building trust with employees and society

pharmaphorum

Pharma’s reputation is currently riding high as the industry comes together to tackle COVID-19, but GSK’s UK general manager Neale Belson says there is always more companies can do to build their culture and make sure employees and customers trust they are doing the right thing. When we spoke with Belson about the GSK’s response to COVID-19 , he pointed out how the pandemic has allowed him to get to know his colleagues even better than he anticipated.

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Things to Consider When You are Making Your Own Scrubs

Pharma Mirror

Whenever you see physicians, nurses, or any hospital worker, there’s a good chance that they’re wearing scrubs. This sanitary clothing or uniform was originally designed for use by surgeons and their support staff while in surgery rooms. It came to be known as scrubs because surgeons typically put them on as they sterilize or scrub themselves clean before entering the operating room.

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Global alliance unites pharma pros to battle counterfeiting

Outsourcing Pharma

Fight the Fakes gathers manufacturers and other stakeholders to brainstorm on ways to combat falsified medicines and safeguard the worldâs medicine supply.

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NICE recommends interim funding for GSK’s Zejula in ovarian cancer

pharmaphorum

Women with newly-diagnosed advanced ovarian cancer have a new treatment option in England after NICE recommend interim funding for GlaxoSmithKline’s Zejula (niraparib) in final guidance. Zejula competes with AstraZeneca/Merck & Co’s PARP inhibitor class rival Lynparza (olaparib) but in this case it has an advantage in this maintenance therapy use as it can be used regardless of whether the BRCA mutation is present.

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Health professions ask public to take concrete actions to help safeguard underfunded COVID-affected health systems

Pharma Mirror

Geneva – The presidents of all five international organisations that make up the World Health Professions Alliance (WHPA) have called for continued support for health and care workers in 2021 in a joint video message released today. International Council of Nurses president Ms Annette Kennedy, said: “As health professionals, most of us have been fighting the COVID-19 pandemic.

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10 Questions Ambulatory Surgery Centers Should Ask a Potential Pharmacy Partner

indispensable health

Ask the Right Questions of Potential Pharmacy Service Partners For Your ASC. The First Step is to Ensure a Potential Pharmacy Service Partner is Capable of Benefiting the ASC. Regardless if an Ambulatory Surgery Center (ASC) is in pre-construction or has been operating for years, it is essential to ask questions of any prospective pharmacy service partner.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Lexaria broadens COVID-19 drug exploration program

Outsourcing Pharma

The drug delivery platform company is exploring the viability of remdesivir and other potential treatments for the virus using its DehydraTECH technology.

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Celltrion closes in on COVID-19 antibody market after trial success

pharmaphorum

South Korea’s Celltrion has announced encouraging top-line results for its potential antibody therapy for COVID-19, with the first part of a phase 2/3 trial showing it could cut recovery times and chances of progression from moderate to more severe disease. Several other companies are also working on antibody therapies and Eli Lilly’s bamlanivimab gained an FDA Emergency Use Authorization in November last year, shortly after Regeneron’s cocktail of casirivimab and imdevimab.

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Pleio and Medisafe Showcase Human-to-Digital Patient Engagement Future

Pharma Mirror

New program combines human hello to digital embrace for long-term medication support Boston, MA – Medisafe, a leading digital drug companion company, is teaming up with Pleio to launch a new integrated digital health model with a unique combination of human and digital resources. Known as the GoodStart program, Pleio’s concierge service uses mentors to acclimate patients on their prescription therapy via live phone calls and digital nudges, meeting patients’ need for human connection.

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PharmD-2021 | September 20-22 | Washington D.C.

Pharma Marketing Network

Scientia Meetings cordially invites all the participants from all over the world to attend “International Conference on Pharmaceutical Research and Drug Development” which will be held during September 20-22, 2021 in Washington D.C. PharmD-2021 provides many exciting opportunities for scientists to create a unique program to hear presentations most suited to one’s personal interests by going back and forth among concurrent conferences.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Counterfeit Janssen HIV drug discovered in US pharmacies

Outsourcing Pharma

The pharmaceutical firm reports a counterfeit version of its Symtuza HIV treatment has been found and pulled from shelves at three American pharmacies.

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Are face-to-face medical meetings a thing of the past?

pharmaphorum

Everything, from exercise classes to pub quizzes, went online last year – and medical education was no exception. In their droves, congresses, conferences, and masterclasses went virtual in a bid to ensure healthcare professionals were supported, up to date, and socially distanced. But is this change here to stay? Are the days of queuing for coffee, rushing to symposiums, and the glitzy conference dinner a thing of the past?

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Unearthed Trauma and Double Standards Regarding the DC Insurrection

Colors Make me Happy

Smoke covering Baghdad, Iraq on April 2nd, 2003. This past Wednesday (January 6 th ) was a day that many Americans will never forget. It was one of those defining moments in time, where years later you recall where you were and how you felt as you watched the events unfolding. However, in my case those events unearthed a range of buried emotions and past trauma, the sort of thoughts one must let out, as they eat away at you if you imprison them within your head.

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Pain Management & Opioid CME Requirements by State

Board Vitals - Pharmacist

Each state’s medical licensing board has its own set of requirements for medical professionals to maintain their state medical licenses; some states require allotted CME hours on specific topics. As new regulations are implemented to combat the ongoing opioid crisis, more state medical licensing boards are requiring pain management and safe opioid prescribing-related CME as part of their annual continuing education requirements.

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Florida doctor pleads guilty to clinical trial data fraud

Outsourcing Pharma

A Miami physician has owned up to falsifying research data and patient participation figures for a pediatric asthma trial conducted from 2013 to 2016.

