Sat.Feb 12, 2022 - Fri.Feb 18, 2022

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Collaborative approach to closing the digital health gap is needed

pharmaphorum

The pandemic-induced transition to digital health is, according to the Nuffield Trust, contributing to an “inverse care law” that’s compounding existing health inequalities. But, as demonstrated by initiatives like the Telehealth Equity Coalition (TEC), the sector is taking a united stand against inequitable access. Technological solutions, from online clinics to app-based long-term condition management, have long been hailed as a solution to problems such as limited capacity and low patient aut

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Expect growth, innovation in digital health landscape: BCG Digital Ventures

Outsourcing Pharma

In its forward-looking report on digital health, the consulting outfit offers predictions on what changes are ahead and how they might impact the field.

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Pharma Franchise Business Is Beneficial For the Indian Pharmaceutical Market

Fossil Remedies

PCD Pharma Franchise Business. Why are more aspirants willing to make a career in the field of pharmaceuticals? It is because the business is not only promising, but it is going to remain profitable for many years. People have become health conscious and they want to maintain fitness. Also, the recent Covid-19 outbreak has also changed the scenario.

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QED Environmental Systems Ltd MD becomes Co-Chair of CoGDEM Industry Subgroup

Pharma Mirror

Dean Kavanagh, Managing Director of QED Environmental Systems Ltd in the UK, has been appointed Co-Chair of the Council of Gas Detection and Environmental Monitoring (CoGDEM) Industry Subgroup. Dean will chair the Sub-group with Rob White, Sales Director of DD Scientific, with both chairs taking up their appointments early in 2022. The CoGDEM Industry Subgroup is one of the most influential steering groups, with meetings scheduled three times a year.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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NHS said to be central to Moderna interest in UK facility

pharmaphorum

Moderna is reportedly in late-stage negotiations with the UK government that could result in a new research and manufacturing facility being set up in the biotech ‘golden triangle’ between London, Oxford and Cambridge. The development has been prompted by a desire on the behalf of the US biotech to collaborate with the NHS, according to a report in the Financial Times, which cites people familiar with the matter.

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Clinical research trends include increased emphasis on study design: Advarra

Outsourcing Pharma

An expert from the institutional review board services company advises what trends to look for in the clinical trial industry over the course of coming months.

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7 Problems with Using Borosilicate Glass to Package Drugs

Pharma Mirror

By Christopher Weikart, Chief Scientist, SiO2 Materials Science Even though drugs are meant to save lives, the primary packaging used for delivering drug therapies and vaccines may actually be putting us in danger. The pharmaceutical industry works hard to create cutting-edge drugs to save lives and keep people healthy. From research to clinical trials, to go-to-market, drug makers are constantly seeking out new drug technologies and approaches to treat everyday illnesses and to end global pande

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Pharma pollution ‘threatens world environment, health’; study

pharmaphorum

One in four of the world’s rivers are polluted with potentially toxic levels of pharma compounds, according to a new study. The findings point to a “threat to environmental and global health,” say the scientists, who found that paracetamol, antibiotics epilepsy drug carbamazepine, metformin for diabetes and other compounds like caffeine and nicotine were found in samples from around the world – including in Antarctica.

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Domainex, Parkinson’s UK team up to advance neuroinflammation program

Outsourcing Pharma

The institute and the research/support organization will collaborate on development of novel therapies aimed at treating the central nervous system disorder.

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MYELOID CELL TARGETING THERAPEUTICS: BUDDING THERAPY AGAINST CANCER

Roots Analysis

Myeloid cells represent a group of cells containing granulocytes, monocytes, macrophages, mast cells and dendritic cells, which play a key role in innate immunity. These cells are found in abundance in the tumor microenvironment and inflamed areas. The tumor recruits and modulates endogenous myeloid cells to tumor-associated macrophages, dendritic cells, myeloid-derived suppressor cells and neutrophils, to sustain an immunosuppressive environment.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Chronic Disease Solutions: Spotlight on COVID-19 and its Impact on Heart Disease

PharmD Live

By Richard Korecky, PharmD, BCGP. COVID-19 has profoundly changed the world we live in today and will continue to leave an indelible mark long after the pandemic has ended. One area of concern for both health care providers and their patients is the long-term effect of COVID-19 infection on patients with chronic diseases. Acute cardiac injury has been a well-documented feature of infection with SARS-CoV-2, which causes COVID-19 among patients requiring hospitalization.

