Fri.Jul 22, 2022

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Review Finds No Link Between Serotonin Levels, Chemical Imbalance and Depression

Pharmacy Times

A review of decades of research concluded that there is no evidence of an association between serotonin levels and depression, calling the function of antidepressants into question.

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Pfizer, Flynn fined £70m in resurrected epilepsy drug pricing probe

pharmaphorum

Drugmakers Pfizer and Flynn Pharma have been fined £70 million ($84 million) by the UK Competition and Markets Authority (CMA) for overcharging the NHS for a widely-used epilepsy drug. The CMA delivered a preliminary judgment in the case last year which concluded that Pfizer and Flynn abused a dominant position in phenytoin sodium capsules, causing NHS spending on the drug to balloon from around £2 million a year in 2012 to £50 million the following year.

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Trending Sources

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Daily Medication Pearl: Privigen Immune Globulin Intravenous (Human)

Pharmacy Times

Privigen is indicated for the treatment of primary humoral immunodeficiency, chronic immune thrombocytopenic purpura in patients 15 years of age and older, chronic inflammatory demyelinating polyneuropathy in adults.

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Amazon ratchets up its health ambitions, buying US primary care group

pharmaphorum

Amazon has accelerated its expansion into the healthcare sector with an all-cash deal to acquire One Medical, a US group that provides virtual and in-person primary care services using a subscription fee model. Amazon is buying One Medical for $18 per share, valuing the company at around $3.9 billion and making it one of the online retail giant’s largest-ever acquisitions – and by far its biggest within the health category.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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The Ability to Pay for Performance, Outcomes for Patients Past DIR

Pharmacy Times

Pharmacies need to kind of move beyond those models that are more punitive and look for true pharmacy-based measures and the ability to pay for performance and outcomes for patients.

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ASRS conference reveals hopeful outcomes for gene therapy RGX-314 in retinal diseases

Pharmaceutical Technology

Pipeline therapies within the diabetic macular oedema (DME) space have recently gathered interest following the American Society of Retina Specialists (ASRS) Annual Meeting, which took place on 13–16 July. The spotlight was placed on many up-and-coming pharmacotherapies for retinal diseases, one of which was AbbVie’s/Regenxbio’s gene therapy RGX-314.

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Largest-Ever Industry Report Reveals Video Meetings 3x More Effective and Companies Using Them Most Gain Advantage

PharmExec

Data from over 130 million quarterly HCP-field interactions across 80% of global biotech and pharma companies unveiled in Veeva Pulse Field Trends Report - industrywide data shows frequent use of key digital channels is vital for effective HCP engagement.

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An Overview of Specialty Pharmacy in Health-Systems

Pharmacy Times

The evolving landscape of specialty pharmacy growth represents the impact it may have on the operations of the health-system moving forward.

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The new European Unitary Patent system – What you need to know

pharmaphorum

The proposed European unitary patent and unified patent court represents one of the largest changes to the European patent system in a generation. It will usher in a new European patent right (the unitary patent) which will have unitary effect across participating member states. A new court system (the unified patent court or UPC) will also be established to handle litigation not only of the new unitary patents, but also of European patents under the current system that are validated nationally

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PrEP Delivery Remains Low Among Those With Opioid/Stimulant Use Disorder

Pharmacy Times

Preexposure prophylaxis should be consistently offered alongside HIV prevention services and treatment for substance abuse, investigators say.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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EC approves amendment of Valneva’s Covid-19 vaccines purchase deal

Pharmaceutical Technology

The European Commission (EC) has approved an advance purchase agreement (APA) amendment for Valneva’s inactivated whole-virus Covid-19 vaccine, VLA2001. The latest move follows remediation discussions based on the notice sent to the company regarding the termination of the initial APA for purchasing vaccine doses this year and the optional doses for next year.

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Study Finds Non-Opioid Pain Prescriptions Increased Following 2016 CDC Guideline

Pharmacy Times

The increase in prescriptions for non-opioid pain medications coincided with a significant drop in opioid prescribing over the same period.

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ARS Pharmaceuticals to merge with Silverback Therapeutics

Pharmaceutical Technology

ARS Pharmaceuticals has signed a definitive agreement to merge with Silverback Therapeutics in an all-stock transaction. The combined company will operate under the name ARS Pharmaceuticals and be headquartered in San Diego, California, US, after the completion of the transaction. It will focus on the potential regulatory clearance and commercialisation of ARS’ investigational epinephrine nasal spray, neffy.

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Pharmacy Focus Episode 51: Combatting the Opioid Epidemic in the Emergency Medicine Space

Pharmacy Times

There are some great resources out there to help educate patients and healthcare providers to combat the epidemic, according to Dr. Deutsch.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Top tweets: Covid-19 headed towards seasonality – and more

Pharmaceutical Technology

Pharmaceutical Technology lists five of the top tweets on infectious diseases in Q2 2022 based on data from GlobalData’s Pharmaceuticals Influencer Platform. The top tweets are based on total engagements (likes and retweets) received on tweets from more than 188 infectious diseases experts tracked by GlobalData’s Pharmaceuticals Influencer platform during the second quarter (Q2) of 2022.