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IO Biotech raises $155m to develop breakthrough cancer vaccine

pharmaphorum

IO Biotech, an oncology specialist formed and backed by Denmark’s Novo Holdings, has raised €127 million ($155 million) to further develop its cancer vaccine technology that has boosted efficacy of PD-1 immunotherapy in early trials. The Series B fundraiser follows the FDA’s decision to grant Breakthrough Therapy designation last month for a combination of its lead immune-oncology therapies IO102 and IO103, with anti-PD-1 monoclonal antibodies for patients with metastatic melanoma.

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Senna and Loperamide Scheduled

Med Ed 101

Somedays I scratch my head more than others…today was one of those days. Seeing Senna and loperamide scheduled together made me scratch it REAL hard. A 77-year-old male was complaining of constipation and Miralax PRN was added to help. As I started reviewing the medication list, I realized that this patient was on both Senna […]. The post Senna and Loperamide Scheduled appeared first on Med Ed 101.

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Boehringer Ingelheim announces partnership with Google

Pharma Times

Partnership will aim to research and implement quantum computing in pharma R&D

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AI-driven drug discovery collaboration to tackle neurological diseases

Outsourcing Pharma

Sosei Heptares and PharmEnable will harness artificial intelligence-enabled technology and advanced chemistry to explore neurological disease solutions.

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RNAi biotech Atalanta debuts with $110m plus Biogen and Roche CNS tie-ups

pharmaphorum

US biotech Atalanta Therapeutics has come out of stealth mode backed with $110m from Biogen and Roche, who have also signed separate partnerships to develop new therapies for neurological diseases using RNA interference (RNAi) technology. While there are RNAi products on the marketplace, with Alnylam becoming the first company to get a product approved in 2018, it is difficult to get this class of drug distributed through the brain and spinal cord.

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5 OTCs That Cause GI Issues

Med Ed 101

Over-the-counter medications play a huge role in modern healthcare. In my practice, I’ve had caught many adverse effects simply by reviewing the entire medication list and asking about OTCs. Here are my top 5 OTCs that cause GI issues. NSAIDs NSAIDs are arguably one of the most common OTC medications that patients will try for […]. The post 5 OTCs That Cause GI Issues appeared first on Med Ed 101.

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NHS England selects supermarket Asda to operate COVID-19 vaccination centre

Pharma Times

Qualified pharmacists will administer the Pfizer/BioNTech vaccine at an in-store pharmacy

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LA customs agents seize $19m in counterfeit Viagra pills

Outsourcing Pharma

Authorities discovered the fake Pfizer erectile-dysfunction tablets in one of three cargo containers full of fraudulent goods, recently arrived from China.

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2021 – The healthcare changes here to stay

pharmaphorum

2020 was the year that changed everything, and as the new year begins many are wondering what awaits the world in 2021. Impetus Digital co-founder and CEO Natalie Yeadon reflects on the last 12 months and shares her views on the healthcare, research and digital changes that could be here to stay. I think it is fair to say that 2020 will not be particularly missed by anyone.

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Could Lilly’s donanemab readout in Alzheimer’s boost Biogen’s prospects?

pharmaphorum

When Eli Lilly reported results for donanemab in Alzheimer’s disease earlier this week it was hailed as a rare win for the amyloid hypothesis, although there’s no shortage of candidates that have failed despite positive mid-stage trial results. Some analysts have intimated that given the small size of the study at just over 270 patients, rival amyloid drug developers Biogen and Eisai could claim the biggest benefit from the data in positive sentiment ahead of an FDA decision later this year.

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Boehringer, Lilly’s Jardiance ties to match AZ’s Farxiga with heart failure label

pharmaphorum

Boehringer and Eli Lilly have moved closer to a heart failure indication for their SGLT2 inhibitor Jardiance, as the FDA starts a fast-track review of the drug in its first use beyond diabetes. The US regulator is looking at data from the EMPEROR-Reduced trial of Jardiance (empagliflozin), which found that the drug achieved a 25% reduction in the combined primary endpoint of cardiovascular death or hospitalisation compared to placebo.

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Sanofi buys UK’s Kymab and inflammatory disease hopeful for $1.45bn

pharmaphorum

Sanofi is to acquire UK biotech Kymab in a deal worth up to $1.45 billion as the big French pharma seeks to add to its pipeline of drugs that treat inflammatory diseases and cancer. Cambridge-based Kymab is one of several rising stars on the UK biotech scene, with technology that uses transgenic mice to develop antibodies optimised for the human immune system.

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Enabling new models of care: pursuing pharma’s partnership potential

pharmaphorum

There is a huge, ongoing shift in how health and wellness is approached in the UK, and the changes will have important implications for NHS-industry partnerships. Transformative change is coming to the NHS and is set to radically alter how the UK’s health service cares for people at a population level. The NHS Long Term Plan signposted this change, with its emphasis on preventative health, and the forthcoming expansion of the Integrated Care Systems programme continues this direction of travel o

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Hackers posted stolen COVID-19 vaccine info online, says EU regulator

pharmaphorum

Hackers posted stolen confidential information about Pfizer/BioNTech’s COVID-19 vaccine online, the European Medicines Agency has said in an update. The EMA last month revealed that documents relating to the Pfizer/BioNTech vaccine were stolen in a cyber-attack on its records. Since then the agency has been investigating the incident involving the theft of documents that formed part of BioNTech’s filing for the BNT-162b vaccine.

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Study says COVID-19 infection provides immunity, but people can transmit virus

pharmaphorum

Previous COVID-19 infection provides some immunity for at least five months, but people may still carry and transmit the virus, according to a study by Public Health England. A first report from PHE’s SIREN study found antibodies from previous COVID-19 infection provide 83% protection against reinfection for at least five months. It found that reinfections in people with antibodies were rare, with only 44 potential reinfections among 6,614 participants who showed evidence of previous infection.