Wed.Jan 18, 2023

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Three-Dose Hepatitis B Vaccine Regimen Can Protect Those With HIV

Drug Topics

Previously hepatitis B vaccines have offered lower levels of protection for people living with HIV. New research indicates that a 3-dose series could offer much better protection.

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HIV vaccine being developed by Johnson & Johnson fails clinical trial

STAT

Yet another experimental HIV vaccine has failed. The National Institute of Allergy and Infectious Diseases reported Wednesday that a Phase 3 clinical trial of a vaccine was stopped because the vaccine was ineffective at preventing HIV infection. The vaccine was being developed by Janssen, the vaccine division of Johnson & Johnson.

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Antipsychotic Prescriptions on the Rise Among Pediatric Patients

Drug Topics

A recent study found a rise in the prevalence of antipsychotic prescriptions among pediatric patients and noted which antipsychotics were most commonly used for specific indications.

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Mix-it-yourself Wegovy? Some are trying risky sources for weight-loss drugs

STAT

With a few clicks, Daniel added the chemical to his online cart and ordered it. In less than a week, a vial containing white powder arrived at his house. He used a syringe to measure out sterile water and eject it into the vial to dissolve the powder. Then, with a different syringe, he drew up about a quarter of a milliliter of the solution and injected it into his lower abdomen.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Tdap Vaccine Approved by FDA for Use During Pregnancy for Pertussis Prevention

Drug Topics

The FDA has approved another Tdap vaccine option for use during pregnancy to prevent pertussis, otherwise known as whooping cough.

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Artificial Intelligence Tool Reflects Risk of Cognitive Decline, Alzheimer Disease Based on Brain Age

Pharmacy Times

The model can predict the chronological ages of cognitively normal participants with an average absolute error of 2.3 years, which is about 1 year more accurate than an existing model.

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Study: Increased Coffee Consumption May Reduce Severity of Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes

Pharmacy Times

Individuals with higher caffeine levels were less likely to have liver fibrosis, while higher levels of non-caffeine coffee components were associated with reduced fatty liver index scores.

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U.S. plans crackdown on nursing homes that sedate patients with unnecessary antipsychotics

STAT

WASHINGTON (AP) — The federal government says it will begin a targeted crackdown on nursing homes’ abuse of antipsychotic drugs and misdiagnoses of schizophrenia in patients. The Centers for Medicare and Medicaid Services is launching investigations this month into select nursing homes, aimed at verifying whether patients have been properly diagnosed with the psychiatric disorder.

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Clinical Trial Confirms Highest Reported Sensitivity Results for At-Home, Noninvasive Colorectal Cancer Screening Test

Pharmacy Times

The stool-test is the first-of-its-kind to detect CRC in adults aged 45 to 49 years, with a premarket approval submission planned to be sent to the FDA early in 2023.

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STAT+: Hip and knee replacements go better when performed by high-volume surgeons, new study finds

STAT

A new study underscores the importance of the adage “practice makes perfect,” especially when it comes to surgery. It’s long been understood that the frequency at which surgeons perform and hospitals host complex procedures has a bearing on how patients fare, but the study from the Clarify Health Institute makes the link even clearer.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Sublingual Ketamine Demonstrated to Be Safe, Effective for Patients with Treatment-Resistant Depression

Pharmacy Times

Research highlights that 6 doses of sublingual ketamine may be more effective than 3 doses, however both can ameliorate symptoms of anxiety and depression.

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New Jefferson Health program enables clinical, academic nurses to partner on research

Fierce Healthcare

New Jefferson Health program enables clinical, academic nurses to partner on research agliadkovskaya Wed, 01/18/2023 - 14:16

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HHS needs better oversight of research that alters pathogens, government watchdog says

STAT

WASHINGTON — The health department’s oversight of research that could enhance dangerous pathogens has vague parameters, a lack of transparency, and “does not fully meet the key elements of effective oversight,” a nonpartisan federal watchdog found in a report released Wednesday. The Government Accountability Office’s report is a precursor to a debate that will heat up at the National Institutes of Health over the next few weeks.

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Black patients get better care when nurse practitioners have full practice authority: study

Fierce Healthcare

Black patients get better care when nurse practitioners have full practice authority: study. fdiamond. Wed, 01/18/2023 - 15:46.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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UK medical cannabis manufacturer granted GMP registration

European Pharmaceutical Review

The first good manufacturing practice (GMP) registration of a UK pharmaceutical facility for high Δ9-tetrahydrocannabinol (THC) cannabis active pharmaceutical ingredient (API) has been granted since the legalisation of medical cannabis in 2018. Celadon Pharmaceuticals’ Midlands site is now registered by the UK Medicines and Healthcare products Regulatory Agency (MHRA) for GMP manufacturing.

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Healthcare ranked lowest for employee satisfaction, Qualtrics survey finds

Fierce Healthcare

Healthcare ranked lowest for employee satisfaction, Qualtrics survey finds aburky Wed, 01/18/2023 - 16:40

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Cough, Cold, Flu and Allergy products see gains as consumers endure the tripledemic

Drug Store News

The the tripledemic of viral infections took hold even before winter began, and people are still looking for products that offer fast relief, provide multiple benefits and are easy to take.

