Sat.Feb 06, 2021 - Fri.Feb 12, 2021

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Triple Negative Breast Cancer Drug Development Digital Summit

pharmaphorum

Improving the Safety, Efficacy & Predictability of Monotherapy & Combinatorial Therapies to Fast-track the Discovery & Development of TNBC Treatments to Reach Patients in Need. This is the primary industry platform specifically dedicated to providing you insight into the latest developments of safe and efficacious blockbuster therapies to treat triple negative breast cancer.

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Latest FDA COVID-19 updates and activity

Outsourcing Pharma

The federal agency continues to keep researchers, pharma firms and citizens apprised of current happenings and research related to the virus and pandemic.

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MOVIANTO -DENNIS SPAMER, new Board Member of Movianto GERMANY

Pharma Mirror

The Walden Group is pleased to announce the appointment of Dennis Spamer (38) as member of the Board authorized to sign as statutory director of the company. Together with Thomas Creuzberger, who has been managing Movianto Germany since more than 20 years and Stéphane Baudry, founder and CEO of the Walden Group, Spamer shall push on the further development of the logistics specialist.

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Statins PROS and CONS [TOP LIST]

Druggist

Statins, also known as lipid-lowering drugs, are a popular class of drugs prescribed in the UK. When looking at the most popular drugs in the UK , atorvastatin was the most prescribed drug. Simvastatin also made to the top of most commonly prescribed drugs. Historically, statins have been subject to scrutiny from the press, mostly picking on a negative aspect of stain treatment.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Early data back J&J and AC Immune’s Alzheimer’s jab

pharmaphorum

Shares in Swiss biotech AC Immune have risen sharply after it said a vaccine in development for Alzheimer’s disease (AD) hit the mark in a phase 1/2 trial. . ACI-35.030, partnered with Johnson & Johnson, is designed to stimulate the body to generate antibodies against tau protein, one of the factors though to play a role in the development of AD dementia.

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People on the Move: February 2021

Outsourcing Pharma

This monthâs announcements about industry hires, promotions, alliances and other important events includes Merck, Lonza, Medable and other key firms.

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AI in Healthcare Virtual Summit | March 25-25, 2021 | Online

Pharma Marketing Network

Discover the AI methods & tools set to revolutionize healthcare, medicine & diagnostics, as well as industry applications and key insights at our AI in Healthcare Virtual Summit. This is a 2 in 1 online summit about the advancements and implementations of healthcare in AI. Hear from industry lead experts, connect with healthcare professionals, enjoy interactive Q&A discussions, and much more.

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Ireland is open: The biologics boom boosting the Irish economy

pharmaphorum

The life sciences industry has an important role in the Irish economy, with sectors such as biologics booming across the country. Rory Mullen, head of biopharma at Ireland’s economic development agency IDA Ireland tells pharmaphorum why business is blossoming in the Emerald Isle. With an attractive corporate tax rate and the youngest workforce in the EU, Ireland continues to be a popular destination for life science companies to settle.

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Sanofi, MIT Jameel Clinic join to advance health research with AI

Outsourcing Pharma

The collaboration between the Jameel Clinic and pharma firm will harness artificial intelligence and machine learning in developing health solutions.

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How Much Rent Can I Afford in 2021?

That Frugal Pharmacist

Asking yourself how much rent you can afford is the first step when you plan to find a new home. Answering this question can be the starting point to deciding where you want to live and what kind of place you want to rent. Key point: this information is for general use purposes. If you … How Much Rent Can I Afford in 2021? Read More ».

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Cyclobenzaprine And The Prescribing Cascade

Med Ed 101

Cyclobenzaprine (podcast episode) is a skeletal muscle relaxant that is most commonly used for muscle spasms and back pain. It definitely has some potential adverse effects that I have seen lead to the prescribing cascade. Here’s a rundown of medications that may help you recognize cyclobenzaprine and the prescribing cascade. Dry Mouth Some of the […].

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Labour accuses government of cronyism in COVID-19 contracts

pharmaphorum

The UK government’s massive spending on the coronavirus pandemic response has been “rife with conflicts of interest”, says the opposition Labour Party, and an independent watchdog should be set up to oversee procurement contracts. That was the message delivered by shadow Cabinet Office minister Rachel Reeves in a speech yesterday which claimed almost £2 billion of the £23.1 billion public sector spend on the pandemic went on contracts that were awarded to “Conservative friends and donors”

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PwC joins Medicines Manufacturing Innovation Centre

Outsourcing Pharma

The global professional services firm has signed on the newest partner in the collaboration, aimed toward promoting innovation in pharma manufacturing.