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Dupixent falls short in phase 3 chronic spontaneous urticaria trial

pharmaphorum

Sanofi and Regeneron have reported disappointing results in a trial of Dupixent in people with chronic spontaneous urticaria (CSU) who don’t respond to the only approved biologic treatment, Novartis/Roche’s Xolair. . CSU is a severe form of hives that affects around 1% of the global population, causing severe itching and swelling that can last for weeks at a time and resist even very high doses of antihistamines, the standard, first-line therapy for the condition.

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Tech, talent, and partnerships elevate data management: ICON

Outsourcing Pharma

In this second of a two-part series, experts from the clinical research organization share thoughts on how data management technology, personnel, and partnerships have evolved.

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3 Exosome Services And Technologies For Skin Regeneration

Pharma Mirror

The importance of exosomes in skin cell regeneration has been extensively researched over the past few years. Functions involving the fibroblasts, forming of new blood vessels, and controlling the localized inflammatory response of the skin are all benefits of their use. Exosomes have another essential function, and that would be intercellular communication.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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The history of pharmaceutical microbiology

Pharmig

Everyone wants to know where they come from, and microbiologists are no different. But were we grown in a petri dish. The post The history of pharmaceutical microbiology appeared first on Pharmig.

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Bayer triples sales forecast for prostate cancer drug Nubeqa

pharmaphorum

Bayer now says it expects to make €3 billion in sales for its prostate cancer treatment Nubeqa, up from an earlier estimate of €1 billion, after reviewing new data for the drug in metastatic hormone-sensitive tumours. The optimistic assessment of the revenue potential for androgen receptor inhibitor Nubeqa (darolutamide) follows the publication of the results of the phase 3 ARASENS trial in the New England Journal of Medicine.

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Collaboration to advance development of cancer therapies

Outsourcing Pharma

Cullinan Oncology has formed a strategic partnership with the Icahn School of Medicine at Mount Sinai to research and develop targeted therapies for cancer.

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The 4 Best Ways To Increase Productivity In Your Lab

Pharma Mirror

Although many labs are doing cutting-edge research and finding new ways to improve life in this world, they aren’t always the picture of productivity. Unfortunately, some labs are not very well organized internally and often could find ways to be more productive. Resources are often very limited so it makes sense to work on being more productive and wasting fewer resources to get the job done.

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Putting user-needs at the heart of a multi-agency advisory service for artificial intelligence and data-driven technologies

NICE

NICE is working in partnership with the Care Quality Commission, Health Research Authority and Medicines and Healthcare products Regulatory Agency to deliver a multi-agency advisory service (MAAS) for developers and adopters of data-driven technologies, such as artificial intelligence (AI). This innovative new cross-regulatory service will provide support on the regulation and evaluation of AI technologies in health and care.

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Merck will assess Quris’ AI ‘patient-on-a-chip’ drug safety

pharmaphorum

German drugmaker Merck KGaA has reached an agreement to pilot an artificial intelligence platform developed by Quris that aims to identify potential safety problems with new therapeutic candidates as early as possible in the drug discovery process. Quris’ BioAI safety prediction platform – which is based on human tissue samples on chips, nanosensors and machine learning – will be compared to traditional in vitro and in vivo laboratory techniques for spotting toxicity.

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Navigating Psychedelics and Psychotropics

The Spirit Pharmacist

Bridging the Gap: Navigating Psychotropics and Psychedelics. As psychedelics therapies rapidly emerge as treatments for mental health conditions, many are interested in use. However, some psychotropic medications can interfere with benefits or increase risks. Sometimes these interactions are significant enough to warrant taper and discontinuation, whereas sometimes they aren't.

