PTSD Therapies on the Fast Track
Drug Topics
OCTOBER 12, 2022
Several drugs with novel mechanisms of action have been put on the pathway for speedier approval decisions by the FDA. Phase 2 and 3 trials are underway.
Wed.Oct 12, 2022
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Unmet Needs in Management of C. Difficile Infection (CDI)
Pharmacy Times
OCTOBER 12, 2022
Bincy Abraham, MD, MS; Thomas Lodise, PharmD, PhD; Teena Chopra, MD, MPH; and Paul Feuerstadt, MD, share unmet needs, including access to therapies, in treatment of C. difficile infection (CDI).
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Mental, Behavioral Health Issues Call for Creative Solutions
Drug Topics
OCTOBER 12, 2022
In an ideal world, pharmacists would be able to spot patients in mental health crisis and provide appropriate solutions.
Mentoring, Supporting Others Can Help Advance Women Pharmacists
Pharmacy Times
OCTOBER 12, 2022
Nakia Eldridge, PharmD, MBA, discussed her career, the impacts of COVID-19 on women in pharmacy, and how mentorship can pave the way for more women pharmacists.
Position Your Pharmacy for Expansion
Speaker: Chris Antypas and Josh Halladay
Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.
Managing Metabolic Syndrome in Diabetes
Drug Topics
OCTOBER 12, 2022
Patients with metabolic syndrome and diabetes may be experiencing challenges outside medication management.
Opinion: Maternity care in the U.S. is in crisis. It’s time to call the midwife
STAT
OCTOBER 12, 2022
After pushing for several hours, my patient looks exhausted but happy, clutching her seconds-old newborn to her chest. As I help her put her baby to breast for the first time, she isn’t thinking about anything other than the tiny human blinking up at her. As well she shouldn’t.
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Human neurons implanted in a rodent’s brain lead a rat to water — and make it drink
STAT
OCTOBER 12, 2022
The scientist flicked on a laser, filling the rat’s brain with blue light. The rodent, true to its past two weeks of training, scampered across its glass box to a tiny spout, where it was duly rewarded with a drink of water. From the outside, this would appear to be a pretty run-of-the-mill neuroscience experiment, except for the fact that the neurons directing the rat to its thirst-quenching reward didn’t contain any rat DNA.
Adults with Moderately to Severely Active Ulcerative Colitis Maintain Higher Remission Rates with Guselkumab, Golimumab Combination Therapy
Pharmacy Times
OCTOBER 12, 2022
The VEGA study is the first randomized, controlled trial to evaluate the efficacy and safety of combination therapy with an interleukin (IL)-23p19 subunit antagonist (guselkumab) and a tumor necrosis factor-alpha (TNF?) antagonist (golimumab) in UC.
Eureka Institute to show what translational medicine can do for digital health
pharmaphorum
OCTOBER 12, 2022
It’s no secret that the healthcare system is made up of a panoply of diverse stakeholders, each with their own priorities, incentives, and motivations. Bringing those stakeholders together is an oft-lauded goal, but it’s proved easier said than done. The Eureka Institute, a Syracuse, Italy-based non-profit, is focused on addressing this disparity by providing education, research, and advocacy around the field of translational medicine.
Differences between Fecal Microbiota Transplantation Studies to Treat C. difficile Infection (CDI)
Pharmacy Times
OCTOBER 12, 2022
Experts discuss differences in designs of clinical trials of 4 emerging microbiota-based live biotherapeutics - RBX2660, SER-109, CP101, VE303, for treatment of rCDI.
What the FDA's New Dosage Guidance Means for the Future of Clinical Research
Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist
What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.
Woman of the Week: HBA’s Nikki Jones
PharmaVoice
OCTOBER 12, 2022
As the Healthcare Businesswomen’s Association’s first chief people and DEI officer, Jones is poised to tackle pay gap inequity, systemic gender bias and leadership barriers impeding women of color.
Delaying, Skipping, and Altering Vaccine Schedules: Addressing Selective Vaccination
Pharmacy Times
OCTOBER 12, 2022
Pharmacists are poised to address selective vaccination and counsel patients contemplating delaying, skipping, or seeking an alternate vaccine schedule.
