Fri.Jan 20, 2023

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Pharmacy Focus - Big Picture for Health-System Pharmacies

Pharmacy Times

Carina Dolan, PharmD, BCOP, senior director for Clinical Oncology and Pharmaceutical Outcomes at Vizient Inc, discusses the highlights and big picture moving forward for hospitals and health-system pharmacies.

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FDA Grants Priority Review Designation to OPNT003 Nasal Nalmefene for Opioid Overdose

Drug Topics

The PDUFA date has been set for May 22, 2023.

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Trending Sources

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Study Shows That Breast Milk of Those Vaccinated Against COVID-19 Protects Infants

Pharmacy Times

Antibodies help neutralize the virus, though the levels decrease at the 6-month mark, data indicate.

Vaccines 167
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Zanubrutinib Approved in First-line or Relapsed/Refractory CLL/SL

Drug Topics

The approval makes zanubrutinib available to all patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) whether they are newly diagnosed or previously treated.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Cancer Survivor: ‘I Wish I Could Have Spoken to a Pharmacist,’ Received More Pain Management Support

Pharmacy Times

Sarah McDonald, cancer survivor and author of The Cancer Channel, discusses her experience battling 2 different unrelated cancers and the value oncology pharmacists could have provided with a greater presence on her care team.

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Biologics Provide Great Results for Psoriasis, but for a Price

Drug Topics

Highly effective medications for severe disease are expensive and administered invasively, while the development of treatments for milder disease has lagged, a new review on psoriasis clinical trials concludes.

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More Trending

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Opinion: The WHO’s new pandemic treaty is good for the world — and the U.S.

STAT

In December, delegates from more than 180 countries met in Switzerland to discuss the International Treaty for Pandemic Prevention, Preparedness, and Response, which had initially been proposed in December 2021. Support for it gained traction as the Covid-19 pandemic highlighted concerns about global vaccine inequity, genomic data-sharing, and more.

Vaccines 113
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FDA Grants Accelerated Approval to Tucatinib Combination for Patients with HER2-Positive Metastatic Colorectal Cancer

Pharmacy Times

This is the first indication for tucatinib that extends beyond the treatment of advanced unresectable or metastatic HER2-positive breast cancer.

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Buprenorphine deaths did not increase despite wider access during pandemic, study shows

STAT

The onset of the Covid-19 pandemic led to a sea change in addiction medicine — in particular, increased access to buprenorphine , a drug commonly used to treat opioid use disorder. Now, new data show that despite the medication’s wider availability, deaths involving buprenorphine still constitute a small fraction of overall drug mortality.

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Dollar General pilots mobile clinics as it targets a bigger presence in healthcare

Fierce Healthcare

Dollar General pilots mobile clinics as it targets a bigger presence in healthcare hlandi Fri, 01/20/2023 - 18:25

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Pharmacists Play Key Role in Encouraging COVID-19 Booster Uptake

Pharmacy Times

Educating patients, posting on social media, and countering misinformation are critical strategies.

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Study: Pharmacists can start patients on road to recovery from opioid-use disorder

Drug Store News

​​​​​​​A study in the New England Journal of Medicine showed that pharmacies can offer a safe and accessible treatment starting point for patients with opioid-use disorder and keep them better engaged.

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Employers should carefully weigh benefits of high-deductible health plans: study

Fierce Healthcare

Employers should carefully weigh benefits of high-deductible health plans: study fdiamond Fri, 01/20/2023 - 07:19

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Opinion: Even with lawsuits and copay caps, will insulin ever be affordable?

STAT

In an attempt to tackle the root causes of inflated insulin prices, the state of California filed a lawsuit last week accusing drug manufacturers and pharmacy benefit managers of artificially and illegally jacking up the price of insulin. The sausage-making of how insulin is priced is not for the faint of heart. It’s a complex tangle of drug manufacturers who’ve been resisting generics , health insurance companies trying to keep up impressive profits , plus the wholesalers who dist

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Iterative Health, Gastro Health partner over AI-enabled GI care and precision medicine R&D

Fierce Healthcare

Iterative Health, Gastro Health partner over AI-enabled GI care and precision medicine R&D aburky Fri, 01/20/2023 - 13:55

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Novel PET Radiotracer Reduces False-Positive Tumors After COVID-19 Vaccination

Pharmacy Times

18F-FDG PET/CT detects approximately 73% of tumor lesions, while 68Ga-FAPI finds approximately 94%.

Vaccines 132
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New Blues network spinout Lucet aims to simplify mental health benefits for payers

Fierce Healthcare

New Blues network spinout Lucet aims to simplify mental health benefits for payers pminemyer Fri, 01/20/2023 - 15:28

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Multiple Myeloma Therapy Often Causes Cardiovascular Complications

Pharmacy Times

Many patients have baseline risk factors present at diagnosis because of older age and disease-related elements.

