Drug Topics

MAY 15, 2023

Marketing costs money, so be sure to spend wisely.

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Independent Pharmacies 187

Drug Topics

MAY 16, 2023

The National Community Pharmacists Association now has plenty of allies in its fight with the pharmacy benefit managers.

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Pharmacy Times

MAY 17, 2023

Good practice for older adults is that calories should go down while nutrient intake goes up as they age.

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STAT

MAY 19, 2023

A defanged form of CRISPR, which doesn’t slice or nick DNA, but rather alters the epigenome — the layers of chemical coding that sit on top of DNA and control the activity of genes — has aced its first substantive test. When researchers used CRISPR “ epigenome editing ” to dial down a cholesterol-associated gene in monkeys, the animals’ blood levels of heart-disease-causing LDL, or “bad” cholesterol, plummeted by more than 50%, Jennifer Kwo

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Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

FDA

Pharmaceutical Technology

MAY 19, 2023

The US Food and Drug Administration (FDA) has granted approval to Bausch + Lomb and Novaliq’s Miebo (perfluorohexyloctane ophthalmic solution) to treat the signs and symptoms of dry eye disease (DED). Formerly known as NOV03, Miebo is a first-in-class eye drop designed for preventing the evaporation of excessive tears and restoring tear balance in evaporative DED patients.

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Drug Topics

MAY 19, 2023

Seasonal influenza kills hundreds of thousands of people every year due to a constantly changing virus and highly inefficient vaccine production. A universal flu vaccine could deal with the first problem, and mRNA technology with the second.

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Vaccines 198

STAT

MAY 17, 2023

WASHINGTON — More than a quarter of American adults are depressed, a 10% surge from nearly a decade ago, according to the latest Gallup survey. The data come as the Biden administration tries to overhaul mental health care costs and boost the number of health care workers licensed to practice behavioral health care. Congress in this year’s budget also allotted hundreds of millions of dollars to mental health care grants and programs, many of them trained on children or substance mi

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Fierce Pharma

MAY 19, 2023

Krystal's Vyjuvek becomes first topical gene therapy with FDA nod to treat rare skin disease zbecker Fri, 05/19/2023 - 16:25

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FDA 145

Drug Topics

MAY 15, 2023

Balanced products showed greater improvements compared to either CBD-dominant or THC-dominant products.

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Pharmacy Times

MAY 15, 2023

Investigators of the phase 2 study also found a comparable reactogenicity to the individual influenza and COVID-19 vaccines from Novavax or authorized vaccine comparators.

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Vaccines 139

STAT

MAY 17, 2023

When someone has leprosy, people who live in the same household face the highest odds of contracting the infection. But in a new trial, providing those contacts with a single dose of an antibiotic typically used to treat tuberculosis drastically reduced that risk, researchers reported Wednesday. The trial, which took place in China, corroborates the idea of giving close contacts an antibiotic as a way to reduce the likelihood that the disease spreads, experts said.

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Fierce Healthcare

MAY 16, 2023

Kaiser Permanente discloses timeline, financial commitments for its VBC megadeal with Geisinger Health dmuoio Tue, 05/16/2023 - 12:40

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Drug Topics

MAY 15, 2023

Doing small spurts of exercise throughout the day provide numerous benefits.

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Pharmacy Times

MAY 17, 2023

Pegfilgrastim-pbbk is a leukocyte growth factor developed to reduce the onset of infection in patients with non-myeloid malignancies administered myelosuppressive anticancer medications associated with a clinically significant rate of febrile neutropenia.

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STAT

MAY 15, 2023

When gastroenterologists learned in March that UnitedHealthcare plans to barricade many colonoscopies behind a controversial and complicated process known as prior authorization, their emotions cycled rapidly between fear, shock, and outrage. The change, which the health insurer will implement on June 1, means that any United member seeking surveillance and diagnostic colonoscopies to detect cancer will first need approval from United — or else have to pay out of pocket.

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Insurance 145

Fierce Healthcare

MAY 19, 2023

Cybersecurity attack against Amazon-owned online pharmacy PillPack exposed user health data aburky Fri, 05/19/2023 - 16:16

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Drug Topics

MAY 19, 2023

Your weekly roundup of the latest news from Drug Topics®.

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Pharmacy Times

MAY 19, 2023

Joseph Reilly, BS, PharmD, BCGP, and Andrew Skinner, MD, discuss the potential benefits of using live-jslm early on to treat CDI, as well as the implications of this new treatment.

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STAT

MAY 19, 2023

When cyclist Alison Tetrick joined the sport’s professional ranks, she received the perks that come with the job — new bikes and clothing included. But she could never get comfortable on the bike saddles. After several years, Tetrick suffered so much damage to her genital area that she eventually resorted to surgery to trim excess skin from her labia.