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February Ramblings – Cautionary Insights on the Road to Freelance

That Frugal Pharmacist

I’m swamped. That’s how it feels at least. Trying to do a quick little blog check in here about some of the things I am thinking and feeling as I progress on the road to freelance income. I can’t decide if I have taken on too many things or if this is just a season … February Ramblings – Cautionary Insights on the Road to Freelance Read More ».

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Top 5 CYP2C19 Drug Interactions

Med Ed 101

Here’s a list of some of the most common CYP2C19 drug interactions that I have seen in clinical practice. Citalopram and Omeprazole Interaction Omeprazole can significantly increase the concentration of citalopram. Because of this drug interaction, there is a greater risk for citalopram toxicity and QTc prolongation. Omeprazole inhibits CYP2C19 which is an important breakdown […].

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performance-io strikes multimillion-pound deal with STEM’s Rob Wood

pharmaphorum

Rob Wood has acquired a large minority stake in performance-io through a multimillion-pound deal that will see him join the specialist online performance marketing agency’s executive board. A former AstraZeneca director, Wood founded commercial and medical benchmarking firm STEM in 2007 before selling it to UDG Healthcare for £84 million in 2016. Since leaving that company he has invested in a number of disruptive technology-driven pharma service providers. performance-io ’s founder and CEO Matt

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Immunity-centric biotech firm lands $60m in Series A funding

Outsourcing Pharma

Immunai has secured a total of $80m in funding to develop and promote its efforts to harness machine learning to fuel advancement of novel immunotherapies.

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Synairgen’s inhaled COVID-19 treatment included in US trial

Pharma Times

Trial is sponsored by the US National Institute of Allergy and Infectious Diseases (NIAID)

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Novartis antibiotic retreat doesn’t stop Sandoz buying GSK drugs

pharmaphorum

Novartis exited novel antibiotics R&D three years ago, but is clearly still interested in the category – its Sandoz unit has just spent $350 million buying GlaxoSmithKline’s cephalosporin franchise. . The deal covers global rights to three brands – Zinnat (cefuroxime axetil), Zinacef (cefuroxime) and Fortum (ceftazidime) – which are sold in more than 100 markets around the world and had sales of around $140 million last year.

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Stay calm and carry on: How to implement the updated ABPI code

pharmaphorum

Don’t panic – that’s the message from one ABPI code expert who tells Amanda Barrell it’s time to take stock and prioritise. Compliance managers have less than six months to rewrite processes and procedures in line with the updated ABPI code of practice before it becomes enforceable in July. But it doesn’t all have to be done at once, says Dr Rina Newton, managing director at code consultancy firm, CompliMed.

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BMS finally gets FDA OK for liso-cel, sets $410k launch price

pharmaphorum

Bristol-Myers Squibb finally has FDA approval for its CAR-T therapy liso-cel, which has been cleared by the US regulator as Breyanzi for certain forms of large B-cell lymphoma. The green light comes too late for holders of the contingent value right (CVR) BMS offered as a sweetener to its takeover of Celgene, which lapsed because liso-cel didn’t get approval by the deadline of 31 December.

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Ipsen’s John Chaddock on making neurotoxins a priority for healthcare systems

pharmaphorum

Injected neurotoxins can be incredibly potent in treating spasticity from neurological diseases, but the field doesn’t always get the attention it needs. Ipsen’s John Chaddock tells us why the company is investing heavily in neurotoxin research and how he hopes to raise awareness among young scientists and the NHS. When the COVID-19 pandemic first hit, countries were forced to make difficult decisions about which healthcare services to continue and which to halt as systems came under immense st

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VPAS: Achievement so far on objectives for the economy and innovation

pharmaphorum

In the third part of this series taking stock of t he 2019 Voluntary Scheme for Branded Medicines Pricing and Access objectives, Leela Barham looks at the third VPAS objective that relates to the economy and innovation. The objectives for the economy and innovation are to: deliver a net benefit to the UK economy overall; and. support the life sciences industry across the UK and future innovation.

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Increasing patient engagement with UK clinical trials

pharmaphorum

Pharma companies face many challenges when involving patients in the design of clinical trials – but doing so can have huge benefits further down the line, improving the sustainability and quality of research. Patient engagement can help address long-running industry issues, such as recruitment and retention, as well as reducing the need for additional trial protocol amendments.

