Wed.Mar 15, 2023

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West Nile, Lyme, and other diseases are on the rise with climate change. Experts warn the U.S. is not prepared

STAT

In the summer and fall of 2021, West Nile virus spread rapidly through Arizona’s Maricopa County and other areas of the state. The outbreak, with more than 1,700 cases reported and 127 deaths. was the largest in the United States since the mosquito-borne virus first emerged in this country in 1999. But with the nation facing a far larger public health crisis with the Covid-19 pandemic, it went almost unnoticed.

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FDA Authorizes Bivalent Pfizer-BioNTech COVID-19 Vaccine As Booster Dose For Young Children

Drug Topics

A new booster shot of the Pfizer-BioNTech COVID-19 vaccine is now available for children aged 6 months to 4 years, in an effort to continue to curb the effects of COVID-19

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Andre Persaud departs Rite Aid

Drug Store News

Bill Miller, senior vice president of central retail operations, will serve as Rite Aid's acting head of retail operations, and Karen Staniforth, chief pharmacy officer, will oversee store pharmacy operations.

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Novel small molecule drug facilitates leukaemia remission

European Pharmaceutical Review

New targeted drug revumenib facilitated complete response in around 40 percent of patients with acute leukaemia subtypes, according to data in a new pair of studies ( 1 ) and ( 2 ) published in Nature. The two genetic subtypes of acute leukaemia involved in this research are “driven by a rearrangement of the MLL1 gene or a mutation in the NPM1 gene.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Biden administration to fine manufacturers of 27 medicines for price hikes

STAT

WASHINGTON — The Biden administration will fine drugmakers who hiked prices faster than the rate of inflation on 27 medications administered in physicians’ offices, the agency said Wednesday. Pfizer had the most drugs on the list of any manufacturer, with five. Seagen’s bladder cancer drug Padcev, which also garnered penalties, will likely soon be in Pfizer’s portfolio, too, after the pharma giant completes its $43 billion acquisition of the Washington state company.

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Barilla celebrates Mikaela Shiffrin with limited-edition pasta pack

Drug Store News

Barilla is celebrating Mikaela Shiffrin’s 87th World Cup victory with a pasta pack that features the brand’s iconic blue box pasta recipe made into 8 and 7 shapes.

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More Trending

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Publix associates help the environment during 2023 Publix Serves Week

Drug Store News

More than 7,500 associates will volunteer at over 200 organizations, including Keep America Beautiful affiliates, parks, zoos, gardens and other nonprofits focused on environmental sustainability.

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Novo Nordisk to cut insulin prices by up to 75% in 2024

Pharmafile

Danish pharmaceutical company Novo Nordisk has announced that it will cut its prices for insulin products by up to 75%, beginning in January 2024. The price of Novolog and Novolog Mix 70/30 will be cut by 75%, with Novolin and Levemir seeing a 65% reduction in price. Novo’s cuts will take effect around the same time that the American Rescue Plan will be introduced.

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Inhaled Fluticasone and CYP3A4 Interactions

Med Ed 101

Fluticasone is one of the most commonly used inhaled corticosteroids for the management of asthma and other respiratory conditions. I’ve encountered drug interactions frequently with fluticasone because it is metabolized by CYP3A4. I’ve seen this interaction flagged on many drug interaction programs. In this article, I’ll discuss the practical implications of dealing with inhaled fluticasone […] The post Inhaled Fluticasone and CYP3A4 Interactions appeared first on Med Ed

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Prenatal leukotriene receptor antagonist use does not increase neuropsychiatric events in offspring

Hospital Pharmacy Europe

Prenatal leukotriene receptor antagonist use has been found to not increase the risk of adverse neuropsychiatric events in their children Prenatal leukotriene receptor antagonist use does not appear to significantly elevate the risk of developing neuropsychiatric events among their offspring according to the findings of a study by Taiwanese researchers.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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RxBenefits unveils Patient Assistance program to lower cost of specialty drugs

Drug Store News

The Patient Assistance solutions ensure patients receive their medications, even if alternative funding is unavailable or they don’t qualify for need-based assistance.

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Pholcodine cough and cold medicines being withdrawn from UK market

Hospital Pharmacy Europe

Pholcodine containing medicines are being withdrawn in the UK by the MHRA after a review suggested the risks outweigh the benefits The opioid pholcodine, is approved for use in adults and children over 6 years of age for a dry or non-productive cough and is also present in some cough and cold remedies. The MHRA in the UK has said that pholcodine containing cough and cold medicines are being withdrawn from the UK market as a precaution following a review and will no longer be available from pharm

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Fezolinetant Appears Successful In Treating Hot Flashes And Night Sweats

Drug Topics

Results from a phase 3 study show that the drug is effective in treating VMS symptoms due to menopause.

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ebook: Nanoparticle formulations: overcoming dissolution challenges

European Pharmaceutical Review

Nanoparticle-based drug formulations are a promising option for drug delivery with numerous beneficial attributes. They have the potential to increase the bioavailability of drugs with low aqueous solubility, target specific cells or tissues, and release drugs in a controlled manner to reduce toxicity. Currently more than 50 nanoparticle therapies are approved for clinical use in the US and Europe.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Biden's 'Cancer Moonshot' is already being fueled by tech addressing breast cancer

Fierce Healthcare

Biden's 'Cancer Moonshot' is already being fueled by tech addressing breast cancer aburky Wed, 03/15/2023 - 12:05

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Level Select intros plant-based OTC brand

Drug Store News

The product line includes Muscle Rub Lotion, Sports Therapy Cream, Sport Recovery Soaking Salts, Massaging Roll-On Gel and Extended Relief Patches.

