Fri.Nov 04, 2022

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Let’s Not Sugar Coat It: HbA1c is the Imperfect Diabetes Diagnostic

Pharmacy Times

When diabetes is uncontrolled, higher percentages of hemoglobin become glycated, which causes elevated HbA1c and glucose levels to rise within the body.

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Pfizer, BioNTech report bivalent Covid-19 booster more protective than original vaccine

STAT

New data from Pfizer and BioNTech on their bivalent Covid-19 vaccine suggests the updated product may be more protective against more recent Omicron subvariants than the original version of the vaccine, the companies said in a statement released Friday. The companies said the levels of neutralizing antibodies that target the BA.4 and BA.5 subvariants of the SARS-CoV-2 virus were four-fold higher in people aged 55 and older who received the bivalent booster than in similarly aged people who recei

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Relationship Between Psoriasis, Kidney Damage Remains Unclear

Pharmacy Times

Psoriasis and end-stage renal disease are believed to share multiple pathogenic pathways, including various cytokines, reactive oxygen species, and psoriasis medications.

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Pharmacists Challenged With Amoxicillin, Adderall Shortages

Drug Topics

Shortages are leaving patients in the lurch.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Respiratory Syncytial Virus Infection in the Pediatric Population

Pharmacy Times

Infection with RSV can take a variety of forms, ranging from a mild upper respiratory tract infection to severe, life-threatening acute respiratory failure.

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Why blockchain is big pharma’s big focus

pharmaphorum

To address the supply chain vulnerabilities of the pharma industry, an innovative, collaborative blockchain-based system could help to keep track of drugs in transit and ensure they are stored in the correct conditions. The pace of technological advancement and focus in this area suggests that such a solution could be coming soon. While most supply chains were impacted by the Covid-19 pandemic, the demands it placed on pharmaceutical and medical supply chains were immense and underlined the impo

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STAT+: A ‘blank check’: Bill to boost antibiotic development blasted as a ‘flawed’ giveaway to pharma

STAT

Amid mounting concern over antibiotic resistance, a coalition of academics and advocacy groups is urging Congress not to pass legislation to reward drug companies for developing new treatments, because they argue the bill fails to require acceptable clinical trial standards and is tantamount to a giveaway to the pharmaceutical industry. The legislation, known as the Pasteur Act, would encourage drug development by creating a subscription-style business model in which the U.S. government offers u

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Social Isolation May Be Associated with Worse Outcomes in Heart Failure Patients

Pharmacy Times

Among heart failure patients, those who were at risk of social isolation had a worse attitude about advance care planning.

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How doulas could help prevent the harms that can happen during childbirth

STAT

When Tamiya Griffin was expecting her first child in 2014, she had what she thought was a straightforward plan: deliver at the hospital down the road, the same place her mother gave birth to her. But when Griffin, then a 22-year-old senior in college, went into labor a few weeks early, she had to undergo an emergency C-section.  “And that was not a part of my plan.

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Study Links Hormone Therapy With Depression in Women Undergoing Menopause

Pharmacy Times

Systemically administered hormonal therapy may be associated with a greater risk of depression before and during menopause.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Opinion: Millions of Americans have health insurance that isn’t ‘good enough’

STAT

The open enrollment season for health insurance is gearing up at a time when more people in the United States have health insurance than ever before. Yet millions of Americans who enroll this fall still won’t be able to easily afford the health care they need or will be hit with medical bills they can’t pay. Why? Because whether you have health insurance through an employer, the individual market, or even through Medicare, high health care costs and coverage exclusions are making i

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What can Rishi Sunak do for the UK’s pharma industry

Pharmaceutical Technology

Last week, after a tumultuous 45 days under Liz Truss’s control , the role of the UK’s Prime Minister (PM) was passed on to Rishi Sunak , in a bid to restore balance to the British economy. During her short reign, Truss’s cabinet had promised a £45 billion ($51.59 billion) mini-budget that included unfunded tax cuts for the rich, enacted a U-turn on an energy price freeze, and oversaw the largest drop in value for the British pound against the US dollar.

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‘Our community is supported at the highest levels’: Adm. Rachel Levine on gender-affirming care

STAT

BOSTON — As the health and safety of trans and queer youth are jeopardized across the country, there were a few minutes of hope on Wednesday in Boston when Adm. Rachel Levine , the assistant secretary for health at the Department of Health and Human Services and first transgender federal official confirmed by the U.S. Senate, visited the Boston Alliance of LGBTQ+ Youth.

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Psilocybin improves depression symptoms, study shows

European Pharmaceutical Review

A new report in the New England Journal of Medicine for the largest-ever trial observing the effects of psilocybin in patients with treatment-resistant depression, found participants reported reduced depressive symptoms three weeks after being given 25mg of psilocybin (COMP360) in combination with psychological support. The multi-centre, Phase IIb trial observed the severity of depression in 233 individuals over 12 weeks in 22 sites and 10 countries across Europe (Czech Republic, Denmark, German

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Following your gut: How scientists are getting closer to linking the microbiome and chronic diseases

STAT

We never walk alone. Across the landscape of our bodies, trillions of microbes accompany us on the journey of life, some of them riding it out in the body’s soft bits from first to dying breath.  A decade or so ago, the human microbiome was a revolutionary concept. Its unknown links to disease intrigued researchers across the globe. Now, some microbiome researchers are trying to usher in a new phase, in which modern tools and analytical approaches can show the connection between micr

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FDA Grants Elranatamab With Breakthrough Therapy Designation for Relapsed or Refractory Multiple Myeloma

Pharmacy Times

Elranatamab is a B-cell maturation antigen (BCMA)-CD3-targeted bispecific antibody.