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3 Steps to More Sustainable Medical Labs

Pharma Mirror

The concept of sustainability is gaining more traction in society with each passing day. Human activities pose numerous risks to the environment, so many industries and sectors are looking to become more sustainable. Can medical labs switch to greener practices without affecting the quality and accuracy of their output? The answer is a resounding yes.

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Better research, faster: NIHR launch new funding call to address NICE research recommendations

NICE

What is a NICE research recommendation? As NICE develops any of its guidance products, we identify gaps and uncertainties in the evidence base which could benefit from further research. The most important unanswered questions are developed into research recommendations. How do NICE & NIHR work together? NIHR have been screening NICE guidance for nearly 20 years to identify topics suitable for commissioning research.

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AZ’s lupus drug Saphnelo cleared in EU, challenging GSK’s Benlysta

pharmaphorum

AstraZeneca’s Saphnelo has become the first new drug to be approved to treat the autoimmune disease systemic lupus erythematosus (SLE) in the EU for more than 10 years. The European Commission has cleared the type I interferon receptor antagonist antibody as an add-on therapy to standard treatment for adults with moderate to severe SLE, four years after a miss in a phase 3 trial put the future of the drug in doubt.

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Bayer program streamlines clinical trial process, site relationships

Outsourcing Pharma

Created via a joint effort with EY, the pharmaceutical company launched ASPIREs, a program intended to improve its clinical trial processes in numerous areas.

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Comparison of Fish Oil Products For Pharmacists

Med Ed 101

The interest surrounding fish oil products has been around for decades, and we are still learning about many of their mechanisms and potential benefits. In the post below, we provide a comparison of fish oil products and break down the family of omega fatty acids. Omega-3 fatty acids in particular have been researched with regards […]. The post Comparison of Fish Oil Products For Pharmacists appeared first on Med Ed 101.

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Scientists discover immune cell surveillance mechanism

Pharma Times

Francis Crick Institute and King’s College London collaborate to identify specialist cells which protect DNA

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Why was R&D productivity up in 2021?

pharmaphorum

A recent report has found that R&D productivity rose vertiginously during 2021, but how much of this was organic and how much can be attributed to the pandemic? In this feature, Ben Hargreaves looks at all of the factors involved and how the increased return can be maintained. The pharma industry has had a difficult time solving the issue of achieving greater productivity without significantly increasing the cost it takes to discover and commercialise new products.

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Tech Innovations: February 2022

Outsourcing Pharma

This monthâs list of announcements about technology, funding, and more includes Medable, Clarify Health, Thermo Fisher Scientific, and other key companies.

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Reducing Polypharmacy in BPH

Med Ed 101

BPH is a common problem as our male patients age. Symptoms of urinary retention and frequency can often be very problematic for patients which results in the use of medications. We also run into polypharmacy concerns in many patients as they get older with a growing number of health conditions. Here are some thoughts on […]. The post Reducing Polypharmacy in BPH appeared first on Med Ed 101.

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Data day: Trial results deliver hope for prostate cancer patients

Pharma Times

New combination treatment can significantly reduce the risk of death among prostate cancer patients

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Stem cell therapy ‘cures’ first woman with HIV, say researchers

pharmaphorum

A woman with HIV who received a stem cell transplant to treat acute myeloid leukaemia (AML) appears to have been cured of the infection according to US researchers. The case study described at the Conference on Retroviruses and Opportunistic Infections (CROI) this week involved a mixed-race woman who had been on antiretroviral therapy (ART) for four years before being diagnosed with AML.

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Merck restructures to strengthen CDMO business

Outsourcing Pharma

Darmstadt, Germany headquartered, Merck KGaA, is restructuring its life sciences business.

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ADC Cytotoxic Payloads / Warheads and Rise in its Demand

Roots Analysis

With six approved drugs, namely POLIVY (2019), LUMOXITI (2018), BESPONSA® (2017), MYLOTARG (2017, reapproval), KADCYLA® (2013) and ADCETRIS® (2011), and more than 300 candidates in the pipeline (clinical / preclinical stages), antibody drug conjugates (ADCs) have emerged as a promising class of therapeutics for the treatment of various disease indications.

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