Wed.Sep 07, 2022

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2022-2023 Flu Season Vaccination Recommendations for Children and Adolescents

Drug Topics

Keep your pharmacy vaccine-ready for your youngest patients with the most current influenza vaccination information from the American Academy of Pediatrics.

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NSAIDs Linked to Thousands of Heart Failure Hospitalizations Among Patients With Type 2 Diabetes

Pharmacy Times

A recent study suggests that infrequently taking non-steroidal anti-inflammatory drugs, especially ibuprofen, with type 2 diabetes can increase the risk of first-time heart failure and hospitalization.

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Trending Sources

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Waste Problem Shows COVID-19 Vaccines Aren’t Just a Dime a Dozen

Drug Topics

When it comes to the COVID-19 vaccine, independent pharmacies are being set up to fail by federal health partners.

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Study: Dolutegravir-based Antiretroviral Therapies for HIV-1 Effective in Pregnancy

Pharmacy Times

Dolutegravir is a more recently approved ART that is a part of a once-a-day regimen found to be more effective, easier to tolerate, and less likely to create new drug resistance in people with HIV-1 compared with other antiretroviral drugs.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Drug Testing Challenges Emerge With CBD Product Use

Drug Topics

Even “THC-free” cannabidiol products may contain trace amounts of THC.

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Accelerated Changes in Pharmacy Make Advanced Practice Essential for Pharmacists, Technicians

Pharmacy Times

The COVID-19 pandemic accelerated many changes in the pharmacy field, but maintaining that momentum and working together will be essential for the future growth of pharmacy.

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More Trending

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STAT+: Why Illumina has a merger mess of its own making

STAT

For Illumina, the leading maker of DNA sequencing equipment, there was bad news and worse news Tuesday. The bad news: The European Commission said it was blocking Illumina’s $8 billion acquisition of Grail, a firm focused on the early detection of cancer. The worse news? In its press release on the ruling, Illumina acknowledged that, although it will appeal, that may not prevent the European Commission from forcing it to divest Grail, which it purchased before regulatory approvals were in

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Caffeine Metabolite Slows Progress of Myopia in Children

Drug Topics

Using 7-methylxanthine may be key to slowing myopia in pediatric cases.

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Bridge Bio will use Brainomix AI in lung fibrosis trial

pharmaphorum

Brainomix has reeled in another pharma partner for its artificial intelligence-powered biomarker software, used to track the performance of therapeutic interventions in clinical trials. South Korea’s Bridge Biotherapeutics has signed up to use the UK medtech firm’s e-ILD software package in a phase 2 trial of BBT-877, its experimental therapy for serious lung disease idiopathic pulmonary fibrosis (IPF).

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Survey: 44% of Americans Worry That Medication Prices Could Lead to Increased Debt

Pharmacy Times

One-third of participants who have used prescriptions think that mail-order pharmacies would help reduce drug costs, according to HealthCare.com.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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As masks are shed, a routine visit to a medical office can pose Covid risks for some patients

STAT

In May, Sarah Fama had to get blood work done before refilling a prescription for an autoimmune disorder. Because her condition put her at high risk for Covid-19, and she lives with her parents, both in their 80s, she checked the lab’s website, which stated that masks were required inside. When she arrived, she was reassured by a sign on the door that said the same thing.

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Diagnosis and Management of C. difficile Infection (CDI) in Patients with Inflammatory Bowel Disease

Pharmacy Times

Dr. Abraham discusses importance of differential diagnosis of C. difficile infection (CDI) in patients with IBD and how both IBD and CDI should be managed.

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What CBD Brings to Women's Health

Drug Topics

Alex Capano, DNP, CRNP, FNP-BC, discusses what cannabidiol can do in women's health from pelvic pain to fertility to cancer.

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Study: Patients with Certain Heart Conditions Should be Given Antibiotics Before Invasive Dental Surgery

Pharmacy Times

Researchers suggest that dentists who do not administer antibiotics to high-risk patients for infective endocarditis could be risking the patient’s life.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Stress and depression are better long Covid indicators than physical comorbidities, new study says

STAT

Studies have repeatedly suggested that physical conditions like immunosuppression and hypertension can increase a person’s risk not only for severe Covid but also long Covid. But in a new study , researchers found that psychological stressors such as depression, anxiety, and loneliness were more predictive of Covid patients’ likelihood of experiencing long Covid than classically associated physical factors.

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Results of New Harvard, Tufts Study Link Colorectal Cancer in Men to Ultra-Processed Foods

Pharmacy Times

Processed meats and products high in added sugars and low in fiber contribute to weight gain and obesity, which is an established risk factor.

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Judge invalidates parts of the ACA that mandate health coverage of many preventive services and drugs

STAT

A federal judge in Texas has ruled that parts of the Affordable Care Act mandating health insurance companies cover many preventive services and drugs for free are unconstitutional. Judge Reed O’Connor also said the ACA’s requirement that health plans cover HIV pre-exposure prophylaxis, or PrEP, at no cost violates religious freedom law.

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Study: Oral Insulin Absorption Rate Is as Effective as Injected Insulin

Pharmacy Times

Investigators report that they have seen nearly 100% of the hormone from their tablets going straight into the liver of rats.

