Tue.Jan 24, 2023

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Can machine learning accelerate drug formulation?

Outsourcing Pharma

Research emerging from the University of Toronto found that using machine learning models was able to guide the design of long-acting drug formulations.

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Amazon Pharmacy intros RxPass for generic medications

Drug Store News

RxPass is a new Prime membership benefit from Amazon Pharmacy offering patients affordable access to commonly prescribed generic medications for more than 80 common health conditions.

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Trending Sources

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STAT+: ‘I’m just disgusted’: How alleged sexual misconduct stole one student’s passion for academic science

STAT

It was the summer of 2020, and she couldn’t have scripted a better start as a new M.D.-Ph.D. student — at least until everything went so very wrong. She’d just been admitted to Washington University in St. Louis. And for a young trainee fascinated with the complex crosstalk between the immune and nervous systems, she’d struck scientific gold — the chance to work in one of the world’s top neuro-immunology labs.

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AmerisourceBergen changes name to Cencora

Drug Store News

The new name represents a unified presence that will continue to fuel the company’s ongoing growth strategy and advance its impact across health care, the company said.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Can dogs get sore throats?

The Checkup by Singlecare

One of the worst harbingers of sickness is the sore throat. We all know the dread you feel when you wake up in the morning with a hoarse voice and not being able to swallow without stabbing pain. You might wonder if your dog can also get this cruddy symptom of illness or overuse. The answer is yes. Fortunately, many of the same methods for recovery apply as well, though with some pet-friendly modifications.

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The drug was meant to save children’s lives. Instead, they’re dying

STAT

Emily was combing her baby daughter’s hair when she first felt the lumps. It was a week before Christmas, and her youngest daughter, Isadora, had been feverish and listless, unwilling to play or take a bottle. The lumps were clustered on the back of Isadora’s neck, the size of small beans. Something was very wrong. At an urgent care clinic, the doctor found more lumps under Isadora’s arms and in her groin.

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Predictive biomarkers could ease the exhaustive trial-and-error of antidepressants

STAT

When a patient is suffering from depression and considering medication, practically all physicians have the same go-to treatment: a selective serotonin reuptake inhibitor. Patients start on a low dose and slowly increase it. It may take weeks for the drug to work, if it works. If not, a cycle begins. Wean off the SSRI, wean onto a new medication. All the while, the patient must manage depressive symptoms along with any side effects of a medication, which, counterintuitively, can include suicidal

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Nine for 2023, part three: thriving or surviving?

pharmaphorum

In this final instalment of IQVIA EMEA Thought Leadership’s Nine for 2023 three-part series, focusing on issues that will change the direction of healthcare and the pharmaceutical industry this year, three key competitive issues for pharmaceutical companies in 2023 are assessed. 1. Competing for attention: Bandwidth stress Healthcare systems will continue to be hugely stretched in 2023, and that limits the engagement that pharmaceutical companies have with healthcare professionals to promote the

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Opinion: It’s time to retire ‘poor historian’ from clinicians’ vocabularies

STAT

Should we pity the “poor historians” — the individuals or family members who can’t give a clear accounting of their illness or symptoms — or embrace them? They have important stories to offer their clinicians, but can’t tell them. Who is really to blame here? And should the term poor historian ever be part of an individual’s permanent record?

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Largest global clinical site hires all-female key leaders in Europe

European Pharmaceutical Review

Velocity Clinical Research , the largest integrated research site organisation globally, has made three all-female key leadership hires. This move strengthens its European senior executive team as the firm continues its expansion in the region. The three new European hires are: Maria Lehretz, Medical Director, Velocity Leipzig, Germany Maria has nearly a decade of experience as a clinical research physician, and has worked on approximately 70 clinical trials.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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AAM report: Middlemen increasingly block patient access to new generics

Drug Store News

The new report shows the extent to which plans and PBMs delay patient access to lower-cost generics.

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Can genetic data be a magic bullet for drug R&D?

pharmaphorum

Drug development has long been an issue for the pharma industry, due to the expense and the high failure rate of potential treatments. Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates. Recent years have brought a revolution to the way in which patients receive treatment.

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Amazon Prime for your prescriptions, virtual care during pregnancy, & AI for mental health

STAT

You’re reading the web edition of STAT Health Tech, our guide to how tech is transforming the life sciences.  Sign up to get this newsletter  delivered in your inbox every Tuesday and Thursday.

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Lilly injects $450m into plant making Mounjaro

pharmaphorum

Eli Lilly is leaving nothing to chance when it comes to making the most of its fast-growing diabetes therapy Mounjaro – it is investing another $450 million at a facility in North Carolina that will make the drug. The plant in Research Triangle Park has already received hefty investment from Lilly, and the new tranche will take the tally to $1.7 billion since 2020.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharmaceutical Microbiology Publications

Pharmig

Pharmig provides useful guides, publications and factsheets for the Pharmaceutical sector. Our membership options include online training and many other useful benefits. The post Pharmaceutical Microbiology Publications appeared first on Pharmig.

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Pepsi debuts improved Pepsi Zero Sugar

Drug Store News

The upgraded recipe uses a new sweetener system to land a more refreshing and bolder taste profile than the previous Pepsi Zero Sugar varietal, the company said.

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STAT+: Amazon Pharmacy expands with new $5 monthly prescription service

STAT

Amazon is launching a new prescription service that lets patients on Amazon Prime get eligible generic medications for a $5 monthly subscription, including free delivery. The program, called RxPass, is the latest addition to Amazon’s growing line of direct-to-consumer health care businesses. In November, the company announced the launch of Amazon Clinic, a telehealth service that lets patients message with a third-party provider to get prescriptions for common conditions.

