Fri.Mar 10, 2023

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PBM Formulary Exclusions List Reaches All-Time High

Drug Topics

Critics of PBM's say that the high number of exclusions narrows patient options and make medications financially inaccessible.

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STAT+: SVB, biotech’s bank of choice, just failed. It could have ripple effects

STAT

Silicon Valley Bank, which does business with roughly half of the nation’s tech and biotech companies, failed on Friday. Now, as federal regulators step in to clean up SVB’s mess, biotech startups are left wondering: What happens to their money, and who’s going to finance the industry? On Friday morning, the Federal Deposit Insurance Corporation took control of SVB and is presiding over a sale of the firm’s assets to cover clients’ deposits.

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Trending Sources

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Show Me the Way: Technician-Led Pharmacy Services

Drug Topics

Pharmacy technicians can play an important role in leadership at the pharmacy.

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New NHS cell and gene therapy centre opens

European Pharmaceutical Review

Today marks the opening the NHS Blood and Transplant (NHSBT)’s new Clinical Biotechnology Centre (CBC) in Bristol. The state-of-the-art facility was part-funded by a £9.43 million Government grant and is designed to expand the UK’s ability to manufacture new gene and cell therapies. The CBC will help the UK grow its cell and gene therapy industry in a rapidly growing international market.” “The CBC will help the UK grow its cell and gene therapy industry in a rapidly growing international

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Opinion: Ranked to fail: Does gatekeeping affect diversity in The Match?

STAT

For graduating medical students hoping to secure a residency training position — and that’s virtually all of them — Match Day is the most anticipated day of the year. The Match is the culmination of medical school, application preparation, interviews, and recruitment events. It’s like a traditional job search but without the room for negotiation since it is based on an algorithm that announces job placement once a year, on the third Friday of March, for all participat

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New facility boosts UK’s cell and gene therapy manufacturing capacity

Pharmaceutical Technology

On 10 March, the National Health Service Blood and Transplant (NHSBT) opened a new Clinical Biotechnology Centre (CBC) with the aim of improving the UK’s ability to develop and manufacture cell and gene therapies. A £9.3 million ($11 million) grant is being used to build the facility in Bristol where therapies for currently incurable diseases, such as some forms of cancer, sickle cell disease, and cystic fibrosis can be manufactured.

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US FDA approves Pfizer’s migraine nasal spray Zavzpret

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted approval for Pfizer ’s Zavzpret (zavegepant) for the acute treatment of migraine in adult patients with or without aura. Zavzpret is claimed to be the first and only calcitonin gene-related peptide (CGRP) receptor antagonist nasal spray approved to treat migraine. It is a third-generation, selective and structurally unique, small molecule CGRP receptor antagonist and is currently under clinical development with oral and intranasal formulation

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Does caffeine raise your blood pressure?

The Checkup by Singlecare

If you find yourself reaching for a cup of coffee every morning or swigging an energy drink each afternoon, you’re not alone. Caffeine is the world’s most-consumed drug—found in the leaves and fruits of some plants, and a key ingredient in caffeinated beverages like coffee, energy drinks, soft drinks, and black or green tea. It’s also found in energy snacks and some non-prescription drugs.

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Antioxidant and anti-inflammatory therapy worsens cognitive and psychological outcomes following sepsis

Hospital Pharmacy Europe

Antioxidant and anti-inflammatory therapy given to sepsis survivors led to worse cognitive and psychological scores after 6 months The provision of antioxidant and anti-inflammatory treatment for sepsis survivors gave rise to lower cognitive and psychological scores compared to placebo after 6 months, according to a randomised trial by the VICTAS investigators.

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Sunscreen usage for anti-aging purposes increases

Drug Store News

Sunscreen and skin protection products saw a surge in retail sales from 2021 to 2022, and the market is expected to grow by 7% in the next year, according to a new survey from Mintel.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Controversial Preterm Birth Prevention Drug To Be Removed From Market

Drug Topics

The drug, called Makena, was intended to stop premature births, but has not been effective in its goal, says the FDA.

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ImageMover, QuidelOrtho simplify test-to-treat process for pharmacies

Drug Store News

An integrated solution combines QuidelOrtho's Sofia 2 fluorescent immunoassay analyzer, an automated small benchtop system, with Workflow Services to create a one-stop solution for pharmacists, the companies said.

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Biotech centre focusing on gene therapies opens in Bristol, UK

Pharmafile

A new state-of-the-art facility named the Clinical Biotechnology Centre (CBC) is opening in Bristol, UK. It cost approximately £10m to build, funded by the UK Government. CBC is aiming to support the UK’s cell and gene therapy (CGT) industry, from manufacturing DNA plasmids and viral vectors which are used to create gene and genetically modified cell therapies, to supporting early phase clinical trials and preclinical work.

