Drug Topics

APRIL 5, 2023

The biopharmaceutical company says it is “extremely disappointed” with the results of the COURAGE-ALS study, which failed to meet primary or secondary endpoints.

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PhRMA

APRIL 5, 2023

The United States will soon reach an important milestone in the COVID-19 pandemic: the official end of the federal public health emergency (PHE). According to the U.S. Department of Health and Human Services (HHS), the COVID-19 PHE will expire on May 11, 2023. This significant transition has been made possible, in part, by the biopharmaceutical industry’s continuing efforts to research, develop and manufacture safe, effective treatments and vaccines for COVID-19.

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Vaccines Insurance 147

Drug Topics

APRIL 5, 2023

Members of the Senate Finance Committee are pushing PBMs to modernize the rules regarding out of pocket costs and competition.

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STAT

APRIL 5, 2023

On a spring day in the late 1980s, pediatrician Mark Schleiss was confronted with a difficult case: a months-old infant who had developed pneumonia. While many infants with pneumonia recover, this particular baby had grown so sick he was admitted to the ICU, where he died. The autopsy showed he had disseminated cytomegalovirus, which had caused his pneumonia and then his death.

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Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

Drug Topics

APRIL 5, 2023

Off-label drug combinations are increasingly being used in cancer treatments, but there is the potential for overlapping or additive toxicities, explained a speaker at the 2023 HOPA Annual Conference.

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Labelling 98

STAT

APRIL 5, 2023

Obesity and diabetes in mothers have traditionally been considered risk factors for the child to also develop obesity. But a new study suggests that more narrow measures of health during pregnancy could help better assess that risk. Researchers grouped pregnant women based on specific metabolic traits and found that insulin resistance was associated with the highest risk, compared with other traits such as high cholesterol and triglycerides, according to a study published in JAMA Network Open on

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STAT

APRIL 5, 2023

When I envision the U.S. health care system, the first thing that comes to mind is a Jackson Pollock painting: splashes of color chaotically surrounding white space. The splashes of color represent existing health care venues and resources; the white space represents the gaps across our system that prevent patients from gaining the right access and the right support to improve their health.

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Hospital Pharmacy Europe

APRIL 5, 2023

Dupilumab treatment produced the lowest incidence of asthma exacerbations and greatest improvements in FEV1 among three currently used mAbs Dupilumab treatment for 12 months gives rise to the lowest number of acute exacerbations and better improvements in FEV1 compared to two commonly used monoclonal antibodies (mAbs), omalizumab or mepolizumab, in adults with moderate to severe asthma, according to comparative analysis by US researchers.

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Hospitals 104

Drug Store News

APRIL 5, 2023

With Afterpay, Rite Aid customers can 'pay-in-four' at over 2,000 Rite Aid locations for all household necessities, including health and beauty, baby care and groceries.

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Fierce Healthcare

APRIL 5, 2023

Communication failures, policy noncompliance fuel jump in reported patient safety events, Joint Commission finds dmuoio Wed, 04/05/2023 - 16:35

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Communication 111

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

FDA

The Checkup by Singlecare

APRIL 5, 2023

Can’t poop? You’re not alone! Around 4 million Americans frequently experience constipation, defined by the Mayo Clinic as fewer than three bowel movements per week. While it’s normal to get backed up from time to time, constipation and chronic constipation (difficulty passing stools for more than three weeks), can cause an array of uncomfortable symptoms.

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Mayo Clinic Controlled Substances 98

Fierce Healthcare

APRIL 5, 2023

Medicaid payment for mental health services shortchanges psychiatrists in many states: study fdiamond Wed, 04/05/2023 - 15:21

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Hospital Pharmacy Europe

APRIL 5, 2023

Both black and green tea, coffee and non-alcoholic beer all appear positively associated with a reduced risk of developing multiple sclerosis Using a case-controlled study, Iranian researchers have identified that drinking black or green tea, coffee and non-alcoholic beverages are associated with a lower risk of developing multiple sclerosis (MS). Multiple sclerosis (MS) is the most common cause of neurological disability in young adults worldwide and a 2020 study estimated that, globally, some

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Compounding Hospitals 98

Pharmaceutical Technology

APRIL 5, 2023

Austrian molecular glue degraders discovery and development company Proxygen and Merck , known as MSD outside the US and Canada, have entered into a multi-year research collaboration and licence deal. Through the collaboration, the companies will work together to identify and develop molecular glue degraders against multiple therapeutic targets. MSD will make an upfront payment to Proxygen, which will also be eligible for up to $2.55bn in future payments, subject to the achievement of agreed res

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Pharmacy Management Software

Hospital Pharmacy Europe

APRIL 5, 2023

A systemic review has concluded that an AI model provides a similar diagnostic ability for hip fractures to that of experts Canadian researchers who undertook a systematic review and meta-analysis found that the diagnostic performance of an artificial intelligence (AI) model for the detection of hip fractures was no better than that of expert radiologists and surgeons.

Hospitals 98

Hospitals 98

Pharmaceutical Technology

APRIL 5, 2023

The US Food and Drug Administration (FDA) has granted emergency use authorisation (EUA) to InflaRx’s Gohibic (vilobelimab) to treat critically ill hospitalised Covid-19 adult patients. Gohibic is indicated for use in these patients within 48 hours of receiving invasive mechanical ventilation (IMV) or extracorporeal membrane oxygenation (ECMO). It is a first-in-class monoclonal anti-human complement factor C5a antibody.