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India grants approval for Bharat Biotech’s intranasal Covid-19 vaccine

Pharmaceutical Technology

Indian company Bharat Biotech International has secured approval from Central Drugs Standard Control Organisation (CDSCO) under Restricted Use in Emergency Situation for its intranasal Covid-19 vaccine, iNCOVACC (BBV154), for usage in people aged 18 years and older. A recombinant replication-deficient adenovirus vectored vaccine, iNCOVACC has a prefusion stabilised spike protein and is claimed to be the first intranasal vaccine globally to obtain primary two-dose schedule approvals.

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EU regulators release new workplan for accelerating clinical research

European Pharmaceutical Review

The 2022-2026 workplan of the initiative Accelerating Clinical Trials in the EU ( ACT EU ) has been published by the European Commission (EC), Heads of Medicines Agencies (HMA) and European Medicines Agency (EMA). Launched in January, ACT EU aims to transform how clinical trials are initiated, designed and run, building off of the Clinical Trials Regulation (CTR) and Clinical Trials Information System (CTIS) which became applicable in the same month.

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Opinion: The FDA needs to be more flexible in assessing treatments for rare diseases, like the one that seemed to help my son

STAT

Every time I read about clinical trials testing possible treatments for rare diseases, I think of my son, Ty, whose brief but successful foray into such a trial highlights their value and their devastating limitations. Ty was born in Pocatello, Idaho, in October 1996 with green eyes, a big personality, a great sense of humor, and — as we finally learned eight years later — a rare and fatal disease called Niemann-Pick type C.

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Clinical Overview: Treatment of Schizophrenia, Schizoaffective Disorders

Pharmacy Times

The mainstay of treatment for schizophrenia and schizoaffective disorder includes antipsychotics.

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STAT+: Tobacco giant Philip Morris is investing billions in health care. Critics say it’s peddling cures for its own poison

STAT

A new health care company was quietly incorporated last month, with plans to leverage cutting-edge inhalation technology and oral delivery expertise to treat everything from neurology to cardiovascular emergencies. The multibillion-dollar company, Vectura Fertin Pharma , stands out not simply for its ambitions, but because of its financial backer: Philip Morris International, the tobacco behemoth whose cigarettes are sold in more than 180 countries.

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Gilead claims first CAR-T approval for leukaemia in older adults

pharmaphorum

Gilead Sciences’ Kite Pharma unit has carved out a niche for its CD19-targeted CAR-T therapy Tecartus in acute lymphoblastic leukaemia (ALL) in Europe, free of direct competition from arch-rival Novartis. The European Commission has approved Tecartus (brexucabtagene autoleucel) for adults aged 26 and over with relapsed or refractory B-cell precursor ALL, a patient population not covered by the label for Novartis’ CD19 CAR-T Kymriah (tisagenlecleucel), which covers paediatric and youn

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Prehistoric skeleton reveals oldest surgical amputation — in a hunter-gatherer society 31,000 years ago

STAT

The amputation happened when the individual was perhaps 12 years old, the skeleton indicates. Gone is the lower portion of the left leg. And somehow, the individual survived the surgical procedure — a remarkable feat given that it happened some 31,000 years ago. The skeleton, discovered in a cave on Borneo, in what is now Indonesia, appears to be evidence of the oldest known surgical amputation — 24,000 years earlier than that of a farmer in France, who had his left arm cut off an

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Want products with clean ingredients? There’s an app for that

Drug Store News

In theory, everyone wants to use “better for you” products, but whether the average consumer is willing to put the time and energy into finding those products can be the deciding factor.

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Roche pays $250 million to acquire Good Therapeutics and its preclinical cancer therapy

STAT

Good Therapeutics, a private company that raised just $30 million in venture financing since its 2016 foundation, said Wednesday it had signed a deal to sell itself to Roche for $250 million without ever running a clinical trial. The deal provides a roughly eight-fold return for Good’s investors, which included Codon Capital and RiverVest Venture Partners.

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Hy-Vee kicks off events to celebrate Family Meals Month, Hispanic Heritage Month

Drug Store News

Throughout September, Hy-Vee, along with its employees and partners are helping families come together during mealtime by providing resources and support to make mealtime easier.

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Age at Time of Type 2 Diabetes or Hypertension Diagnosis Linked to Glaucoma Risk

Drug Topics

Timing of type 2 diabetes or hypertension diagnosis may impact the risk of primary open-angle glaucoma.

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Evolving real-time dissolution prediction and product release

European Pharmaceutical Review

Researchers have developed a deterministic permeation model (DPM) that predicts the in vitro release profile of an active pharmaceutical ingredient (API) embedded in hydroxypropyl-methylcellulose (HPMC) matrix tablets. The model, based on Raman spectra, has the potential to process in real-time data yielded by process analytical technology (PAT) sensors, which could allow it to be utilised for real-time release testing (RTRt).

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Walmart, UnitedHealth Group partner on health services

Drug Store News

???????Select Walmart Health locations will help improve health outcomes for people by advancing value-based care, powered by Optum clinical capabilities.

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Study: Incubation Period of COVID-19 Strains Decrease Over Time

Pharmacy Times

Researchers suggest that understanding the incubation period of COVID-19 and its individual strains could determine the isolation period.

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Lannett completes clinical trial subject dosing of biosimilar insulin glargine

Drug Store News

Lannett anticipates launching biosimilar insulin glargine in the first half of 2024.

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FDA Approves Stimufend, Biosimilar for Pegfilgrastim-fpgk

Pharmacy Times

The biosimilar is expected to be launched as a prefilled syringe in early 2023.

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