Mon.Apr 03, 2023

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Amazon Teams Up With Pharma Giants For Coupons On Branded Drugs

Drug Topics

The new feature automatically applies manufacturer-sponsored coupons directly to an eligible patient’s order. So far, only a few pharma companies have made their coupons available through Amazon.

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Empowering Women: 5 Compelling Reasons Women Pursue a Career in Pharmacy

Pharmacy Is Right For Me

Pharmacy is a field of study and practice that may have historically been male-dominated, but now an estimated 65% of pharmacists in the United States are women! And there are many benefits to women who pursue pharmacy as a career. Job stability and growth Pharmacy is a rapidly growing field that’s expected to continue to grow in the coming years. The Bureau of Labor Statistics projects that the employment of pharmacists will increase by 3% from 2020 to 2030.

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Hospitals pledge to protect patient privacy. Almost all their websites leak visitor data like a sieve

STAT

Every hospital in America promises to protect the privacy of its patients and the details of their medical care. And almost every one of them uses sophisticated data tools to track and share the personal information of visitors as soon as they start clicking on their websites. A new study found that 99% of U.S. hospitals employed online data trackers in 2021 that transmitted visitors’ information to a broad network of outside parties, including major technology companies, data brokers, an

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Texas District Judge Vetoes Free Preventive Care Services

Drug Topics

The ruling states that insurers and employers who run plans for employees will have a choice over how- and whether- to cover certain routine screenings, exams and tests.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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1 in 6 people experience infertility worldwide, according to WHO report

STAT

One in six people across the globe face infertility at some point in their lifetime, according to the first new estimates from the World Health Organization in a decade. The prevalence is “staggering,” Pascale Allotey, director of sexual and reproductive health and research at WHO, said at a press conference Monday. The report estimates that 17.8% of adults in high-income countries and 16.5% in low- and middle-income countries experience infertility.

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After Johnson & Johnson loses again in bankruptcy case, it's game on for talc lawsuits

Fierce Pharma

After Johnson & Johnson loses again in bankruptcy case, it's game on for talc lawsuits kdunleavy Mon, 04/03/2023 - 06:44

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Latest WHO Covid-19 vaccine guidance may decrease future demand

Pharmaceutical Technology

The World Health Organisation (WHO) has revised its recommendations regarding the use of Covid-19 vaccines following a meeting of the agency’s Strategic Advisory Group of Experts on Immunisation (SAGE). The latest guidance applies to the current phase of the pandemic and reflects the impact of the Omicron variant, which has led to high levels of immunity in all age groups through both vaccination efforts and infections across the globe.

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STAT+: Vertex, CRISPR Therapeutics inch ahead of rival for genetic fix to sickle cell disease

STAT

The first CRISPR treatment for sickle cell disease has been submitted to the Food and Drug Administration, beating a rival gene therapy that’s been delayed due to a manufacturing issue. On Monday, Vertex Pharmaceuticals and its partner CRISPR Therapeutics said they had met their previously announced goal of filing by the end of March a marketing application for their therapy known as exa-cel.

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FDA-Approved Konvomep Releases To Public

Drug Topics

The drug is a rare FDA-approved liquid formulation that treats ulcers and lowers risk of gastrointestinal bleeding in chronically ill patients.

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STAT+: A devastating skin condition could soon get its first medication, as the frontiers of gene therapy expand

STAT

Wounds have been a constant fact of Aaron Owens’ life. His skin is so fragile that friction that would be trivial to others — rolling over in bed, weight shifting against the seat as the car turns — could scrape off his tissue. He didn’t like being in public sometimes because people would stare at the boy covered in bandages.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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EC grants marketing authorisation for Sandoz’s biosimilar Hyrimoz

Pharmaceutical Technology

The European Commission (EC) has granted marketing authorisation for Sandoz’s biosimilar Hyrimoz (adalimumab) citrate-free high-concentration formulation (HCF). Hyrimoz has been approved for use in all the indications covered by the reference medicine Humira, including plaque psoriasis, rheumatic diseases, ulcerative colitis, Crohn’s disease, uveitis and hidradenitis suppurativa.

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Why the early tests of ChatGPT in medicine miss the mark

STAT

ChatGPT has rocketed into health care like a medical prodigy. The artificial intelligence tool correctly answered more than 80% of board exam questions, showing an impressive depth of knowledge in a field that takes even elite students years to master. But in the hype-heavy days that followed, experts at Stanford University began to ask the AI questions drawn from real situations in medicine — and got much different results.