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Fierce Pharma

MAY 19, 2023

Intercept's NASH dreams may be dashed after FDA panel votes against Ocaliva's approval bid fkansteiner Fri, 05/19/2023 - 17:30

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FDA 133

Fierce Healthcare

MAY 19, 2023

Commercial payers frequently delayed paying out providers' claims in Q1, report finds dmuoio Fri, 05/19/2023 - 15:44

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Pharmacy Times

MAY 18, 2023

At least 150 minutes per week of moderate intensity aerobic activity, or 75 minutes of vigorous intensity aerobic activity found to improve outcomes in patients with flu or pneumonia.

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STAT

MAY 19, 2023

Four different companies agreed to buy the assets of Pear Therapeutics at auction on Thursday morning after the digital health company filed for bankruptcy last month. Click Therapeutics, Welt Corp, Harvest Bio, and Nox Health Group each acquired bits of the company for $6.05 million, far short of the $32 million in debt Pear carried. A hearing to approve the sale will be held on May 22.

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FDA 145

Pharmaceutical Technology

MAY 19, 2023

The US Food and Drug Administration (FDA) has approved AbbVie’s Rinvoq (upadacitinib) for patients with Crohn’s disease who do not respond to TNF blockers, a common immune suppressant treatment for the condition. Whilst there is a range of FDA-approved biologics for Crohn’s disease, Rinvoq is the first approved oral product for the moderate to severe type of the disease.

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Mayo Clinic Dosage FDA Immunization 105

Drug Store News

MAY 18, 2023

In a statement, Walgreens said it "disputes liability" and did not admit fault, but settling allows it to focus on patients, customers and communities.

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Pharmacy Times

MAY 18, 2023

Study finds that a more accurate estimate of the burden of RSV disease will facilitate appropriate decision making regarding the use of preventive interventions, such as vaccination.

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Vaccines 123

STAT

MAY 16, 2023

WASHINGTON — The White House is summoning naloxone manufacturers for a roundtable focused on the medication’s price, the Biden administration’s top drug policy official told STAT. The move would represent the White House’s most concrete action to date to address the price of naloxone , a medication used to reverse opioid overdoses.

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Outsourcing Pharma

MAY 18, 2023

A small molecule drug has been recommended by Englandâs National Institute for Health Care and Excellence (NICE) for the treatment of adults with moderate to severe chronic kidney disease (CKD)-associated pruritus in adult patients on haemodialysis.

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Fierce Pharma

MAY 19, 2023

AbbVie, Genmab's lymphoma drug Epkinly snags FDA approval in heated blood cancer race aliu Fri, 05/19/2023 - 11:21

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FDA 127

Pharmacy Times

MAY 16, 2023

Since the 2018 guideline’s publication, additional non-statin therapies such as bempedoic acid, evinacumab, and inclisiran, have been approved by the FDA for the management of hypercholesterolemia.

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FDA 123

STAT

MAY 19, 2023

Amid increased concerns over a lack of transparency in clinical trials, a new study found that one in five primary endpoints were changed after a late-stage study had begun, and 70% of the trials examined did not include information about primary endpoint changes in articles published in medical journals. Specifically, 145 of 755 randomized controlled trials for cancer medications — or 19% — had changes to the primary endpoints when using at least one of three different methods to

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Pharmaceutical Technology

MAY 16, 2023

CHARM Therapeutics has received investment from NVIDIA’s venture investment arm, NVentures, for deep learning-enabled drug discovery research. Representing a major milestone for the company, the investment will enable CHARM to do further work on the research and development of new medicines for oncology. It will also allow the company to continue to fund its growing organisation while utilising the accelerated computing platform of NVIDIA.

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Compounding Communication 103

Fierce Healthcare

MAY 16, 2023

UnitedHealthcare defends controversial prior authorization policy for colonoscopies fdiamond Tue, 05/16/2023 - 16:43

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Pharmacy Times

MAY 19, 2023

Amid various obstacles, health care providers and pharmacists can initiate measures to enhance compensation for pharmacy services in managed care.

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STAT

MAY 19, 2023

Twenty-five years ago, 75-year-old Bob Dole — former Republican presidential candidate and U.S. senator from Kansas — went on “ Larry King Live ” and declared himself to be sexually impotent. Later that year, he became an official pitchman for Viagra, which the Food and Drug Administration approved in late March 1998 for the treatment of erectile dysfunction — though that now-common phrase hadn’t yet made its way to the lexicon.

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European Pharmaceutical Review

MAY 19, 2023

A Phase III trial has found that the novel combination antibiotic sulbactam-durlobactam prevents at least as many fatalities of hospital-acquired pneumonia as colistin, the best currently approved treatment. This finding alongside the other data from the trial led the US Food and Drug Administration (FDA)’s Antimicrobial Drugs Advisory Committee to recommend the FDA approve the combination antibiotic for often-fatal pneumonia strain carbapenem-resistant Acinetobacter baumannii–calcoaceticus co

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