Merck gets on board with Moderna cancer vaccine in $250m deal
pharmaphorum
OCTOBER 12, 2022
Shares in Moderna were ticking upwards today after Merck & Co took up an option on a personalised RNA-based cancer vaccine with a payment of $250 million. It is the first time that Merck has exercised an option in its collaboration with the mRNA vaccine specialist, first agreed in 2016 and expanded two years later to include additional candidates.
Expert Says Pharmacist Intervention Can Impact Patients' Lives
Pharmacy Times
OCTOBER 12, 2022
As part of American Pharmacist Month, Pharmacy Times is asking experts what they believe the value of the pharmacist is.
5 Reasons to Upgrade Your Pharmacy Management Software
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Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.
Investment fuels AI-driven development of breakthrough genomic medicines
pharmaphorum
OCTOBER 12, 2022
David Del Bourgo (CEO and co-founder, Whitelab Genomics) has always been passionate about introducing disruptive, innovative technologies to markets. Now, he leads Whitelab Genomics as its artificial intelligence (AI) platform powers the development of genomic therapies – an emerging field in which genetic sequences are injected into cells to target and repair damaged genes.
Study: COVID-19, Hepatitis B Co-Infection Presents Greater Risk of Abnormal Liver Function
Pharmacy Times
OCTOBER 12, 2022
Investigators find that individuals with both conditions are more likely to develop severe disease than those in the control group.
The criticality of compliance
pharmaphorum
OCTOBER 12, 2022
Remaining compliant is imperative to the life sciences industry, so adhering to regulatory requirements is mandatory. Prior to selling drugs or medical products in any country, pharmaceutical companies must prove compliance and gain the regulatory approval required by the country in which the goods will be distributed in. By remaining compliant, medicines are manufactured in line with their pre-defined and approved specifications, in order to ensure the delivery of safe and effective products to
Advice for Physicians to Manage C. Difficile Infection (CDI)
Pharmacy Times
OCTOBER 12, 2022
Experts share advice for physicians taking care of patients with C. difficile infection (CDI).
Early Menopause Could Be Linked to Type 1 and Type 2 Diabetes Diagnoses
Drug Topics
OCTOBER 12, 2022
New data indicate that a diabetes diagnosis may be associated with earlier onset of menopause.
Tip of the Week: Carefully Consider Merchandising to Supplement Pharmacy Services
Pharmacy Times
OCTOBER 12, 2022
Deciding what goods to sell and how to arrange them will dictate the patient’s interactivity and experience.
FDA authorizes updated Covid-19 boosters for kids as young as 5
STAT
OCTOBER 12, 2022
The Food and Drug Administration on Wednesday authorized updated Covid-19 boosters for kids as young as 5. Previously, the newer versions of the shots — which target both the original strain of the coronavirus as well as the dominant BA.5 form of the Omicron variant — were only available to adults and kids as young as 12.
Oncology Overview: Omidubicel Stem Cell Therapy Product
Pharmacy Times
OCTOBER 12, 2022
Omidubicel is a stem cell-based product that utilizes nicotinamide to inhibit differentiation and to increase the migration, bone marrow homing, and engraftment efficiency of hematopoietic progenitor cells.
When is a doctor not a doctor? Often, when patients address women physicians
STAT
OCTOBER 12, 2022
In her inbox on the Mayo Clinic patient portal, the dermatologist Jamison Harvey receives some messages from patients that read more like a casual text to a friend than a request for medical expertise: “Hey Jamison, can you look at this spot?” She introduces herself to patients as Dr. Harvey, the title she’s earned over 12-plus years of medical training.
DEA Drug Takeback 2022: Strategy to Capture New Patients
DiversifyRx
OCTOBER 12, 2022
Let’s explore how you can use the DEA Drug Takeback day in October to get new patients to your pharmacy for FREE! When it comes to pharmacy marketing, I am all about marketing in many different ways and using more of a guerilla marketing method as a foundation before you start paying for a bunch of advertising. National DEA Drug Takeback Day is coming up on October 29th, 2022.