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Can apple cider vinegar lower your blood pressure?

The Checkup by Singlecare

When you have high blood pressure , it’s important to do what you can to bring it down to a healthier level, since people with high blood pressure have an increased risk of heart disease, heart attack, and strokes. If you’ve adjusted your diet, increased your exercise, reduced stress, and started an antihypertensive medication like propranolol or lisinopril but are still struggling to maintain a healthy blood pressure, consider adding one more treatment to your regimen: apple cider vinegar.

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Opinion: Emergency rooms need clear guidelines about how to handle law enforcement

STAT

The patient arrived in the trauma bay with gunshot wounds to his chest and abdo­men. “Doctor, please don’t let me die today,” he begged me. But I couldn’t give him my full attention, because he was accompanied by two armed officers who were interrogating him and searching his clothing as their body-worn cameras recorded.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Sartorius upscales gene therapy prowess with $2.6bn Polyplus acquisition

Pharmaceutical Technology

Sartorius , through its French listed sub-group Sartorius Stedim Biotech , has signed an agreement to acquire Polyplus for €2.4bn ($2.6bn). The deal will see Polyplus join the German life science group’s portfolio allowing the latter to leverage expertise in transfection reagents and plasmid DNA for gene therapy. Polyplus, based in Strasbourg, France, produces key components in the production of viral vectors used in cell and gene therapies.

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Oral vitamin D fails to improve disease severity in psoriasis

Hospital Pharmacy Europe

Supplementing with oral vitamin D did not appear to improve disease severity in patients with psoriasis according to the findings of an RCT In a randomised trial by Norwegian researchers, it was found that giving oral vitamin D throughout the winter months to patients with psoriasis, despite increasing serum levels of the vitamin, did not lead to an improvement in disease severity.

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BioNTech and DualityBio team up to develop ADC therapeutics for cancer

Pharmaceutical Technology

BioNTech has signed exclusive licence and collaboration agreements with Duality Biologics (DualityBio) for the development of two antibody-drug conjugate (ADC) assets for solid tumours. The agreements also include the manufacturing and commercialisation of the two assets, including DB-1303 and DB-1311, across the globe. As part of the new deals, BioNTech will have commercial rights to the ADCs worldwide, excluding mainland China, the Hong Kong special administrative region and the Macau special

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Investigational combination xanomeline-trospium effective in schizophrenia

Hospital Pharmacy Europe

Xanomeline-trospium an oral, investigational M1/M4-preferring muscarinic agonist significant improved symptoms in patients with schizophrenia In a press release from the manufacturer Karuna Therapeutics , it was announced that its lead investigational therapy for schizophrenia, xanomeline-trospium, demonstrated a statistically significant and clinically meaningful reduction in Positive and Negative Syndrome Scale (PANSS) total score compared to placebo.

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Eisai and National Cancer Center partner for tazemetostat clinical research

Pharmaceutical Technology

Eisai and the National Cancer Center have signed an agreement to partner on investigator-initiated clinical research for the anti-cancer agent, tazemetostat (Tazverik Tablets 200 mg), based on the Patient-Proposed Healthcare Services system. Under this system, patients can request the government for access to medical treatment using unapproved drugs not covered by insurance.

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Nirmatrelvir treatment decreases risk of developing post-COVID-19 condition

Hospital Pharmacy Europe

Nirmatrelvir treatment for patients with COVID-19 has been found to also reduce the risk of developing most post-COVID-19 condition symptoms US researchers from St Louis, Missouri have found that nirmatrelvir treatment during the acute phase of a COVID-19 infection, reduces the subsequent risk of developing post-COVID-19 condition or long covid. Post-COVID-19 condition or long COVID is an often debilitating illness that occurs in at least 10% of those infected with the virus and is estimated to

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Ablaze Pharmaceuticals to develop drug candidate for liver cancer

Pharmaceutical Technology

Ablaze Pharmaceuticals is set to develop a new GPC3-targeted peptide drug candidate for the treatment of liver cancer in China. The company is licensing the first-in-class drug candidate under an existing deal with RayzeBio. The agreement allows Ablaze to clinically develop and commercialise the drug in Greater China. It is based on RayzeBio’s specialisation in targeted radiotherapy (TRT) discovery and Ablaze’s know-how in therapeutic product clinical development, as well as on the radiopharmace

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Aluminum and Alzheimer’s: The Connection Gets Stronger!

