Mon.Apr 17, 2023

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How To Mitigate Anorexia and Bulimia in Adolescents With Type 1 Diabetes

Drug Topics

At the 44th National Association of Pediatric Nurse Practitioners Conference, a session presented data explaining why teenagers with T1D are at high risk for developing anorexia and bulimia.

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Tafasitamab Combination Provides Prolonged, Durable Response in Patients with Aggressive DLBCL

Pharmacy Times

According to 5-year follow-up data, the combination of tafasitamab-cxix and lenalidomide produced a durable response in patients with diffuse large B-cell lymphoma.

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Updates To CDC Immunization Schedule

Drug Topics

At the 44th annual National Association of Pediatric Nurse Practitioners Conference, the CDC provided an updated immunization schedule that details new changes.

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Personalized mRNA Cancer Vaccine With Pembrolizumab Significantly Prolonged Recurrence Free Survival in Resected High-risk Melanoma

Pharmacy Times

These study results are the first to demonstrate randomized evidence that a personalized neoantigen approach could be beneficial for patients with cancer.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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New Hepatitis B Testing Guidelines Include Universal Adult Screening

Drug Topics

The CDC said that the new guidance will help identify more cases earlier for better treatment outcomes.

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Study: COVID-19 Infection Spreads Through Households Via Common Surfaces, Hands

Pharmacy Times

The data support the use of interventions at home, including frequent handwashing, physical distancing, regular surface disinfection, and wearing a mask.

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More Trending

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Critical Success Factors for Commercializing Specialty Drugs, Cell and Gene Therapies

Pharmacy Times

Although payers have become somewhat accustomed to the high cost of specialty drugs, the price tags for gene therapies are causing “sticker shock.

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Merck agrees to acquire Prometheus Biosciences for $10.8bn

Pharmaceutical Technology

Merck has signed a definitive agreement to buy clinical-stage biotechnology firm Prometheus Biosciences for $10.8bn, strengthening its immunology pipeline. The company will buy all of Prometheus Biosciences’ outstanding shares for $200 a share through a subsidiary. Prometheus Biosciences uses precision medicine to discover, develop and commercialise new therapeutic and companion diagnostic products to treat immune-mediated diseases.

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Study Suggests C. Difficile May Be a Foodborne Illness

Pharmacy Times

The 2 most hypervirulent strains of Clostridioides difficile are associated with the consumption of pork and shellfish.

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J&J Launches $50M Multiple Sclerosis Collaboration with Pipeline Therapeutics

PharmExec

J&J's Janssen Pharmaceutica NV collaborates with Pipeline Therapeutics in a $50 million licensing deal for oral MS drug PIPE-307, with potential earnings of up to $1 billion for Pipeline.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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“Tampon Tax” Represents an Inequity

Pharmacy Times

Other health essentials, such as groceries, prescriptions, some OTC medications, are tax-exempt in many states.

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NKGen Biotech signs agreement to merge with Graf Acquisition

Pharmaceutical Technology

NKGen Biotech, a clinical-stage natural killer (NK) cell therapy firm, has signed a definitive agreement to combine its business operations with Graf Acquisition. NKGen Biotech will become a publicly traded company, while Graf will be rebranded as NKGen Biotech. Graf is also anticipated to be listed on the New York Stock Exchange, NYSE American and Nasdaq under the ticker symbol ‘NKGN’.

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Pharmacy Students Experience Compounded Mental Health Stigmas

Pharmacy Times

Some classes and curricula can contribute to preexisting stigmas about drugs and treatments for mental health.

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How to get rid of a caffeine headache

The Checkup by Singlecare

If you are one of the 80% to 90% of adults who start your day with a cup of coffee, it’s likely you will encounter caffeine withdrawal at one time or another. Caffeine withdrawal usually occurs when you quit caffeine “cold turkey” and can cause unpleasant symptoms—one of the most common being a caffeine withdrawal headache. Some people with caffeine dependence get headaches if they miss their daily Starbucks latte by even an hour.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Using Robotics in the ATMP Space

ISPE

Using Robotics in the ATMP Space Trudy Patterson Mon, 04/17/2023 - 09:38 iSpeak Blog iSpeak Using Robotics in the ATMP Space Josh Russell 17 April 2023 The use of robotics to manufacture Advanced Therapy and Medicinal Products (ATMP) solves many challenges, including significantly limiting exposure to human generated contamination. There are steps to mitigate contamination points but with the strong endorsements recently made within the current revision to Annex 1 encouraging the use of robotics

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GD2-CART01 effective for children with relapsed or refractory high-risk neuroblastoma

Hospital Pharmacy Europe

A phase 1 -2 trial showed GD2-CART01 to be safe and effective for children with heavily pre-treated, relapsed or refractory neuroblastoma GD2-CART01 is both a safe and feasible treatment for children with high-risk neuroblastoma according to the findings of a phase 1 – 2 trial by Italian researchers. Neuroblastoma is responsible for 11% of paediatric cancer deaths and cells express high levels of disialoganglioside GD2.

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FDA Approves Rizatriptan Benzoate Oral Film to Treat Acute Migraine

Pharmacy Times

The efficacy and tolerability of rizatriptan for acute migraine treatment has been well established.