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Opinion: Believers in science must take action when recommendations breach public health

STAT

Medical practitioners and public health officials work within boundaries that, when crossed by others, can harm the people they are entrusted to protect. When these red lines are crossed, the medical and scientific community can — and should — speak out against it. This process recently played out in Florida following a warning by the state’s Surgeon General that young adult men should not be vaccinated against Covid-19 by mRNA vaccines, the most commonly administered Covid-

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Contributing Factors That May Lead to Severe COVID-19 Infection

Drug Topics

Experts discuss comorbidities as risk factors for patients developing severe COVID-19 symptoms.

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STAT+: Pharmalittle: Europe approves a Sanofi and AstraZeneca RSV shot; CDC updates opioid prescribing guidelines

STAT

And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is still shaping up. For now, we plan to putter around the castle, promenade extensively with the official mascot, and hold a listening party with Mrs. Pharmalot. And what about you?

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Long-Term Adverse Events from COVID-19 Infections

Drug Topics

Medical experts discuss potential long-term adverse effects associated with COVID-19.

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STAT+: U.S. Supreme Court gives Amgen a boost by agreeing to review a closely watched patent case

STAT

In a boost for Amgen, the U.S. Supreme Court on Friday agreed to hear a case in which the company argued a federal appeals court incorrectly determined its patent claims on a cholesterol medication are invalid. At issue is a long-running battle between Amgen and a pair of rivals — Sanofi and Regeneron Pharmaceuticals — over the market for injectable cholesterol treatments.

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Diet Low in Potassium May Not Treat Hyperkalemia, Chronic Kidney Disease

Pharmacy Times

Researchers outline new findings about the connection between hyperkalemia and renin-angiotensin-aldosterone system inhibitors during a session at ASN Kidney Week.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.  That’s right. Send us your changes, and we’ll find a home for them.   Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Solving the taxing problems of taxanes?

European Pharmaceutical Review

Despite advances with targeted and immuno-oncology therapies, chemotherapies remain a cornerstone of cancer treatment for many tumour types – a reflection of their significant anti?tumour effects. Nevertheless, chemotherapy’s disadvantages, including substantial toxicities, combined with inconvenient hospital-based intravenous (IV) administration, impede patients’ ability to stay on treatment and their quality of life.

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Mitigating Population Risk for COVID-19

Drug Topics

Drs Rothholz and Goad discuss population health strategies for COVID-19.

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Expert Suggests Precision Medicine is a Highly Desirable Goal for Dialysis Patients

Pharmacy Times

Applying the principles of precision medicine to peritoneal dialysis could improve the flexibility and personalization of care for dialysis patients.

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News Roundup: October 31 to November 4

Drug Topics

Your weekly roundup of the latest news from Drug Topics®.

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Hepatitis B Vaccination Program Demonstrates Positive Impact

Pharmacy Times

WHO has released a global plan for hepatitis B elimination by 2030, including goals to increase pediatric and maternal immunization and to improve screening and treatment.

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The other ‘D’ in DE&I

PharmaVoice

How companies can work to include people with disabilities into broader equity aims.

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Triplet Regimen With Durvalumab May Increase Overall Survival of Patients with Fatal Intrahepatic Cholangiocarcinoma

Pharmacy Times

Promising data suggest triplet regimens may more effectively treat patients with unresected and metastatic intrahepatic cholangiocarcinoma.

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Unlocking the full power of data for Pharma

pharmaphorum

The value of data has never been greater in healthcare. With greater digital engagement and opportunities available as the world emerges from the COVID-19 pandemic, putting data to use is critical for healthcare and the pharmaceutical industry. In an increasingly digital-first world, the way that HCPs engage with organisations, conduct research, and search for information is changing.

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Terumo Pharmaceutical Solutions expands CDMO services outside Japan for global market 

Pharma Mirror

Terumo Pharmaceutical Solutions (TPS), a division of Terumo Corporation (TSE: 4543) and a leading manufacturer of injection, primary container, and infusion therapy devices, has today announced it will expand its contract development and manufacturing services for parenteral drugs to global customers. Terumo is a well-established integrated CDMO in Japan offering end-to-end services for more than 20 years, supporting customers with pre-filled syringe (PFS) design, molding, drug preparation, fill

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Boehringer recruits former Novartis’ neurosciences head as its CMO

pharmaphorum

Boehringer Ingelheim has appointed Lykke Hinsch Gylvin as its new head of medicine and chief medical officer, succeeding Mehdi Shahidi, who left the position earlier this year after three years in the role. Hinsch Gylvin – who joins Boehringer after two years at Novartis, where she was firstly medical head of ophthalmology and latterly medical head of neurosciences – started in the new position on 1 November. “It’s so exciting to be part of this company as we share our passion to del

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Reaction Biology to acquire Vyant Bio subsidiary’s operations in US

Pharmaceutical Technology

Reaction Biology (Reaction) has concluded a definitive agreement for the acquisition of the US operations of Vyant Bio subsidiary, vivoPharm. The operations of vivoPharm are based in Hershey, Pennsylvania. According to the deal, Reaction made an upfront cash payment of $5.5m at closing. Vyant Bio anticipates receiving nearly $4.4m in cash after tax and deal-linked costs, as well as incur $0.6m in exit expenses.

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