Fri.Jul 15, 2022

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Study: Intermittent Fasting Associated with Less Severe COVID-19 Complications

Pharmacy Times

People who regularly fasted for decades had lower risk of hospitalization or death from COVID-19, adding to the potential health benefits of intermittent fasting.

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California’s low-cost insulin plans receive $100m manufacturing boost

Pharmaceutical Technology

Insulin prices made the headlines again as California governor Gavin Newsom announced plans on 7 July for the state to manufacture low-cost insulin. In a budget change proposed in February and confirmed in May , California’s Department of Health Care Access and Information (HCAI) requested a one-time investment of $100 million for Newsom’s CalRx Biosimilar Insulin initiative.

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Expert Discusses Advanced Roles for Pharmacy Technicians

Pharmacy Times

Ryan Burke, PharmD, director of professional affairs at Pharmacy Technician Certification Board, discusses more advanced roles for pharmacy technicians and how they can continue to grow beyond their current roles.

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FDA clears Xalkori for inflammatory myofibroblastic tumours

pharmaphorum

Pfizer’s tyrosine kinase inhibitor Xalkori has picked up a fourth approval from the FDA, adding a new use in the treatment of a rare form of benign tumour that typically affects children and young adults. Xalkori (crizotinib) has been cleared for inflammatory myofibroblastic tumours (IMT), which appear in organs like the lung, stomach, bladder or liver.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Study: General Practitioners Lack Understanding of Zoster Vaccine Risks, Guidelines for Immunocompromised Patients

Pharmacy Times

Researchers found knowledge gaps among general practitioners regarding the administration of Zostavax, particularly for contraindicated patients who are immunocompromised.

Vaccines 123
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Akili digital therapeutic shows promise in lupus patients

pharmaphorum

Akili looks like it could bring another digital therapeutic (DTx) to market after a clinical trial backed the efficacy of its AKL-T01 in patients with the autoimmune disorder systemic lupus erythematosus (SLE). The PureTech group company – which scored the first FDA and EMA approvals for a DTx for attention-deficit hyperactivity disorder (ADHD) – is developing AKL-T01 to tackle cognitive impairments that can affect people with SLE.

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AI in IVF: a fertile field

Pharmaceutical Technology

Despite entering its fourth decade of availability, in vitro fertilization (IVF), a medical technique used to facilitate the conception of a baby for those facing fertility problems, remains an elusive dream for many. Artificial intelligence (AI) could change this, with many researchers looking to harness the technology to increase IVF’s reliability, affordability, and availability.

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Preventing the next pandemic: Infrastructure and global equity

pharmaphorum

In the final piece of a three-part series, Ben Hargreaves explores how manufacturing infrastructure was rapidly built up to the required capacity to ensure sufficient supply of COVID-19 vaccines, and what still remains to be done to improve vaccine equity globally. During the early stages of the current pandemic, much of the focus was taken by the possibility of developing a successful vaccine and around the R&D efforts required to achieve this.

Vaccines 115
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Health Canada grants approval for Moderna’s Covid-19 vaccine in children

Pharmaceutical Technology

Health Canada has granted approval for the usage of Moderna’s messenger RNA (mRNA) Covid-19 vaccine, Spikevax, in a 25µg two-dose regimen for active immunisation to prevent Covid-19 in children aged six months to five years. So far, children aged below five years were not eligible to receive the Covid-19 vaccine in Canada. The two-dose initial vaccine regimen in children of this age group is completed in one month, which is the same dosing schedule in adults, adolescents and children aged above

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Expert: Independent Pharmacies “Layered On” New Patient Services During the Pandemic

Pharmacy Times

Debbie Weitzman of Cardinal Health, discussed how independent retail pharmacies quickly adjusted during the pandemic.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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NICE unlocks use of Amarin’s Vazkepa in 425k NHS patients

pharmaphorum

Health technology assessment (HTA) agency NICE has finalised its guidance on Amarin’s Vazkepa, clearing the path for GPs to start prescribing the drug in up to 425,000 NHS patients at high cardiovascular risk because of raised triglyceride levels. The just-published final technology appraisal document recommends that Vazkepa (icosapent ethyl) can be prescribed to people in England and Wales for adult patients with high-risk cardiovascular disease and elevated levels of triglycerides (1.7 m

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Sustainable energy strategies for pharmaceutical manufacturers

European Pharmaceutical Review

The pharmaceutical sector is not typically seen as a highly polluting, ‘heavy industry’ but it is far from green. In its 2021 report Delivering a ‘Net Zero’ National Health Service , the UK’s NHS attributes as much as a quarter of its carbon footprint to medicines. A deep carbon footprint is a common hallmark of energy intensive manufacturing processes – and the manufacture of pharmaceuticals is no exception.

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Clinical Overview: Tirzepatide for Improved Glycemic Control in Type 2 Diabetes

Pharmacy Times

The FDA approved tirzepatide for the treatment of type 2 diabetes on May 13, 2022.

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Research calls for regulators to accelerate the approval of antibiotics

European Pharmaceutical Review

A report assessing the current climate for antimicrobial innovation in Brazil, India, and South Africa, reveals that removing regulatory hurdles to accelerate the approval of new antibiotics will help to improve their development and access. Antimicrobial resistance (AMR) is a growing challenge to the healthcare sector, as antibiotics are a linchpin of modern medicine.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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First 90 Days: Anjarium Biosciences' Stephen Yoo

PharmaVoice

The incoming CEO aims to build on the buzz around the company’s leading-edge gene therapy tech.

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Daily Medication Pearl: Oritavancin (Orbactiv)

Pharmacy Times

Oritavancin (Orbactiv) is indicated for the treatment of adult patients with acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms.