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Opinion: AI chatbots can improve health — but only with help from humans

STAT

Chatbots like OpenAI’s ChatGPT can hold fun conversations across many topics. But when it comes to providing people with accurate health information, they need help from humans. As tech enthusiasts who research and develop AI-driven chatbots in health care, we are optimistic about the role these agents will play in providing consumer-centered health information.

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Kroger provides autonomous delivery in Dallas alongside Gatik

Drug Store News

Gatik’s medium-duty autonomous box trucks will transport products from a Kroger customer fulfillment center in Dallas to multiple retail locations.

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STAT+: In Minnesota, researchers explore how to audit health AI models on a patient level

STAT

As hospitals and companies continue t o leverage artificial intelligence in medicine, researchers are also grappling with how to check the AI systems to protect patient safety.  “Risk management is a tricky business,” said Gyorgy Simon, scientific co-director for the University of Minnesota’s clinical AI program. “Treatment models are changing, the population is changing.

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ONC, CMS officials plot next reforms to entice adoption of electronic prior authorization

Fierce Healthcare

ONC, CMS officials plot next reforms to entice adoption of electronic prior authorization rking Wed, 03/15/2023 - 13:08

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Opinion: Drug developers navigating ‘biology’s century’ need a model. We made one

STAT

STAT’s Matthew Herper struck an industry nerve when he wrote that the drug development industry is “not prepared for the next wave of biotech innovation.” His report ends on a somewhat dismal note: the industry is long on diagnosis (clinical development is too expensive) and short on cures.

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US District Judge Hearing Arguments to Potentially Halt Distribution of Abortion Pill Mifepristone

Drug Topics

Drug Topics will continue to update this story as new information becomes available.

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Long-used abortion pill in U.S. under threat in Texas lawsuit

STAT

AMARILLO, Texas — A conservative judge in Texas raised questions Wednesday about a Christian group’s effort to overturn federal regulators’ decades-old approval of a leading abortion drug , in a case that could threaten the country’s most common method to end pregnancies. Judge Matthew Kacsmaryk heard more than four hours of debate over the Alliance Defending Freedom’s request to revoke or suspend the Food and Drug Administration’s approval of mifepristo

FDA 84
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Zipline's new drone brings Rx deliveries to Michigan Medicine, Intermountain and MultiCare patients

Fierce Healthcare

Zipline's new drone brings Rx deliveries to Michigan Medicine, Intermountain and MultiCare patients aburky Wed, 03/15/2023 - 16:04

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Revlon unveils beauty tools to support people with limited hand mobility, joint pain

Drug Store News

The Comfort + Control tools are easy to maneuver, comfortable to hold and provide users with maximum control, the company said.

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Clever Care nabs $41M to scale up Medicare Advantage plans integrating Eastern and Western medicine

Fierce Healthcare

Clever Care nabs $41M to scale up Medicare Advantage plans integrating Eastern and Western medicine hlandi Wed, 03/15/2023 - 07:57

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AbbVie's Humira, 5 Pfizer drugs among those with price hikes that exceeded inflation rate

Fierce Pharma

AbbVie's Humira, 5 Pfizer drugs among those with price hikes that exceeded inflation rate kdunleavy Wed, 03/15/2023 - 10:09

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Kellogg unveils names for snack, cereal companies ahead of spinoff

Drug Store News

The global snacking business will be named Kellanova, and the North American cereal business will be named WK Kellogg Co.

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STAT+: Would the federal government defer to states to regulate PBMs?

STAT

WASHINGTON — After years of struggling to regulate the drug middlemen that create pharmacy networks, the federal government could lean on states to rein them in — even, potentially, in Medicare. The Department of Justice has until next month to tell a federal appeals court where the administration stands on the issue. Insurers determine what drugs are covered, where their customers can obtain these drugs, and how much drug costs their customers must pay for.

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Pfizer adjusts EU vaccine deal but still wants payment for undelivered doses: FT

Fierce Pharma

Pfizer adjusts EU vaccine deal but still wants payment for undelivered doses: FT esagonowsky Wed, 03/15/2023 - 08:43

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Opinion: Listen: Big changes for First Opinion

STAT

After two years as host of the “First Opinion Podcast” and many more as the founding editor of STAT’s expansive, authoritative First Opinion platform, Pat Skerrett put down his editing pen and microphone to start a new chapter — retirement. Pat bade us farewell with a favorite quote from Maurice Sendak’s “Where the Wild Things Are”: “Let the wild   rumpus start!

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Cough medicines containing pholcodine withdrawn across UK

Pharmafile

Some cough syrups being sold behind the counter at pharmacies are being withdrawn due to safety concerns surrounding potential allergies to an ingredient called pholcodine. Some experts have explained that certain people could experience allergic reactions to pholcodine, and are recommending that the public check the packaging of any and all cough tablets or syrups they may have at home to check if pholcodine is within the ingredients.

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How states approach Medicaid eligibility redetermination will have big implications for enrollees: KFF analysis

Fierce Healthcare

How states approach Medicaid eligibility redetermination will have big implications for enrollees: KFF analysis hlandi Wed, 03/15/2023 - 18:07

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BlueRock Therapeutics collaboration over Parkinson’s disease digital health technology

Pharmafile

Clinical stage biopharmaceutical company BlueRock Therapeutics has announced a collaboration with Rune Labs and Emerald Innovations. It will look at using wearable and invisible contactless digital health technology to aid clinical trials researching Parkinson’s disease.