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With the X-waiver repealed, officials urge providers to begin prescribing buprenorphine for opioid addiction

Fierce Healthcare

With the X-waiver repealed, officials urge providers to begin prescribing buprenorphine for opioid addiction dmuoio Tue, 01/24/2023 - 14:52

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STAT+: Health systems have much higher prices, only marginally better quality, new study finds

STAT

The claims have become almost ubiquitous. Hospital CEO after hospital CEO stands at a podium and promises the merger being announced will improve quality and lower costs. Once deals close, though, there tends to be little, if any, follow-up to determine whether those things actually happened. A new Journal of the American Medical Association study adds to the growing body of evidence that they don’t.

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Physician Opinions on Burnout in 2022 – Blog

InCrowd

In November of 2022, InCrowd surveyed 500 US physicians to track burnout. In 2022, reports showed that physician burnout had risen to frightening levels. In November of that year, InCrowd surveyed US physicians to understand how physicians are managing work-related stress and burnout, to explore physician feelings on their profession, and better understand how medical facilities can address physician burnout.

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Technology could improve pregnancy care for low-income patients — if health systems can pay for it

STAT

For low-income patients, the challenges of pregnancy are only compounded by the challenges of prenatal care: the dozen or so doctors’ appointments, the time off work or childcare, the cost of parking and public transit. “Even just getting to appointments can be huge trouble,” said Kathryn Marko, an OB-GYN at George Washington, a Washington, D.C.

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Health Tech to Look Out for in 2023

Drug Topics

Preventive care, health insurance literacy and a digital health shakeout are in the crystal ball

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STAT+: Pharmalittle: Amazon adds $5 monthly generic drug subscription; PhRMA ends lobbying contract with brother of White House official

STAT

Rise and shine, everyone, another busy day is on the way. We can tell thanks to the cacophonous sounds of traffic passing the Pharmalot campus, where the official mascot is stalking squirrels and waiting for a playdate. As for us, we are brewing cups of stimulation — our choice today is macadamia nut — and foraging, as usual, for items of interest.

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Hospital, health system boards saw low turnover, slow diversity gains from 2018-2022, AHA finds

Fierce Healthcare

Hospital, health system boards saw low turnover, slow diversity gains from 2018-2022, AHA finds dmuoio Tue, 01/24/2023 - 10:23

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STAT+: Doctors’ group complains that 60 Minutes segment on Wegovy was really just an ad

STAT

A physicians’ group has filed a complaint with the Food and Drug Administration alleging that a recent 60 Minutes segment about the Wegovy weight-loss drug was actually an advertisement and demanded the agency withdraw the report from circulation. At issue was a Jan. 1 segment on the widely watched CBS News program about the Novo Nordisk drug, which is on its way to becoming a top-selling medicine and has experienced shortages due to high demand.

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Spending on Cancer Drugs Expected to Nearly Double in the Next Five Years Worldwide

Drug Topics

Biosimilars will have limited effect on the oncology drug expenditures, according to IQVIA. Spending on obesity drugs may increase tenfold, depending on guidelines and payer coverage.

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STAT+: New results show Cassava’s Alzheimer’s drug has placebo-like efficacy

STAT

Cassava Sciences had long claimed that its experimental treatment for Alzheimer’s disease was capable of improving the cognition of patients — a benefit no other Alzheimer’s drug has ever shown. But mid-stage study results updated on Tuesday now show the cognitive status of patients worsening to the point where Cassava’s drug, called simufilam, doesn’t look any more effective than a placebo.

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Dollar Tree appoints new CEO

Drug Store News

Dollar Tree CEO Mike Witynski is stepping down from his position and executive chairman Rick Dreiling will assume the top job, effective Jan. 29.

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STAT+: Many pediatric drug study results were never posted to a U.S. government database

STAT

Amid ongoing controversy over clinical trial transparency, a new analysis found that results of 43 studies involving thousands of children were never reported to a U.S. government database or published in the scientific literature. In some cases, medicines being studied were for such life-threatening conditions as congenital heart disease and Duchenne muscular dystrophy.

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AstraZeneca’s newest asthma launch fills a gap as generics chip away at respiratory flagships

PharmaVoice

A longtime leader in the respiratory space, AstraZeneca has hammered another stake in the ground with its newest asthma treatment, Airsupra.

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STAT+: Calico looking for new chief scientist after celebrated biologist David Botstein quietly retires

STAT

Are you a promising middle or late-career scientist with a desire to extend human lifespan, experience leading a large organization, and a fondness for naked mole rats? Calico, Google’s aging research spinout, could maybe use your resume. The massively funded research and development company is without a chief scientific officer after the celebrated biologist David Botstein quietly retired last year.

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Industry Voices—Key to rural hospital survival: Sustainable solutions for patient financial engagement

Fierce Healthcare

Industry Voices—Key to rural hospital survival: Sustainable solutions for patient financial engagement hlandi Tue, 01/24/2023 - 09:47

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Promising gene therapy delivers treatment directly to brain

STAT

When Rylae-Ann Poulin was a year old, she didn’t crawl or babble like other kids her age. A rare genetic disorder kept her from even lifting her head. Her parents took turns holding her upright at night just so she could breathe comfortably and sleep. Then, months later, doctors delivered gene therapy directly to her brain.

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Batiste helps refresh hair with overnight solutions

Drug Store News

Batiste’s new launches include Dry Shampoo in Overnight Deep Cleanse, Leave-In Overnight Hair Mask and Dry Shampoo in Texturizing.

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