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JPM23: Pfizer, Moderna and more look to combine COVID and flu vaccine markets

Fierce Pharma

JPM23: Pfizer, Moderna and more look to combine COVID and flu vaccine markets zbecker Fri, 01/20/2023 - 14:48

Vaccines 129
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STAT+: FTC wants ‘pharma bro’ Martin Shkreli held in contempt for violating lifelong ban on working in pharma

STAT

The U.S. Federal Trade Commission asked a federal judge to hold “pharma bro” Martin Shkreli in contempt for failing to provide the agency with information needed to determine whether he is violating an order that permanently banned him from working in the pharmaceutical industry. In a motion filed federal court in New York, the FTC and seven state regulators argued that Shkreli has failed to comply with their requests to provide documents and sit for an interview as part of their i

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Moderna takes aim at global expansion plans with manufacturing ramp-up

Pharmaceutical Technology

This week, at the World Economic Forum Annual Meeting, Moderna CEO Stéphane Bancel, said the company plans to build on its exponential growth through the pandemic by expanding its operations globally over the next few years. In 2020, Moderna made a net loss of $747 million while its investigational mRNA vaccines were under development. However, during the Covid-19 pandemic, the US-based biotech rose to prominence as it was one of the first companies to develop Covid-19 vaccines with its mRNA tec

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5 vitamins for smokers

The Checkup by Singlecare

Cigarette smoking is a public health problem that’s responsible for preventable chronic diseases and premature death. Many of the diseases are common knowledge from damaging lungs (causing asthma and pneumonia) or cellular changes leading to lung cancers; others include cardiovascular injury causing heart attacks and heart failure. But, some effects are less well known, like how cigarette smoking depletes vitamins in your body.

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Is mesothelin a key to tackling solid tumors? Some biotech companies are betting that it is

STAT

On Target is a recurring feature from STAT that dives deep into the most promising drug targets in oncology. This column is adapted from a new STAT report , “Targeting cancer: the new frontier of immunotherapy and precision oncology.” Scientists working to produce immunotherapies for solid tumor cancers have spent decades searching for biological targets that can help them distinguish between healthy cells and cancerous ones.

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What are authorized generics?

The Checkup by Singlecare

Chances are, you’ve taken a generic or authorized generic medication, and for good reason—according to the U.S. Food and Drug Administration (FDA), generic medications cost 80%-85% less than brand-name drugs. An estimated 90% of prescriptions filled in the United States are for commonly prescribed generic drugs. Examples include lisinopril for high blood pressure , levothyroxine for hypothyroidism , atorvastatin for high cholesterol , Type 2 diabetes medications like metformin , and others.

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STAT+: Pharmalittle: FDA rejects Lilly application for Alzheimer’s drug; Sanofi offers a warranty for a medicine

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is still in the works. For now, we expect to engage in our usual ritual of promenading with the official mascot, take a drive in the countryside with the radio turned up, and hold another listening party with Mrs.

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Dr. Lauren F. Lyles-Stolz joins NACDS to focus on reimbursement, innovation and advocacy

Drug Store News

Last year, Dr. Lauren F. Lyles-Stolz, PharmD joined the staff of the National Association of Chain Drug Stores as senior director of reimbursement, innovation and advocacy.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.   That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Retailers remove online-only purchase limits of OTC pediatric fever-reducing products

Drug Store News

Walgreens and Rite Aid have removed online purchase limits of OTC pediatric fever reducing products, while CVS currently has a two product limit on all children’s pain relief products at all locations and online.

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Martin Shkreli runs afoul of FTC for potentially skirting lifetime pharmaceutical industry ban

Fierce Pharma

Martin Shkreli runs afoul of FTC for potentially skirting lifetime pharmaceutical industry ban fkansteiner Fri, 01/20/2023 - 15:34

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Study: Black, Hispanic Individuals With Epilepsy Are Less Likely to be Prescribed Newer Drugs

Pharmacy Times

Inequities were also apparent between those who saw and did not see neurologists, analysis shows.

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Intas Pharmaceuticals under FDA scrutiny after oversight in GMP documents

Pharmafile

India-based manufacturer Intas Pharmaceuticals has been issued a Form 483 by the FDA after three investigators found a “cascade of failure” in a site inspection carried out at their manufacturing facility in Pharmez Special Economic Zone (SEZ) between late November and early December 2022.

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Kroger boosts associate productivity with Google Cloud, Deloitte partnership

Drug Store News

Kroger has teamed with Google Cloud and Deloitte on cloud technologies to increase associate productivity across the grocer’s nearly 2,800 stores nationwide.

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268K people who died from COVID-19 in first 2 years of pandemic not included in official tally: study

Fierce Healthcare

268K people who died from COVID-19 in first 2 years of pandemic not included in official tally: study fdiamond Fri, 01/20/2023 - 14:35

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Walgreens to pay West Virginia $83M for alleged role in opioid crisis

Drug Store News

The settlement with Walgreens brings the total West Virginia amount brought in from opioid litigation to more than $950 million.

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