Tue.Sep 20, 2022

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The dangers of expanding the TRIPS waiver

PhRMA

World Trade Organization (WTO) members, including the United States, are considering waiving commitments to honor certain intellectual property (IP) rights on COVID-19 treatments, following a harmful and unnecessary decision to do the same for COVID-19 vaccines. This is referred to as the TRIPS waiver.

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Distinguishing Egg-Based Vs Cell-Based Vaccines

Drug Topics

Distinctions between vaccine types are explored, as well as considerations such as egg-based allergies.

Vaccines 184
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Trending Sources

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Study: Medical Cannabis May Have Far-Reaching Benefits for Neurological Disorders

Pharmacy Times

Research suggests cannabis can improve quality of life for patients who suffer from pain and neurological disorders.

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Hope for lupus sufferers with Feinstein Institutes-led phase 2 trial

pharmaphorum

Findings from the litifilimab trial, undertaken by Northwell Health’s Division of Rheumatology and The Feinstein Institutes for Medical Research, have been published in the New England Journal of Medicine and show promise for those who have been diagnosed with systemic lupus erythematosus (SLE). Sponsored by Biogen Inc., data from the phase 2 LILAC (Part A) clinical trial published this month shows that the experimental lupus therapy could reduce disease activity in the joints of patients, globa

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Glaucoma Treatment Shows Positive Results in Phase 3 Trial

Pharmacy Times

Researchers will submit a new drug application to the FDA after a phase 3 trial found that iDose TR slow- and fast-release models met their primary endpoint in patients with glaucoma.

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Housing, Food Insecurity Can Be Caused By Medical Debt

Drug Topics

Hospitalization, disability, having private high-deductible, Medicare Advantage, or no coverage were risk factors associated with medical debt.

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Homeopathy: An easy pill to swallow for many Americans

Drug Store News

As more people seek out a multidimensional approach to health, interest in homeopathic medicine is on the rise.

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Ultra-Processed Foods Found to Increase Colorectal Cancer Risk in Men

Pharmacy Times

Study indicates that a diet high in ultra-processed food is more likely to increase the risk of colorectal cancer in men than it is women.

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Navigating Concerns Around Influenza Vaccination and Adverse Events

Drug Topics

Vaccination discussion continues with a focus on navigating patient concerns and potential adverse effects to vaccine administration.

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STAT+: Minimal compliance, or meaningful change? Epic faces a crossroads as new rules put pressure on health data sharing

STAT

In the business of selling record-keeping software to hospitals, Epic Systems is breaking away from the pack. The Wisconsin-based company’s contracts now account for nearly half the nation’s hospital beds, and in recent months it has jumped out to a commanding lead over No. 2 Oracle Cerner, taking away dozens of customers. More than 253 million Americans, or 77% of the population, are estimated to now have data in the company’s software.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Walmart Connect announces social media, livestream partnerships

Drug Store News

Walmart Connect announced several partnerships that will help create a diverse ecosystem to expand advertiser support, increase services and deliver access anywhere advertisers need it.

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A new study asks: Are we harming blood donors by taking blood from them?

STAT

One question has plagued the field of blood donation for as long as there have been transfusions: Are we harming blood donors by taking blood from them? Our iron stores are largely self-conserved: Our bodies recycle iron from old red blood cells to make new red blood cells. Iron that’s in use doesn’t tend to exit the body unless a person loses blood, whether through menstruation, bleeding from trauma, illness — or through donation.

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Modified paracetamol overdose protocol leads to reduction in hospital length of stay

Hospital Pharmacy Europe

An ED paracetamol overdose protocol with a treatment duration of only 12 hours significantly reduced the length of patient’s hospital stay. An emergency department (ED) paracetamol overdose protocol which has a treatment duration of 12 hours, significantly reduced the length of hospital stay in comparison the standard 21-hour protocol and could become more widely adopted according to the findings of a retrospective analysis by researchers based at the Emergency Department, University Hospi

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STAT+: New CRISPR startup, drawing big-name backers, seeks to fix diseases caused by large DNA errors

STAT

A new CRISPR startup — backed by some big names in venture capital — is planning to develop gene-editing treatments that can insert a genetic sequence of any length, at any location in the DNA strand, according to industry insiders and documents. The biotech is called Tome Biosciences, and it hopes to write the next chapter in genomic medicines.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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California Modifies End of Life Option Act

Pharmacy Times

Amendments reflecting more contemporary options could raise ethical questions for health care workers.

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Poxviruses, outbreaks, and Ebola: A Q&A with a retiring CDC expert on bad bugs

STAT

In the last week of August, one of the world’s foremost poxvirus experts retired from the Centers for Disease Control and Prevention. To outside eyes, the timing of Inger Damon’s departure could be seen as odd or unfortunate, given that after years of relative obscurity, poxviruses are at the center of the world’s infectious diseases radar, thanks to the ongoing monkeypox outbreak.

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Consolidation Forces Pharma to Rethink Commercial Strategies: Q&A with Beghou Consulting’s Rohit Gupta

PharmExec

Rohit Gupta is vice president of analytics strategy and transformation at Beghou Consulting - he works with biopharma leaders on all facets of drug commercialization, from market sizing strategies, to launch planning, to business analytics.