The People's Pharmacy

Those old enough to remember the 1960s and 70s may recall that there were concerns about exposure to food cooked in aluminum pots and pans. The rumors were that aluminum could contribute to Alzheimer’s disease. Many neuroscientists rejected the idea of an aluminum and Alzheimer’s disease connection. The Alzheimer’s Association calls it Myth 4 and currently states on its website : “…studies have failed to confirm any role for aluminum in causing Alzheimer’s.

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STAT+: FTC tells Illumina to divest Grail, boosting Icahn’s case

STAT

The U.S. Federal Trade Commission on Monday ordered DNA sequencing giant Illumina to divest Grail, a cancer diagnostics firm it purchased without regulatory approval, saying the $7.1 billion acquisition “would stifle competition and innovation in the U.S. market for life-saving cancer tests.” Illumina purchased Grail in August 2021 without clearances from either the FTC or European regulators, who also appear to be preparing to tell Illumina to divest the cancer diagnostics firm.

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Stop & Shop adds Flashfood program to more than 60 New York locations

Drug Store News

Stop & Shop is adding the Flashfood program to more than 60 of its stores across Long Island, New York City, Westchester County and the Hudson Valley.

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After rumored merger fell through, Merck and Seagen's Padcev-Keytruda combo wins bladder cancer nod

Fierce Pharma

After rumored merger fell through, Merck and Seagen's Padcev-Keytruda combo wins bladder cancer nod fkansteiner Mon, 04/03/2023 - 18:10

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Almost every hospital's homepage is sending visitor's data to third parties, study finds

Fierce Healthcare

Almost every hospital's homepage is sending visitor's data to third parties, study finds dmuoio Mon, 04/03/2023 - 13:32

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Walmart's website, app gets a makeover

Drug Store News

Walmart is rolling out a completely redesigned homepage, building a customer-centric and curated storefront on walmart.com and the Walmart app.

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CHMP meeting highlights – March 2023

European Pharmaceutical Review

Nine new medicines were recommended for approval in the European Medicines Agency (EMA)’s Committee for Medicinal Products for Human Use (CHMP) March meeting, Medicines recommended for approval at the CHMP meeting The CHMP recommended authorising the COVID-19 vaccine Bimervax (previously COVID-19 Vaccine HIPRA) as a booster in individuals over 16 years old, who have previously been vaccinated with a mRNA COVID-19 vaccine.

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Kroger delivery expands to Austin, Texas

Drug Store News

Kroger has opened a new facility serving the greater Austin area, welcoming nearly 70 new associates.

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USP Updated Guidelines

Drug Topics

The long-awaited revised USP guidelines will become official on November 1, 2023.

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STAT+: A young boy’s nightmare diagnosis, and the $3 million one-time treatment that will likely save his life

STAT

When the long-awaited moment arrived, a nurse helped Adam Hess loosen a tiny plastic clamp on an intravenous line leading to the chest of his son, who lay asleep in a bed at Boston Children’s Hospital. Millions of stem cells that were collected from 6-year-old Conner Hess’s blood in January flowed through the IV and entered his bloodstream.

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Treatment shows strong potential for ALK-driven neuroblastoma

European Pharmaceutical Review

Lorlatinib has shown to be safe and effective in treating high-risk neuroblastoma in a Phase I trial. These results have led to a major amendment in a European Phase III paediatric clinical trial. In the Phase I New Approaches to Neuroblastoma Therapy (NANT) trial, researchers found that lorlatinib given alone or in combination with chemotherapy was safe and tolerable in patients with relapsed/refractory anaplastic lymphoma kinase (ALK)-driven neuroblastoma.

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Amid dispute with FDA, Akebia proposes new dosing for oral anemia drug in kidney disease

Fierce Pharma

Amid dispute with FDA, Akebia proposes new dosing for oral anemia drug in kidney disease aliu Mon, 04/03/2023 - 11:12

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How to Use Melatonin to Ease Reflux

The People's Pharmacy

Millions of Americans experience heartburn, either occasionally or on a regular basis. Most people are aware of OTC medicines to treat this uncomfortable condition. However, some would prefer an alternative way to address their reflux. Could melatonin help? Melatonin Successful for Nighttime Reflux: Q. You have written about a study comparing PPIs with melatonin.

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