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Help Patients Use Inhalers Properly

Pharmacy Times

Choosing the appropriate device and using the correct technique are critical for drug delivery to the lungs.

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2nd Annual Next Generation Pharmaceutical Cleanrooms Conference

pharmaphorum

Sponsored by Ecolab, Elis Cleanroom, Innerspace, Microgenetics, Novatek. Co-Chaired by: Conor Murray, Chairman, Irish Cleanroom Society and Connor McMorrow, Aseptic Lead Cell Therapy, Takeda. Advances in Pharma 4.0 for an Improved, Efficient and Contaminant-Free Cleanroom. [link]. SAE Media Group are pleased to announce the 2nd Annual Next Generation Pharmaceutical Cleanroom Conference.

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Responding to Vaccine Reluctance Across Patient Populations

Pharmacy Times

Ed Cohen, PharmD, FAPhA, holds a panel discussion exploring pharmacist-provided immunizations, focusing on COVID-19–specific updates and recommendations.

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Report finds UK risks falling behind rivals in life sciences

pharmaphorum

A just-published report on the UK’s life sciences sector “ought to ring alarm bells across government,” according to the Association of the British Pharmaceutical Industry (SBPI). The Life Sciences Competitiveness Indicators report shows that spending on life sciences R&D was £2.7 billion in 2020 – accounting for 0.12% of GDP and ranked third among the top 15 industrialised nations, behind only the US and Japan.

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Vaccination Advocation Amid Misinformation

Pharmacy Times

Pharmacists discuss the impacts of inaccuracy on vaccine hesitancy and offer communication strategies for conversations with patients.

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Oncoustics raises $5.5m for ‘virtual biopsy’ AI platform

pharmaphorum

Digital health startup Oncoustics has raised $5.5 million in seed funding to develop an artificial intelligence-powered technology that will be used to spot and diagnose liver diseases from ultrasound images. The new company – based in Toronto and San Francisco – will use the new funding to accelerate the development of its lead software-as-a-medical device (SaMD) OnX, used to detect changes like scaring (fibrosis) and fatty build-up (steatosis) in chronic liver diseases.

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Knowing Personal Value is Key for Pharmacy Technicians to Advance Their Career

Pharmacy Times

Seeking personal fulfillment over money can help when assessing one’s value as a pharmacy technician.

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The Case for Market Access.Early and Often

PharmExec

Industry veteran Ken Abreu makes the case for approaching market access very early in the process, and elucidates why it's so important.

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Study Suggests Brentuximab Vedotin May Improve Overall Survival in Patients With Hodgkin Lymphoma

Pharmacy Times

Progression-free survival was longer with brentuximab vedotin and fewer patients with Hodgkin lymphoma in this group received subsequent therapy.

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When Will Payers Improve Coverage of Prescription Digital Therapeutics?

PharmExec

New MMIT research highlights payers’ continued hesitancy toward PDTs. Here’s what manufacturers need to know.

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Pivotal Trial Demonstrates Antitumor Activity With Tucatinib, Trastuzumab in Previously Treated HER2-Positive Metastatic Colorectal Cancer

Pharmacy Times

The results showed a 38.1% confirmed objective response rate among HER2-positive patients who received tucatinib in combination with trastuzumab.

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Biocair Develops Dedicated Team for Cell and Gene Therapy Logistics

Pharmaceutical Commerce

Company is developing a team of over 30 dedicated specialists to deliver 24-hour global support for CGT service users.

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Approval of Tapinarof Introduces New Class of Topical Treatments for Management of Plaque Psoriasis

Pharmacy Times

Tapinarof is a first-in-class topical steroid-free aryl hydrocarbon receptor antagonist intended to mitigate the symptoms of plaque psoriasis.

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NICE recommends Rhythm’s Imcivree to help treat obesity and control hunger

Pharma Times

The treatment has been developed for people aged six years and over will be available for use across the NHS

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AbbVie Files Migraine Prevention Drug Atogepant in European Union

Pharmacy Times

The submission is based on 2 pivotal phase 3 studies evaluating the drug in adult patients with chronic and episodic migraines.

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Making the Commercialization Process Worthwhile

Pharmaceutical Commerce

Tips for navigating the obstacles surrounding product launch.

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Daily OTC Pearl: Thera Tears

Pharmacy Times

Thera Tears helps with the symptoms of dry eyes.

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Vicebio targets development of novel vaccines

Pharma Times

Molecular clamp technology is a protein tag that stabilises a wide range of complex viral proteins

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SGLT2 Inhibitors Are Shown to Reduce HF Death and Hospitalization

Pharmacy Times

Empagliflozin also was associated with Improvement in quality of life and greater reduction in body weight.