Sat.Dec 10, 2022

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STAT+: Bone marrow transplant patients could be spared from ‘bland’ diet, study finds

STAT

Whenever a hematopoietic cell transplant patient tries to get a family member to sneak food in past the nurses, Federico Stella, a resident hematologist at the University of Milan, remembers. One was a girl who tried to get her sister to bring her a panettone, a Milanese sweet bread usually eaten around the holidays. A week before Christmas, the sister tried to hide the panettone in a bag.

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Pharmacists migration to Australia and New Zealand gets easier now with Academically.ai

Pharma Tutor

Pharmacists migration to Australia and New Zealand gets easier now with Academically.ai. admin. Sat, 12/10/2022 - 15:42. Academically.ai, We are an Australian healthcare education technology (EdTech) start-up based in Sydney. We provide courses that will prepare pharmacists to practice, getting a job and migrate to Australia and New Zealand. To put it simply, we intend to enter the Indian market because the majority of pharmacists are underpaid, and many are unaware of such vast potential outsid

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STAT+: Emerging class of genetically targeted drugs induce remissions in leukemia patients

STAT

NEW ORLEANS — An emerging class of genetically targeted drugs is inducing remissions in about one-third of patients with advanced leukemia, according to updates Saturday from separate clinical trials. Two biotechs — Syndax Pharmaceuticals and Kura Oncology — are developing their own versions of so-called menin inhibitors that have the potential to become effective treatments for certain types of genetically defined acute myeloid leukemia (AML), a rapidly progressing bone mar

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Social Determinants of Health Found to Affect In-Hospital Mortality Rates From Pulmonary Embolism

Pharmacy Times

Low socioeconomic status was associated with greater in-hospital mortality and decreased use of advanced therapeutic options.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: ‘We’ve got a new target’: Bispecific antibody for multiple myeloma succeeds in mid-stage trial

STAT

NEW ORLEANS — Researchers had hoped in recent years that a protein called GPRC5D might offer a new way to get the immune system to hunt down and destroy multiple myeloma cells. Now, the results of a Phase 2 study on a bispecific antibody targeting this protein offers confirmation. The data, presented Saturday at the annual American Society of Hematology conferences, wowed a crowd of attendees, including clinicians who began excitedly imagining how to use the new drug in practice.

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ASH: With immune thrombocytopenia win, argenx proves efgartigimod’s no one-trick pony in autoimmune disease

Fierce Pharma

ASH: With immune thrombocytopenia win, argenx proves efgartigimod’s no one-trick pony in autoimmune disease. fkansteiner. Sat, 12/10/2022 - 09:12.

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Phase 3 Trial Data Show Luspatercept Therapy Increased 3-year OS Probability for Patients With IPSS-R Very Low-risk MDS

Pharmacy Times

Expert discusses analysis of phase 3 MEDALIST trial data aimed to assess the probability of greater overall survival and progression-free survival benefit from luspatercept vs placebo.

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ASH: Roche touts Lunsumio's durable efficacy as AbbVie, Regeneron plot lymphoma bispecific battle

Fierce Pharma

ASH: Roche touts Lunsumio's durable efficacy as AbbVie, Regeneron plot lymphoma bispecific battle. aliu. Sat, 12/10/2022 - 22:30.

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Study: Patients of Racial, Ethnic Minority Groups With Diffuse Large B-cell Lymphoma Are Often Excluded From Frontline Therapy Trials

Pharmacy Times

In recent decades, clinical trials have grown increasingly restrictive and exclusive, which has impacted the inclusivity and diversity of selected trial participants.

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STAT+: Progress report on Adicet’s ‘gamma-delta’ T cell therapy shows mixed results on durability of remissions

STAT

NEW ORLEANS — Adicet Bio generated a good deal of buzz last June with a unique, off-the-shelf therapy made from a special type of T cell that induced complete remissions in patients with advanced and aggressive B cell lymphomas. But an update reported Saturday showed patients starting to relapse, which may raise questions about the so-called gamma-delta T cell therapy’s durability.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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HER2 Breast Cancer Therapeutic, OP-1250, Receives Phase 2 Dose Recommendation

Pharmacy Times

Following a phase 2 analysis of OP-1250 with palbociclib, researchers recommend an OP-1250 dose level of 120 mg/day for future trials.

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Doctors on TikTok to Follow in 2023

Board Vitals - Pharmacist

When it comes to medical information, there may not be a more entertaining way to receive it than through a TikTok video. There are many people creating these informative videos, but did you know there are lots of doctors on TikTok that you can follow? And with more than 1.5 billion monthly users (as of Q4 in 2022), TikTok is easily one of the most popular social media sites.

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Breast Cancer Specialist Says Guidelines for HER2 Cancer Subtypes Can Optimize Patient Treatment

Pharmacy Times

Guidelines for HER2-low expressed cancer could define who and how patient recieve drugs, said expert live from San Antonio Breast Cancer Symposium 2022.

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