Strep & Flu Testing at the Pharmacy
Digital Pharmacist
OCTOBER 12, 2022
It has been estimated that more than 78 million visits to the physician office over a 10 year period are for acute pharyngitis, and among those 15% to 30% of cases originated from Group A Streptococcus (GAS) and 2% from Influenza. In order to reduce the number of hospitalizations due to pharyngitis and reduce financial burden for patients, one way is to get access to testing and get treated in the earlier stage of the infection.
STAT+: Merck pays $250 million to license a Moderna skin-cancer vaccine candidate
STAT
OCTOBER 12, 2022
Merck on Wednesday agreed to extend an ongoing collaboration with Moderna to develop a personalized vaccine for the treatment of patients with skin cancer. Moderna is getting $250 million from Merck to secure opt-in rights to the cancer vaccine candidate, called mRNA-4157. The two companies are jointly conducting a mid-stage clinical trial that combines the customized, mRNA-based vaccine with Merck’s checkpoint inhibitor Keytruda.
Walgreens Boots Alliance reports Q4, fiscal 2022 results
Drug Store News
OCTOBER 12, 2022
WBA's fourth quarter sales from continuing operations decreased 5.3% from the year-ago quarter to $32.4 billion, a decrease of 3.2% on a constant currency basis.
Opinion: Listen: The Supreme Court set public health back 50 years. The next term could be even worse
STAT
OCTOBER 12, 2022
It took the U.S. Supreme Court just seven days last June to set back public health by 50 years. Several cases before the court this term could continue that assault. This week on the First Opinion Podcast, law professor Lawrence O. Gostin explores how these cases — some of which are not explicitly about public health — might worsen the myriad health inequalities that became so evident throughout the Covid-19 pandemic.
Could first anti-tau therapy be approved for Alzheimer’s?
European Pharmaceutical Review
OCTOBER 12, 2022
A Phase III trial evaluating TauRx Therapeutics’ oral drug hydromethylthionine mesylate (HMTM), a tau aggression inhibitor, showed the medication continued to improve cognition over a pre-treatment baseline in patients with early Alzheimer’s for the first time. It has potential to become the first DMT targeting tau to be approved for the condition, stated Pippa Salter, Senior Neurology Analyst at GlobalData.
STAT+: Triplet Therapeutics, biotech company focused on Huntington’s, quietly shuts down
STAT
OCTOBER 12, 2022
A biotech company co-founded by venture capital firm Atlas Venture has shut down after running into problems with its lead drug and raising new funding. Triplet Therapeutics, which was based in Cambridge, Mass., launched in 2019 with a $59 million Series A round from a group of VCs including Atlas, MPM Capital, and Pfizer Ventures.
HOPA President: ‘Women Excel in Team-based Care,’ Health Care Is Strongest With a Team-based Approach
Pharmacy Times
OCTOBER 12, 2022
Heidi D. Finnes, PharmD, BCOP, FHOPA, president of HOPA discusses some key recommendations to women interested in pursuing leadership roles in oncology pharmacy.
STAT+: Differences in countries’ regulations keep some cell and gene therapies from reaching patients
STAT
OCTOBER 12, 2022
CARLSBAD, Calif. — Biotech companies developing cutting-edge cell and gene therapies often are tripped up by how much regulations around these drugs vary from country to country. On Wednesday, regulators from the United States, the European Union, and Japan came together to discuss the scale of the problem — and possible solutions. It’s a wonky-sounding issue with real-world consequences.
Live Event, Awards Highlight Women Pharmacist Day
Pharmacy Times
OCTOBER 12, 2022
This year marks the fifth annual Women Pharmacist Day after it was founded in 2018.
Where the CEO of ADC Therapeutics sees ‘huge potential’ in the tech beyond oncology
PharmaVoice
OCTOBER 12, 2022
The “magic bullet” approach of ADCs has been a breakthrough in cancer care — but this excitement could be just the beginning.
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