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Brazil grants authorisation for Sinovac’s Covid-19 vaccine in children

Pharmaceutical Technology

The Brazilian Health Regulatory Agency (Anvisa) has granted emergency use authorization for Sinovac Biotech’s Covid-19 vaccine, CoronaVac, in children aged three to five years. Subjects in this age group can receive the same vaccine dosage authorised in patients aged six to 17 years, as well as adults. Furthermore, there exists no restriction on vaccine usage in immunosuppressed children aged three to five years.

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Educating Ourselves, Identifying Biases as a Health Care Professional

Pharmacy Times

Being able to acknowledge those missteps that may have been made that may have prevented you from delivering as culturally competent care, and being able to recalibrate and to take the correction is an important step.

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Pharmaceutical Executive Podcast Wins APEX Award of Excellence

PharmExec

Podcast recognized for its excellence in apps and podcasts category.

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Study Finds Attitudes Around Older Motherhood Focus on Negative Outcomes

Pharmacy Times

Investigators argue that much of the language around women who give birth later in life is rooted in ableism and ageism and is out of step with current childbirth trends.

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UK NICE recommends Novartis’ combination therapy for breast cancer

Pharmaceutical Technology

The UK National Institute for Health and Care Excellence (NICE) has recommended Novartis Pharmaceuticals UK’s Piqray (alpelisib) along with hormonal therapy fulvestrant to treat hormone receptor+, HER2-, PIK3CA-mutated locally advanced or metastatic breast cancer. In the final draft guidance, NICE noted that the combination treatment is intended for such patients with tumour growth following the usage of combined hormonal therapy and a cancer growth inhibitor.

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FDA Approves Crizotinib for ALK-Positive Inflammatory Myofibroblastic Tumors

Pharmacy Times

Crizotinib has also been approved to treat non-small cell lung cancer that has spread to other parts of the body and is caused by a defect in either the ALK or ROS1 gene.

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Kyowa Kirin drops Nourianz follow-up KW-6356 for Parkinson’s

pharmaphorum

Despite reporting proof-of-concept results in a mid-stage trial, Kyowa Kirin has decided to discontinue development of its Parkinson’s disease candidate KW-6356, a drug in the adenosine A2A receptor antagonist class. The Japanese drugmaker said (PDF) the decision wasn’t taken for clinical reasons, as trials suggested the drug had potential as a monotherapy and in combination with levodopa in relieving both motor and non-motor symptoms of Parkinson’s.

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Top-Performing, Innovative Pharmacies Nominated for Health Mart Pharmacy of the Year

Pharmacy Times

Pharmacies have a lot of opportunities to think out of the box, to be innovative, and continue to drive that power of community that we're highlighting at the event here.

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Ophthalmic Drugs Conference

pharmaphorum

SAE Media Group’s 5th Annual. Ophthalmic Drugs Conference. 21 – 22 November 2022 | London, UK. [link]. Delving into advanced R&D and Delivery of Ocular Therapeutics. SAE Media Group’s 5th Annual Ophthalmic Drugs Conference will explore advancements in ophthalmic treatments and variety of novel drugs, which are showing good clinical trial data.

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FDA Approves Bludigo Injection for Visualization Aid in Assessment of the Ureters

Pharmacy Times

Provepharm filed its application with the agency in September 2021, and, with the new approval, its US affiliate will market the product directly in the United States.

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Teva asks SCOTUS to overturn “skinny label” verdict on GSK drug

pharmaphorum

Teva has asked the Supreme Court to look at a judgment in a $235 million patent dispute with GSK that it claims could undermine the ability of generic drugmakers to bring new products to market, and thereby help reduce drug prices. The case hinges around the concept of “ skinny labelling ” which was introduced to stop drugmakers extending the exclusivity period for their branded medicines – through a stream of new indications or patient populations – that can be protected with so-cal

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When All Cancer Treatments Options Have Been Exhausted, Expanded Access Process May Be the Next Step

Pharmacy Times

Pursuing the expanded access process for treatment may be the best option for patients who have exhausted all available FDA-approved drugs and clinical trials.

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Cardiac and Diabetic PCD Pharma Franchise Company in India

Fossil Remedies

Cardiac and Diabetic. In recent years, diabetes and heart diseases are quite common. They are called lifestyle diseases because the fundamental cause is sedentary life and lack of exercise. As the number of people affected by these problems is increasing, there is a high demand for medicines required to treat them. If you are planning to launch Cardiac Diabetic PCD Pharma Franchise, then it is the best time.

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Maintain Bone Health to Prevent Osteoporosis

Pharmacy Times

Pharmacists can recommend calcium, smoking cessation products, and vitamin D to stave off this common condition.

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Commission can rule on Illumina, Grail merger, says EU court

pharmaphorum

Illumina’s attempt to prevent the European Commission from carrying out an antitrust review of its $8 billion takeover last year of cancer diagnosis firm Grail has been defeated in an EU court. The EU General Court has ruled that the Commission can investigate the merger, unswayed by Illumina’s argument that it should have no jurisdiction over the deal because Grail does not currently have a commercial presence within the EU.

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Recruitment tool pairs pharma firms with providers to boost patient connection

Outsourcing Pharma

Clinical Trial Navigator, from AmerisourceBergen, is designed to help sponsors pair with oncology practices to boost patient recruitment opportunities.

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13th Annual PING Conference Highlights Future of UK Pharma Industry

PharmExec

Industry leaders discuss new technologies, research, and investment strategies.

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Daily OTC Pearl: Desitin

Pharmacy Times

Desitin is used to provide relief of skin irritation caused by a diaper rash.

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