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Green HPLC method enables antipsychotic determination

European Pharmaceutical Review

In a recent paper, researchers demonstrated the comparability of a green high performance liquid chromatography (HPLC) for the determination and screening of typical antipsychotic drugs both in bulk and pharmaceutical formulation. Antipsychotics are used to treat a variety of serious mental disorders including schizophrenia and bipolar disorder, in which manic states may require management with multiple drugs.

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Study: Increased Diet of Fish, Fiber, Omega-3 Fatty Acids May Decrease Risk of Death in Adults with Type 2 Diabetes

Pharmacy Times

Adults with type 2 diabetes may benefit from eating more whole grains, fish, fiber, and omega-3 fatty acids in their diet, which could lower co-morbidities associated with death.

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Epic hits a crossroads, judge rules on UnitedHealth’s Change bid, & Meta faces health data pressure

STAT

You’re reading the web edition of STAT Health Tech, our guide to how tech is transforming the life sciences.  Sign up to get this newsletter  delivered in your inbox every Tuesday and Thursday.

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EMA approves biosimilar interchangeability in EU

European Pharmaceutical Review

The Heads of Medicines Agencies (HMA) and the European Medicines Agency (EMA) have announced that biosimilar medicines authorised in the European Union (EU) can now be interchanged with their reference medicine or an equivalent biosimilar product. Interchanging biosimilars is an acceptable practise already used by many Member States. However, the current lack of certainty whether interchangeability is acceptable EU-wide has prompted this decision.

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Contraceptive Access Negatively Impacted by COVID-19

Drug Topics

In a recent study, it was found that access to contraceptive services declined during the COVID-19 pandemic.

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Study: Mediterranean Diet Positively Associated with Cognitive Function

Pharmacy Times

Changing one’s diet could change brain health and study results suggest the Mediterranean diet could positively support cognitive function.

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Opinion: Preventive services can improve Americans’ health, but they are now on trial

STAT

Twelve years after the Affordable Care Act was enacted, it appears to be here to stay, fully integrated into the nation’s health care system, extending coverage to more than 30 million Americans and protecting coverage against pre-existing conditions. The Supreme Court has ruled three times that the law is constitutional, and neither political party seems interested in overhauling it.

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Patient Preferences for Newer Oral Therapies in Type 2 Diabetes Found in Survey

Drug Topics

A survey offers new insight into patient preferences related to newer oral therapies in type 2 diabetes.

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STAT+: UnitedHealth bid for Change Healthcare may proceed, judge rules

STAT

A federal judge on Monday shot down the U.S. Justice Department’s legal challenge to UnitedHealth Group’s $13 billion acquisition of the technology company Change Healthcare.  Judge Carl Nichols’ one-page order denying the government’s bid to stop the merger stipulated that UnitedHealth divest Change’s claims editing subsidiary, ClaimsXten, to TPG Capital.

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Zuranolone shows promise as episodic treatment for depression

European Pharmaceutical Review

New data supports the potential use of Biogen’s and Sage Therapeutics’ zuranolone as a potential episodic treatment for people with major depressive disorder (MDD). Zuranolone is an investigational oral 14-day treatment under clinical development for adult patients with MDD and postpartum depression. In the ongoing open-label, longitudinal SHORELINE Study in MDD, the median time to the first repeat treatment course for those patients who responded to the initial 14-day treatment course was

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Study: Racial Disparities in Outcome of Neoadjuvant Endocrine Therapy for HR-Positive Breast Cancer Patients

Pharmacy Times

Black women are suggested to be diagnosed with stage 3 HR-positive breast cancer and receive longer neoadjuvant endocrine therapy more often than White women.

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Perricone MD expands acne relief line with clearing treatment

Drug Store News

The Maximum Strength Clearing Treatment is formulated with salicylic acid in a sustained delivery system for less irritation, the beauty brand said.

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Opinion: Hospital financing in black and white

STAT

During our training as doctors, we have rotated through safety-net hospitals, elite academic medical centers, and private clinics. The resources for patient care and comfort were sumptuous in some facilities, spartan in others. The differences were often night and day or, as we quantified in a later analysis, black and white: we cared for far more white patients at highly resourced facilities and many more Black patients and other patients of color at those with fewer resources.

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Hi-Chew releases better-for-you Fi-Being candies

Drug Store News

Fi-Being, available in passion fruit and elderberry flavors, contains 11 g of dietary fiber, 4 g of sugar and 0 g of sugar alcohol, the brand said.

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STAT+: Pharmalittle: Haleon argues it’s not liable for any Zantac claims; FDA steps up surprise inspections in India

STAT

Top of the morning to you, and a fine one it is. Crystal clear blue skies and deliciously cool breezes are enveloping the Pharmalot campus today, making for a lovely start. Our official mascot is bounding about the grounds in search of critters and we are happily brewing a cup of stimulation — our choice is bourbon pecan. As always, please feel free to join us.

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Amazon to bring low carbon electrofuels to its trucking fleet

Drug Store News

???????An agreement with Infinium will help Amazon reduce carbon emissions for roughly 5 million miles of travel per year, the company said.

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First bispecific antibody approved in EU to combat leading causes of vision loss

European Pharmaceutical Review

The European Commission has approved Roche’s Vabysmo ® (faricimab) for the treatment of neovascular or ‘wet’ age-related macular degeneration (nAMD) and visual impairment due to diabetic macular oedema (DME) – two of the leading causes of vision loss worldwide. “Many people with nAMD and DME struggle to keep up with the monthly eye injections and physician visits, often associated with current standards of care, and unfortunately their vision may suffer as a result of undertreatment,” explained