Sat.Jan 14, 2023 - Fri.Jan 20, 2023

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WTAS: Inflation Reduction Act already impacting R&D decisions

PhRMA

The Inflation Reduction Act’s (IRA’s) drug price setting provisions, as predicted, are already impacting biopharmaceutical research & development (R&D) decisions. Whether you are looking at estimates of how many fewer medicines or indications will be developed, or noting shifts away from areas of unmet patient need because the law is signaling those innovations are not valued, the IRA’s price setting provisions are a loss for patients everywhere.

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Three-Dose Hepatitis B Vaccine Regimen Can Protect Those With HIV

Drug Topics

Previously hepatitis B vaccines have offered lower levels of protection for people living with HIV. New research indicates that a 3-dose series could offer much better protection.

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Study: Empagliflozin Can Slow Progression of Chronic Kidney Disease to Kidney Failure

Pharmacy Times

Data from a randomized clinical trial supports previous clinical findings on SGLT2 inhibitors and their ability to slow the progression of chronic kidney disease.

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HIV vaccine being developed by Johnson & Johnson fails clinical trial

STAT

Yet another experimental HIV vaccine has failed. The National Institute of Allergy and Infectious Diseases reported Wednesday that a Phase 3 clinical trial of a vaccine was stopped because the vaccine was ineffective at preventing HIV infection. The vaccine was being developed by Janssen, the vaccine division of Johnson & Johnson.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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ICYMI: PhRMA kicks off the year at the 2023 J.P. Morgan Health Care Conference

PhRMA

This January, PhRMA joined health care leaders, investors, R&D experts and members of the media at the 2023 J.P. Morgan Health Care Conference in San Francisco, CA. During this week, we discussed ways to improve patient outcomes, access and affordability in our health care system.

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Antipsychotic Prescriptions on the Rise Among Pediatric Patients

Drug Topics

A recent study found a rise in the prevalence of antipsychotic prescriptions among pediatric patients and noted which antipsychotics were most commonly used for specific indications.

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Mix-it-yourself Wegovy? Some are trying risky sources for weight-loss drugs

STAT

With a few clicks, Daniel added the chemical to his online cart and ordered it. In less than a week, a vial containing white powder arrived at his house. He used a syringe to measure out sterile water and eject it into the vial to dissolve the powder. Then, with a different syringe, he drew up about a quarter of a milliliter of the solution and injected it into his lower abdomen.

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How to meditate for anxiety and depression

The Checkup by Singlecare

When most people hear the word meditation, they probably imagine someone sitting perfectly still in a quiet room, legs crossed, zoned out in a state of total bliss. But meditation can be performed in many different ways, and while it does take some practice to get the hang of it, even just a few minutes a day can help reduce some symptoms of common mental health conditions like anxiety and depression.

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SmartRx Joins Other Prescription Drug Discount Programs

Drug Topics

A new membership program, SmartRx, offers consumers savings on prescriptions, as well as office visits, eye care, vaccines and pet meds.

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AI Could Improve Blood Sugar Management in Type 1 Diabetes

Pharmacy Times

An app using AI to evaluate blood sugar data, concerning trends, and recommend management tools will be a part of a clinical trial in 2024 for further assessment.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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A new study links social media use to changes in teen brains. Is that a bad thing?

STAT

Today’s teens and tweens have never known a world without social media. There are still a lot of open questions about how sites like TikTok and Instagram may shape their development — and stories focusing on the potential negative impacts of social media tend to dominate the news. But a recent study published in JAMA Pediatrics is the latest in a growing body of research that suggests the relationship that young people have with social media is too complicated to be categorized as

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AI continues to gain momentum in the biopharmaceutical industry in 2023

Pharmaceutical Technology

While the biopharmaceutical industry has been impacted and pressured by various factors such as the Covid-19 pandemic, inflation, the Ukraine-Russia war, ongoing supply chain issues, and a challenging economic environment, collaboration between pharma companies and emerging technologies providers continues to grow, especially in the research and development (R&D) field, offering some resilience in times of geopolitical and economic disruptions.

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Tdap Vaccine Approved by FDA for Use During Pregnancy for Pertussis Prevention

Drug Topics

The FDA has approved another Tdap vaccine option for use during pregnancy to prevent pertussis, otherwise known as whooping cough.

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Artificial Intelligence Tool Reflects Risk of Cognitive Decline, Alzheimer Disease Based on Brain Age

Pharmacy Times

The model can predict the chronological ages of cognitively normal participants with an average absolute error of 2.3 years, which is about 1 year more accurate than an existing model.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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The addiction crisis is causing a spike in endocarditis cases. Hospitals are struggling to respond

STAT

Increased injection drug use has led to a spike in cases of the life-threatening heart condition endocarditis , with cases rapidly accelerating since the onset of Covid-19. The increased case count is one of the lesser-known side effects of the deadly addiction epidemic. But patients with endocarditis, an inflammation of the heart lining caused by infection, require complex, thoughtful care — care that the U.S. health system is ill-equipped to provide.