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Neoadjuvant pembrolizumab improves event-free survival compared to adjuvant therapy in advanced resectable melanoma

Hospital Pharmacy Europe

Neoadjuvant pembrolizumab in patients with advanced melanoma provides superior event-free survival compared to adjuvant therapy alone Using neoadjuvant pembrolizumab therapy for patients with stage III or IV resectable melanoma gives greater 2-year event-free survival than adjuvant therapy according to the findings of randomised, phase2 trial by US researchers.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Walgreens Boots Alliance annual ESG virtual event convenes industry leaders for report launch

Drug Store News

Joined by EY, Reckitt and Neurodiversity in the Workplace, discussions covered health equity, sustainability, disability hiring and supply chain resiliency.

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STAT+: Medicare will take R&D costs, effectiveness into account when it negotiates drug prices. But studies show that doesn’t affect prices

STAT

By law, Medicare will have to take a medication’s efficacy and its research and development costs into account when it starts to negotiate drug prices — but recent research shows pharma companies ignore those factors when they pick prices for their products. Two recent studies aimed to quantify how much R&D costs impact a drug’s price, and how much a drug’s effectiveness correlates with its price — factors that might, in theory, help justify a sizable price

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FDA calls expert hearing for Intercept’s high-profile NASH application for Ocaliva

Fierce Pharma

FDA calls expert hearing for Intercept’s high-profile NASH application for Ocaliva aliu Fri, 03/10/2023 - 10:49

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STAT+: Several years later, AstraZeneca says its drug extends life for some early-stage lung cancers

STAT

Ever since the Food and Drug Administration approved osimertinib for some early-stage lung cancer patients to take after surgery, clinicians have debated whether the evidence suggested the drug was worth the cost. The initial results of the phase 3 trial testing the drug were “phenomenal,” said Sandeep Patel, a medical oncologist at the University of California, San Diego.

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Medicaid health plans try to protect members—and profits—during unwinding

Fierce Healthcare

Medicaid health plans try to protect members—and profits—during unwinding pminemyer Fri, 03/10/2023 - 13:44

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.   That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Feds shut down tech investor Silicon Valley Bank, major investor in health tech, biotech companies

Fierce Healthcare

Feds shut down tech investor Silicon Valley Bank, major investor in health tech, biotech companies fdiamond Fri, 03/10/2023 - 14:49

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Being KOL-Centric: More Meaningful Expert Engagement

PharmExec

Global medical affairs teams seek better support to manage relationships with key opinion leaders—and find that balance between patient needs, scientific objectives, and the interest areas of KOLs.

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These are the major challenges hospital executives expect to face this year

Fierce Healthcare

These are the major challenges hospital executives expect to face this year fdiamond Fri, 03/10/2023 - 15:47

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Goli Nutrition debuts Women’s PMS Relief Gummies

Drug Store News

To launch its new gummies, the brand is debuting a campaign that celebrates PMS through a musical approach.

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Industry Voices—Pharmacists play key role in advancing health equity, pharmacoequity

Fierce Healthcare

Industry Voices—Pharmacists play key role in advancing health equity, pharmacoequity pminemyer Fri, 03/10/2023 - 14:21

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Enhancing bioavailability in ocular drug delivery

European Pharmaceutical Review

A review by researchers on ocular drug delivery discussed strategies that could enhance ocular bioavailability. Currently, effective topical administration is challenging as the industry aims to prolong drug residence time and guarantee appropriate ocular permeation. Although many potent drugs are available to treat most ocular complaints, there are barriers such as tear film, corneal and conjunctival.

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Political headwinds grow against CMMI accelerated approval drug price model

Fierce Healthcare

Political headwinds grow against CMMI accelerated approval drug price model rking Fri, 03/10/2023 - 16:16

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HRG reviews 1,875 new items in 2022

Drug Store News

Within the top five categories in independent pharmacy, 564 new items were reviewed, with nearly 17% awarded Stars.

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New female-led, encrypted period tracker app Embody to launch this summer

Fierce Healthcare

New female-led, encrypted period tracker app Embody to launch this summer agliadkovskaya Fri, 03/10/2023 - 14:34

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Hostess sweetens breakfast with Donettes, Baby Bundts

Drug Store News

New launches from the brand include Donettes Old Fashioned Mini Donuts and Chocolate Drizzle Baby Bundts.

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Senators urge CMS to close 'loopholes' in payer price transparency rule

Fierce Healthcare

Senators urge CMS to close 'loopholes' in payer price transparency rule pminemyer Fri, 03/10/2023 - 16:12

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BJ’s Wholesale Club adds 5 new clubs, expands into Alabama

Drug Store News

The opening of the company's first club in Madison, Ala., expands the retailer's footprint to 20 states.

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News Roundup March 6-March 10

Drug Topics

Your weekly roundup of the latest news from Drug Topics®.

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Generative AI’s Breakthrough Potential in Pharma Marketing

PharmExec

How platforms like ChatGPT could transform engagement models.

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