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FDA Vaccines 98

Drug Store News

APRIL 5, 2023

The infusion clinic is referral-based and will provide treatments for rheumatology, gastroenterology, pulmonary, neurology, dermatology, oncology and other chronic conditions.

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STAT

APRIL 5, 2023

Roughly two million Americans are expected to receive a cancer diagnosis this year. Some members of this already vulnerable group will wind up facing what physician Andrew Schuman recently called “a tragedy happening in slow motion” — an ongoing, nationwide shortage of critical oncology drugs that routinely save or extend the lives of children and adults.

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Department of Veterans Affairs 95

Hospital Pharmacy Europe

APRIL 5, 2023

Enhanced and early treatment of infants diagnosed with atopic eczema reduces hen’s egg allergy compared to a conventional treatment approach A team of UK and Japanese researchers have found that among infants with atopic eczema, an enhanced approach, i.e., applying treatment to both clinically affected and unaffected skin, is more effective at preventing hen’s egg allergy, compared to the usual or conventional strategy of only treating clinically affected areas.

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Hospitals 97

Fierce Healthcare

APRIL 5, 2023

CMS finalizes changes to Medicare Advantage star ratings, prior authorization reforms rking Wed, 04/05/2023 - 16:14

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Med Ed 101

APRIL 5, 2023

We have had a wonderful response to our previous pharmacology crossword on diabetes so I figured I try this again. With the help of a pharmacy student, Cody Springer, we have created a free heart failure pharmacology crossword puzzle! I know some folks out there really like crossword puzzles, so I figured why not combine […] The post Free Heart Failure Pharmacology Crossword Puzzle appeared first on Med Ed 101.

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Drug Store News

APRIL 5, 2023

The new Heinz Hot varieties feature unique pepper bases with varying heat levels and include three spicy ketchup flavors, the company said.

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Fierce Healthcare

APRIL 5, 2023

Newly reintroduced Rural Hospital Support Act helps ensure struggling small hospitals' survival, AHA says dmuoio Wed, 04/05/2023 - 12:56

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Hospitals 104

Drug Topics

APRIL 5, 2023

There are some crucial differences between a good pharmacy technician and great lead technician.

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Fierce Healthcare

APRIL 5, 2023

Study: Cuts to Medicare Advantage payments may have modest impact on seniors' benefits rking Wed, 04/05/2023 - 16:35

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STAT

APRIL 5, 2023

Good morning! Jason Mast here, filling in for Ed on this fine Passover eve. Every time I sub in on this newsletter, I fear I will offend Ed and his readers’ fine-crafted coffee sensibilities with my plebeian choices. Today, we’re sipping a dark roast from a certain national chain that has decided to offer patrons unlimited coffee for, like, $11 a month.

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FDA 87

Drug Store News

APRIL 5, 2023

Coty’s philosophy brand is making a comeback with a new formulation principle, as well as a new skin-activating serum.

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STAT

APRIL 5, 2023

Three former executives at Magellan Diagnostics Inc. are charged with knowingly selling defective lead testing machines between 2013 and 2017 that generated inaccurate results for tens of thousands of children across the country and for clients of at least one international relief organization, federal prosecutors said. Amy Winslow, 51, of Needham; Reba Daoust, 66, of Amesbury; and Mohammad Hossein Maleknia,64, of Bonita Springs, Fla., are accused of knowing the devices — including its Le

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Fierce Pharma

APRIL 5, 2023

AstraZeneca says Lynparza, Imfinzi combo excels in first look at ovarian cancer trial kdunleavy Wed, 04/05/2023 - 10:46

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European Pharmaceutical Review

APRIL 5, 2023

According to a market report , the global cell and gene therapy (CGT) supply chain/ logistics market is expected to reach $3.12 billion in 2031. This translates into a promising compound annual growth rate (CAGR) of 11.2 percent during the forecast period of 2023-2031. What is driving the cell and gene therapy supply chain/logistics market? The growing need for cell and gene treatments, growing medical trials and improvements in real-time supply chain operations are predicted to enhance the qual

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Packaging Compounding 73

Drug Store News

APRIL 5, 2023

The Senate bill is the companion to H.R. 1613, introduced in March by U.S. Reps. Buddy Carter (R-Ga,), Vicente Gonzalez (D-Texas), Elise Stefanik (R-N.Y.), Deborah Ross (D-N.C.), Rick Allen (R-Ga.), and Jake Auchincloss (D-Mass.

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Pharmafile

APRIL 5, 2023

AstraZeneca has announced positive high-level results from an interim analysis of the DUO-O phase 3 trial assessing a combination of Lynparza (olaparib) and Imfinzi (durvalumab) alongside chemotherapy and bevacizumab. This combination demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) compared to chemotherapy plus bevacizumab.

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Chemotherapy Communication 72

Fierce Pharma

APRIL 5, 2023

GSK will have to pay additional royalties to AstraZeneca on cancer drug Zejula kdunleavy Wed, 04/05/2023 - 17:03

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Pharmafile

APRIL 5, 2023

The FDA has announced that it will require opioid analgesic manufacturers to provide prepaid mail-back envelopes in outpatient pharmacies and dispensers as an additional disposal option for patients.

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FDA Communication 64