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STAT+: Verily leans into Onduo as it looks to enter the lucrative world of running medical research

STAT

The new, streamlined Verily will have one very recognizable component: its virtual care company Onduo, whose prodigious data collection from chronic disease patients will help power Verily’s significant push into research into new drugs, devices, and treatment approaches. Onduo was largely absent from a memo released last week in which Verily’s new CEO said that the Alphabet spinout was cutting 15% of its workforce and focusing on efforts that could either improve clinical research

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Health insurers well-positioned to weather inflation, utilization shifts in 2023: Fitch

Fierce Healthcare

Health insurers well-positioned to weather inflation, utilization shifts in 2023: Fitch. pminemyer. Wed, 01/18/2023 - 16:51.

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Governing Principles for Successful Biotechnology Companies

PharmExec

Pete O'Heeron, founder, chairman, and CEO of FibroBiologics, explains the key principles that biotechnology companies should follow.

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AbbVie, Novartis and more win national coverage in China even as Pfizer's Paxlovid gets left out

Fierce Pharma

AbbVie, Novartis and more win national coverage in China even as Pfizer's Paxlovid gets left out. aliu. Wed, 01/18/2023 - 14:00.

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Opinion: Biopharma leaders helped save democracy. Now what?

STAT

The rule of law must be upheld for free societies and free markets to flourish, and only a well-functioning democracy offers the levers for rational majorities to prevail. Americans support causes and candidates. We debate and organize. Then we vote, respecting the outcome, knowing that soon enough, we’ll have the sacred right to do so again.

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4 ways to save on weight-loss medications

The Checkup by Singlecare

Obesity is a pervasive problem in the United States. Nearly 1 in 3 adults is considered overweight, and more than 2 in 5 adults are obese , according to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). One out of every 11 adults meets the criteria for severe obesity, a body mass index of 40 or greater. . For many years, experts recommended diet and exercise alone, “but they simply aren’t effective for the vast majority of individuals affected by obesity,” says gastro

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Opinion: Leaders at Davos need to pay attention to the crossroads of climate change, health, and security

STAT

As CEOs and world leaders gather for the World Economic Forum in Davos, Switzerland, this week, they might be surprised to see less snow out of the window than usual on the country’s luminous peaks. Record-breaking temperatures in the Alps are just one sign of the effect climate change is having on planet Earth. Longer rainy seasons and a warmer climate are leading to more dengue fever, the worsening famine in the Sahel caused in part by erratic rainfall driven by climate change, and temp

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Providers' price hikes push patients to defer care, rely on payment plans, surveys say

Fierce Healthcare

Providers' price hikes push patients to defer care, rely on payment plans, surveys say. dmuoio. Wed, 01/18/2023 - 12:15.

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Pioneering oral treatment for myeloma receives green light from NICE

Hospital Pharmacy Europe

The National Institute for Health and Care Excellence (NICE) has approved the use of ixazomib (Ninlaro®) in combination with lenalidomide (Revlimid®) and dexamethasone (IRD) – the first oral triplet treatment for myeloma , which kills 3000 people in the UK each year. IRD is aimed at patients whose cancer has returned for a third or fourth time and has been shown to increase average survival by 10 months.

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Walmart expands Associate-to-Driver pilot program

Drug Store News

Through this expanded pilot, Walmart associates in stores, distribution centers, fulfillment centers and transportation offices within a 50-mile radius of a participating transportation office will be eligible to apply to the Associate-to-Driver prog

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STAT+: Pharmalittle: HIV vaccine study is stopped early; Merck has a plan to combat carcinogen found in diabetes drugs

STAT

Top of the morning to you. The middle of the week is upon us and, since you made it this far, why not forge ahead? After all, there is always light at the end of the proverbial tunnel. You never know what you may accomplish. So please join us as we celebrate this notion with a cup or three of delicious stimulation. Our choice today is blueberry cobbler.

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Teladoc Health lays off 300 employees, 6% of its non-clinician workforce

Fierce Healthcare

Teladoc Health lays off 300 employees, 6% of its non-clinician workforce. aburky. Wed, 01/18/2023 - 13:22.

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Why early participant engagement is now a top priority in genetic disease research

pharmaphorum

In 2016, scientists behind a study called the Resilience Project analysed genetic data from 589,000+ people and found 13 adults who carried genetic variants that should have resulted in serious – even deadly – childhood disease, but who were apparently healthy. The DNA of these so-called ‘genetic superheroes’ may contain clues about how to treat severe disease.

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Bovine Collagen May Preserve, Restore Soft Tissue for Moderately, Heavily Exudating Wounds

Pharmacy Times

Soft tissue reconstruction solutions can leverage a patient’s natural healing response.

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FDA fires back at conservative group's lawsuit over abortion pill approval

Fierce Pharma

FDA fires back at conservative group's lawsuit over abortion pill approval. zbecker. Wed, 01/18/2023 - 11:30.

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January 2023 Over-the-Counter Product News

Pharmacy Times

Products range from natural eye relief to sleep aid.

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Servier, Taiho score in phase 3 colorectal cancer trial to support Lonsurf combo nod

Fierce Pharma

Servier, Taiho score in phase 3 colorectal cancer trial to support Lonsurf combo nod. kdunleavy. Wed, 01/18/2023 - 15:13.

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