Mon.Nov 14, 2022

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Current and Future Treatments for Hidradenitis Suppurativa

Drug Topics

Hidradenitis suppurativa is a chronic inflammatory skin condition that presents with painful, deep, and inflamed lesions found in flexural, apocrine gland-bearing sites.

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Higher Incidence of Myocarditis, Pericarditis Found After COVID-19 Vaccination

Pharmacy Times

Despite evidence of a higher risk of myocarditis or pericarditis with COVID-19 vaccination, immunization should still be recommended because the benefits likely outweigh the harms, study shows.

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Severe Asthma Clinical Outcomes Worsen After Stopping or Changing Biologics

Drug Topics

Findings from research presented at the American College of Chest Physicians suggest the importance of selecting the right biologic from the start.

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Early cell therapy successes start to turn the tide in lupus

Pharmaceutical Technology

In a field dominated by antibodies and small molecules, two cell-therapy based approaches have come under the spotlight for showing early signs of efficacy in treating lupus. In September, a group from Friedrich Alexander University Erlangen-Nuremberg reported that five patients with lupus achieved remission after an infusion of autologous chimeric antigen receptor (CAR)-T cells led to a deep depletion of B cells.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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The Implications of Opioid Use in Treating Cancer-Related Pain

Drug Topics

As the main course of treatment for cancer-related pain, the use of opioids comes with a number of issues for both patients and prescribers.

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Study Indicates Need for Non-invasive Testing for Hypertension During Post Hepatitis C Care

Pharmacy Times

Direct-acting antivirals have high efficacy for hepatitis C, however, patients with advanced liver scarring are at risk for the development of secondary diseases.

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Research Continues Evaluating Belantamab Mafodotin in Relapsed/Refractory Multiple Myeloma

Pharmacy Times

Belantamab mafodotin-blmf is a first-in-class, anti-B-cell maturation antigen therapy indicated for adults with relapsed or refractory multiple myeloma who have received at least 4 prior therapies.

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Time To First Prescription Fill at Health System, External Pharmacies Reviewed

Drug Topics

Timing of treatment initiation is crucial for patients with cancer.

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Case Study: The Pharmacist’s Role in Atopic Dermatitis Treatment

Pharmacy Times

The goals of therapy for atopic dermatitis include reducing symptoms of pruritis and dermatitis with disease control and prevention of flares.

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Dupixent nears EU approval for rare skin disease prurigo nodularis

pharmaphorum

Sanofi and Regeneron’s Dupixent is on track to become the first targeted drug in the EU to be approved for prurigo nodularis (PN), a rare and highly debilitating skin disease. The EMA’s human medicines committee (CHMP) has recommended IL-4 and IL-13 inhibitor Dupixent (dupilumab) to treat adults with moderate to severe PN, a disease which causes hard lumps to form on the skin that are so itchy they can lead patients to scratch themselves to the point of bleeding or pain.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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What you need to know about the amoxicillin shortage

The Checkup by Singlecare

Just as winter looms and everyone heads inside to cough, sneeze, and spread germs, a shortage of a popular antibiotic has developed. The U.S. Food and Drug Administration (FDA) has assigned “currently in shortage” status to oral powder for suspension amoxicillin. In fact, as of Oct. 28, the FDA listed 23 amoxicillin products on its current drug shortages page due to increased demand for the drug. .

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It’s time get real with healthcare’s commitment to net zero

pharmaphorum

Every fraction of a degree matters. COP27 is in full swing and world leaders are contending with the fact that we will likely not meet the Paris Agreement’s 1.5°C target. The reality is that we will need to focus on limiting a temperature rise wherever possible and that every fraction of a degree has a real and major consequence on our global environment.

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Brains of Black Americans age faster, study finds, with racial stressors a likely factor

STAT

The brains of Black adults in the U.S. age more quickly than those of white and Hispanic adults, showing features linked to Alzheimer’s disease and other dementias as early as mid-life, according to a new study. The study , published Monday in JAMA Neurology, analyzed the MRI scans of nearly 1,500 participants from two racially and ethnically diverse cohorts.

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Pharmacy Students Can Improve Gender Equity in Clinical Research

Pharmacy Times

Pharmacists can provide their knowledge to female patients but also ensure women are adequately represented in research.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Amazon debuts virtual health service

Drug Store News

Amazon Clinic will operate in 32 states and provide virtual care for more than 20 common health conditions, such as allergies, acne and hair loss.

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STAT+: Boom and bust: Whose biotech VC assets have grown and shrunk the most?

STAT

Money has gushed into the biotech industry over the last couple of years, as the pandemic brought the industry onto center stage. At the same time, tech investors have rushed into the arena. Who has benefited the most?

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CVS pharmacists to prescribe COVID-19 antiviral treatments nationwide

Drug Store News

CVS pharmacists can assess eligible COVID-19 positive patients and prescribe oral antiviral medication at most locations.

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Challenges, Opportunities Mark Health Care Landscape in 2022

Pharmacy Times

Burnout, drug and technician shortages, home care, remote work, and telehealth continue to trend.

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STAT+: Google travels far from Silicon Valley to test the power of search tools in health care

STAT

Mile Bluff Medical Center is a long way from Silicon Valley. The 40-bed hospital is situated in a central Wisconsin city of 4,400 people, where caregivers are about as likely to encounter a moose as a machine learning engineer. That is, until now.