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Moderate dietary salt restriction lowers blood pressure in primary aldosteronism

Hospital Pharmacy Europe

Even a moderate dietary reduction of salt intake can lead to a significant reduction in blood pressure in those with primary aldosteronism German researchers have shown that a moderate dietary reduction of salt intake in patients with primary aldosteronism, gives rise to a significant reduction in blood pressure (BP). The link between intake of sodium (in the form of salt) and hypertension is widely recognised such that reducing dietary intake not only lowers BP but is also associated with a red

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FDA AdCom votes in favour of Lundbeck’s/Otsuka’s Rexulti in AAD

Pharmaceutical Technology

On 14 April 2023, experts from the US Food and Drug Administration’s (FDA) Advisory Committee (AdCom) voted largely in favour of the potential approval of Otsuka’ s and Lundbeck Pharmaceuticals’ Rexulti for the treatment of agitation associated with Alzheimer’s dementia (AAD). Serving as a joint meeting of the Psychopharmacologic Drugs AdCom and the Peripheral and Central Nervous System Drugs AdCom, experts from the committees voted nine against one in support of Rexulti’s supplemental New Drug

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Merck to develop mAb through $10.8b acquisition

European Pharmaceutical Review

Merck & Co. Inc has agreed to acquire Prometheus Biosciences for $10.8 billion. The agreement is set to help advance PRA023, a novel humanised monoclonal antibody (mAb), developed by Prometheus. Its chosen indications are ulcerative colitis (UC) and Crohn’s disease (CD) and other autoimmune conditions. Prometheus is a clinical-stage biotechnology company.

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HIMSS23: Philips, Intermountain executives call for tech partnerships focused on thoughtful innovation to address burnout

Fierce Healthcare

HIMSS23: Philips, Intermountain executives call for tech partnerships focused on thoughtful innovation to address burnout aburky Mon, 04/17/2023 - 18:20

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Opinion: OTC naloxone is a baby step toward making the life-saving medication accessible

STAT

In an attempt to make naloxone more accessible amid the massive human toll of the opioid crisis, the FDA recently approved over-the-counter naloxone. Naloxone is the one solution that has remained constant through the evolving opioid crisis. A safe and effective medication that can quickly reverse an overdose, it is a critical tool in the public health response to the opioid crisis.

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Automation to accelerate biopharma in next decade

European Pharmaceutical Review

A report on automation in the biopharma industr y has shown that the market is projected to grow at a compound annual growth rate (CAGR) of 5.7 percent during the forecast period 2023-2033. The market’s overall world revenue value will exceed $1,855.0 million in 2023, according to the data. Factors impacting the automation in the biopharma industry market The report found that 75 percent of pharmaceutical organisations want to use automated solutions more frequently.

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Q&A: What does it mean when a clinical trial is delayed? More than you think

STAT

Frank David was just starting an independent research program on cell signaling in cancer and kidney development at a lab in Boston when he realized he’d rather be doing something else. “I figured out I was more interested in how science turned into medicine than I was in actually making and discovering new science,” he recalled.

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14M people could lose dental coverage as Medicaid redeterminations restart: report

Fierce Healthcare

14M people could lose dental coverage as Medicaid redeterminations restart: report pminemyer Mon, 04/17/2023 - 15:58

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Opinion: Where are the guidelines for the production of animals with intentional genomic alterations?

STAT

Genetic engineering has the potential to transform how we raise animals for meat and other products, making food safer, improving animal health and welfare, and shrinking animal agriculture’s environmental footprint. Pigs that are less likely to induce allergic reactions in humans. Cows with short hair that are better adapted to a changing climate or others that lack horns , preventing injury to other cows or farmhands.

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HHS releases free online cybersecurity training, best practice reports for healthcare

Fierce Healthcare

HHS releases free online cybersecurity training, best practice reports for healthcare dmuoio Mon, 04/17/2023 - 15:49

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Free Uber rides helped patients keep their prenatal appointments. Now the company wants insurers to pay for it

STAT

For patients of the Community of Hope and Mary’s Center clinics in Washington, D.C., getting to their medical appointments can be a challenge — many live far from public transit or lack cars. If they’re pregnant, the fallout can be especially harmful if they miss prenatal doctor visits, risking the baby’s and mother’s health.

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Charles Redfield to step down as Walmart’s chief merchandising officer

Drug Store News

According to a Wall Street Journal report, Redfield will leave the role on May 1, and the company will announce his replacement soon.

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Combination therapy facilitates optimal stem cell collection

European Pharmaceutical Review

The combination treatment allowed the optimal numbers of stem cells to be harvested in over 92 percent of patients after two collection procedures.” When used in combination with standard stem cell therapy, motixafortide significantly increased the number of stem cells that can be harvested, results from an international Phase III trial for multiple myeloma (MM) suggest.

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Red by Kiss intros new collaborative line with Pearl the Stylist

Drug Store News

The Styler Fixer Braid collection features four products designed to help express authenticity within the beauty industry, the company said.

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Sanofi Acquisition Will Further Distribution of T1D Therapy Teplizumab-mzwv

Drug Topics

The drug is the first and only therapy to delay the onset of stage 3 type 1 diabetes.

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Red by Kiss intros new collaborative line with Pearl the Stylist

Drug Store News

The Styler Fixer Braid collection features four products designed to help express authenticity within the beauty industry, the company said.

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In Pfizer's $43B acquisition of Seagen, the biotech's patience paid off

Fierce Pharma

In Pfizer's $43B acquisition of Seagen, the biotech's patience paid off kdunleavy Mon, 04/17/2023 - 11:34

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