Sat.Jun 03, 2023

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Analysis of Gut Microbiome Did Not Show Significant Differences Relating to Immune Checkpoint Inhibition Resistance

Pharmacy Times

Fecal microbiota transplant from responders to non-responders was able to rescue immune checkpoint inhibition use in patients with melanoma, with 40% of patients showing clinical benefit.

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ASCO: Seagen's top-selling drug under threat as Bristol Myers' Opdivo beats Adcetris in lymphoma

Fierce Pharma

The rising antibody-drug conjugate class has hit a setback as Seagen’s Adcetris, one of the earliest and fast-growing members of the group, was defeated by immune checkpoint inhibitor. | The rising antibody-drug conjugate class has hit a setback as Seagen’s Adcetris, one of the earliest and fast-growing members of the group, was defeated by immune checkpoint inhibitor in classical Hodgkin lymphoma.

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New Manufacturing Process Could Improve CAR T Cell Efficacy Against Aggressive Form of Leukemia

Pharmacy Times

Expert said that manufacturing the T cells with a tyrosine kinase inhibitor may allow more patients to get allogeneic stem cell transplant, the current best means of long-term cure.

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Cross-border ‘twinning programs’ may reduce survival disparities for childhood leukemia

STAT

CHICAGO – A few miles can mean a life or death difference to children with cancer, if those miles cross a national border. “Twinning programs” helped to reduce survival disparities in childhood acute leukemia between high income and lower income countries, according to a study presented here at the American Society of Clinical Oncology on Saturday.

Hospitals 101
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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Tumor Fraction Retains Strong Prognostic Value for Advanced Non-small Cell Lung Cancer

Pharmacy Times

High tumor fraction after induction chemotherapy identifies a population with an unmet need who has low chances to benefit from immune checkpoint blockades.

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ASCO: J&J, Legend's Carvykti stages stellar show in earlier myeloma. But has the CAR-T reached a ceiling?

Fierce Pharma

After a recent data leak reveale | After a recent data leak revealed a dramatic benefit for J&J and Legend’s Carvykti in earlier treatment of multiple myeloma, the pair has peeled back some even more stunning efficacy results that could further pressure Bristol Myers Squibb’s rival CAR-T therapy, Abecma.

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Expert: Genomic Testing Can Help Oncologists Customize Treatment Based on the Tumor Type

Pharmacy Times

Identifying alterations in tumor genes has enabled medical oncologists to guide patients towards more specific therapies.

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ASCO: Novartis touts Kisqali adjuvant breast cancer data

pharmaphorum

ASCO: Novartis touts Kisqali adjuvant breast cancer data Phil.

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