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6 best exercises for ADHD

The Checkup by Singlecare

ADHD, or attention deficit hyperactivity disorder, is a neurological condition that interferes with many typical functions of the brain , particularly those related to planning and organization, impulsivity, focus and attention, and executive functioning. Like most other mental health conditions, ADHD is best managed with a combination of strategies that consider an individual’s overall health, daily routine, social and emotional needs, and even their personality.

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Moderna data suggest new Covid booster is more effective against Omicron variants

STAT

New data indicate Moderna’s Covid bivalent booster may be more effective against currently circulating Omicron variants of the virus than its original vaccine, the company said Monday. Like data released by Pfizer and BioNTech regarding their Covid vaccine , the new data involves lab measurements of antibodies and their ability to neutralize the SARS-CoV-2 virus, not data on how well the vaccines prevent cases of symptomatic illness or severe disease.

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FDA grants accelerated approval for ImmunoGen’s ovarian cancer ADC

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted accelerated approval for ImmunoGen’s Elahere (mirvetuximab soravtansine-gynx) to treat adults with folate receptor alpha (FR?)-positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer. The antibody-drug conjugate (ADC) treatment is indicated for such patients who have previously received one to three systemic therapy regimens, irrespective of the usage of Avastin priorly.

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Why the IRA will drive up the country’s drug bill — not lower it

PharmaVoice

On the surface, the Inflation Reduction Act is designed to lower drug prices, but its impact on innovation incentives could produce a landscape of new medicines that are costlier for patients.

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Vaccine Confidence Decreased Significantly During Pandemic

Drug Topics

Confidence in vaccines is lower post-pandemic across all demographic groups.

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Low-dose aspirin use associated with higher risk of serious falls in elderly

Hospital Pharmacy Europe

An RCT has found that low-dose aspirin use failed to reduce fracture risk but was associated with higher risk of serious falls in the elderly. Daily low-dose aspirin (100 mg) use in healthy elderly patients failed to reduce the risk of fractures but increased the risk of a serious fall according to the findings of a randomised, placebo-controlled trial by Australian researchers.

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Transparency influences shopper’s beauty, personal care purchases

Drug Store News

NielsenIQ’s VP of Total Wellness discusses the latest trends influencing how shoppers are searching for, engaging with and purchasing personal care and beauty products.

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STAT+: She was a celebrated oncologist. Why did she hide her breast cancer until it was too late?

STAT

When Barrett Rollins walked into the bathroom of his Beacon Hill home, he was stunned to find his wife lying on the uneven tile floor covered in blood. Rollins and his wife, Jane Weeks, were physicians and researchers at Dana-Farber Cancer Institute and lived steps from some of the world’s best hospitals. But Weeks didn’t want medical help.

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FDA Accepts New Drug Application for Zilucoplan for Generalized Myasthenia Gravis

Pharmacy Times

Zilucoplan is a subcutaneous, self-administered peptide inhibitor of complement component 5.

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University of California academic workers go out on strike to demand higher wages

STAT

Any other Monday morning, Josh Mesfin would have been in the lab, performing surgery on rats and devising new ways to help them heal from heart attacks — with the hope of one day using those same tools to help people. But the fourth-year UC San Diego bioengineering graduate student spent the day chanting and marching alongside fellow academic workers who launched a strike at 10 University of California campuses on Monday, decrying low wages that Mesfin says make instant ramen a dietary st

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Prescription drug sales through HDA healthcare distributors remained strong in 2021

Drug Store News

Prescription drugs make up the majority (98%) of distributors' sales, split among sales of brand-name drugs (55.3%), branded specialty (33.7%), generic drugs (7.8%), generic specialty (.6%) and biosimilar products (.7%).

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STAT+: Immunogen wins FDA approval for targeted medicine to treat advanced ovarian cancer

STAT

The Food and Drug Administration on Monday approved a new treatment for patients with advanced ovarian cancer — an antibody that delivers a targeted dose of chemotherapy directly to cancer cells. The new drug, called Elahere, was developed by Immunogen, a biotech company based in Waltham, Mass. It’s the first new treatment option for advanced ovarian cancer to reach the U.S. market in more than seven years, and the first approval of a wholly owned medicine in Immunogen’s 41-

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CHPA Educational Foundation pilots OTC Pain Reliever Selection at Dollar General

Drug Store News

Featuring signage at nearly 19,000 Dollar General stores in 47 states, the campaign reflects the Foundation’s partnership with Haleon, J&J and Perrigo.

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STAT+: Maven raises $90 million for women’s and family health amid a funding drought

STAT

Women’s and family health tech startup Maven Clinic announced Monday it has raised $90 million in a Series E funding round led by General Catalyst, raising the company’s valuation to $1.35 billion. The funding, which brought Maven’s total funding to $300 million, comes at a time when investment into health tech companies has slowed, with patients returning to their doctors’ offices and employers considering scaling back their virtual care benefits amid an economic dow

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EMA human medicines committee (CHMP) highlights, November 2022

European Pharmaceutical Review

Four medicines recommended for approval in the European Medicines Agency (EMA)’s Committee for Medicinal Products for Human Use (CHMP)’s latest meeting included a biosimilar for osteoporosis and a novel COVID-19 vaccine. VidPrevtyn Beta, recommended as a new recombinant, adjuvanted booster COVID-19 vaccine in adults previously vaccinated with an mRNA or adenoviral vector COVID-19 vaccine, is the seventh COVID-19 vaccine recommended for approval in the European Union (EU).