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Generic inhaled steroid could treat early COVID-19, study finds

pharmaphorum

The generic respiratory drug budesonide could be an option to treat COVID-19, a small scale clinical study has suggested. Marketed in the past by AstraZeneca as Pulmicort, budesonide is an off-patent inhaled steroid and could be used to prevent the risk of people getting seriously ill with the disease, if taken within the first week of developing symptoms.

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Heat Bio’s shares ignite on Opdivo combination data in NSCLC

pharmaphorum

The pairing of Heat Biologics’ lead drug HS-110 with Bristol-Myers Squibb’s blockbuster checkpoint inhibitor Opdivo has boosted survival in patients with non-small cell lung cancer (NSCLC), sending the biotech’s share price skywards. . Interim data from a phase 2 trial of Heat’s off-the-shelf cell therapy with Opdivo (nivolumab) showed that patients treated with the duo as a second-line therapy had a survival benefit, particularly in patients who hadn’t previously had checkpoint inhibitor therap

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Pulse Infoframe Releases Registry for Patient Advocacy Groups

pharmaphorum

Launching a rare disease patient registry often requires patient advocacy groups to design a registry themselves or pay for an expensive customized solution. With the launch of Rare Central , Pulse Infoframe offers patient advocacy groups an on-ramp to collecting real-world data, including natural history data, disease-specific data, and patient-reported outcomes.

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ViiV’s Rukobia cleared in EU as rescue HIV therapy

pharmaphorum

The European Commission has given a green light to the use of ViiV Healthcare’s Rukobia as a treatment for people with HIV that has developed resistance to other antiretroviral therapy (ART). . The first-in-class HIV attachment inhibitor is cleared for use as an add-on therapy to other ARTs in adults “for whom it is otherwise not possible to construct a suppressive antiviral regimen,” according to ViiV, which is majority-owned by GlaxoSmithKline.

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A study to avoid chemotherapy in patients with early HER-2+ breast cancer

pharmaphorum

MEDSIR , a global company dedicated to independent clinical research in oncology, has initiated the PHERGain II clinical trial to demonstrate that in patients with HER2-positive early breast cancer with a good prognosis, a chemotherapy-free therapeutic approach can be as effective as the current standard of care, which involves the use of this generally more toxic treatment.

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3rd Microbiome Movement – Maternal & Infant Health Summit

pharmaphorum

Harness the Maternal-Infant Microbiome, Establish New Mechanisms of Action, and Develop Breakthrough Health Products that Proactively Prevent Disease Risk. Returning for another year, the 3rd Microbiome Movement – Maternal & Infant Health Summit will unite industry and academics in the exploration of preventative and therapeutic treatment of the microbiome during pregnancy and early life.

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China approves Sinovac’s coronavirus vaccine

pharmaphorum

China’s national regulator has approved Sinovac Biotech’s COVID-19 vaccine for use by the general public. This is the second vaccine approved by China’s National Medical Products Administration (NMPA). Both of the vaccines, along with another experimental vaccine from Sinopharm, have been used in China’s vaccination programme. More than 31 million doses have been administered, mainly targeting groups at higher infection risks, while a fourth experimental vaccine from CanSino Biologics has been g

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AZ’s next-generation COVID-19 vaccine could be ready in autumn

pharmaphorum

AstraZeneca is aiming to get a next-generation vaccine targeting emerging variants approved and into the arms of patients by the autumn, company representatives said in a press conference. Mene Pangalos, executive vice president of BioPharmaceuticals R&D, said work has already begun to tweak the shot developed with Oxford University to combat the new variants, which could be in the arms of patients by autumn.

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EU-funded project encourages use of simulation in drug development

pharmaphorum

A new EU-funded project called In Silico World aims to encourage the use of simulation for drug and medical device development. The project is coordinated by the University of Bologna and funded by the European Union’s Horizon 2020 research and innovation programme that involves more than a dozen partner institutions, including Italian startup InSilicoTrials.

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BMS’ MS pill gets funding in Scotland after rejection in England by NICE

pharmaphorum

Scotland’s drugs cost-effectiveness body has recommended Bristol-Myers Squibb’s Zeposia multiple sclerosis pill, setting a potential north-south access divide following a draft rejection in England by NICE last month. There are a range of MS drugs on the market but Zeposia does not have the common unpleasant gastrointestinal side effects that can occur with Biogen’s Tecfidera.