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New Jefferson Health program enables clinical, academic nurses to partner on research

Fierce Healthcare

New Jefferson Health program enables clinical, academic nurses to partner on research agliadkovskaya Wed, 01/18/2023 - 14:16

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Rising Prices for Insulin Cause for California's Lawsuit Against Drug Makers, PBMs

Drug Topics

Pharmaceutical makers, price managers out of control with ‘necessary drug’ for millions, Attorney General says.

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Hospitalizations for Mental Health Conditions Increased During the Pandemic Among Adolescents

Pharmacy Times

Study notes that evaluating changes in the proportion of hospitalizations for mental health conditions among adolescents is vital to ensure the prioritization of public health programs that address psychiatric health care needs that emerged during the COVID-19 pandemic.

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STAT+: Moderna says RSV vaccine worked, setting stage for competition with GSK and Pfizer

STAT

Moderna’s vaccine against the respiratory syncytial virus, or RSV, reduced the rate of lower respiratory disease in people over 60 in a Phase 3 trial, the company said Tuesday. The result will increase competition in a soon-to-be crowded market. The drug giants Pfizer and GlaxoSmithKline have already presented results for their RSV vaccines in older individuals, and have been preparing for what could be a brisk marketing battle.

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Black patients get better care when nurse practitioners have full practice authority: study

Fierce Healthcare

Black patients get better care when nurse practitioners have full practice authority: study. fdiamond. Wed, 01/18/2023 - 15:46.

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Urgent Need to Increase Vaccinations in Children

Drug Topics

Childhood vaccinations took a downturn during the pandemic. Now is the time to get them done and pharmacists can help.

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Pharmacy Focus - Big Picture for Health-System Pharmacies

Pharmacy Times

Carina Dolan, PharmD, BCOP, senior director for Clinical Oncology and Pharmaceutical Outcomes at Vizient Inc, discusses the highlights and big picture moving forward for hospitals and health-system pharmacies.

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In the search for therapies for solid tumors, companies are turning to a novel target: claudin-6

STAT

On Target is a recurring feature from STAT that dives deep into the most promising drug targets in oncology. This column is adapted from the new STAT Report : Targeting cancer: the new frontier of immunotherapy and precision oncology. Targeted immunotherapies like CAR-T have been remarkably successful in combating blood cancers like chronic lymphocytic leukemia.

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Let’s Get Social: The Ascendancy of Social Media to the Top of the Media Mix

PharmExec

Fran Pollaro talks with Amanda Powers-Han, chief marketing officer at Greater Than One, a full-experience marketing agency dedicated to healthcare, about what’s trending in early 2023 for pharma media mixes.

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Recommended Immunization Schedules for 2023

Drug Topics

The updates include new recommendations for COVID-19 and pneumococcal vaccines.

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BONUS: Public Health Matters - Highlighting Women of Color in Pharmacy

Pharmacy Times

This week's episode features Amina Abubakar, PharmD, AAHIVP, CEO of Avant Pharmacy & Wellness Center and president of Avant Institute, who discusses her experience in the pharmacy industry and the communities she serves.

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US eyes link between Pfizer bivalent COVID jab and stroke

pharmaphorum

Regulatory authorities in the US are investigating a possible link between the new Pfizer/BioNTech bivalent COVID-19 booster vaccine and strokes in people aged 65 or over, but still recommend the shots. Monitoring has pointed to a possible higher risk of ischaemic stroke in the 21-day period post-vaccination in this age group compared to 22 to 44 days post-vaccination, according to an announcement on the Centre for Disease Control and Prevention (CDC) website. “Although the totality of the

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CDC probes possible safety risk for Pfizer's new COVID shot, sees no need to change vaccine practices

Fierce Pharma

CDC probes possible safety risk for Pfizer's new COVID shot, sees no need to change vaccine practices. zbecker. Tue, 01/17/2023 - 11:49.

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Extended-Release Risperidone Approved by FDA for Schizophrenia

Drug Topics

Rykindo is a bi-weekly long-acting risperidone injection to treat patients with schizophrenia and bipolar 1 in adults.

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Study: Most Long COVID-19 Symptoms Resolve Within a Year After Mild Infection

Pharmacy Times

COVID-19 infection was significantly associated with increased risks of several conditions, including loss of smell and taste, concentration, and memory impairment.

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Dollar General pilots mobile clinics as it targets a bigger presence in healthcare

Fierce Healthcare

Dollar General pilots mobile clinics as it targets a bigger presence in healthcare hlandi Fri, 01/20/2023 - 18:25

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U.S. plans crackdown on nursing homes that sedate patients with unnecessary antipsychotics

STAT

WASHINGTON (AP) — The federal government says it will begin a targeted crackdown on nursing homes’ abuse of antipsychotic drugs and misdiagnoses of schizophrenia in patients. The Centers for Medicare and Medicaid Services is launching investigations this month into select nursing homes, aimed at verifying whether patients have been properly diagnosed with the psychiatric disorder.

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FDA Grants Priority Review Designation to OPNT003 Nasal Nalmefene for Opioid Overdose

Drug Topics

The PDUFA date has been set for May 22, 2023.

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FDA Approved IND for CAR T Cell That Target Metastases-Causing Breast Cancer Tumor

Pharmacy Times

The head of the CAR T cell antibody can recognize and target the growth factor in its tumor microenvironment.

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